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Report error Found 2098 of ki for UniProtKB: P07477
TargetTrypsin(Human)
The University of Queensland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50507483BDBM50507483(CHEMBL4530379)
Affinity DataKi:  0.00230nMAssay Description:Inhibition of trypsin (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetTrypsin(Human)
The University of Queensland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50125046BDBM50125046(CHEMBL3623792)
Affinity DataKi:  0.0300nMAssay Description:Inhibition of beta-trypsin (unknown origin) using Bz-FVRpNA substrate by spectrophotometry methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2016
Entry Details Article
PubMed
TargetSerine protease 1(Human)
The University of Queensland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50124947BDBM50124947(CHEMBL453539)
Affinity DataKi:  0.0300nMAssay Description:Inhibition of human cationic trypsin using Boc-VPR-MCA as substrate measured every 30 secs for 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetSerine protease 1(Human)
The University of Queensland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50288406BDBM50288406(1-(2-Acetylamino-3-phenyl-propionyl)-pyrrolidine-2...)
Affinity DataKi:  0.0450nMAssay Description:Inhibition of trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetSerine protease 1(Human)
The University of Queensland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50288406BDBM50288406(1-(2-Acetylamino-3-phenyl-propionyl)-pyrrolidine-2...)
Affinity DataKi:  0.0450nMAssay Description:Compound was tested in vitro for inhibition of trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetSerine protease 1(Human)
The University of Queensland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50069922BDBM50069922(Boropeptide analogue | CHEMBL102069)
Affinity DataKi:  0.0450nMAssay Description:Tested for selectivity against trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2012
Entry Details Article

TargetSerine protease 1(Human)
The University of Queensland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 109663BDBM109663(US8609715, A-71)
Affinity DataKi:  0.0540nMAssay Description:Inhibition assay using human trysin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2014
Entry Details
US Patent

TargetSerine protease 1(Human)
The University of Queensland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 234238BDBM234238(US9346821, A-6)
Affinity DataKi:  0.0800nMpH: 8.0Assay Description:Using a 96 well plate (#3915, Costar), a test compound (25 μL), 400 mM Tris-HCl buffer (pH 8.0, 25 μL) and 0.5 mg/mL fluorescence enzyme su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetTrypsin(Human)
The University of Queensland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50124947BDBM50124947(CHEMBL453539)
Affinity DataKi:  0.100nMAssay Description:Inhibition of trypsin (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2016
Entry Details Article
PubMed
TargetTrypsin(Human)
The University of Queensland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50421510BDBM50421510(CHEMBL239127)
Affinity DataKi:  0.100nMAssay Description:Compound was tested for inhibition of Sunflower beta-trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
The University of Queensland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50289586BDBM50289586(3-Methyl-2'-sulfamoyl-biphenyl-4-carboxylic acid [...)
Affinity DataKi:  0.110nMAssay Description:Inhibition of trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetSerine protease 1(Human)
The University of Queensland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 109651BDBM109651(US8609715, A-59)
Affinity DataKi:  0.120nMAssay Description:Inhibition assay using human trysin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2014
Entry Details
US Patent

TargetSerine protease 1(Human)
The University of Queensland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 109630BDBM109630(US8609715, B-21)
Affinity DataKi:  0.150nMAssay Description:Inhibition assay using human trysin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2014
Entry Details
US Patent

TargetTrypsin(Human)
The University of Queensland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50125045BDBM50125045(CHEMBL3623793)
Affinity DataKi:  0.160nMAssay Description:Inhibition of beta-trypsin (unknown origin) using Bz-FVRpNA substrate by spectrophotometry methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2016
Entry Details Article
PubMed
TargetTrypsin(Human)
The University of Queensland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50533536BDBM50533536(CHEMBL4483694)
Affinity DataKi:  0.160nMAssay Description:Inhibition of trypsin (unknown origin) using Bz-FVRpNA as substrate incubated for 30 mins measured for 7 mins by morrison plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetSerine protease 1(Human)
The University of Queensland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 158146BDBM158146(US9024044, 74 | US9227949, 74 | US9655879, 74)
Affinity DataKi:  0.180nMAssay Description:Using a 96 well plate (#3915, Costar), a test compound (25 μL), 400 mM Tris-HCl buffer (pH 8.0, 25 μL) and 0.5 mg/mL fluorescence enzyme su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2019
Entry Details
US Patent

TargetSerine protease 1(Human)
The University of Queensland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 109692BDBM109692(US8609715, B-49)
Affinity DataKi:  0.180nMAssay Description:Inhibition assay using human trysin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2014
Entry Details
US Patent

TargetSerine protease 1(Human)
The University of Queensland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 158146BDBM158146(US9024044, 74 | US9227949, 74 | US9655879, 74)
Affinity DataKi:  0.180nMpH: 8.0Assay Description:Using a 96 well plate (#3915, Costar), a test compound (25 uL) was mixed with 20 uM fluorescence enzyme substrate (Boc-Phe-Ser-Arg-AMC, 50 uL) mixed ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2016
Entry Details
US Patent

TargetSerine protease 1(Human)
The University of Queensland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 109629BDBM109629(US8609715, B-20)
Affinity DataKi:  0.180nMAssay Description:Inhibition assay using human trysin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2014
Entry Details
US Patent

TargetSerine protease 1(Human)
The University of Queensland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 158146BDBM158146(US9024044, 74 | US9227949, 74 | US9655879, 74)
Affinity DataKi:  0.180nMpH: 8.0Assay Description:Using a 96 well plate (#3915, Costar), a test compound (25 μL) was mixed with 20 μM fluorescence enzyme substrate (Boc-Phe-Ser-Arg-AMC, 50 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2015
Entry Details
US Patent

TargetSerine protease 1(Human)
The University of Queensland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 109668BDBM109668(US8609715, B-25)
Affinity DataKi:  0.190nMAssay Description:Inhibition assay using human trysin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2014
Entry Details
US Patent

TargetSerine protease 1(Human)
The University of Queensland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 234247BDBM234247(US9346821, B-14)
Affinity DataKi:  0.190nMpH: 8.0Assay Description:Using a 96 well plate (#3915, Costar), a test compound (25 μL), 400 mM Tris-HCl buffer (pH 8.0, 25 μL) and 0.5 mg/mL fluorescence enzyme su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetSerine protease 1(Human)
The University of Queensland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 109659BDBM109659(US8609715, A-67)
Affinity DataKi:  0.200nMAssay Description:Inhibition assay using human trysin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2014
Entry Details
US Patent

TargetSerine protease 1(Human)
The University of Queensland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 109710BDBM109710(US8609715, C-4)
Affinity DataKi:  0.200nMAssay Description:Inhibition assay using human trysin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2014
Entry Details
US Patent

TargetSerine protease 1(Human)
The University of Queensland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 109684BDBM109684(US8609715, B-41)
Affinity DataKi:  0.210nMAssay Description:Inhibition assay using human trysin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2014
Entry Details
US Patent

TargetSerine protease 1(Human)
The University of Queensland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 158140BDBM158140(US9024044, 68 | US9227949, 68 | US9655879, 68)
Affinity DataKi:  0.210nMpH: 8.0Assay Description:Using a 96 well plate (#3915, Costar), a test compound (25 μL) was mixed with 20 μM fluorescence enzyme substrate (Boc-Phe-Ser-Arg-AMC, 50 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2015
Entry Details
US Patent

TargetSerine protease 1(Human)
The University of Queensland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 234250BDBM234250(US9346821, B-20)
Affinity DataKi:  0.210nMpH: 8.0Assay Description:Using a 96 well plate (#3915, Costar), a test compound (25 μL), 400 mM Tris-HCl buffer (pH 8.0, 25 μL) and 0.5 mg/mL fluorescence enzyme su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetSerine protease 1(Human)
The University of Queensland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 158140BDBM158140(US9024044, 68 | US9227949, 68 | US9655879, 68)
Affinity DataKi:  0.210nMpH: 8.0Assay Description:Using a 96 well plate (#3915, Costar), a test compound (25 uL) was mixed with 20 uM fluorescence enzyme substrate (Boc-Phe-Ser-Arg-AMC, 50 uL) mixed ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2016
Entry Details
US Patent

TargetSerine protease 1(Human)
The University of Queensland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 158140BDBM158140(US9024044, 68 | US9227949, 68 | US9655879, 68)
Affinity DataKi:  0.210nMAssay Description:Using a 96 well plate (#3915, Costar), a test compound (25 μL), 400 mM Tris-HCl buffer (pH 8.0, 25 μL) and 0.5 mg/mL fluorescence enzyme su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2019
Entry Details
US Patent

TargetSerine protease 1(Human)
The University of Queensland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 109685BDBM109685(US8609715, B-42)
Affinity DataKi:  0.220nMAssay Description:Inhibition assay using human trysin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2014
Entry Details
US Patent

TargetSerine protease 1(Human)
The University of Queensland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 109622BDBM109622(US8609715, B-8)
Affinity DataKi:  0.220nMAssay Description:Inhibition assay using human trysin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2014
Entry Details
US Patent

TargetSerine protease 1(Human)
The University of Queensland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 109660BDBM109660(US8609715, A-68)
Affinity DataKi:  0.230nMAssay Description:Inhibition assay using human trysin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2014
Entry Details
US Patent

