Compile Data Set for Download or QSAR
Report error Found 10 of ic50 for UniProtKB: Q15059
TargetBromodomain-containing protein 3 [34-140](Human)
Nuvation Bio

US Patent
LigandPNGBDBM528580(US11192900, Compound 3 | US11192900, Example S-10)
Affinity DataIC50: 35nMAssay Description:The bromodomain binding assays were performed by Reaction Biology Corp., Malvern, Pa., USA (www.reactionbiology.com). The BET binding assays were con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2022
Entry Details
US Patent

TargetBromodomain-containing protein 3 [34-140](Human)
Nuvation Bio

US Patent
LigandPNGBDBM756831(US20250221977, Example 4 | US20250221977, Compound...)
Affinity DataIC50: 2.97E+4nMAssay Description:The binding inhibitory effect of the compounds of the present invention on the BRD3 protein among the BET proteins was tested as follows and confirme...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/26/2025
Entry Details
US Patent

TargetBromodomain-containing protein 3 [34-140](Human)
Nuvation Bio

US Patent
LigandPNGBDBM756827(US20250221977, Example 2 | US20250221977, Compound...)
Affinity DataIC50: 3.58E+4nMAssay Description:The binding inhibitory effect of the compounds of the present invention on the BRD3 protein among the BET proteins was tested as follows and confirme...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/26/2025
Entry Details
US Patent

TargetBromodomain-containing protein 3 [34-140](Human)
Nuvation Bio

US Patent
LigandPNGBDBM756821(US20250221977, Example 1 | US20250221977, Compound...)
Affinity DataIC50: 4.90E+4nMAssay Description:The binding inhibitory effect of the compounds of the present invention on the BRD3 protein among the BET proteins was tested as follows and confirme...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/26/2025
Entry Details
US Patent

TargetBromodomain-containing protein 3 [34-140](Human)
Nuvation Bio

US Patent
LigandPNGBDBM756832(US20250221977, Example 5 | US20250221977, Compound...)
Affinity DataIC50: 5.15E+4nMAssay Description:The binding inhibitory effect of the compounds of the present invention on the BRD3 protein among the BET proteins was tested as follows and confirme...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/26/2025
Entry Details
US Patent

TargetBromodomain-containing protein 3 [34-140](Human)
Nuvation Bio

US Patent
LigandPNGBDBM756830(US20250221977, Example 3 | US20250221977, Compound...)
Affinity DataIC50: 6.11E+4nMAssay Description:The binding inhibitory effect of the compounds of the present invention on the BRD3 protein among the BET proteins was tested as follows and confirme...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/26/2025
Entry Details
US Patent

TargetBromodomain-containing protein 3 [34-140](Human)
Nuvation Bio

US Patent
LigandPNGBDBM756834(US20250221977, Example 7 | US20250221977, Compound...)
Affinity DataIC50: 8.48E+4nMAssay Description:The binding inhibitory effect of the compounds of the present invention on the BRD3 protein among the BET proteins was tested as follows and confirme...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/26/2025
Entry Details
US Patent

TargetBromodomain-containing protein 3 [34-140](Human)
Nuvation Bio

US Patent
LigandPNGBDBM756833(US20250221977, Example 6 | US20250221977, Compound...)
Affinity DataIC50: 9.87E+4nMAssay Description:The binding inhibitory effect of the compounds of the present invention on the BRD3 protein among the BET proteins was tested as follows and confirme...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/26/2025
Entry Details
US Patent

TargetBromodomain-containing protein 3 [34-140](Human)
Nuvation Bio

US Patent
LigandPNGBDBM50365262(CHEMBL1957266 | (S)-JQ1 (1) | US9320741, (S)-JQ1 |...)
Affinity DataIC50: 2.61E+5nMAssay Description:The binding inhibitory effect of the compounds of the present invention on the BRD3 protein among the BET proteins was tested as follows and confirme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2025
Entry Details
US Patent

TargetBromodomain-containing protein 3 [34-140](Human)
Nuvation Bio

US Patent
LigandPNGBDBM50103503(CHEMBL2393130 | US11117865, Compound RVX-208 | US2...)
Affinity DataIC50: 2.34E+7nMAssay Description:The binding inhibitory effect of the compounds of the present invention on the BRD3 protein among the BET proteins was tested as follows and confirme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2025
Entry Details
US Patent