Compile Data Set for Download or QSAR
Report error Found 895 of ec50 for UniProtKB: Q92847
TargetGrowth hormone secretagogue receptor type 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50412965(CHEMBL480821)
Affinity DataEC50:  0.0501nMAssay Description:Agonist activity at human ghrelin receptor by cell based BACMAM FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50280856(CHEMBL4172656)
Affinity DataEC50:  0.100nMAssay Description:Agonist activity at human GHS receptor assessed as intracellular myo-IP1 secretion after 90 mins by HTRF analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2020
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50280856(CHEMBL4172656)
Affinity DataEC50:  0.100nMAssay Description:Agonist activity at human GHS receptor assessed as intracellular myo-IP1 secretion after 90 mins by HTRF analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2020
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50544367(CHEMBL4641513)
Affinity DataEC50:  0.145nMAssay Description:Agonist activity at human GHSR expressed in HEK293 cells assessed as increase in IP1 accumulation measured after 90 mins in presence of LiCl by HTRF ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50412966(CHEMBL481013)
Affinity DataEC50:  0.158nMAssay Description:Agonist activity at human ghrelin receptor by cell based BACMAM FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50412954(SB-791016 | SB-791016A | CHEMBL251572)
Affinity DataEC50:  0.158nMAssay Description:Agonist activity at human ghrelin receptor by cell based BACMAM FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50544361(CHEMBL4635542)
Affinity DataEC50:  0.158nMAssay Description:Agonist activity at human GHSR expressed in HEK293 cells assessed as increase in IP1 accumulation measured after 90 mins in presence of LiCl by HTRF ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50412954(SB-791016 | SB-791016A | CHEMBL251572)
Affinity DataEC50:  0.158nMAssay Description:Agonist activity at GSHR by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50544367(CHEMBL4641513)
Affinity DataEC50:  0.158nMAssay Description:Agonist activity at human GHSR expressed in HEK293 cells assessed as increase in IP1 accumulation measured after 90 mins in presence of LiCl by HTRF ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50544361(CHEMBL4635542)
Affinity DataEC50:  0.168nMAssay Description:Agonist activity at human GHSR expressed in HEK293 cells assessed as increase in IP1 accumulation measured after 90 mins in presence of LiCl by HTRF ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50477764(CHEMBL401134)
Affinity DataEC50:  0.200nMAssay Description:Agonist activity at GSHR by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50544368(CHEMBL4638297)
Affinity DataEC50:  0.200nMAssay Description:Agonist activity at human GHSR expressed in HEK293 cells assessed as increase in IP1 accumulation measured after 90 mins in presence of LiCl by HTRF ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50412978(CHEMBL518774)
Affinity DataEC50:  0.200nMAssay Description:Agonist activity at human ghrelin receptor by cell based BACMAM FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50376781(CHEMBL410085)
Affinity DataEC50:  0.200nMAssay Description:Agonist activity at human GHS receptor expressed in H4 cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50376783(CHEMBL259166)
Affinity DataEC50:  0.200nMAssay Description:Agonist activity at human GHS receptor expressed in H4 cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50376760(CHEMBL410074)
Affinity DataEC50:  0.200nMAssay Description:Agonist activity at human GHS receptor expressed in H4 cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM19386(6-[(benzyloxy)methyl]-5-(4-{[(4-nitrophenyl)methyl...)
Affinity DataIC50: 0.200nM EC50:  5.80nMpH: 7.4 T: 2°CAssay Description:Specific binding was determined by incubation of membranes from GHS-R1a transfected CHO-K cells with 125I-His9-ghrelin in the presence of increasing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2007
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50544368(CHEMBL4638297)
Affinity DataEC50:  0.210nMAssay Description:Agonist activity at human GHSR expressed in HEK293 cells assessed as increase in IP1 accumulation measured after 90 mins in presence of LiCl by HTRF ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50544379(CHEMBL4643530)
Affinity DataEC50:  0.235nMAssay Description:Agonist activity at human GHSR expressed in HEK293 cells assessed as increase in IP1 accumulation measured after 90 mins in presence of LiCl by HTRF ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50412963(CHEMBL481796)
Affinity DataEC50:  0.251nMAssay Description:Agonist activity at human ghrelin receptor by cell based BACMAM FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50544363(CHEMBL4640507)
Affinity DataEC50:  0.251nMAssay Description:Agonist activity at human GHSR expressed in HEK293 cells assessed as increase in IP1 accumulation measured after 90 mins in presence of LiCl by HTRF ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50544379(CHEMBL4643530)
Affinity DataEC50:  0.251nMAssay Description:Agonist activity at human GHSR expressed in HEK293 cells assessed as increase in IP1 accumulation measured after 90 mins in presence of LiCl by HTRF ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50243597((R)-2-(5-(1-(2-amino-2-methylpropanamido)-4,4-difl...)
Affinity DataEC50:  0.270nMAssay Description:Agonist activity at GHS receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50544363(CHEMBL4640507)
Affinity DataEC50:  0.274nMAssay Description:Agonist activity at human GHSR expressed in HEK293 cells assessed as increase in IP1 accumulation measured after 90 mins in presence of LiCl by HTRF ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50206768(4-((R)-1-{(R)-1-[((S)-carbamoyl-phenyl-methyl)-car...)
Affinity DataEC50:  0.280nMAssay Description:Agonist activity at human GHS-R1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM19331(CHEMBL266063 | N-[(1R)-2-(1H-indol-3-yl)-1-{5-[2-(...)
