Affinity DataIC50: 1nMAssay Description:Inhibition of amino terminally biotinylated E-76 peptide binding to immobilized fVIIaMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of amino terminally biotinylated E-76 peptide binding to immobilized fVIIaMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Inhibition of amino terminally biotinylated E-76 peptide binding to immobilized fVIIaMore data for this Ligand-Target Pair
TargetCoagulation factor VII/Tissue factor(Homo sapiens (Human))
Laboratory Of Molecular Biology, Medical Research Council
Curated by ChEMBL
Laboratory Of Molecular Biology, Medical Research Council
Curated by ChEMBL
Affinity DataIC50: 1.5nMAssay Description:Binding affinity to tissue factor/factor 7aMore data for this Ligand-Target Pair
Affinity DataIC50: 1.60nMAssay Description:Inhibition of amino terminally biotinylated E-76 peptide binding to immobilized fVIIaMore data for this Ligand-Target Pair
Affinity DataIC50: 1.70nMAssay Description:Inhibitory concentration against Coagulation factor VIIaMore data for this Ligand-Target Pair
Affinity DataIC50: 1.80nMAssay Description:Inhibition of amino terminally biotinylated E-76 peptide binding to immobilized fVIIaMore data for this Ligand-Target Pair
Affinity DataIC50: 1.90nMAssay Description:Inhibitory activity for the compound against coagulation factor VIIa in presence of 1% rabbit serum albuminMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibitory activity for the compound against coagulation factor VIIa in presence of 1% rabbit serum albuminMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibitory activity for the compound against coagulation factor VIIa in presence of 1% human serum albuminMore data for this Ligand-Target Pair
Affinity DataIC50: 2.40nMAssay Description:Inhibitory activity for the compound against coagulation factor VIIa in presence of 1% human serum albuminMore data for this Ligand-Target Pair
Affinity DataIC50: 2.5nMAssay Description:Inhibitory activity for the compound against coagulation factor VIIa in presence of 1% human serum albuminMore data for this Ligand-Target Pair
Affinity DataIC50: 2.90nMAssay Description:Inhibition of amino terminally biotinylated E-76 peptide binding to immobilized fVIIaMore data for this Ligand-Target Pair
Affinity DataIC50: 3.40nMAssay Description:Inhibitory activity for the compound against coagulation factor VIIa in presence of 1% rabbit serum albuminMore data for this Ligand-Target Pair
Affinity DataIC50: 3.60nMAssay Description:Inhibitory activity for the compound against coagulation factor VIIa in presence of 1% rabbit serum albuminMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of amino terminally biotinylated E-76 peptide binding to immobilized fVIIaMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibitory activity for the compound against coagulation factor VIIa in presence of 1% ovalbuminMore data for this Ligand-Target Pair
Affinity DataIC50: 4.70nMAssay Description:Inhibition of human factor 7a preincubated for 30 mins followed by substrate addition and measured for 20 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of human F7a using D-Ile-Pro-Arg-AFC as substrate after 3 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 6.20nMAssay Description:Inhibitory concentration against Coagulation factor VIIaMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibition of human F7a using D-Ile-Pro-Arg-AFC as substrate after 3 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMT: 2°CAssay Description:TF-FVIIa assay reactions were performed in a mixture containing FVIIa , lapidated tissue factor, in an assay buffer in the presence of test compounds...More data for this Ligand-Target Pair
TargetCoagulation factor VII/Tissue factor(Homo sapiens (Human))
Laboratory Of Molecular Biology, Medical Research Council
Curated by ChEMBL
Laboratory Of Molecular Biology, Medical Research Council
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Inhibitory concentration against human coagulation factor VIIa/tissue factor cleavage of fluorogenic substrate SN17c at 37 degree C for 15 minutesMore data for this Ligand-Target Pair
Affinity DataIC50: 9nMpH: 7.2 T: 2°CAssay Description:TF-FVIIa assay reactions were performed in a mixture containing FVIIa , lapidated tissue factor, in an assay buffer in the presence of test compounds...More data for this Ligand-Target Pair
Affinity DataIC50: 9nMT: 2°CAssay Description:TF-FVIIa assay reactions were performed in a mixture containing FVIIa , lapidated tissue factor, in an assay buffer in the presence of test compounds...More data for this Ligand-Target Pair
