Compile Data Set for Download or QSAR
Report error Found 545 of ki data for polymerid = 1260
TargetCollagenase 3(Human)
Paris-Saclay University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50259948BDBM50259948(CHEMBL4096462)
Affinity DataKi:  0.00800nMAssay Description:Inhibition of human MMP13 catalytic domain using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 fluorogenic substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2020
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Paris-Saclay University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50082556BDBM50082556(AG-3340 | 2,2-Dimethyl-4-[4-(pyridin-4-yloxy)-benz...)
Affinity DataKi:  0.0380nMAssay Description:Inhibition of collagenase (Matrix metalloprotease-13)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2012
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Paris-Saclay University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50082556BDBM50082556(AG-3340 | 2,2-Dimethyl-4-[4-(pyridin-4-yloxy)-benz...)
Affinity DataKi:  0.0380nMAssay Description:Inhibition of matrix metalloprotease-13 (MMP-13).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Paris-Saclay University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 11873BDBM11873(N-hydroxy-1-methyl-4-[(4-phenoxybenzene)sulfonyl]p...)
Affinity DataKi:  0.100nMAssay Description:Inhibitors were assayed against purified hMMP-1, hMMP-2, hMMP-3, hMMP-8, hMMP-9, and hMMP-13 using an enzyme assay based on cleavage of the quenched ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2006
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Paris-Saclay University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 11874BDBM11874(N-hydroxy-1-(2-methoxyethyl)-4-[(4-phenoxybenzene)...)
Affinity DataKi:  0.100nMAssay Description:Inhibitors were assayed against purified hMMP-1, hMMP-2, hMMP-3, hMMP-8, hMMP-9, and hMMP-13 using an enzyme assay based on cleavage of the quenched ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2006
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Paris-Saclay University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 11876BDBM11876(1-(Cyclopropylmethyl)-N-hydroxy-4-[(4-phenoxypheny...)
Affinity DataKi: <0.100nMAssay Description:Inhibitors were assayed against purified hMMP-1, hMMP-2, hMMP-3, hMMP-8, hMMP-9, and hMMP-13 using an enzyme assay based on cleavage of the quenched ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2006
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Paris-Saclay University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 11878BDBM11878(1-Acetyl-N-hydroxy-4-{[4-(phenoxyphenyl]sulfonyl}-...)
Affinity DataKi: <0.100nMAssay Description:Inhibitors were assayed against purified hMMP-1, hMMP-2, hMMP-3, hMMP-8, hMMP-9, and hMMP-13 using an enzyme assay based on cleavage of the quenched ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2006
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Paris-Saclay University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343081BDBM50343081(N-hydroxy-1-(2-methoxyethyl)-4-(4-(3-(5-(4-(triflu...)
Affinity DataKi:  0.130nMAssay Description:Inhibition of human MMP-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Paris-Saclay University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 11870BDBM11870(4-{[4-(4-chlorophenoxy)benzene]sulfonyl}-N-hydroxy...)
Affinity DataKi:  0.150nMAssay Description:Inhibitors were assayed against purified hMMP-1, hMMP-2, hMMP-3, hMMP-8, hMMP-9, and hMMP-13 using an enzyme assay based on cleavage of the quenched ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2006
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Paris-Saclay University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50305851BDBM50305851(trans-4-((5-(2-(3-methoxybenzylcarbamoyl)-6-methyl...)
Affinity DataKi:  0.160nMAssay Description:Inhibition of full length human recombinant MMP13 using MCA-Arg-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-Glu-Arg-NH2 as substrate preincubated for 60 mins followe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2017
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Paris-Saclay University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50305851BDBM50305851(trans-4-((5-(2-(3-methoxybenzylcarbamoyl)-6-methyl...)
Affinity DataKi:  0.160nMAssay Description:Inhibition of human recombinant full length MMP13 assessed as type 3 collagen cleavage activity after 18 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Paris-Saclay University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50305844BDBM50305844(4-((5-(2-(3-methoxybenzylcarbamoyl)-6-methylpyridi...)