Affinity DataIC50: 0.300nM EC50:  3nMAssay Description:Specific binding was determined by incubation of membranes from GHS-R1a transfected LLC cells with 125I-His9-ghrelin in the presence of increasing co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2007
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM19387(CHEMBL425594 | 6-[(benzyloxy)methyl]-5-(4-{[(4-met...)
Affinity DataIC50: 0.300nM EC50:  7.20nMpH: 7.4 T: 2°CAssay Description:Specific binding was determined by incubation of membranes from GHS-R1a transfected CHO-K cells with 125I-His9-ghrelin in the presence of increasing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2007
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50371684(CHEMBL270666)
Affinity DataEC50:  0.300nMAssay Description:Agonist activity at human GHS receptor expressed in H4 glioma cells assessed as intracellular calcium concentration by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50412972(CHEMBL482220)
Affinity DataEC50:  0.316nMAssay Description:Agonist activity at human ghrelin receptor by cell based BACMAM FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50544388(CHEMBL4645043)
Affinity DataEC50: >0.316nMAssay Description:Agonist activity at human GHSR expressed in HEK293 cells assessed as increase in IP1 accumulation measured after 90 mins in presence of LiCl by HTRF ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50544366(CHEMBL4647963)
Affinity DataEC50:  0.316nMAssay Description:Agonist activity at human GHSR expressed in HEK293 cells assessed as increase in IP1 accumulation measured after 90 mins in presence of LiCl by HTRF ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50544388(CHEMBL4645043)
Affinity DataEC50: <0.320nMAssay Description:Agonist activity at human GHSR expressed in HEK293 cells assessed as increase in IP1 accumulation measured after 90 mins in presence of LiCl by HTRF ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50544366(CHEMBL4647963)
Affinity DataEC50:  0.335nMAssay Description:Agonist activity at human GHSR expressed in HEK293 cells assessed as increase in IP1 accumulation measured after 90 mins in presence of LiCl by HTRF ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50235838((4-hydroxy-butyl)-carbamic acid 2-{5-[(S)-1-(2-ami...)
Affinity DataEC50:  0.340nMAssay Description:Inhibition of human growth hormone secretagogue receptor assessed as measuring intracellular calcium level by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50066101(Piperidine-4-carboxylic acid {1-[1-(carbamoylmethy...)
Affinity DataEC50:  0.340nMAssay Description:Compound was evaluated for GH release for effect on human GH secretagogue receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50412973(CHEMBL519301)
Affinity DataEC50:  0.398nMAssay Description:Agonist activity at human ghrelin receptor by cell based BACMAM FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50544364(CHEMBL4639229)
Affinity DataEC50:  0.398nMAssay Description:Agonist activity at human GHSR expressed in HEK293 cells assessed as increase in IP1 accumulation measured after 90 mins in presence of LiCl by HTRF ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50544378(CHEMBL4639111)
Affinity DataEC50:  0.398nMAssay Description:Agonist activity at human GHSR expressed in HEK293 cells assessed as increase in IP1 accumulation measured after 90 mins in presence of LiCl by HTRF ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50544364(CHEMBL4639229)
Affinity DataEC50:  0.398nMAssay Description:Agonist activity at human GHSR expressed in HEK293 cells assessed as increase in IP1 accumulation measured after 90 mins in presence of LiCl by HTRF ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50544378(CHEMBL4639111)
Affinity DataEC50:  0.398nMAssay Description:Agonist activity at human GHSR expressed in HEK293 cells assessed as increase in IP1 accumulation measured after 90 mins in presence of LiCl by HTRF ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50049478(1-{[(2R)-3-(benzyloxy)-1-{1-methanesulfonyl-1,2-di...)
Affinity DataEC50:  0.398nMAssay Description:Agonist activity at human GHS receptor assessed as intracellular myo-IP1 secretion after 90 mins by HTRF analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGrowth hormone secretagogue receptor type 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50478232(CHEMBL260819)
Affinity DataEC50:  0.398nMAssay Description:Agonist activity at human GHSR1a by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2020
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50049478(1-{[(2R)-3-(benzyloxy)-1-{1-methanesulfonyl-1,2-di...)
Affinity DataEC50:  0.400nMAssay Description:Agonist activity at human GHS receptor assessed as intracellular myo-IP1 secretion after 90 mins by HTRF analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGrowth hormone secretagogue receptor type 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50371688(CHEMBL404545)
Affinity DataEC50:  0.400nMAssay Description:Agonist activity at human GHS receptor expressed in H4 glioma cells assessed as intracellular calcium concentration by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50371686(CHEMBL271876)
Affinity DataEC50:  0.400nMAssay Description:Agonist activity at human GHS receptor expressed in H4 glioma cells assessed as intracellular calcium concentration by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50235845((S)-2-(5-(2-(2,4-difluorobenzyloxy)-1-(2-amino-2-m...)
Affinity DataEC50:  0.420nMAssay Description:Inhibition of human growth hormone secretagogue receptor assessed as measuring intracellular calcium level by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50235842((S)-2-(5-(2-(2-chlorobenzyloxy)-1-(2-amino-2-methy...)
Affinity DataEC50:  0.450nMAssay Description:Inhibition of human growth hormone secretagogue receptor assessed as measuring intracellular calcium level by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50544362(CHEMBL4646219)
Affinity DataEC50:  0.455nMAssay Description:Agonist activity at human GHSR expressed in HEK293 cells assessed as increase in IP1 accumulation measured after 90 mins in presence of LiCl by HTRF ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50410108(CHEMBL179823)
Affinity DataEC50:  0.460nMAssay Description:In vitro effective concentration against human growth hormone secretagoguesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50410123(CHEMBL180094)
Affinity DataEC50:  0.460nMAssay Description:In vivo effective concentration against human growth hormone secretagoguesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
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