TargetSerine protease 1(Human)
The University of Queensland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 234237BDBM234237(US9346821, A-5)
Affinity DataKi:  0.240nMpH: 8.0Assay Description:Using a 96 well plate (#3915, Costar), a test compound (25 μL), 400 mM Tris-HCl buffer (pH 8.0, 25 μL) and 0.5 mg/mL fluorescence enzyme su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetSerine protease 1(Human)
The University of Queensland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 234266BDBM234266(US9346821, B-55)
Affinity DataKi:  0.240nMpH: 8.0Assay Description:Using a 96 well plate (#3915, Costar), a test compound (25 μL), 400 mM Tris-HCl buffer (pH 8.0, 25 μL) and 0.5 mg/mL fluorescence enzyme su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetSerine protease 1(Human)
The University of Queensland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50088657BDBM50088657(N-(6-Amino-2-methyl-pyridin-3-ylmethyl)-2-((R)-3-i...)
Affinity DataKi:  0.240nMAssay Description:The compound was tested for its ability to inhibit thrombin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
The University of Queensland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 234243BDBM234243(US9346821, B-10)
Affinity DataKi:  0.25nMpH: 8.0Assay Description:Using a 96 well plate (#3915, Costar), a test compound (25 μL), 400 mM Tris-HCl buffer (pH 8.0, 25 μL) and 0.5 mg/mL fluorescence enzyme su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetSerine protease 1(Human)
The University of Queensland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 109700BDBM109700(US8609715, B-57)
Affinity DataKi:  0.270nMAssay Description:Inhibition assay using human trysin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2014
Entry Details
US Patent

TargetSerine protease 1(Human)
The University of Queensland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50088659BDBM50088659(N-(6-Amino-2-methyl-pyridin-3-ylmethyl)-2-(3,3-dii...)
Affinity DataKi:  0.270nMAssay Description:The compound was tested for its ability to inhibit thrombin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
The University of Queensland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50071570BDBM50071570(8-Isobutyl-2-(4-methoxy-phenyl)-1,3-dioxo-2,3,5,8-...)
Affinity DataKi:  0.280nMAssay Description:Compound was evaluated for its binding affinity to the trypsin enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
The University of Queensland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 234246BDBM234246(US9346821, B-13)
Affinity DataKi:  0.290nMpH: 8.0Assay Description:Using a 96 well plate (#3915, Costar), a test compound (25 μL), 400 mM Tris-HCl buffer (pH 8.0, 25 μL) and 0.5 mg/mL fluorescence enzyme su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetSerine protease 1/Trypsin-2(Human)
Lg Life Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50131780BDBM50131780((1-Benzhydryl-2-{2-[(5-carbamimidoyl-thiophen-2-yl...)
Affinity DataKi:  0.300nMAssay Description:In vitro inhibition constant (Ki) against human trypsin was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed
TargetSerine protease 1(Human)
The University of Queensland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 109662BDBM109662(US8609715, A-70)
Affinity DataKi:  0.300nMAssay Description:Inhibition assay using human trysin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2014
Entry Details
US Patent

TargetSerine protease 1(Human)
The University of Queensland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 109673BDBM109673(US8609715, B-30)
Affinity DataKi:  0.330nMAssay Description:Inhibition assay using human trysin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2014
Entry Details
US Patent

TargetSerine protease 1(Human)
The University of Queensland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 109691BDBM109691(US8609715, B-48)
Affinity DataKi:  0.370nMAssay Description:Inhibition assay using human trysin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2014
Entry Details
US Patent

TargetSerine protease 1(Human)
The University of Queensland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 234253BDBM234253(US9346821, B-26)
Affinity DataKi:  0.380nMpH: 8.0Assay Description:Using a 96 well plate (#3915, Costar), a test compound (25 μL), 400 mM Tris-HCl buffer (pH 8.0, 25 μL) and 0.5 mg/mL fluorescence enzyme su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetSerine protease 1(Human)
The University of Queensland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 234251BDBM234251(US9346821, B-21)
Affinity DataKi:  0.380nMpH: 8.0Assay Description:Using a 96 well plate (#3915, Costar), a test compound (25 μL), 400 mM Tris-HCl buffer (pH 8.0, 25 μL) and 0.5 mg/mL fluorescence enzyme su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetSerine protease 1(Human)
The University of Queensland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 109613BDBM109613(US8609715, A-35)
Affinity DataKi:  0.380nMAssay Description:Inhibition assay using human trysin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2014
Entry Details
US Patent

TargetSerine protease 1(Human)
The University of Queensland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 109631BDBM109631(US8609715, B-22)
Affinity DataKi:  0.390nMAssay Description:Inhibition assay using human trysin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2014
Entry Details
US Patent

TargetSerine protease 1(Human)
The University of Queensland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 109667BDBM109667(US8609715, C-2)
Affinity DataKi:  0.390nMAssay Description:Inhibition assay using human trysin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2014
Entry Details
US Patent

TargetSerine protease 1(Human)
The University of Queensland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 109705BDBM109705(US8609715, B-62)
Affinity DataKi:  0.400nMAssay Description:Inhibition assay using human trysin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2014
Entry Details
US Patent

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