Report error Found 152 with Last Name = 'young' and Initial = 'ja'
TargetPenicillin-binding protein 1A(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Displacement of fluorescent Bocillin FL from N-terminal His tagged Pseudomonas aeruginosa PAO1 PBP1a (residues 36 to 822) expressed in Escherichia co...More data for this Ligand-Target Pair
TargetPenicillin-binding protein 1A(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 46nMAssay Description:Displacement of fluorescent Bocillin FL from N-terminal His tagged Pseudomonas aeruginosa PAO1 PBP1a (residues 36 to 822) expressed in Escherichia co...More data for this Ligand-Target Pair
TargetPenicillin-binding protein 1A(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 46nMAssay Description:Displacement of fluorescent Bocillin FL from N-terminal His tagged Pseudomonas aeruginosa PAO1 PBP1a (residues 36 to 822) expressed in Escherichia co...More data for this Ligand-Target Pair
TargetPenicillin-binding protein 1A(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 46nMAssay Description:Displacement of fluorescent Bocillin FL from N-terminal His tagged Pseudomonas aeruginosa PAO1 PBP1a (residues 36 to 822) expressed in Escherichia co...More data for this Ligand-Target Pair
TargetPenicillin-binding protein 1A(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 46nMAssay Description:Displacement of fluorescent Bocillin FL from N-terminal His tagged Pseudomonas aeruginosa PAO1 PBP1a (residues 36 to 822) expressed in Escherichia co...More data for this Ligand-Target Pair
TargetPenicillin-binding protein 1A(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 65nMAssay Description:Displacement of fluorescent Bocillin FL from N-terminal His tagged Pseudomonas aeruginosa PAO1 PBP1a (residues 36 to 822) expressed in Escherichia co...More data for this Ligand-Target Pair
Affinity DataKd: 81nMAssay Description:Binding affinity to recombinant GID4 (unknown origin) assessed as dissociation constant by surface plasmon resonance assayMore data for this Ligand-Target Pair
TargetPenicillin-binding protein 1A(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 110nMAssay Description:Displacement of fluorescent Bocillin FL from N-terminal His tagged Pseudomonas aeruginosa PAO1 PBP1a (residues 36 to 822) expressed in Escherichia co...More data for this Ligand-Target Pair
Affinity DataKd: 300nMAssay Description:Binding affinity to recombinant GID4 (unknown origin) assessed as dissociation constant by surface plasmon resonance assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataKd: 500nMAssay Description:Binding affinity to recombinant GID4 (unknown origin) assessed as dissociation constant by surface plasmon resonance assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataKd: 2.30E+3nMAssay Description:Binding affinity to recombinant GID4 (unknown origin) assessed as dissociation constant by surface plasmon resonance assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+3nMAssay Description:Displacement of C-terminal NanoLuc-tagged MPGLWKS peptide from N-terminal HaloTag-tagged GID4 (unknown origin) expressed in HEK293T cells incubated f...More data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataKd: 2.70E+3nMAssay Description:Binding affinity to recombinant GID4 (unknown origin) assessed as dissociation constant by surface plasmon resonance assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
TargetPenicillin-binding protein 1A(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 3.34E+3nMAssay Description:Displacement of fluorescent Bocillin FL from N-terminal His tagged Pseudomonas aeruginosa PAO1 PBP1a (residues 36 to 822) expressed in Escherichia co...More data for this Ligand-Target Pair
Affinity DataKd: 3.40E+3nMAssay Description:Binding affinity to recombinant GID4 (unknown origin) assessed as dissociation constant by surface plasmon resonance assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Human)
China Innovation Center of Roche
Curated by ChEMBL
China Innovation Center of Roche
Curated by ChEMBL
Affinity DataIC50: 7.80E+3nMAssay Description:Inhibition of hERG stably expressed in CHO cells by whole-cell voltage-clamp assayMore data for this Ligand-Target Pair
Affinity DataKd: 9.00E+3nMAssay Description:Binding affinity to recombinant GID4 (unknown origin) assessed as dissociation constant by surface plasmon resonance assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
TargetPotassium voltage-gated channel subfamily H member 2(Human)
China Innovation Center of Roche
Curated by ChEMBL
China Innovation Center of Roche
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of hERG stably expressed in CHO cells by whole-cell voltage-clamp assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Human)
China Innovation Center of Roche
Curated by ChEMBL
China Innovation Center of Roche
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of hERG stably expressed in CHO cells by whole-cell voltage-clamp assayMore data for this Ligand-Target Pair
Affinity DataKd: 1.50E+4nMAssay Description:Binding affinity to recombinant GID4 (unknown origin) assessed as dissociation constant by surface plasmon resonance assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
TargetPotassium voltage-gated channel subfamily H member 2(Human)
China Innovation Center of Roche
Curated by ChEMBL
China Innovation Center of Roche
Curated by ChEMBL
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of hERG stably expressed in CHO cells by whole-cell voltage-clamp assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Human)
China Innovation Center of Roche
Curated by ChEMBL
China Innovation Center of Roche
Curated by ChEMBL
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of hERG stably expressed in CHO cells by whole-cell voltage-clamp assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Human)
China Innovation Center of Roche
Curated by ChEMBL
China Innovation Center of Roche
Curated by ChEMBL
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of hERG stably expressed in CHO cells by whole-cell voltage-clamp assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Human)
China Innovation Center of Roche
Curated by ChEMBL
China Innovation Center of Roche
Curated by ChEMBL
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of hERG stably expressed in CHO cells by whole-cell voltage-clamp assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Human)
China Innovation Center of Roche
Curated by ChEMBL
China Innovation Center of Roche
Curated by ChEMBL
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of hERG stably expressed in CHO cells by whole-cell voltage-clamp assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Human)
China Innovation Center of Roche
Curated by ChEMBL
China Innovation Center of Roche
Curated by ChEMBL
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of hERG stably expressed in CHO cells by whole-cell voltage-clamp assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Human)
China Innovation Center of Roche
Curated by ChEMBL
China Innovation Center of Roche
Curated by ChEMBL
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of hERG stably expressed in CHO cells by whole-cell voltage-clamp assayMore data for this Ligand-Target Pair
Affinity DataKd: 2.40E+4nMAssay Description:Binding affinity to recombinant GID4 (unknown origin) assessed as dissociation constant by surface plasmon resonance assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
TargetBaculoviral IAP repeat-containing protein 7(Human)
Sanford Burnham Prebys Medical Discovery Institute
US Patent
Sanford Burnham Prebys Medical Discovery Institute
US Patent
Affinity DataKi: <2.50E+4nMAssay Description:5000 PPC-1 cells were plated and grown overnight. Compounds were plated and 4 hrs later, TRAIL was added to half of the plate while RPMI was added to...More data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase XIAP [241-356](Human)
Sanford Burnham Prebys Medical Discovery Institute
US Patent
Sanford Burnham Prebys Medical Discovery Institute
US Patent
Affinity DataKi: <2.50E+4nMAssay Description:5000 PPC-1 cells were plated and grown overnight. Compounds were plated and 4 hrs later, TRAIL was added to half of the plate while RPMI was added to...More data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase XIAP [241-356](Human)
Sanford Burnham Prebys Medical Discovery Institute
US Patent
Sanford Burnham Prebys Medical Discovery Institute
US Patent
Affinity DataKi: <2.50E+4nMAssay Description:5000 PPC-1 cells were plated and grown overnight. Compounds were plated and 4 hrs later, TRAIL was added to half of the plate while RPMI was added to...More data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase XIAP [1-168]/[124-242](Human)
Sanford Burnham Prebys Medical Discovery Institute
US Patent
Sanford Burnham Prebys Medical Discovery Institute
US Patent
Affinity DataKi: <2.50E+4nMAssay Description:5000 PPC-1 cells were plated and grown overnight. Compounds were plated and 4 hrs later, TRAIL was added to half of the plate while RPMI was added to...More data for this Ligand-Target Pair
TargetBaculoviral IAP repeat-containing protein 7(Human)
Sanford Burnham Prebys Medical Discovery Institute
US Patent
Sanford Burnham Prebys Medical Discovery Institute
US Patent
Affinity DataKi: <2.50E+4nMAssay Description:5000 PPC-1 cells were plated and grown overnight. Compounds were plated and 4 hrs later, TRAIL was added to half of the plate while RPMI was added to...More data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase XIAP [241-356](Human)
Sanford Burnham Prebys Medical Discovery Institute
US Patent
Sanford Burnham Prebys Medical Discovery Institute
US Patent
Affinity DataKi: <2.50E+4nMAssay Description:5000 PPC-1 cells were plated and grown overnight. Compounds were plated and 4 hrs later, TRAIL was added to half of the plate while RPMI was added to...More data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase XIAP [1-168]/[124-242](Human)
Sanford Burnham Prebys Medical Discovery Institute
US Patent
Sanford Burnham Prebys Medical Discovery Institute
US Patent
Affinity DataKi: <2.50E+4nMAssay Description:5000 PPC-1 cells were plated and grown overnight. Compounds were plated and 4 hrs later, TRAIL was added to half of the plate while RPMI was added to...More data for this Ligand-Target Pair
TargetBaculoviral IAP repeat-containing protein 7(Human)
Sanford Burnham Prebys Medical Discovery Institute
US Patent
Sanford Burnham Prebys Medical Discovery Institute
US Patent
Affinity DataKi: <2.50E+4nMAssay Description:5000 PPC-1 cells were plated and grown overnight. Compounds were plated and 4 hrs later, TRAIL was added to half of the plate while RPMI was added to...More data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase XIAP [241-356](Human)
Sanford Burnham Prebys Medical Discovery Institute
US Patent
Sanford Burnham Prebys Medical Discovery Institute
US Patent
Affinity DataKi: <2.50E+4nMAssay Description:5000 PPC-1 cells were plated and grown overnight. Compounds were plated and 4 hrs later, TRAIL was added to half of the plate while RPMI was added to...More data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase XIAP [1-168]/[124-242](Human)
Sanford Burnham Prebys Medical Discovery Institute
US Patent
Sanford Burnham Prebys Medical Discovery Institute
US Patent
Affinity DataKi: <2.50E+4nMAssay Description:5000 PPC-1 cells were plated and grown overnight. Compounds were plated and 4 hrs later, TRAIL was added to half of the plate while RPMI was added to...More data for this Ligand-Target Pair
TargetBaculoviral IAP repeat-containing protein 7(Human)
Sanford Burnham Prebys Medical Discovery Institute
US Patent
Sanford Burnham Prebys Medical Discovery Institute
US Patent
Affinity DataKi: <2.50E+4nMAssay Description:5000 PPC-1 cells were plated and grown overnight. Compounds were plated and 4 hrs later, TRAIL was added to half of the plate while RPMI was added to...More data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase XIAP [241-356](Human)
Sanford Burnham Prebys Medical Discovery Institute
US Patent
Sanford Burnham Prebys Medical Discovery Institute
US Patent
Affinity DataKi: <2.50E+4nMAssay Description:5000 PPC-1 cells were plated and grown overnight. Compounds were plated and 4 hrs later, TRAIL was added to half of the plate while RPMI was added to...More data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase XIAP [241-356](Human)
Sanford Burnham Prebys Medical Discovery Institute
US Patent
Sanford Burnham Prebys Medical Discovery Institute
US Patent
Affinity DataKi: <2.50E+4nMAssay Description:5000 PPC-1 cells were plated and grown overnight. Compounds were plated and 4 hrs later, TRAIL was added to half of the plate while RPMI was added to...More data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase XIAP [1-168]/[124-242](Human)
Sanford Burnham Prebys Medical Discovery Institute
US Patent
Sanford Burnham Prebys Medical Discovery Institute
US Patent
Affinity DataKi: <2.50E+4nMAssay Description:5000 PPC-1 cells were plated and grown overnight. Compounds were plated and 4 hrs later, TRAIL was added to half of the plate while RPMI was added to...More data for this Ligand-Target Pair
TargetBaculoviral IAP repeat-containing protein 7(Human)
Sanford Burnham Prebys Medical Discovery Institute
US Patent
Sanford Burnham Prebys Medical Discovery Institute
US Patent
Affinity DataKi: <2.50E+4nMAssay Description:5000 PPC-1 cells were plated and grown overnight. Compounds were plated and 4 hrs later, TRAIL was added to half of the plate while RPMI was added to...More data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase XIAP [241-356](Human)
Sanford Burnham Prebys Medical Discovery Institute
US Patent
Sanford Burnham Prebys Medical Discovery Institute
US Patent
Affinity DataKi: <2.50E+4nMAssay Description:5000 PPC-1 cells were plated and grown overnight. Compounds were plated and 4 hrs later, TRAIL was added to half of the plate while RPMI was added to...More data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase XIAP [241-356](Human)
Sanford Burnham Prebys Medical Discovery Institute
US Patent
Sanford Burnham Prebys Medical Discovery Institute
US Patent
Affinity DataKi: <2.50E+4nMAssay Description:5000 PPC-1 cells were plated and grown overnight. Compounds were plated and 4 hrs later, TRAIL was added to half of the plate while RPMI was added to...More data for this Ligand-Target Pair
TargetBaculoviral IAP repeat-containing protein 7(Human)
Sanford Burnham Prebys Medical Discovery Institute
US Patent
Sanford Burnham Prebys Medical Discovery Institute
US Patent
Affinity DataKi: <2.50E+4nMAssay Description:5000 PPC-1 cells were plated and grown overnight. Compounds were plated and 4 hrs later, TRAIL was added to half of the plate while RPMI was added to...More data for this Ligand-Target Pair
TargetBaculoviral IAP repeat-containing protein 7(Human)
Sanford Burnham Prebys Medical Discovery Institute
US Patent
Sanford Burnham Prebys Medical Discovery Institute
US Patent
Affinity DataKi: <2.50E+4nMAssay Description:5000 PPC-1 cells were plated and grown overnight. Compounds were plated and 4 hrs later, TRAIL was added to half of the plate while RPMI was added to...More data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase XIAP [241-356](Human)
Sanford Burnham Prebys Medical Discovery Institute
US Patent
Sanford Burnham Prebys Medical Discovery Institute
US Patent
Affinity DataKi: <2.50E+4nMAssay Description:5000 PPC-1 cells were plated and grown overnight. Compounds were plated and 4 hrs later, TRAIL was added to half of the plate while RPMI was added to...More data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase XIAP [241-356](Human)
Sanford Burnham Prebys Medical Discovery Institute
US Patent
Sanford Burnham Prebys Medical Discovery Institute
US Patent
Affinity DataKi: <2.50E+4nMAssay Description:5000 PPC-1 cells were plated and grown overnight. Compounds were plated and 4 hrs later, TRAIL was added to half of the plate while RPMI was added to...More data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase XIAP [241-356](Human)
Sanford Burnham Prebys Medical Discovery Institute
US Patent
Sanford Burnham Prebys Medical Discovery Institute
US Patent
Affinity DataKi: <2.50E+4nMAssay Description:5000 PPC-1 cells were plated and grown overnight. Compounds were plated and 4 hrs later, TRAIL was added to half of the plate while RPMI was added to...More data for this Ligand-Target Pair














3D Structure (crystal)






















