TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
The University Of Notre Dame
Curated by ChEMBL
The University Of Notre Dame
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of FITC-GDA binding to human HSP90-beta incubated for 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
The University Of Notre Dame
Curated by ChEMBL
The University Of Notre Dame
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of HSP90-mediated Her2 degradation in human AU565 cells after 24 hrs by ELISAMore data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
The University Of Notre Dame
Curated by ChEMBL
The University Of Notre Dame
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of HSP90 in human A375 cells assessed as induction of HSP70 synthesis after 24 hrs by TRITC assayMore data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
The University Of Notre Dame
Curated by ChEMBL
The University Of Notre Dame
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of FITC-GDA binding to human HSP90-beta incubated for 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
The University Of Notre Dame
Curated by ChEMBL
The University Of Notre Dame
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Binding affinity to human recombinant HSP90More data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
The University Of Notre Dame
Curated by ChEMBL
The University Of Notre Dame
Curated by ChEMBL
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
The University Of Notre Dame
Curated by ChEMBL
The University Of Notre Dame
Curated by ChEMBL
Affinity DataIC50: 5.40nMAssay Description:Binding affinity to Hsp90 after 4 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
The University Of Notre Dame
Curated by ChEMBL
The University Of Notre Dame
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Inhibition of HSP90 in Huntington's disease patient derived fibroblasts assessed as reduction of mHtt level after 48 hrs by Western blot analysisMore data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
The University Of Notre Dame
Curated by ChEMBL
The University Of Notre Dame
Curated by ChEMBL
Affinity DataIC50: 6nM EC50: 40nMAssay Description:The assay is based upon displacement of a fluorescently labeled molecule, which binds specifically to the ATP-binding site of full-length human Hsp90...More data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
The University Of Notre Dame
Curated by ChEMBL
The University Of Notre Dame
Curated by ChEMBL
Affinity DataIC50: 6nM EC50: 6nMAssay Description:The assay is based upon displacement of a fluorescently labeled molecule, which binds specifically to the ATP-binding site of full-length human Hsp90...More data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
The University Of Notre Dame
Curated by ChEMBL
The University Of Notre Dame
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Inhibition of HSP90-mediated client protein HER2 degradationMore data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
The University Of Notre Dame
Curated by ChEMBL
The University Of Notre Dame
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Inhibition of HSP90-mediated client protein HER2 degradationMore data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
The University Of Notre Dame
Curated by ChEMBL
The University Of Notre Dame
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Inhibition of HSP90-mediated client protein HER2 degradationMore data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
The University Of Notre Dame
Curated by ChEMBL
The University Of Notre Dame
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Inhibition of HSP90 in Huntington's disease patient derived fibroblasts assessed as reduction of mHtt level after 48 hrs by Western blot analysisMore data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
The University Of Notre Dame
Curated by ChEMBL
The University Of Notre Dame
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Inhibition of HSP90-mediated client protein HER2 degradationMore data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
The University Of Notre Dame
Curated by ChEMBL
The University Of Notre Dame
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Inhibition of HSP90-mediated client protein HER2 degradationMore data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
The University Of Notre Dame
Curated by ChEMBL
The University Of Notre Dame
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Inhibition of HSP90-mediated client protein HER2 degradation in human MCF7 cellsMore data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
The University Of Notre Dame
Curated by ChEMBL
The University Of Notre Dame
Curated by ChEMBL
Affinity DataIC50: 7.40nMAssay Description:Binding affinity to Hsp90 after 4 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
The University Of Notre Dame
Curated by ChEMBL
The University Of Notre Dame
Curated by ChEMBL
Affinity DataIC50: 8nM EC50: 70nMAssay Description:The assay is based upon displacement of a fluorescently labeled molecule, which binds specifically to the ATP-binding site of full-length human Hsp90...More data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
The University Of Notre Dame
Curated by ChEMBL
The University Of Notre Dame
Curated by ChEMBL
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
The University Of Notre Dame
Curated by ChEMBL
The University Of Notre Dame
Curated by ChEMBL
Affinity DataIC50: 8.60nMAssay Description:Binding affinity to Hsp90 after 4 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
The University Of Notre Dame
Curated by ChEMBL
The University Of Notre Dame
Curated by ChEMBL
Affinity DataIC50: 8.80nMAssay Description:Binding affinity to Hsp90 after 4 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
The University Of Notre Dame
Curated by ChEMBL
The University Of Notre Dame
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Binding affinity to Hsp90 after 4 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
The University Of Notre Dame
Curated by ChEMBL
The University Of Notre Dame
Curated by ChEMBL
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
The University Of Notre Dame
