Compile Data Set for Download or QSAR
maximum 50k data
Found 879 of ic50 for UniProtKB: A0A024RD80
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
The University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50450704(CHEMBL560895 | SNX-2112)
Affinity DataIC50:  4nMAssay Description:Inhibition of FITC-GDA binding to human HSP90-beta incubated for 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
The University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50379853(CHEMBL2011854)
Affinity DataIC50:  4nMAssay Description:Inhibition of HSP90-mediated Her2 degradation in human AU565 cells after 24 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
The University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50379853(CHEMBL2011854)
Affinity DataIC50:  5nMAssay Description:Inhibition of HSP90 in human A375 cells assessed as induction of HSP70 synthesis after 24 hrs by TRITC assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
The University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50003868(CHEMBL3235353)
Affinity DataIC50:  5nMAssay Description:Inhibition of FITC-GDA binding to human HSP90-beta incubated for 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
The University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50249943(11-O-(Hydrzinocarbonyl)-17-[2-(dimethylamino)ethyl...)
Affinity DataIC50:  5nMAssay Description:Binding affinity to human recombinant HSP90More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
The University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM225747(hsp90_44)
Affinity DataIC50:  5.22nMAssay Description:FRET Assay 1More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
The University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50361691(CHEMBL1940934)
Affinity DataIC50:  5.40nMAssay Description:Binding affinity to Hsp90 after 4 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
The University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50003868(CHEMBL3235353)
Affinity DataIC50:  6nMAssay Description:Inhibition of HSP90 in Huntington's disease patient derived fibroblasts assessed as reduction of mHtt level after 48 hrs by Western blot analysisMore data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
The University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM20928(5-[2,4-dihydroxy-5-(propan-2-yl)phenyl]-N-ethyl-4-...)
Affinity DataIC50:  6nM EC50:  40nMAssay Description:The assay is based upon displacement of a fluorescently labeled molecule, which binds specifically to the ATP-binding site of full-length human Hsp90...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
The University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM20927(4-{4-[(diethylamino)methyl]phenyl}-5-[2,4-dihydrox...)
Affinity DataIC50:  6nM EC50:  6nMAssay Description:The assay is based upon displacement of a fluorescently labeled molecule, which binds specifically to the ATP-binding site of full-length human Hsp90...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
The University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50378702(CHEMBL560895 | SNX-2112)
Affinity DataIC50:  7nMAssay Description:Inhibition of HSP90-mediated client protein HER2 degradationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
The University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM15359((4E,6Z,8S,9S,10E,12S,13R,14S,16R)-13-hydroxy-8,14-...)
Affinity DataIC50:  7nMAssay Description:Inhibition of HSP90-mediated client protein HER2 degradationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
The University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50030868((8S,9S,12S,13R,14S,16R)-19-amino-13-hydroxy-8,14-d...)
Affinity DataIC50:  7nMAssay Description:Inhibition of HSP90-mediated client protein HER2 degradationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
The University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM20926(5-[2,4-dihydroxy-5-(propan-2-yl)phenyl]-N-ethyl-4-...)
Affinity DataIC50:  7nMAssay Description:Inhibition of HSP90 in Huntington's disease patient derived fibroblasts assessed as reduction of mHtt level after 48 hrs by Western blot analysisMore data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
The University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM20926(5-[2,4-dihydroxy-5-(propan-2-yl)phenyl]-N-ethyl-4-...)
Affinity DataIC50:  7nMAssay Description:Inhibition of HSP90-mediated client protein HER2 degradationMore data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
The University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM20800(2-amino-6-halopurine analogue, 20 | 6-chloro-9-[(4...)
Affinity DataIC50:  7nMAssay Description:Inhibition of HSP90-mediated client protein HER2 degradationMore data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
The University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM20926(5-[2,4-dihydroxy-5-(propan-2-yl)phenyl]-N-ethyl-4-...)
Affinity DataIC50:  7nMAssay Description:Inhibition of HSP90-mediated client protein HER2 degradation in human MCF7 cellsMore data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
The University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50361698(CHEMBL1941047)
Affinity DataIC50:  7.40nMAssay Description:Binding affinity to Hsp90 after 4 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
The University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM20924(5-(5-tert-butyl-2,4-dihydroxyphenyl)-N-ethyl-4-[4-...)
Affinity DataIC50:  8nM EC50:  70nMAssay Description:The assay is based upon displacement of a fluorescently labeled molecule, which binds specifically to the ATP-binding site of full-length human Hsp90...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
The University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM225748(hsp90_45)
Affinity DataIC50:  8.40nMAssay Description:FRET Assay 1More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
The University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50361693(CHEMBL1938422)
Affinity DataIC50:  8.60nMAssay Description:Binding affinity to Hsp90 after 4 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
The University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50361700(CHEMBL1941049)
Affinity DataIC50:  8.80nMAssay Description:Binding affinity to Hsp90 after 4 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
The University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50361719(CHEMBL1941068)
Affinity DataIC50:  10nMAssay Description:Binding affinity to Hsp90 after 4 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
The University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM225839(hsp90_130)
Affinity DataIC50:  10nMAssay Description:FRET Assay 1More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
The University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM225838(hsp90_129)
Affinity DataIC50:  10nMAssay Description:FRET Assay 1More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
The University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50008059(CHEBI:5292 | GELDANAMYCIN)
Affinity DataIC50: <10nMAssay Description:Inhibition of HSP90 in human MDA-kb2 cells assessed as reduction in glucocorticoid receptor-dependent luciferase expression after 18 hrs by firefly l...More data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
The University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM225840(hsp90_131)
Affinity DataIC50:  10nMAssay Description:FRET Assay 1More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
The University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM225866(hsp90_161)
Affinity DataIC50:  10nMAssay Description:FRET Assay 1More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
The University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM225745(hsp90_42)
Affinity DataIC50:  10.8nMAssay Description:FRET Assay 1More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
The University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50379853(CHEMBL2011854)
Affinity DataIC50:  11nMAssay Description:Inhibition of HSP90-mediated pS6 phosphorylation in human A375 cells after 24 hrs by TRITC assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
The University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM20925(5-(5-tert-butyl-2,4-dihydroxyphenyl)-N-ethyl-4-[4-...)
Affinity DataIC50:  11nM EC50:  65nMAssay Description:The assay is based upon displacement of a fluorescently labeled molecule, which binds specifically to the ATP-binding site of full-length human Hsp90...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
The University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM225749(hsp90_46)
Affinity DataIC50:  11.5nMAssay Description:FRET Assay 1More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
The University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM15359((4E,6Z,8S,9S,10E,12S,13R,14S,16R)-13-hydroxy-8,14-...)
Affinity DataIC50:  12nMAssay Description:Inhibition of HSP90-mediated client protein HER2 degradation in human MCF7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
The University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50030868((8S,9S,12S,13R,14S,16R)-19-amino-13-hydroxy-8,14-d...)
Affinity DataIC50:  12nMAssay Description:Inhibition of HSP90-mediated client protein HER2 degradation in human MCF7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
The University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50361697(CHEMBL1940949)
Affinity DataIC50:  12nMAssay Description:Binding affinity to Hsp90 after 4 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
The University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM225738(hsp90_32)
Affinity DataIC50:  12.1nMAssay Description:FRET Assay 1More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
The University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50361695(CHEMBL1940944)
Affinity DataIC50:  12.6nMAssay Description:Binding affinity to Hsp90 after 4 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
The University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM20914(4-{4-[(diethylamino)methyl]phenyl}-N-ethyl-5-(5-et...)
Affinity DataIC50:  13nM EC50:  41nMAssay Description:The assay is based upon displacement of a fluorescently labeled molecule, which binds specifically to the ATP-binding site of full-length human Hsp90...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
The University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM225875(hsp90_174)
Affinity DataIC50:  13.7nMAssay Description:FRET Assay 1More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
The University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM20751(9-[3-(tert-butylamino)propyl]-8-[(2-iodo-5-methoxy...)
Affinity DataIC50:  14nMAssay Description:Inhibition of Hsp90 in human MCF7 cells assessed as Her2 degradationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
The University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50361733(CHEMBL1940943)
Affinity DataIC50:  14nMAssay Description:Binding affinity to Hsp90 after 4 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
The University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM20921(5-[2,4-dihydroxy-5-(2-methylphenyl)phenyl]-N-ethyl...)
Affinity DataIC50:  14nM EC50:  114nMAssay Description:The assay is based upon displacement of a fluorescently labeled molecule, which binds specifically to the ATP-binding site of full-length human Hsp90...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
The University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM20919(5-(2,4-dihydroxy-5-phenylphenyl)-N-ethyl-4-[4-(pip...)
Affinity DataIC50:  14nM EC50:  86nMAssay Description:The assay is based upon displacement of a fluorescently labeled molecule, which binds specifically to the ATP-binding site of full-length human Hsp90...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
The University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM20901(5-(5-chloro-2,4-dihydroxyphenyl)-N-ethyl-4-(4-{[(2...)
Affinity DataIC50:  14nM EC50:  1.98E+3nMpH: 7.4 T: 2°CAssay Description:The assay is based upon displacement of a fluorescently labeled molecule, which binds specifically to the ATP-binding site of full-length human Hsp90...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
The University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM15359((4E,6Z,8S,9S,10E,12S,13R,14S,16R)-13-hydroxy-8,14-...)
Affinity DataIC50:  15nMAssay Description:Inhibition of Hsp90 in human MCF7 cells assessed as Her2 degradationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
The University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50361696(CHEMBL1940947)
Affinity DataIC50:  15nMAssay Description:Binding affinity to Hsp90 after 4 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
The University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM20930(Isoxazole, 70 | N-ethyl-5-(5-ethyl-2-hydroxy-4-met...)
Affinity DataIC50:  15nM EC50:  80nMAssay Description:The assay is based upon displacement of a fluorescently labeled molecule, which binds specifically to the ATP-binding site of full-length human Hsp90...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
The University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50361727(CHEMBL1941076)
Affinity DataIC50:  15nMAssay Description:Binding affinity to Hsp90 after 4 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
The University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM225837(hsp90_128)
Affinity DataIC50:  15.3nMAssay Description:FRET Assay 1More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
The University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM20800(2-amino-6-halopurine analogue, 20 | 6-chloro-9-[(4...)
Affinity DataIC50:  15.6nMAssay Description:FRET Assay 1More data for this Ligand-Target Pair
Displayed 1 to 50 (of 879 total ) | Next | Last >>
Jump to: