Compile Data Set for Download or QSAR
maximum 50k data
Found 25 of ec50 for UniProtKB: Q13464
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Kalypsys

Curated by ChEMBL
LigandPNGBDBM50319035((+/-)-4-(5-(1-aminobutyl)-3-methylbenzo[b]thiophen...)
Affinity DataEC50:  600nMAssay Description:Inhibition of ROCK1 in human GTM3 cells by impedance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Kalypsys

Curated by ChEMBL
LigandPNGBDBM50319005((R)-4-(1-aminoethyl)-N-(1H-pyrrolo[2,3-b]pyridin-4...)
Affinity DataEC50:  790nMAssay Description:Inhibition of ROCK1 in human GTM3 cells by impedance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Kalypsys

Curated by ChEMBL
LigandPNGBDBM50319027((+/-)-3-(amino(2-(2-aminopyrimidin-4-yl)-3-methylb...)
Affinity DataEC50:  900nMAssay Description:Inhibition of ROCK1 in human GTM3 cells by impedance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Kalypsys

Curated by ChEMBL
LigandPNGBDBM50319025(3-(2-(2-aminopyrimidin-4-yl)-3-methylbenzo[b]thiop...)
Affinity DataEC50:  1.00E+3nMAssay Description:Inhibition of ROCK1 in human GTM3 cells by impedance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Kalypsys

Curated by ChEMBL
LigandPNGBDBM50319037((+/-)-4-(5-(1-amino-3-methylbutyl)-3-methylbenzo[b...)
Affinity DataEC50:  1.40E+3nMAssay Description:Inhibition of ROCK1 in human GTM3 cells by impedance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Kalypsys

Curated by ChEMBL
LigandPNGBDBM50319031((+/-)-4-(5-(amino(phenyl)methyl)-3-methylbenzo[b]t...)
Affinity DataEC50:  1.40E+3nMAssay Description:Inhibition of ROCK1 in human GTM3 cells by impedance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Kalypsys

Curated by ChEMBL
LigandPNGBDBM50319034((+/-)-4-(5-(1-aminopropyl)-3-methylbenzo[b]thiophe...)
Affinity DataEC50:  1.70E+3nMAssay Description:Inhibition of ROCK1 in human GTM3 cells by impedance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Kalypsys

Curated by ChEMBL
LigandPNGBDBM50319030((+/-)--4-(5-(amino(m-tolyl)methyl)-3-methylbenzo[b...)
Affinity DataEC50:  1.90E+3nMAssay Description:Inhibition of ROCK1 in human GTM3 cells by impedance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Kalypsys

Curated by ChEMBL
LigandPNGBDBM50319036((+/-)-4-(5-(1-amino-2-methylpropyl)-3-methylbenzo[...)
Affinity DataEC50:  2.10E+3nMAssay Description:Inhibition of ROCK1 in human GTM3 cells by impedance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Kalypsys

Curated by ChEMBL
LigandPNGBDBM50319028((+/-)--4-(5-(amino(4-methoxyphenyl)methyl)-3-methy...)
Affinity DataEC50:  2.60E+3nMAssay Description:Inhibition of ROCK1 in human GTM3 cells by impedance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Kalypsys

Curated by ChEMBL
LigandPNGBDBM50319029((+/-)--4-(5-(amino(3-chlorophenyl)methyl)-3-methyl...)
Affinity DataEC50:  2.70E+3nMAssay Description:Inhibition of ROCK1 in human GTM3 cells by impedance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Kalypsys

Curated by ChEMBL
LigandPNGBDBM50319021(3-((2-(2-aminopyrimidin-4-yl)-3-methylbenzo[b]thio...)
Affinity DataEC50:  2.90E+3nMAssay Description:Inhibition of ROCK1 in human GTM3 cells by impedance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Kalypsys

Curated by ChEMBL
LigandPNGBDBM50319026((+/-)-4-(5-(amino(3-methoxyphenyl)methyl)-3-methyl...)
Affinity DataEC50:  3.60E+3nMAssay Description:Inhibition of ROCK1 in human GTM3 cells by impedance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Kalypsys

Curated by ChEMBL
LigandPNGBDBM50319033((+/-)-4-(5-(1-aminoethyl)-3-methylbenzo[b]thiophen...)
Affinity DataEC50:  4.20E+3nMAssay Description:Inhibition of ROCK1 in human GTM3 cells by impedance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Kalypsys

Curated by ChEMBL
LigandPNGBDBM50319017(4-(5-(2-methoxybenzyl)-3-methylbenzo[b]thiophen-2-...)
Affinity DataEC50: >1.00E+4nMAssay Description:Inhibition of ROCK1 in human GTM3 cells by impedance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Kalypsys

Curated by ChEMBL
LigandPNGBDBM50319032(4-(5-(aminomethyl)-3-methylbenzo[b]thiophen-2-yl)p...)
Affinity DataEC50: >1.00E+4nMAssay Description:Inhibition of ROCK1 in human GTM3 cells by impedance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Kalypsys

Curated by ChEMBL
LigandPNGBDBM50319016(4-(5-benzyl-3-methylbenzo[b]thiophen-2-yl)pyrimidi...)
Affinity DataEC50: >1.00E+4nMAssay Description:Inhibition of ROCK1 in human GTM3 cells by impedance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Kalypsys

Curated by ChEMBL
LigandPNGBDBM50319015(4-(3-methyl-5-phenylbenzo[b]thiophen-2-yl)pyrimidi...)
Affinity DataEC50: >1.00E+4nMAssay Description:Inhibition of ROCK1 in human GTM3 cells by impedance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Kalypsys

Curated by ChEMBL
LigandPNGBDBM50319014(4-(3-methylbenzo[b]thiophen-2-yl)pyrimidin-2-amine...)
Affinity DataEC50: >1.00E+4nMAssay Description:Inhibition of ROCK1 in human GTM3 cells by impedance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Kalypsys

Curated by ChEMBL
LigandPNGBDBM50319018(4-(5-(3-methoxybenzyl)-3-methylbenzo[b]thiophen-2-...)
Affinity DataEC50: >1.00E+4nMAssay Description:Inhibition of ROCK1 in human GTM3 cells by impedance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Kalypsys

Curated by ChEMBL
LigandPNGBDBM50319019(4-(5-(4-methoxybenzyl)-3-methylbenzo[b]thiophen-2-...)
Affinity DataEC50: >1.00E+4nMAssay Description:Inhibition of ROCK1 in human GTM3 cells by impedance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Kalypsys

Curated by ChEMBL
LigandPNGBDBM50319020(4-(3-methyl-5-(3-(trifluoromethyl)benzyl)benzo[b]t...)
Affinity DataEC50: >1.00E+4nMAssay Description:Inhibition of ROCK1 in human GTM3 cells by impedance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Kalypsys

Curated by ChEMBL
LigandPNGBDBM50319024(3-(2-(2-aminopyrimidin-4-yl)-3-methylbenzo[b]thiop...)
Affinity DataEC50: >1.00E+4nMAssay Description:Inhibition of ROCK1 in human GTM3 cells by impedance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Kalypsys

Curated by ChEMBL
LigandPNGBDBM50319022(3-((2-(2-aminopyrimidin-4-yl)-3-methylbenzo[b]thio...)
Affinity DataEC50: >1.00E+4nMAssay Description:Inhibition of ROCK1 in human GTM3 cells by impedance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Kalypsys

Curated by ChEMBL
LigandPNGBDBM50319023(CHEMBL1084792 | methyl 3-((2-(2-aminopyrimidin-4-y...)
Affinity DataEC50: >1.00E+4nMAssay Description:Inhibition of ROCK1 in human GTM3 cells by impedance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed