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TargetLysosomal acid glucosylceramidase(Human)
Northwestern University

US Patent
LigandPNGBDBM313453(US10167270, Example 160)
Affinity DataKd:  7.10nMAssay Description:The enzyme in GCase enzyme activity buffer (25 μL/well) was added to a 384-well black plate. The fluorescent probe 3 (25 nL/well, 50 nM final co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
US Patent

TargetLysosomal acid glucosylceramidase(Human)
Northwestern University

US Patent
LigandPNGBDBM50639863(CHEMBL5560927)
Affinity DataKd:  18nMAssay Description:Binding affinity to human Avi/10-his tagged GCase (40 to 536 residues) expressed baculovirus expression system in Sf9 cells in assessed as dissociati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Northwestern University

US Patent
LigandPNGBDBM50639862(CHEMBL5567650)
Affinity DataKd:  19nMAssay Description:Binding affinity to human Avi/10-his tagged GCase (40 to 536 residues) expressed baculovirus expression system in Sf9 cells in assessed as dissociati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Northwestern University

US Patent
LigandPNGBDBM50639868(CHEMBL5562071)
Affinity DataKd:  50nMAssay Description:Binding affinity to human Avi/10-his tagged GCase (40 to 536 residues) expressed baculovirus expression system in Sf9 cells in assessed as dissociati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetLysosomal acid glucosylceramidase(Human)
Northwestern University

US Patent
LigandPNGBDBM313451(US10167270, Example 158)
Affinity DataKd:  79nMAssay Description:The enzyme in GCase enzyme activity buffer (25 μL/well) was added to a 384-well black plate. The fluorescent probe 3 (25 nL/well, 50 nM final co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
US Patent

TargetLysosomal acid glucosylceramidase(Human)
Northwestern University

US Patent
LigandPNGBDBM313452(US10167270, Example 159)
Affinity DataKd:  126nMAssay Description:The enzyme in GCase enzyme activity buffer (25 μL/well) was added to a 384-well black plate. The fluorescent probe 3 (25 nL/well, 50 nM final co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
US Patent

TargetLysosomal acid glucosylceramidase(Human)
Northwestern University

US Patent
LigandPNGBDBM50639861(CHEMBL5562221)
Affinity DataKd:  180nMAssay Description:Binding affinity to human Avi/10-his tagged GCase (40 to 536 residues) expressed baculovirus expression system in Sf9 cells in assessed as dissociati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Northwestern University

US Patent
LigandPNGBDBM50639867(CHEMBL5563159)
Affinity DataKd:  220nMAssay Description:Binding affinity to human Avi/10-his tagged GCase (40 to 536 residues) expressed baculovirus expression system in Sf9 cells in assessed as dissociati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Northwestern University

US Patent
LigandPNGBDBM50639865(CHEMBL5567786)
Affinity DataKd:  250nMAssay Description:Binding affinity to human Avi/10-his tagged GCase (40 to 536 residues) expressed baculovirus expression system in Sf9 cells in assessed as dissociati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Northwestern University

US Patent
LigandPNGBDBM50639864(CHEMBL5565566)
Affinity DataKd:  300nMAssay Description:Binding affinity to human Avi/10-his tagged GCase (40 to 536 residues) expressed baculovirus expression system in Sf9 cells in assessed as dissociati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetLysosomal acid glucosylceramidase(Human)
Northwestern University

US Patent
LigandPNGBDBM50639860(CHEMBL5560175)
Affinity DataKd:  310nMAssay Description:Binding affinity to human Avi/10-his tagged GCase (40 to 536 residues) expressed baculovirus expression system in Sf9 cells in assessed as dissociati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetLysosomal acid glucosylceramidase(Human)
Northwestern University

US Patent
LigandPNGBDBM50639859(CHEMBL5563549)
Affinity DataKd:  1.00E+3nMAssay Description:Binding affinity to human Avi/10-his tagged GCase (40 to 536 residues) expressed baculovirus expression system in Sf9 cells in assessed as dissociati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetLysosomal acid glucosylceramidase(Human)
Northwestern University

US Patent
LigandPNGBDBM50639866(CHEMBL5555937)
Affinity DataKd:  1.10E+3nMAssay Description:Binding affinity to human Avi/10-his tagged GCase (40 to 536 residues) expressed baculovirus expression system in Sf9 cells in assessed as dissociati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Northwestern University

US Patent
LigandPNGBDBM50639858(CHEMBL5559958)
Affinity DataKd:  3.00E+3nMAssay Description:Binding affinity to human Avi/10-his tagged GCase (40 to 536 residues) expressed baculovirus expression system in Sf9 cells in assessed as dissociati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Northwestern University

US Patent
LigandPNGBDBM50639857(CHEMBL5560911)
Affinity DataKd:  7.00E+3nMAssay Description:Binding affinity to human Avi/10-his tagged GCase (40 to 536 residues) expressed baculovirus expression system in Sf9 cells in assessed as dissociati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Northwestern University

US Patent
LigandPNGBDBM50004317(CHEMBL144129 | 4-Benzyl-piperidine | EN300-19578)
Affinity DataKd:  1.90E+4nMAssay Description:Binding affinity to human Avi/10-his tagged GCase (40 to 536 residues) expressed baculovirus expression system in Sf9 cells in assessed as dissociati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetLysosomal acid glucosylceramidase(Human)
Northwestern University

US Patent
LigandPNGBDBM50117271(CHEMBL558 | 2-(2,6-Dimethyl-phenoxy)-1-methyl-ethy...)
Affinity DataKd:  3.70E+4nMAssay Description:Binding affinity to human Avi/10-his tagged GCase (40 to 536 residues) expressed baculovirus expression system in Sf9 cells in assessed as dissociati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Northwestern University

US Patent
LigandPNGBDBM50639856(CHEMBL5555347)
Affinity DataKd:  1.00E+5nMAssay Description:Binding affinity to human Avi/10-his tagged GCase (40 to 536 residues) expressed baculovirus expression system in Sf9 cells in assessed as dissociati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Northwestern University

US Patent
LigandPNGBDBM50639855(CHEMBL5564772)
Affinity DataKd:  1.80E+5nMAssay Description:Binding affinity to human Avi/10-his tagged GCase (40 to 536 residues) expressed baculovirus expression system in Sf9 cells in assessed as dissociati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Northwestern University

US Patent
LigandPNGBDBM50639854(CHEMBL5561451)
Affinity DataKd:  4.10E+5nMAssay Description:Binding affinity to human Avi/10-his tagged GCase (40 to 536 residues) expressed baculovirus expression system in Sf9 cells in assessed as dissociati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMedPDB3D3D Structure (crystal)