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Report error Found 25 of ec50 for UniProtKB: P05177
TargetCytochrome P450 1A2(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50538668BDBM50538668(CHEMBL4634455 | US11518761, Example 159)
Affinity DataEC50:  460nMAssay Description:Inhibition of CYP1A2 in human liver microsomes using phenacetin as substrate measured after 10 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50577263BDBM50577263(CHEMBL4850236)
Affinity DataEC50:  1.90E+3nMAssay Description:Induction of CYP1A2 in human hepatocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 372346BDBM372346(US10245275, Example 2b | Method A: (R)-4-((1R,3aS,...)
Affinity DataEC50: >5.00E+3nMAssay Description:Induction of CYP1A2 in human hepatocyteMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetCytochrome P450 1A2(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50448495BDBM50448495(CHEMBL3126836)
Affinity DataEC50: >1.30E+4nMAssay Description:Inhibition of CYP1A2 in human liver microsomes after 30 mins in presence of NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50538670BDBM50538670(CHEMBL4642579)
Affinity DataEC50:  2.08E+4nMAssay Description:Inhibition of CYP1A2 in human liver microsomes using phenacetin as substrate measured after 10 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50114572BDBM50114572(CHEMBL3608916)
Affinity DataEC50:  2.39E+4nMAssay Description:Inhibition of human CYP1A2 by luminometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2016
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50348709BDBM50348709(CHEMBL1801062)
Affinity DataEC50:  3.50E+4nMAssay Description:Inhibition of human CYP1A2More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50448494BDBM50448494(CHEMBL3126657)
Affinity DataEC50: >4.00E+4nMAssay Description:Inhibition of CYP1A2 in human liver microsomes after 30 mins in presence of NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50448497BDBM50448497(CHEMBL3126834)
Affinity DataEC50: >4.00E+4nMAssay Description:Inhibition of CYP1A2 in human liver microsomes after 30 mins in presence of NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50448496BDBM50448496(CHEMBL3126835)
Affinity DataEC50: >4.00E+4nMAssay Description:Inhibition of CYP1A2 in human liver microsomes after 30 mins in presence of NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50451549BDBM50451549(CHEMBL4207737)
Affinity DataEC50: >5.00E+4nMAssay Description:Activation of CYP1A2 in human hepatocyte using phenacetin as substrate preincubated for 5 days followed by substrate addition and measured after 1 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetCytochrome P450 1A2(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50275432BDBM50275432(S-2-(6-(1,4-dihydrobenzo[d][1,2]dioxine-6-sulfonam...)
Affinity DataEC50: >5.00E+4nMAssay Description:Inhibition of CYP1A2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50249403BDBM50249403(CHEMBL4091821)
Affinity DataEC50: >5.00E+4nMAssay Description:Induction of CYP1A2 in cryopreserved human hepatocytes measured after 48 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2019
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50275377BDBM50275377(S-2-(6-(4-(3-(dimethylamino)propoxy)phenylsulfonam...)
Affinity DataEC50: >5.00E+4nMAssay Description:Inhibition of CYP1A2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50538669BDBM50538669(CHEMBL4646408)
Affinity DataEC50:  5.00E+4nMAssay Description:Inhibition of CYP1A2 in human liver microsomes using phenacetin as substrate measured after 10 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50114568BDBM50114568(CHEMBL3608913)
Affinity DataEC50:  7.88E+4nMAssay Description:Inhibition of human CYP1A2 by luminometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2016
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50437753BDBM50437753(CHEMBL2409564)
Affinity DataEC50: >1.00E+5nMAssay Description:Induction of CYP1A2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50348710BDBM50348710(CHEMBL1801506)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of human CYP1A2More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50114571BDBM50114571(CHEMBL3608915)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of human CYP1A2 by luminometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2016
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50348733BDBM50348733(CHEMBL1801060)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of human CYP1A2More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50114574BDBM50114574(CHEMBL3608921)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of human CYP1A2 by luminometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2016
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50246760BDBM50246760(CHEMBL4075348)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of CYP1A2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2019
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50114573BDBM50114573(CHEMBL3608920)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of human CYP1A2 by luminometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2016
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50566257BDBM50566257(CHEMBL4785210)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of CYP1A2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50348732BDBM50348732(CHEMBL1801504)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of human CYP1A2More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed