Compile Data Set for Download or QSAR
Report error Found 71 of kd for UniProtKB: P29274
TargetAdenosine receptor A2a(Human)
Neuroscience

LigandPNGBDBM21190(CHEMBL113142 | 4-(2-{[5-amino-2-(furan-2-yl)-[1,2,...)
Affinity DataKd:  0.220nMpH: 7.4 T: 2°CAssay Description:The membranes prepared from Flp-In HEK cells transfected with adenosine receptors were used in binding assays. Nonspecific binding was determined in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/7/2008
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Neuroscience

LigandPNGBDBM21190(CHEMBL113142 | 4-(2-{[5-amino-2-(furan-2-yl)-[1,2,...)
Affinity DataKd:  0.220nMAssay Description:The membranes prepared from Flp-In HEK cells transfected with adenosine receptors were used in binding assays. Nonspecific binding was determined in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2008
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Neuroscience

LigandPNGBDBM50148598(Evodenoson | ATL-313 | DE-112)
Affinity DataKd:  0.700nMAssay Description:Displacement of 2-[2-(4-amino-3-[125I]iodophenyl)ethylamino]adenosine from human recombinant adenosine A2A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2017
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Neuroscience

LigandPNGBDBM50595579(CHEMBL5203469)
Affinity DataKd:  1.80nMAssay Description:Displacement of [3H] ZM241385 from human A2AAR S227A mutant expressed in CHO cells assessed as dissociation constant incubated for 60 mins by radioli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetAdenosine receptor A2a(Human)
Neuroscience

LigandPNGBDBM50595579(CHEMBL5203469)
Affinity DataKd:  2nMAssay Description:Displacement of [3H] ZM241385 from wild type human A2AAR expressed in CHO cells assessed as dissociation constant incubated for 60 mins by radioligan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetAdenosine receptor A2a(Human)
Neuroscience

LigandPNGBDBM50026816(CHEMBL3335523)
Affinity DataKd:  2.20nMAssay Description:Displacement of [3H]4-[2-[7-amino-2-(2-furyl)-1,2,4-triazolo[1,5-a][1,3,5]triazin-5-yl-amino]ethylphenol from wild type human adenosine A2a receptor ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2016
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Neuroscience

LigandPNGBDBM50595579(CHEMBL5203469)
Affinity DataKd:  2.70nMAssay Description:Displacement of [3H] ZM241385 from human A2AAR S277A/H278A double mutant expressed in CHO cells assessed as dissociation constant incubated for 60 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetAdenosine receptor A2a(Human)
Neuroscience

LigandPNGBDBM50595579(CHEMBL5203469)
Affinity DataKd:  2.90nMAssay Description:Displacement of [3H] ZM241385 from human A2AAR H278A mutant expressed in CHO cells assessed as dissociation constant incubated for 60 mins by radioli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetAdenosine receptor A2a(Human)
Neuroscience

LigandPNGBDBM50026816(CHEMBL3335523)
Affinity DataKd:  3.20nMAssay Description:Displacement of [3H]4-[2-[7-amino-2-(2-furyl)-1,2,4-triazolo[1,5-a][1,3,5]triazin-5-yl-amino]ethylphenol from wild type human adenosine A2a receptor ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2016
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Neuroscience

LigandPNGBDBM50026818(CHEMBL3335524)
Affinity DataKd:  3.20nMAssay Description:Displacement of [3H]4-[2-[7-amino-2-(2-furyl)-1,2,4-triazolo[1,5-a][1,3,5]triazin-5-yl-amino]ethylphenol from wild type human adenosine A2a receptor ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2016
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Neuroscience

LigandPNGBDBM35804(3-(4-{2-[6-Amino-9-((2R,3R,4S,5S)-5-ethylcarbamoyl...)
Affinity DataKd:  4.30nMpH: 5.5Assay Description:Saturation binding of mutant human Adenosine A2A receptor (H250N) at pH 5.5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAdenosine receptor A2a(Human)
Neuroscience

LigandPNGBDBM35804(3-(4-{2-[6-Amino-9-((2R,3R,4S,5S)-5-ethylcarbamoyl...)
Affinity DataKd:  4.40nMAssay Description:Displacement of [3H]4-[2-[7-amino-2-(2-furyl)-1,2,4-triazolo[1,5-a][1,3,5]triazin-5-yl-amino]ethylphenol from wild type human adenosine A2a receptor ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAdenosine receptor A2a(Human)
Neuroscience

LigandPNGBDBM50026816(CHEMBL3335523)
Affinity DataKd:  5nMAssay Description:Displacement of [3H]4-[2-[7-amino-2-(2-furyl)-1,2,4-triazolo[1,5-a][1,3,5]triazin-5-yl-amino]ethylphenol from wild type human adenosine A2a receptor ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2016
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Neuroscience

LigandPNGBDBM35804(3-(4-{2-[6-Amino-9-((2R,3R,4S,5S)-5-ethylcarbamoyl...)
Affinity DataKd:  7.60nMpH: 6.8Assay Description:Saturation binding of human Adenosine A2A receptor (H250N) at pH 6.8More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAdenosine receptor A2a(Human)
Neuroscience

LigandPNGBDBM35804(3-(4-{2-[6-Amino-9-((2R,3R,4S,5S)-5-ethylcarbamoyl...)
Affinity DataKd:  7.60nMAssay Description:Kd in saturation experiments using [3H]CGS-21680 at H250N mutant receptor in COS-7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAdenosine receptor A2a(Human)
Neuroscience

LigandPNGBDBM82022(N6-Phenylado | 2-[6-Amino-2-(3-cyclohexyl-propylam...)
Affinity DataKd:  9.10nMAssay Description:Binding affinity to human wild type adenosine A2A receptor expressed in Expi293F cells assessed as dissociation constant by surface plasmon resonance...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetAdenosine receptor A2a(Human)
Neuroscience

LigandPNGBDBM35804(3-(4-{2-[6-Amino-9-((2R,3R,4S,5S)-5-ethylcarbamoyl...)
Affinity DataKd:  12nMpH: 7.5Assay Description:Saturation binding of human Adenosine A2A receptor H250N at pH 7.5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAdenosine receptor A2a(Human)
Neuroscience

LigandPNGBDBM14487([U-14C]adenosine | CHEMBL477 | cid_60961 | (2R,3R,...)
Affinity DataKd:  17nMAssay Description:Binding affinity to human wild type adenosine A2A receptor expressed in Expi293F cells assessed as dissociation constant by surface plasmon resonance...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetAdenosine receptor A2a(Human)
Neuroscience

LigandPNGBDBM50342519(triethylammonium 5-(2-(2-(4-(3-(5-amino-2-(furan-2...)
Affinity DataKd:  17nMAssay Description:Binding affinity to human A2A adenosine receptor expressed in HEK293 cells after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2019
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Neuroscience

LigandPNGBDBM35804(3-(4-{2-[6-Amino-9-((2R,3R,4S,5S)-5-ethylcarbamoyl...)
Affinity DataKd:  22nMpH: 5.5Assay Description:Saturation binding characteristics of wild type human Adenosine A2A receptor at pH 5.5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAdenosine receptor A2a(Human)
Neuroscience

LigandPNGBDBM35804(3-(4-{2-[6-Amino-9-((2R,3R,4S,5S)-5-ethylcarbamoyl...)
Affinity DataKd:  27nMAssay Description:Kd in saturation experiments using [3H]CGS-21680 at V84L mutant receptor in COS-7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAdenosine receptor A2a(Human)
Neuroscience

LigandPNGBDBM50583640(CHEMBL5075285)
Affinity DataKd:  28nMAssay Description:Binding affinity to NLuc human A2A adenosine receptor expressed in HEK293-A cells in presence of 1 uM ZM241385 by NanoBRET binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Neuroscience

LigandPNGBDBM50342519(triethylammonium 5-(2-(2-(4-(3-(5-amino-2-(furan-2...)
Affinity DataKd:  29nMAssay Description:Binding affinity to C-terminal 10xHis and 1D4-tagged C-terminal-truncated human A2A adenosine receptor (1 to 316 residues) expressed in Pichia pastor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2019
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Neuroscience

LigandPNGBDBM21173(DPCPX | CHEMBL183 | 8-cyclopentyl-1,3-dipropyl-2,3...)
Affinity DataKd:  30nMpH: 7.4 T: 2°CAssay Description:Aliquots of cell membranes (30 ug) were incubated at 25 °C for 90 min in 500 uL of binding buffer (50 mM Tris-HCl, 2 mm MgCl2, 2 units/mL ADA, pH...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2016
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Neuroscience

LigandPNGBDBM50342519(triethylammonium 5-(2-(2-(4-(3-(5-amino-2-(furan-2...)
Affinity DataKd:  31nMAssay Description:Binding affinity to C-terminal 10xHis and 1D4-tagged C-terminal-truncated human A2A adenosine receptor (1 to 316 residues) expressed in Pichia pastor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2019
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Neuroscience

LigandPNGBDBM35804(3-(4-{2-[6-Amino-9-((2R,3R,4S,5S)-5-ethylcarbamoyl...)
Affinity DataKd:  36nMpH: 6.8Assay Description:Saturation binding of wild type human Adenosine A2A receptor at pH 6.8More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAdenosine receptor A2a(Human)
Neuroscience

LigandPNGBDBM35804(3-(4-{2-[6-Amino-9-((2R,3R,4S,5S)-5-ethylcarbamoyl...)
Affinity DataKd:  36nMAssay Description:Kd in saturation experiments using [3H]CGS-21680 at WT receptor in COS-7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAdenosine receptor A2a(Human)
Neuroscience

LigandPNGBDBM50342519(triethylammonium 5-(2-(2-(4-(3-(5-amino-2-(furan-2...)
Affinity DataKd:  42nMAssay Description:Binding affinity to C-terminal 10xHis and 1D4-tagged C-terminal-truncated human A2A adenosine receptor (1 to 316 residues) expressed in Pichia pastor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2019
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Neuroscience

LigandPNGBDBM50583644(CHEMBL5080679)
Affinity DataKd:  50nMAssay Description:Binding affinity to NLuc human A2A adenosine receptor expressed in HEK293-A cells in presence of 1 uM ZM241385 by NanoBRET binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Neuroscience

LigandPNGBDBM50342519(triethylammonium 5-(2-(2-(4-(3-(5-amino-2-(furan-2...)
Affinity DataKd:  50nMAssay Description:Binding affinity to C-terminal 10xHis and 1D4-tagged C-terminal-truncated human A2A adenosine receptor (1 to 316 residues) expressed in Pichia pastor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2019
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Neuroscience

LigandPNGBDBM35804(3-(4-{2-[6-Amino-9-((2R,3R,4S,5S)-5-ethylcarbamoyl...)
Affinity DataKd:  74nMpH: 7.5Assay Description:Saturation binding characteristics of wild type human Adenosine A2A receptor at pH 7.5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAdenosine receptor A2a(Human)
Neuroscience

LigandPNGBDBM35804(3-(4-{2-[6-Amino-9-((2R,3R,4S,5S)-5-ethylcarbamoyl...)
Affinity DataKd:  99nMpH: 8.4Assay Description:Saturation binding of human Adenosine A2A receptor H250N at pH 8.4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAdenosine receptor A2a(Human)
Neuroscience

LigandPNGBDBM8246(3-[(3-chloro-4-hydroxyphenyl)amino]-4-(3-chlorophe...)
Affinity DataKd:  110nMAssay Description:Binding affinity to human wild type adenosine A2A receptor expressed in Expi293F cells assessed as dissociation constant by surface plasmon resonance...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetAdenosine receptor A2a(Human)
Neuroscience

LigandPNGBDBM21190(CHEMBL113142 | 4-(2-{[5-amino-2-(furan-2-yl)-[1,2,...)
Affinity DataKd:  286nMAssay Description:Binding affinity to human wild type adenosine A2A receptor expressed in Expi293F cells assessed as dissociation constant by surface plasmon resonance...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetAdenosine receptor A2a(Human)
Neuroscience

LigandPNGBDBM8392(CHEMBL408564 | N-[5-bromo-6-(furan-2-yl)-1H-pyrazo...)
Affinity DataKd:  560nMAssay Description:Binding affinity to human wild type adenosine A2A receptor expressed in Expi293F cells assessed as dissociation constant by surface plasmon resonance...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetAdenosine receptor A2a(Human)
Neuroscience

LigandPNGBDBM35804(3-(4-{2-[6-Amino-9-((2R,3R,4S,5S)-5-ethylcarbamoyl...)
Affinity DataKd:  632nMpH: 8.4Assay Description:Saturation binding of wild type human Adenosine A2A receptor at pH 8.4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAdenosine receptor A2a(Human)
Neuroscience

LigandPNGBDBM50583641(CHEMBL5086197)
Affinity DataKd: <1.00E+3nMAssay Description:Binding affinity to NLuc human A2A adenosine receptor expressed in HEK293-A cells in presence of 1 uM ZM241385 by NanoBRET binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Neuroscience

LigandPNGBDBM50207720(CHEMBL3954022)
Affinity DataKd:  1.11E+3nMAssay Description:Binding affinity to human wild type adenosine A2A receptor expressed in Expi293F cells assessed as dissociation constant by surface plasmon resonance...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetAdenosine receptor A2a(Human)
Neuroscience

LigandPNGBDBM50595380(BENZOGUANAMINE)
Affinity DataKd:  1.50E+3nMAssay Description:Binding affinity to human wild type adenosine A2A receptor expressed in Expi293F cells assessed as dissociation constant by surface plasmon resonance...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetAdenosine receptor A2a(Human)
Neuroscience

LigandPNGBDBM10847(Theophylline (1,3-dimethylxanthine) | 1,3-dimethyl...)
Affinity DataKd:  3.63E+3nMAssay Description:Binding affinity to human wild type adenosine A2A receptor expressed in Expi293F cells assessed as dissociation constant by surface plasmon resonance...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetAdenosine receptor A2a(Human)
Neuroscience

LigandPNGBDBM10849(CHEMBL113 | 1,3,7-trimethyl-3,7-dihydropurine-2,6-...)
Affinity DataKd:  5.51E+3nMAssay Description:Binding affinity to human wild type adenosine A2A receptor expressed in Expi293F cells assessed as dissociation constant by surface plasmon resonance...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetAdenosine receptor A2a(Human)
Neuroscience

LigandPNGBDBM50275499(2-(4-fluorophenyl)-3-(4-pyridinyl)pyrazolo-[1,5-a]...)
Affinity DataKd:  8.90E+3nMAssay Description:Binding affinity to human wild type adenosine A2A receptor expressed in Expi293F cells assessed as dissociation constant by surface plasmon resonance...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetAdenosine receptor A2a(Human)
Neuroscience

LigandPNGBDBM50595377(Pteridine-2,4-Diamine | CHEMBL336555)
Affinity DataKd:  9.60E+3nMAssay Description:Binding affinity to human wild type adenosine A2A receptor expressed in Expi293F cells assessed as dissociation constant by surface plasmon resonance...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetAdenosine receptor A2a(Human)
Neuroscience

LigandPNGBDBM50083551(CHEMBL3423406)
Affinity DataKd:  1.00E+4nMAssay Description:Displacement of [3H]-ZM241385 from adenosine A2 receptor (unknown origin) expressed in sheep striatum membranes after 1.5 hrs by scintillation counti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2016
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Neuroscience

LigandPNGBDBM50083544(CHEMBL3423409)
Affinity DataKd:  1.10E+4nMAssay Description:Displacement of [3H]-ZM241385 from adenosine A2 receptor (unknown origin) expressed in sheep striatum membranes after 1.5 hrs by scintillation counti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2016
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Neuroscience

LigandPNGBDBM50595382(CHEMBL5208068)
Affinity DataKd:  1.35E+4nMAssay Description:Binding affinity to human wild type adenosine A2A receptor expressed in Expi293F cells assessed as dissociation constant by surface plasmon resonance...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetAdenosine receptor A2a(Human)
Neuroscience

LigandPNGBDBM50083560(CHEMBL3423400)
Affinity DataKd:  1.40E+4nMAssay Description:Displacement of [3H]-ZM241385 from adenosine A2 receptor (unknown origin) expressed in sheep striatum membranes after 1.5 hrs by scintillation counti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2016
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Neuroscience

LigandPNGBDBM50083559(CHEMBL3423401)
Affinity DataKd:  1.60E+4nMAssay Description:Displacement of [3H]-ZM241385 from adenosine A2 receptor (unknown origin) expressed in sheep striatum membranes after 1.5 hrs by scintillation counti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2016
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Neuroscience

LigandPNGBDBM50083554(CHEMBL3423405)
Affinity DataKd:  1.80E+4nMAssay Description:Displacement of [3H]-ZM241385 from adenosine A2 receptor (unknown origin) expressed in sheep striatum membranes after 1.5 hrs by scintillation counti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2016
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Neuroscience

LigandPNGBDBM50595381(CHEMBL5184937)
Affinity DataKd:  2.18E+4nMAssay Description:Binding affinity to human wild type adenosine A2A receptor expressed in Expi293F cells assessed as dissociation constant by surface plasmon resonance...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
Displayed 1 to 50 (of 71 total ) | Next | Last >>
Jump to: