Affinity DataIC50: 0.0100nMpH: 7.4Assay Description:Inhibition of human recombinant renin in PBS buffer using tetradecapeptide at pH 7.4More data for this Ligand-Target Pair
Affinity DataIC50: 0.0100nMpH: 7.4Assay Description:Inhibition of human recombinant renin in PBS buffer using tetradecapeptide at pH 7.4More data for this Ligand-Target Pair
Affinity DataIC50: 0.0100nMpH: 7.4Assay Description:Inhibition of human recombinant renin in PBS buffer using tetradecapeptide at pH 7.4More data for this Ligand-Target Pair
Affinity DataIC50: 0.0200nMAssay Description:Inhibition of renin in human plasma using Q-FRET substrate pretreated for 10 mins before substrate addition measured after 1 hrMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0200nMAssay Description:Inhibition of human recombinant renin using Q-FRET substrate after 3 hrs by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0200nMpH: 7.4Assay Description:Inhibition of human recombinant renin in PBS buffer using tetradecapeptide at pH 7.4More data for this Ligand-Target Pair
Affinity DataIC50: 0.0200nMpH: 7.4Assay Description:Inhibition of human recombinant renin in PBS buffer using tetradecapeptide at pH 7.4More data for this Ligand-Target Pair
Affinity DataIC50: 0.0210nMpH: 7.4Assay Description:Inhibition of human recombinant renin in PBS buffer using tetradecapeptide at pH 7.4More data for this Ligand-Target Pair
Affinity DataIC50: 0.0220nMpH: 7.4Assay Description:Inhibition of human recombinant renin in PBS buffer using tetradecapeptide at pH 7.4More data for this Ligand-Target Pair
Affinity DataIC50: 0.0250nMAssay Description:In vitro inhibitory activity against purified recombinant human reninMore data for this Ligand-Target Pair
3D Structure (crystal)
Affinity DataIC50: 0.0270nMpH: 7.4Assay Description:Inhibition of human recombinant renin in PBS buffer using tetradecapeptide at pH 7.4More data for this Ligand-Target Pair
Affinity DataIC50: 0.0280nMpH: 7.4Assay Description:Inhibition of human recombinant renin in PBS buffer using tetradecapeptide at pH 7.4More data for this Ligand-Target Pair
Affinity DataIC50: 0.0280nMpH: 7.4Assay Description:Inhibition of human recombinant renin in PBS buffer using tetradecapeptide at pH 7.4More data for this Ligand-Target Pair
Affinity DataIC50: 0.0300nMpH: 7.4Assay Description:Inhibition of human recombinant renin in PBS buffer using tetradecapeptide at pH 7.4More data for this Ligand-Target Pair
Affinity DataIC50: 0.0300nMAssay Description:Inhibition of human recombinant renin using DNP-Lys-His-Pro-Phe-His-Leu-Val-Ile-His-D,L-Amp as Q-FRET substrate after 3 hrs by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0300nMAssay Description:Compound was tested for its inhibitory activity against dog plasma reninMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0390nMAssay Description:Inhibition of human recombinant renin in bufferMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0390nMAssay Description:Inhibition of human recombinant rennin in buffer assessed as accumulation of angiotensin 1 using human tetradecapeptide by immunoassayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0390nMAssay Description:Inhibition of recombinant human preprorenin expressed in human 293F cells using angiotensinogen as substrate preincubated for 10 mins followed by sub...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0390nMAssay Description:Inhibition of recombinant human preprorenin expressed in human 293F cells using angiotensinogen as substrate preincubated for 10 mins followed by sub...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0400nMAssay Description:Inhibition of human recombinant renin using DNP-Lys-His-Pro-Phe-His-Leu-Val-Ile-His-D,L-Amp as Q-FRET substrate after 3 hrs by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0400nMAssay Description:Inhibition of human recombinant renin using DNP-Lys-His-Pro-Phe-His-Leu-Val-Ile-His-D,L-Amp as Q-FRET substrate after 3 hrs by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0400nMpH: 7.4Assay Description:Inhibition of human recombinant renin in PBS buffer using tetradecapeptide at pH 7.4More data for this Ligand-Target Pair
Affinity DataIC50: 0.0400nMAssay Description:Inhibition of human recombinant renin in phosphate bufferMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0400nMAssay Description:Inhibition of human recombinant renin using DNP-Lys-His-Pro-Phe-His-Leu-Val-Ile-His-D,L-Amp as Q-FRET substrate after 3 hrs by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0400nMAssay Description:Inhibition of renin in bufferMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0460nMpH: 7.4Assay Description:Inhibition of human recombinant renin in PBS buffer using tetradecapeptide at pH 7.4More data for this Ligand-Target Pair
Affinity DataIC50: 0.0500nMpH: 7.4Assay Description:Inhibition of recombinant human renin using 9 DNP-Lys-His-Pro-Phe-His-Leu-Val-Ile-His-D,L-Amp as substrate after 3 hrs by Q-FRET assay in presence of...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0500nMAssay Description:Inhibition of human recombinant renin using DNP-Lys-His-Pro-Phe-His-Leu-Val-Ile-His-D,L-Amp as substrate after 3 hrs by fluorimetryMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0500nMAssay Description:Inhibition of human recombinant renin using DNP-Lys-His-Pro-Phe-His-Leu-Val-Ile-His-D,L-Amp as Q-FRET substrate after 3 hrs by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0500nMAssay Description:Inhibition of human recombinant renin using Q-FRET substrate after 3 hrs by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0500nMAssay Description:Inhibition of renin in bufferMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0500nMAssay Description:Inhibition of renin in bufferMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0500nMAssay Description:Inhibition of renin in bufferMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0600nMpH: 7.4Assay Description:Inhibition of human recombinant renin in PBS buffer using tetradecapeptide at pH 7.4More data for this Ligand-Target Pair
Affinity DataIC50: 0.0600nMAssay Description:Inhibition of human recombinant renin using Q-FRET substrate after 3 hrs by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0600nMAssay Description:In vitro inhibitory activity against purified recombinant human reninMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0600nMAssay Description:Inhibition of human recombinant renin in bufferMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0600nMAssay Description:Inhibition of human recombinant renin using DNP-Lys-His-Pro-Phe-His-Leu-Val-Ile-His-D,L-Amp as Q-FRET substrate after 3 hrs by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0600nMAssay Description:Inhibition of human recombinant renin using DNP-Lys-His-Pro-Phe-His-Leu-Val-Ile-His-D,L-Amp as substrate after 3 hrs by fluorescence analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0600nMpH: 7.4Assay Description:Inhibition of human recombinant renin in PBS buffer using tetradecapeptide at pH 7.4More data for this Ligand-Target Pair
Affinity DataIC50: 0.0640nMpH: 7.4Assay Description:Inhibition of human recombinant renin in PBS buffer using tetradecapeptide at pH 7.4More data for this Ligand-Target Pair
Affinity DataIC50: 0.0670nMAssay Description:Inhibition of human recombinant renin in bufferMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0670nMpH: 7.4 T: 2°CAssay Description:The renin assay utilized a tandem Green Flourescent Protein (tGFP) substrate that was hydrolyzed by human rennin. The tGFP substrate contained a nine...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0670nMAssay Description:Inhibition of human recombinant reninMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0670nMAssay Description:Inhibition of recombinant human reninMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0700nMAssay Description:Inhibition of human recombinant renin using DNP-Lys-His-Pro-Phe-His-Leu-Val-Ile-His-D,L-Amp as Q-FRET substrate after 3 hrs by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0700nMAssay Description:Inhibition of human recombinant renin using Q-FRET substrate after 3 hrs by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0700nMAssay Description:Inhibition of renin in bufferMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0700nMpH: 7.4Assay Description:Inhibition of recombinant human renin using 9 DNP-Lys-His-Pro-Phe-His-Leu-Val-Ile-His-D,L-Amp as substrate after 3 hrs by Q-FRET assay in presence of...More data for this Ligand-Target Pair
