Compile Data Set for Download or QSAR
Report error Found 34 of ki for UniProtKB: P00390
TargetGlutathione reductase, mitochondrial(Human)
Batman University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50352164BDBM50352164(CHEMBL1824793)
Affinity DataKi:  211nMAssay Description:Competitive inhibition of human erythrocyte Glutathione reductase using GSSG substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2013
Entry Details Article
PubMed
TargetGlutathione reductase, mitochondrial(Human)
Batman University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 94597BDBM94597((Z)-2-butenedioate;10-(1-methyl-4-piperidinylidene...)
Affinity DataKi:  800nM ΔG°:  -8.31kcal/mole IC50: 1.20E+4nMpH: 8.0 T: 2°CAssay Description:GR activity was determined by the method of Carlberg and Mannervik [Carlberg et al., FL:Academic Press, 72:248-254] with a Shimadzu Spectrophotometer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details Article
PubMed
TargetGlutathione reductase, mitochondrial(Human)
Batman University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50096018BDBM50096018(6-(3-METHYL-1,4-DIOXO-1,4-DIHYDRONAPHTHALEN-2-YL)H...)
Affinity DataKi:  3.70E+3nMAssay Description:Inhibitory concentration against human glutathione reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutathione reductase, mitochondrial(Human)
Batman University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50352161BDBM50352161(CHEMBL1824791)
Affinity DataKi:  4.16E+3nMAssay Description:Non-Competitive inhibition of human erythrocyte Glutathione reductase using GSSG substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2013
Entry Details Article
PubMed
TargetGlutathione reductase, mitochondrial(Human)
Batman University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50352163BDBM50352163(CHEMBL1824792)
Affinity DataKi:  4.57E+3nMAssay Description:Competitive inhibition of human erythrocyte Glutathione reductase using GSSG substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2013
Entry Details Article
PubMed
TargetGlutathione reductase, mitochondrial(Human)
Batman University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50056998BDBM50056998(Meloxicam sodium | 4-Hydroxy-2-methyl-1,1-dioxo-1,...)
Affinity DataKi:  6.10E+3nM ΔG°:  -7.11kcal/mole IC50: 2.90E+4nMpH: 8.0 T: 2°CAssay Description:GR activity was determined by the method of Carlberg and Mannervik [Carlberg et al., FL:Academic Press, 72:248-254] with a Shimadzu Spectrophotometer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details Article
PubMed
TargetGlutathione reductase, mitochondrial(Human)
Batman University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50422689BDBM50422689(640/359 | CEFUROXIME)
Affinity DataKi:  1.04E+4nM IC50: 1.88E+4nMpH: 8.0Assay Description:Enzymatic activity was measured by Beutler's method with a Shimadzu Spectrophotometer UV-(1208), at 25°C. The assay system contained 100 mM Tris-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2017
Entry Details Article
PubMed
TargetGlutathione reductase, mitochondrial(Human)
Batman University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50316592BDBM50316592((2R(S),7R(S))-7-Hydroxybicyclo[2.2.1]heptan-2-yl n...)
Affinity DataKi:  1.17E+4nMAssay Description:Inhibition of human erythrocyte glutathione reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2012
Entry Details Article
PubMed
TargetGlutathione reductase, mitochondrial(Human)
Batman University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 24778BDBM24778(Vitamin K3 | cid_4055 | 2-methyl-1,4-dihydronaphth...)
Affinity DataKi:  1.21E+4nMAssay Description:Inhibitory concentration against human glutathione reductase (In presence of glutathione disulfide)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutathione reductase, mitochondrial(Human)
Batman University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50293668BDBM50293668((2S(R),7R(S))-7-Hydroxybicyclo[2.2.1]heptan-2-yl n...)
Affinity DataKi:  1.31E+4nMAssay Description:Inhibition of human erythrocyte glutathione reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2012
Entry Details Article
PubMed
TargetGlutathione reductase, mitochondrial(Human)
Batman University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 24778BDBM24778(Vitamin K3 | cid_4055 | 2-methyl-1,4-dihydronaphth...)
Affinity DataKi:  1.61E+4nMAssay Description:Inhibitory concentration against human glutathione reductase (In presence of NADPH)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutathione reductase, mitochondrial(Human)
Batman University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50049707BDBM50049707((6R,7R)-7-{2-(2-Amino-thiazol-4-yl)-2-[(Z)-methoxy...)
Affinity DataKi:  1.73E+4nM IC50: 2.13E+4nMpH: 8.0Assay Description:Enzymatic activity was measured by Beutler's method with a Shimadzu Spectrophotometer UV-(1208), at 25°C. The assay system contained 100 mM Tris-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2017
Entry Details Article
PubMed
TargetGlutathione reductase, mitochondrial(Human)
Batman University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50336640BDBM50336640((nifedipine) 2,6-Dimethyl-4-(2-nitro-phenyl)-1,4-d...)
Affinity DataKi:  1.74E+4nMAssay Description:Competitive inhibition of human erythrocyte Glutathione reductase using GSSG substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2013
Entry Details Article
PubMed
TargetGlutathione reductase, mitochondrial(Human)
Batman University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50293667BDBM50293667((1R(S),2R(S),3S(R),4S(R))-2,3-Dihydroxycyclo-hexan...)
Affinity DataKi:  1.74E+4nMAssay Description:Inhibition of human erythrocyte glutathione reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2012
Entry Details Article
PubMed
TargetGlutathione reductase, mitochondrial(Human)
Batman University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50293666BDBM50293666((1S(R),3S(R),4S(R),6S(R))-4,6-Dihydroxycyclo-hexan...)
Affinity DataKi:  1.79E+4nMAssay Description:Inhibition of human erythrocyte glutathione reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2012
Entry Details Article
PubMed
TargetGlutathione reductase, mitochondrial(Human)
Batman University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50293665BDBM50293665((1R(S),2R(S),4R(S),5R(S))-2,5-Dihydroxycyclo-hexan...)
Affinity DataKi:  1.84E+4nMAssay Description:Inhibition of human erythrocyte glutathione reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2012
Entry Details Article
PubMed
TargetGlutathione reductase, mitochondrial(Human)
Batman University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50293664BDBM50293664(9(R(S))-Hydroxy-1,2,3,4-tetrahydro-1,4-methano-nap...)
Affinity DataKi:  1.88E+4nMAssay Description:Inhibition of human erythrocyte glutathione reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2012
Entry Details Article
PubMed
TargetGlutathione reductase, mitochondrial(Human)
Batman University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50293663BDBM50293663((1S(R),2S(R),5R(S),6R(S))-5-Bromo-9-oxabicyclo[4.2...)
Affinity DataKi:  2.15E+4nMAssay Description:Inhibition of human erythrocyte glutathione reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2012
Entry Details Article
PubMed
TargetGlutathione reductase, mitochondrial(Human)
Batman University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50293661BDBM50293661(trans-(1S(R),2S(R))-2-Hydroxycyclooctylnitrate | t...)
Affinity DataKi:  2.19E+4nMAssay Description:Inhibition of human erythrocyte glutathione reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2012
Entry Details Article
PubMed
TargetGlutathione reductase, mitochondrial(Human)
Batman University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 237182BDBM237182(Ceftizoxime)
Affinity DataKi:  2.28E+4nM IC50: 3.97E+4nMpH: 8.0Assay Description:Enzymatic activity was measured by Beutler's method with a Shimadzu Spectrophotometer UV-(1208), at 25°C. The assay system contained 100 mM Tris-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2017
Entry Details Article
PubMed
TargetGlutathione reductase, mitochondrial(Human)
Batman University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50293660BDBM50293660(trans-(R(S))-2-Hydroxy-1-phenylethylnitrate | tran...)
Affinity DataKi:  2.56E+4nMAssay Description:Inhibition of human erythrocyte glutathione reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2012
Entry Details Article
PubMed
TargetGlutathione reductase, mitochondrial(Human)
Batman University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50390999BDBM50390999(CEFOPERAZONE)
Affinity DataKi:  2.87E+4nM IC50: 4.84E+4nMpH: 8.0Assay Description:Enzymatic activity was measured by Beutler's method with a Shimadzu Spectrophotometer UV-(1208), at 25°C. The assay system contained 100 mM Tris-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2017
Entry Details Article
PubMed
TargetGlutathione reductase, mitochondrial(Human)
Batman University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50293658BDBM50293658(trans-(1S(R),6S(R))-6-Hydroxycyclohex-3-enyl nitra...)