Curated by ChEMBL
The University Of Notre Dame
Curated by ChEMBL
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
The University Of Notre Dame
Curated by ChEMBL
The University Of Notre Dame
Curated by ChEMBL
Affinity DataIC50: <10nMAssay Description:Inhibition of HSP90 in human MDA-kb2 cells assessed as reduction in glucocorticoid receptor-dependent luciferase expression after 18 hrs by firefly l...More data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
The University Of Notre Dame
Curated by ChEMBL
The University Of Notre Dame
Curated by ChEMBL
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
The University Of Notre Dame
Curated by ChEMBL
The University Of Notre Dame
Curated by ChEMBL
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
The University Of Notre Dame
Curated by ChEMBL
The University Of Notre Dame
Curated by ChEMBL
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
The University Of Notre Dame
Curated by ChEMBL
The University Of Notre Dame
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of HSP90-mediated pS6 phosphorylation in human A375 cells after 24 hrs by TRITC assayMore data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
The University Of Notre Dame
Curated by ChEMBL
The University Of Notre Dame
Curated by ChEMBL
Affinity DataIC50: 11nM EC50: 65nMAssay Description:The assay is based upon displacement of a fluorescently labeled molecule, which binds specifically to the ATP-binding site of full-length human Hsp90...More data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
The University Of Notre Dame
Curated by ChEMBL
The University Of Notre Dame
Curated by ChEMBL
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
The University Of Notre Dame
Curated by ChEMBL
The University Of Notre Dame
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of HSP90-mediated client protein HER2 degradation in human MCF7 cellsMore data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
The University Of Notre Dame
Curated by ChEMBL
The University Of Notre Dame
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of HSP90-mediated client protein HER2 degradation in human MCF7 cellsMore data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
The University Of Notre Dame
Curated by ChEMBL
The University Of Notre Dame
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Binding affinity to Hsp90 after 4 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
The University Of Notre Dame
Curated by ChEMBL
The University Of Notre Dame
Curated by ChEMBL
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
The University Of Notre Dame
Curated by ChEMBL
The University Of Notre Dame
Curated by ChEMBL
Affinity DataIC50: 12.6nMAssay Description:Binding affinity to Hsp90 after 4 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
The University Of Notre Dame
Curated by ChEMBL
The University Of Notre Dame
Curated by ChEMBL
Affinity DataIC50: 13nM EC50: 41nMAssay Description:The assay is based upon displacement of a fluorescently labeled molecule, which binds specifically to the ATP-binding site of full-length human Hsp90...More data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
The University Of Notre Dame
Curated by ChEMBL
The University Of Notre Dame
Curated by ChEMBL
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
The University Of Notre Dame
Curated by ChEMBL
The University Of Notre Dame
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of Hsp90 in human MCF7 cells assessed as Her2 degradationMore data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
The University Of Notre Dame
Curated by ChEMBL
The University Of Notre Dame
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Binding affinity to Hsp90 after 4 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
The University Of Notre Dame
Curated by ChEMBL
The University Of Notre Dame
Curated by ChEMBL
Affinity DataIC50: 14nM EC50: 114nMAssay Description:The assay is based upon displacement of a fluorescently labeled molecule, which binds specifically to the ATP-binding site of full-length human Hsp90...More data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
The University Of Notre Dame
Curated by ChEMBL
The University Of Notre Dame
Curated by ChEMBL
Affinity DataIC50: 14nM EC50: 86nMAssay Description:The assay is based upon displacement of a fluorescently labeled molecule, which binds specifically to the ATP-binding site of full-length human Hsp90...More data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
The University Of Notre Dame
Curated by ChEMBL
The University Of Notre Dame
Curated by ChEMBL
Affinity DataIC50: 14nM EC50: 1.98E+3nMpH: 7.4 T: 2°CAssay Description:The assay is based upon displacement of a fluorescently labeled molecule, which binds specifically to the ATP-binding site of full-length human Hsp90...More data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
The University Of Notre Dame
Curated by ChEMBL
The University Of Notre Dame
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Inhibition of Hsp90 in human MCF7 cells assessed as Her2 degradationMore data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
The University Of Notre Dame
Curated by ChEMBL
The University Of Notre Dame
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Binding affinity to Hsp90 after 4 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
The University Of Notre Dame
Curated by ChEMBL
The University Of Notre Dame
Curated by ChEMBL
Affinity DataIC50: 15nM EC50: 80nMAssay Description:The assay is based upon displacement of a fluorescently labeled molecule, which binds specifically to the ATP-binding site of full-length human Hsp90...More data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
The University Of Notre Dame
Curated by ChEMBL
The University Of Notre Dame
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Binding affinity to Hsp90 after 4 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
The University Of Notre Dame
Curated by ChEMBL
The University Of Notre Dame
Curated by ChEMBL
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
The University Of Notre Dame
Curated by ChEMBL
The University Of Notre Dame
Curated by ChEMBL