Affinity DataKi:  0.180nMAssay Description:Inhibition of human recombinant full length MMP13 assessed as type 3 collagen cleavage activity after 18 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Paris-Saclay University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 30369BDBM30369(piperidinyl glycine derivative, 24f)
Affinity DataKi:  0.190nM ΔG°:  -13.1kcal/mole IC50: 0.5nMpH: 7.5 T: 2°CAssay Description:Test compounds were serially diluted in the assay buffer. In each well of a 96-well microtiter plate (Immunofluor B, Dynatech), the inhibitor solutio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Paris-Saclay University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 11883BDBM11883(1-Cyclopropyl-N-hydroxy-4-{[4-(phenylthio)phenyl]-...)
Affinity DataKi:  0.200nMAssay Description:Inhibitors were assayed against purified hMMP-1, hMMP-2, hMMP-3, hMMP-8, hMMP-9, and hMMP-13 using an enzyme assay based on cleavage of the quenched ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2006
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Paris-Saclay University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50142473BDBM50142473(CHEMBL3758194)
Affinity DataKi:  0.200nMAssay Description:Inhibition of full length human recombinant MMP13 using MCA-Arg-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-Glu-Arg-NH2 as substrate preincubated for 60 mins followe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2017
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Paris-Saclay University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 11864BDBM11864(tert-Butyl 4-[(Hydroxyamino)carbonyl]-4-{[(4-pheno...)
Affinity DataKi:  0.200nMAssay Description:Inhibitors were assayed against purified hMMP-1, hMMP-2, hMMP-3, hMMP-8, hMMP-9, and hMMP-13 using an enzyme assay based on cleavage of the quenched ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2006
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Paris-Saclay University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50305858BDBM50305858(trans-4-((5-(2-(4-fluoro-3-methylbenzylcarbamoyl)-...)
Affinity DataKi:  0.220nMAssay Description:Inhibition of human recombinant full length MMP13 assessed as type 3 collagen cleavage activity after 18 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Paris-Saclay University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 11877BDBM11877(N-Hydroxy-4-{[4-(phenoxyphenyl]sulfonyl}-1- (2-pro...)
Affinity DataKi:  0.220nMAssay Description:Inhibitors were assayed against purified hMMP-1, hMMP-2, hMMP-3, hMMP-8, hMMP-9, and hMMP-13 using an enzyme assay based on cleavage of the quenched ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2006
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Paris-Saclay University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 11889BDBM11889(N-hydroxy-2-methyl-2-[(4-phenoxybenzene)sulfonyl]p...)
Affinity DataKi:  0.25nMAssay Description:Inhibitors were assayed against purified hMMP-1, hMMP-2, hMMP-3, hMMP-8, hMMP-9, and hMMP-13 using an enzyme assay based on cleavage of the quenched ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2006
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Paris-Saclay University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50142443BDBM50142443(CHEMBL3758625)
Affinity DataKi:  0.25nMAssay Description:Inhibition of full length human recombinant MMP13 using MCA-Arg-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-Glu-Arg-NH2 as substrate preincubated for 60 mins followe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2017
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Paris-Saclay University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50305856BDBM50305856(trans-4-((5-(2-(3-chloro-4-fluorobenzylcarbamoyl)-...)
Affinity DataKi:  0.260nMAssay Description:Inhibition of human recombinant full length MMP13 assessed as type 3 collagen cleavage activity after 18 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Paris-Saclay University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 11863BDBM11863(CHEMBL440498 | alpha-tetrahydropyran beta-sulfone ...)
Affinity DataKi:  0.280nM ΔG°:  -12.9kcal/mole IC50: 0.300nMpH: 7.5 T: 2°CAssay Description:Test compounds were serially diluted in the assay buffer. In each well of a 96-well microtiter plate (Immunofluor B, Dynatech), the inhibitor solutio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCollagenase 3(Human)
Paris-Saclay University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 11884BDBM11884(N-hydroxy-4-{[4-(phenylsulfanyl)benzene]sulfonyl}-...)
Affinity DataKi:  0.300nMAssay Description:Inhibitors were assayed against purified hMMP-1, hMMP-2, hMMP-3, hMMP-8, hMMP-9, and hMMP-13 using an enzyme assay based on cleavage of the quenched ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2006
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Paris-Saclay University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 11871BDBM11871(tert-butyl 4-(hydroxycarbamoyl)-4-[(4-phenoxybenze...)
Affinity DataKi:  0.300nMAssay Description:Inhibitors were assayed against purified hMMP-1, hMMP-2, hMMP-3, hMMP-8, hMMP-9, and hMMP-13 using an enzyme assay based on cleavage of the quenched ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2006
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Paris-Saclay University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 11875BDBM11875(1-cyclopropyl-N-hydroxy-4-[(4-phenoxybenzene)sulfo...)
Affinity DataKi:  0.300nMAssay Description:Inhibitors were assayed against purified hMMP-1, hMMP-2, hMMP-3, hMMP-8, hMMP-9, and hMMP-13 using an enzyme assay based on cleavage of the quenched ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2006
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Paris-Saclay University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50305855BDBM50305855(trans-4-((5-(2-(4-fluoro-3-methoxybenzylcarbamoyl)...)
Affinity DataKi:  0.300nMAssay Description:Inhibition of human recombinant full length MMP13 assessed as type 3 collagen cleavage activity after 18 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Paris-Saclay University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50160843BDBM50160843(1-[4-(4-Phenoxy-phenoxy)-phenyl]-1,7,9-triaza-spir...)
Affinity DataKi:  0.330nMAssay Description:Inhibition of matrix metalloprotease-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Paris-Saclay University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50160843BDBM50160843(1-[4-(4-Phenoxy-phenoxy)-phenyl]-1,7,9-triaza-spir...)
Affinity DataKi:  0.331nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Paris-Saclay University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 11872BDBM11872(N-hydroxy-4-[(4-phenoxybenzene)sulfonyl]piperidine...)
Affinity DataKi:  0.370nMAssay Description:Inhibitors were assayed against purified hMMP-1, hMMP-2, hMMP-3, hMMP-8, hMMP-9, and hMMP-13 using an enzyme assay based on cleavage of the quenched ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2006
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Paris-Saclay University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 11885BDBM11885(N-hydroxy-4-{[4-(phenylsulfanyl)benzene]sulfonyl}-...)
Affinity DataKi:  0.400nMAssay Description:Inhibitors were assayed against purified hMMP-1, hMMP-2, hMMP-3, hMMP-8, hMMP-9, and hMMP-13 using an enzyme assay based on cleavage of the quenched ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2006
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Paris-Saclay University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 11866BDBM11866(N-hydroxy-1-[(3-methoxyphenyl)methyl]-4-{[(4-pheno...)
Affinity DataKi:  0.400nMAssay Description:Inhibitors were assayed against purified hMMP-1, hMMP-2, hMMP-3, hMMP-8, hMMP-9, and hMMP-13 using an enzyme assay based on cleavage of the quenched ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2006
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Paris-Saclay University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50102594BDBM50102594(7-Isobutyl-8-oxo-2-oxa-9-aza-bicyclo[10.2.2]hexade...)
Affinity DataKi:  0.450nMAssay Description:Inhibition of matrix metalloprotease-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Paris-Saclay University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50268316BDBM50268316(CHEMBL4080186)
Affinity DataKi:  0.470nMAssay Description:Inhibition of human recombinant MMP-13 catalytic domain (104 to 274 residues) expressed in Escherichia coli using fluorogenic Mca-KPLGL-Dpa-AR-NH2 as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2020
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Paris-Saclay University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 11879BDBM11879(N-hydroxy-1-methanesulfonyl-4-[(4-phenoxybenzene)s...)
Affinity DataKi:  0.5nMAssay Description:Inhibitors were assayed against purified hMMP-1, hMMP-2, hMMP-3, hMMP-8, hMMP-9, and hMMP-13 using an enzyme assay based on cleavage of the quenched ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2006
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Paris-Saclay University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50183784BDBM50183784(N*4*-(2,2-Dimethyl-1-methylcarbamoyl-propyl)-N*1*-...)
Affinity DataKi:  0.5nMAssay Description:Binding affinity to recombinant MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Paris-Saclay University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 11882BDBM11882(N-hydroxy-1-(2-methoxyethyl)-4-{[4-(phenylsulfanyl...)
Affinity DataKi:  0.5nMAssay Description:Inhibitors were assayed against purified hMMP-1, hMMP-2, hMMP-3, hMMP-8, hMMP-9, and hMMP-13 using an enzyme assay based on cleavage of the quenched ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2006
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Paris-Saclay University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 11863BDBM11863(CHEMBL440498 | alpha-tetrahydropyran beta-sulfone ...)
Affinity DataKi:  0.520nMAssay Description:Inhibition of matrix metalloprotease-13 (MMP-13).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCollagenase 3(Human)
Paris-Saclay University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 11870BDBM11870(4-{[4-(4-chlorophenoxy)benzene]sulfonyl}-N-hydroxy...)
Affinity DataKi:  0.520nMAssay Description:Inhibition of MMP-13 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetCollagenase 3(Human)
Paris-Saclay University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 11863BDBM11863(CHEMBL440498 | alpha-tetrahydropyran beta-sulfone ...)
Affinity DataKi:  0.520nMAssay Description:Binding affinity for matrix metalloprotease 13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCollagenase 3(Human)
Paris-Saclay University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 30344BDBM30344(Trocade | Cipemastat)
Affinity DataKi:  0.530nM ΔG°:  -12.5kcal/mole IC50: 3.5nMpH: 7.5 T: 2°CAssay Description:Test compounds were serially diluted in the assay buffer. In each well of a 96-well microtiter plate (Immunofluor B, Dynatech), the inhibitor solutio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Paris-Saclay University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50160852BDBM50160852(4-ethyl-1-(4-phenoxy-phenyl)-1,7,9-triaza-spiro[4....)
Affinity DataKi:  0.540nMAssay Description:Binding affinity for matrix metalloprotease 13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Paris-Saclay University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50160852BDBM50160852(4-ethyl-1-(4-phenoxy-phenyl)-1,7,9-triaza-spiro[4....)
Affinity DataKi:  0.540nMAssay Description:Binding affinity for matrix metalloprotease 13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Paris-Saclay University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 11868BDBM11868(CHEMBL256157 | N-hydroxy-4-{[(4-phenoxybenzene)sul...)
Affinity DataKi:  0.550nMAssay Description:Inhibitors were assayed against purified hMMP-1, hMMP-2, hMMP-3, hMMP-8, hMMP-9, and hMMP-13 using an enzyme assay based on cleavage of the quenched ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2006
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Paris-Saclay University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50268309BDBM50268309(CHEMBL4088060)
Affinity DataKi:  0.590nMAssay Description:Inhibition of human recombinant MMP-13 catalytic domain (104 to 274 residues) expressed in Escherichia coli using fluorogenic Mca-KPLGL-Dpa-AR-NH2 as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2020
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Paris-Saclay University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 11886BDBM11886(1-acetyl-N-hydroxy-4-{[4-(phenylsulfanyl)benzene]s...)
Affinity DataKi:  0.600nMAssay Description:Inhibitors were assayed against purified hMMP-1, hMMP-2, hMMP-3, hMMP-8, hMMP-9, and hMMP-13 using an enzyme assay based on cleavage of the quenched ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2006
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Paris-Saclay University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343083BDBM50343083(N-hydroxy-4-(4-(3-(5-(5-methylpyridin-2-yl)-1H-tet...)
Affinity DataKi:  0.600nMAssay Description:Inhibition of human MMP-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Paris-Saclay University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 11863BDBM11863(CHEMBL440498 | alpha-tetrahydropyran beta-sulfone ...)
Affinity DataKi:  0.600nMAssay Description:Inhibitors were assayed against purified hMMP-1, hMMP-2, hMMP-3, hMMP-8, hMMP-9, and hMMP-13 using an enzyme assay based on cleavage of the quenched ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2006
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCollagenase 3(Human)
Paris-Saclay University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50305857BDBM50305857(trans-4-((5-(2-(4-fluoro-3-(trifluoromethyl)benzyl...)
Affinity DataKi:  0.620nMAssay Description:Inhibition of human recombinant full length MMP13 assessed as type 3 collagen cleavage activity after 18 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Paris-Saclay University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343082BDBM50343082(N-hydroxy-4-(4-(3-(5-(5-methylpyridin-2-yl)-2H-tet...)
Affinity DataKi:  0.660nMAssay Description:Inhibition of human MMP-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Paris-Saclay University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50343080BDBM50343080(N-hydroxy-4-(4-(3-(5-(4-(trifluoromethoxy)phenyl)-...)
Affinity DataKi:  0.660nMAssay Description:Inhibition of human MMP-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
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