Affinity DataIC50: 9nMT: 2°CAssay Description:TF-FVIIa assay reactions were performed in a mixture containing FVIIa , lapidated tissue factor, in an assay buffer in the presence of test compounds...More data for this Ligand-Target Pair
Affinity DataIC50: 9nMpH: 7.2 T: 2°CAssay Description:TF-FVIIa assay reactions were performed in a mixture containing FVIIa , lapidated tissue factor, in an assay buffer in the presence of test compounds...More data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inhibition of human F7a using D-Ile-Pro-Arg-AFC as substrate after 3 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 9nMpH: 7.2 T: 2°CAssay Description:TF-FVIIa assay reactions were performed in a mixture containing FVIIa , lapidated tissue factor, in an assay buffer in the presence of test compounds...More data for this Ligand-Target Pair
Affinity DataIC50: 9.20nMAssay Description:Inhibitory activity for the compound against coagulation factor VIIa in presence of 1% rabbit serum albuminMore data for this Ligand-Target Pair
Affinity DataIC50: 9.20nMAssay Description:Inhibitory activity for the compound against coagulation factor VIIa in presence of 1% rabbit serum albuminMore data for this Ligand-Target Pair
Affinity DataIC50: 9.40nMAssay Description:Inhibitory concentration against Coagulation factor VIIaMore data for this Ligand-Target Pair
Affinity DataIC50: 9.70nMAssay Description:Inhibitory activity for the compound against coagulation factor VIIa in presence of 1% ovalbuminMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of amino terminally biotinylated E-76 peptide binding to immobilized fVIIaMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMpH: 7.2 T: 2°CAssay Description:TF-FVIIa assay reactions were performed in a mixture containing FVIIa , lapidated tissue factor, in an assay buffer in the presence of test compounds...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMpH: 7.2 T: 2°CAssay Description:TF-FVIIa assay reactions were performed in a mixture containing FVIIa , lapidated tissue factor, in an assay buffer in the presence of test compounds...More data for this Ligand-Target Pair
TargetCoagulation factor VII/Tissue factor(Homo sapiens (Human))
Laboratory Of Molecular Biology, Medical Research Council
Curated by ChEMBL
Laboratory Of Molecular Biology, Medical Research Council
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibitory concentration against human coagulation factor VIIa/tissue factor cleavage of fluorogenic substrate SN17c at 37 degree C for 15 minutesMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of human factor 7a preincubated for 30 mins followed by substrate addition and measured for 20 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibitory activity for the compound against coagulation factor VIIa in presence of 1% human serum albuminMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of human F7a using D-Ile-Pro-Arg-AFC as substrate after 3 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMT: 2°CAssay Description:TF-FVIIa assay reactions were performed in a mixture containing FVIIa , lapidated tissue factor, in an assay buffer in the presence of test compounds...More data for this Ligand-Target Pair
Affinity DataIC50: 11nMpH: 7.2 T: 2°CAssay Description:TF-FVIIa assay reactions were performed in a mixture containing FVIIa , lapidated tissue factor, in an assay buffer in the presence of test compounds...More data for this Ligand-Target Pair
Affinity DataIC50: 11nMT: 2°CAssay Description:TF-FVIIa assay reactions were performed in a mixture containing FVIIa , lapidated tissue factor, in an assay buffer in the presence of test compounds...More data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of human F7a using D-Ile-Pro-Arg-AFC as substrate after 3 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibition of human factor 7a preincubated for 30 mins followed by substrate addition and measured for 20 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMpH: 7.2 T: 2°CAssay Description:TF-FVIIa assay reactions were performed in a mixture containing FVIIa , lapidated tissue factor, in an assay buffer in the presence of test compounds...More data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibitory concentration against Coagulation factor VIIaMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibition of amino terminally biotinylated E-76 peptide binding to immobilized fVIIaMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of amino terminally biotinylated E-76 peptide binding to immobilized fVIIaMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of amino terminally biotinylated E-76 peptide binding to immobilized fVIIaMore data for this Ligand-Target Pair