Affinity DataKi:  3.51E+4nMAssay Description:Inhibition of human erythrocyte glutathione reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2012
Entry Details Article
PubMed
TargetGlutathione reductase, mitochondrial(Human)
Batman University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 17657BDBM17657(L-Glutamic acid | L-Glu | (2S)-2-aminopentanedioic...)
Affinity DataKi:  4.27E+4nMAssay Description:Competitive inhibition of human erythrocyte Glutathione reductase using GSSG substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2013
Entry Details Article
PubMed
TargetGlutathione reductase, mitochondrial(Human)
Batman University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50293659BDBM50293659(trans-(1S(R),2S(R))-2-Hydroxycyclohexylnitrate | t...)
Affinity DataKi:  4.37E+4nMAssay Description:Inhibition of human erythrocyte glutathione reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2012
Entry Details Article
PubMed
TargetGlutathione reductase, mitochondrial(Human)
Batman University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50293662BDBM50293662(trans-(1S(R),8S(R),Z)-8-Hydroxycyclooct-4-enyl nit...)
Affinity DataKi:  4.43E+4nMAssay Description:Inhibition of human erythrocyte glutathione reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2012
Entry Details Article
PubMed
TargetGlutathione reductase, mitochondrial(Human)
Batman University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50352165BDBM50352165(LYSINE)
Affinity DataKi:  5.46E+4nMAssay Description:Competitive inhibition of human erythrocyte Glutathione reductase using GSSG substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2013
Entry Details Article
PubMed
TargetGlutathione reductase, mitochondrial(Human)
Batman University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50170723BDBM50170723(N',N'''''-hexane-1,6-diylbis[N-(4-chlorophenyl)(im...)
Affinity DataKi:  1.92E+5nMAssay Description:Inhibitory constant against human glutathione reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetGlutathione reductase, mitochondrial(Human)
Batman University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50352162BDBM50352162(NITROBENZENE)
Affinity DataKi:  2.74E+5nMAssay Description:Competitive inhibition of human erythrocyte Glutathione reductase using GSSG substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2013
Entry Details Article
PubMed
TargetGlutathione reductase, mitochondrial(Human)
Batman University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 235694BDBM235694(Phenyramidol-HCl)
Affinity DataKi:  4.34E+5nM ΔG°:  -4.58kcal/mole IC50: 9.90E+5nMpH: 8.0 T: 2°CAssay Description:GR activity was determined by the method of Carlberg and Mannervik [Carlberg et al., FL:Academic Press, 72:248-254] with a Shimadzu Spectrophotometer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details Article
PubMed
TargetGlutathione reductase, mitochondrial(Human)
Batman University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50091152BDBM50091152([3-(2-Chloro-phenothiazin-10-yl)-propyl]-cyclohexy...)
Affinity DataKi:  2.00E+6nMAssay Description:Inhibitory activity against Human Erythrocyte glutathione reductase (GR).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetGlutathione reductase, mitochondrial(Human)
Batman University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50091149BDBM50091149((4-Chloro-benzyl)-[3-(2-chloro-phenothiazin-10-yl)...)
Affinity DataKi:  2.20E+6nMAssay Description:Inhibitory activity against Human Erythrocyte glutathione reductase (GR).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetGlutathione reductase, mitochondrial(Human)
Batman University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50093207BDBM50093207((E)-3-(3,4-Dihydroxy-phenyl)-N-[3-(4-{3-[(E)-3-(3,...)
Affinity DataKi: >1.00E+7nMAssay Description:The compound was evaluated for inhibition of human Glutathione reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetGlutathione reductase, mitochondrial(Human)
Batman University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 233150BDBM233150(Gadopentetic acid)
Affinity DataKi:  2.88E+7nM ΔG°:  -2.10kcal/mole IC50: 1.38E+8nMpH: 8.0 T: 2°CAssay Description:GR activity was determined by the method of Carlberg and Mannervik [Carlberg et al., FL:Academic Press, 72:248-254] with a Shimadzu Spectrophotometer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details Article
PubMed