Compile Data Set for Download or QSAR
Report error Found 14 of ki for UniProtKB: P06213
TargetInsulin receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50256480(N-(2,6-difluorophenyl)-5-(3-(2-(5-ethyl-2-methoxy-...)
Affinity DataKi:  1.30nMAssay Description:Binding affinity to insulin receptor by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetInsulin receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50256480(N-(2,6-difluorophenyl)-5-(3-(2-(5-ethyl-2-methoxy-...)
Affinity DataKi:  1.30nMAssay Description:Inhibition of intracellular domain of GST-tagged IR (979 to 1382 residues) (unknown origin) expressed in baculovirus expression system using biotin-a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
TargetInsulin receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50256478(N-(2,6-difluorophenyl)-3-(3-(2-(2-methoxy-4-(4-(4-...)
Affinity DataKi:  2.20nMAssay Description:Binding affinity to insulin receptor by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetInsulin receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50341519((S)-3-(4-(2-(pyrrolidin-1-ylmethyl)pyrrolidin-1-yl...)
Affinity DataKi: >1.00E+3nMAssay Description:Inhibition of IRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetInsulin receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50463479(CHEMBL4249925)
Affinity DataKi: >2.00E+3nMAssay Description:Inhibition of INSR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetInsulin receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50463483(CHEMBL4245242)
Affinity DataKi: >2.00E+3nMAssay Description:Inhibition of INSR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetInsulin receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM15236(CHEMBL164 | Cannabiscetin | 3,5,7-trihydroxy-2-(3,...)
Affinity DataKi:  2.60E+3nMAssay Description:Inhibition of insulin receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetInsulin receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50237710(AMN 107 | AMN107 | 4-methyl-N-[3-(4-methyl-1H-imid...)
Affinity DataKi:  4.10E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2012
Entry Details Article
PubMed
TargetInsulin receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50224883(7-chloro-3-oxo-8-[(thiazol-5-ylmethyl)-amino]-11,1...)
Affinity DataKi: >5.24E+3nMAssay Description:Inhibition of INSRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetInsulin receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50181669(5-benzo[1,3]dioxol-5-yl-2-oxo-1,2-dihydro-pyridine...)
Affinity DataKi:  5.30E+3nMAssay Description:Inhibitory activity against IRKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInsulin receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50181670(5-benzo[1,3]dioxol-5-yl-2-oxo-1,2-dihydro-pyridine...)
Affinity DataKi:  8.80E+3nMAssay Description:Inhibitory activity against IRKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInsulin receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50181675(5-benzo[1,3]dioxol-5-yl-2-oxo-1,2-dihydro-pyridine...)
Affinity DataKi:  9.00E+3nMAssay Description:Inhibitory activity against IRKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInsulin receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM13530(cid_5291 | STI571 | N-(4-methyl-3-{[4-(pyridin-3-y...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2012
Entry Details Article
PubMed
TargetInsulin receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50011995(CHEMBL26001 | hydroxy(naphthalen-2-yl)methylphosph...)
Affinity DataKi:  9.50E+4nMAssay Description:Non-competitive inhibition of human placental insulin receptor expressed in CHO cell membrane assessed as decrease in insulin-stimulated A2 phosphory...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed