Found 2391 of ic50 data for polymerid = 240 
Affinity DataIC50: 0.00200nMAssay Description:Inhibition of human gamma secretase in HEK293 cells by reporter gene assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0150nMAssay Description:Inhibition of human gamma secretase assessed as amyloid-beta40 peptide production in HEK293 cells by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0200nMAssay Description:Inhibition of human gamma secretase assessed as amyloid-beta40 peptide production in HEK293 cells by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0240nMAssay Description:Inhibition of human gamma secretase in HEK293 cells by reporter gene assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0300nMAssay Description:Inhibition of gamma secretase in human SH-SY5Y cells by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0370nMAssay Description:Inhibition of human gamma secretase assessed as amyloid-beta40 peptide production in HEK293 cells by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0420nMAssay Description:Inhibition of human gamma secretase in HEK293 cells by reporter gene assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0500nMAssay Description:Inhibition of gamma secretase activity in human H4 cells transfected with APP695 mutant assessed as beta amyloid(1-40) production by whole cell assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0600nMAssay Description:Inhibition of gamma secretase in human SH-SY5Y cells by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0600nMAssay Description:Inhibition of gamma secretase in human SH-SY5Y cells by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0600nMAssay Description:Inhibition of gamma secretase in human SH-SY5Y cells by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0600nMAssay Description:Inhibition of gamma secretase in human SH-SY5Y cells by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0700nMAssay Description:Inhibition of gamma secretase in human SH-SY5Y cells by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0750nMAssay Description:Inhibition of human gamma secretase in HEK293 cells by reporter gene assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0800nMAssay Description:Inhibition of gamma secretase in human SH-SY5Y cells by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0800nMAssay Description:Inhibition of gamma secretase activity in human H4 cells transfected with APP695 mutant assessed as beta amyloid(1-40) production by whole cell assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0800nMAssay Description:Inhibition of gamma secretase in HEK293 cells expressing APP 695 assessed as reduction in amyloid beta levels after 5 hrs by Western blot analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0820nMAssay Description:Inhibition of gamma secretase in HEK293 cells assessed as reduction in amyloid beta40 level incubated for 4 hrs by electrochemiluminescence detection...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0900nMAssay Description:Inhibition of human gamma secretase assessed as amyloid-beta40 peptide production in HEK293 cells by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 0.100nMAssay Description:Inhibition of gamma secretase activity in human H4 cells transfected with APP695 mutant assessed as beta amyloid(1-40) production by whole cell assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.110nMAssay Description:Inhibition of gamma secretase activity in human H4 cells transfected with APP695 mutant assessed as beta amyloid(1-40) production by whole cell assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.120nMAssay Description:Inhibition of gamma secretase in human SH-SY5Y cells by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.130nMAssay Description:Inhibition of gamma-secretase in human IMR32 cell membrane using APP as substrate after 2 hrs by ELISAMore data for this Ligand-Target Pair
3D Structure (crystal)
Affinity DataIC50: 0.140nMAssay Description:Inhibition of gamma secretase activity in human H4 cells transfected with APP695 mutant assessed as beta amyloid(1-40) production by whole cell assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.150nMAssay Description:Inhibition of gamma secretase in human SH-SY5Y cells by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.170nMAssay Description:Inhibition of Gamma-secretase in human IMR-32 cells after 2 hrs by ELISA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.170nMAssay Description:Inhibition of gamma secretase in human SH-SY5Y cells by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.170nMAssay Description:Inhibition of Gamma-secretase in human IMR-32 cells after 2 hrs by ELISA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.178nMAssay Description:Inhibition of gamma secretase-mediated amyloid beta42 production in human H4 cells expressing human APP swedish mutantMore data for this Ligand-Target Pair
Affinity DataIC50: 0.178nMAssay Description:Inhibition of gamma-secretase (unknown origin) assessed as decrease in Abeta42 levelsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.190nMAssay Description:Inhibition of human gamma-secretase expressed in IMR32 cell membranes using MBPC-125 Swedish as substrate assessed as inhibition of amyloid beta40 pr...More data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:Inhibition of gamma secretase assessed as reduction of amyloid beta level in H4 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:Inhibition of Gamma-secretase in human IMR-32 cells after 2 hrs by ELISA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.210nMAssay Description:Inhibition of Gamma-secretase in human IMR-32 cells after 2 hrs by ELISA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.210nMAssay Description:Inhibition of human gamma secretase in HEK293 cells by reporter gene assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.210nMAssay Description:Inhibition of gamma secretase in human SH-SY5Y cells by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.220nMAssay Description:Inhibition of gamma secretase activity in human H4 cells transfected with APP695 mutant assessed as beta amyloid(1-40) production by whole cell assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.220nMAssay Description:Inhibition of gamma-secretase in human IMR32 cell membrane using APP as substrate after 2 hrs by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 0.220nMAssay Description:Inhibition of gamma secretase activity in human H4 cells transfected with APP695 mutant assessed as beta amyloid(1-40) production by whole cell assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.225nMAssay Description:Inhibition of gamma secretase-mediated amyloid beta42 production in human H4 cells expressing human APP swedish mutantMore data for this Ligand-Target Pair
Affinity DataIC50: 0.225nMAssay Description:Inhibition of gamma-secretase (unknown origin) assessed as decrease in Abeta42 levelsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.230nMAssay Description:Inhibition of human gamma secretase in H4 cells assessed as reduction of amyloid beta-40 levelsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.240nMAssay Description:Inhibition of gamma secretase in human SH-SY5Y cells by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.240nMAssay Description:Inhibition of Gamma-secretase in human IMR-32 cells after 2 hrs by ELISA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.260nMAssay Description:Inhibition of Gamma-secretase in human IMR-32 cells after 2 hrs by ELISA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.260nMAssay Description:Inhibition of Gamma-secretase in human IMR-32 cells after 2 hrs by ELISA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.260nMAssay Description:Inhibition of Gamma-secretase in human IMR-32 cells after 2 hrs by ELISA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.270nMAssay Description:Inhibition of gamma secretase (unknown origin) mediated Notch activationMore data for this Ligand-Target Pair
Affinity DataIC50: 0.270nMAssay Description:Inhibition of gamma-secretase in human H4-8Sw cells assessed as reduction in amyloid beta (1 to 42) formationMore data for this Ligand-Target Pair
Affinity DataIC50: 0.270nMAssay Description:Inhibition of gamma-secretase (unknown origin) assessed as inhibition of NICD cleavageMore data for this Ligand-Target Pair
