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Report error Found 6 of affinity data for UniProtKB/TrEMBL: Q8IXN7
TargetN-acetylaspartylglutamate synthase A(Human)
Johns Hopkins Universty

US Patent
LigandPNGBDBM693144(US12070513, Compound 3)
Affinity DataKi:  0.0100nMAssay Description:NAAG hydrolysis was performed essentially as described previously (26)(27) Briefly, LNCaP cell extracts were prepared by sonication in NAALADase buff...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent


TargetN-acetylaspartylglutamate synthase A(Human)
Johns Hopkins Universty

US Patent
LigandPNGBDBM693144(US12070513, Compound 3)
Affinity DataKi:  0.0100nMAssay Description:PSMA activity was also determined using a fluorescence-based assay according to a previously reported procedure. Briefly, lysates of LNCaP cell extra...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent


TargetN-acetylaspartylglutamate synthase A(Human)
Johns Hopkins Universty

US Patent
LigandPNGBDBM693145(US12070513, Compound 6)
Affinity DataKi:  0.194nMAssay Description:PSMA activity was also determined using a fluorescence-based assay according to a previously reported procedure. Briefly, lysates of LNCaP cell extra...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent


TargetN-acetylaspartylglutamate synthase A(Human)
Johns Hopkins Universty

US Patent
LigandPNGBDBM693145(US12070513, Compound 6)
Affinity DataKi:  0.256nMAssay Description:NAAG hydrolysis was performed essentially as described previously (26)(27) Briefly, LNCaP cell extracts were prepared by sonication in NAALADase buff...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent


TargetN-acetylaspartylglutamate synthase A(Human)
Johns Hopkins Universty

US Patent
LigandPNGBDBM693146(US12070513, Compound 8)
Affinity DataKi:  0.351nMAssay Description:NAAG hydrolysis was performed essentially as described previously (26)(27) Briefly, LNCaP cell extracts were prepared by sonication in NAALADase buff...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent


TargetN-acetylaspartylglutamate synthase A(Human)
Johns Hopkins Universty

US Patent
LigandPNGBDBM693146(US12070513, Compound 8)
Affinity DataKi:  0.557nMAssay Description:PSMA activity was also determined using a fluorescence-based assay according to a previously reported procedure. Briefly, lysates of LNCaP cell extra...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent