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TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
Georgetown University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50121212BDBM50121212(CHEMBL3622372)
Affinity DataEC50:  1.10nMAssay Description:Inhibition of human VPS34 assessed as reduction in PIP3 product complex formation measured after 30 mins in presence of ATP by quantitative PI3P ELIS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
Georgetown University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50121212BDBM50121212(CHEMBL3622372)
Affinity DataEC50:  1.20nMAssay Description:Inhibition of human VPS34 assessed as reduction in PIP3 product complex formationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
Georgetown University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 185147BDBM185147(BGT-226 | (Z)-but-2-enedioic acid;8-(6-methoxypyri...)
Affinity DataEC50:  7nMAssay Description:Inhibition of human VPS34 assessed as reduction in PIP3 product complex formation measured after 30 mins in presence of ATP by quantitative PI3P ELIS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
Georgetown University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50341209BDBM50341209(9-(6-aminopyridin-3-yl)-1-(3-(trifluoromethyl)phen...)
Affinity DataEC50:  8.60nMAssay Description:Inhibition of human VPS34 assessed as reduction in PIP3 product complex formationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
Georgetown University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50156294BDBM50156294(CHEMBL3781415)
Affinity DataEC50:  9.40nMAssay Description:Inhibition of human VPS34 assessed as reduction in PIP3 product complex formation measured after 30 mins in presence of ATP by quantitative PI3P ELIS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
Georgetown University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50341209BDBM50341209(9-(6-aminopyridin-3-yl)-1-(3-(trifluoromethyl)phen...)
Affinity DataEC50:  12nMAssay Description:Inhibition of human VPS34 assessed as reduction in PIP3 product complex formation measured after 30 mins in presence of ATP by quantitative PI3P ELIS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
Georgetown University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50156294BDBM50156294(CHEMBL3781415)
Affinity DataEC50:  18nMAssay Description:Inhibition of human VPS34 assessed as reduction in PIP3 product complex formationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
Georgetown University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50042924BDBM50042924(CHEMBL1229535)
Affinity DataEC50:  220nMAssay Description:Inhibition of human VPS34 assessed as reduction in PIP3 product complex formation measured after 30 mins in presence of ATP by quantitative PI3P ELIS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
Georgetown University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50042924BDBM50042924(CHEMBL1229535)
Affinity DataEC50:  307nMAssay Description:Inhibition of human VPS34 assessed as reduction in PIP3 product complex formationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
Georgetown University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50145416BDBM50145416(GSK2126458 | Omipalisib)
Affinity DataEC50:  364nMAssay Description:Inhibition of human VPS34 assessed as reduction in PIP3 product complex formation measured after 30 mins in presence of ATP by quantitative PI3P ELIS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
Georgetown University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653061BDBM50653061(CHEMBL5723005)
Affinity DataEC50:  533nMAssay Description:Inhibition of human VPS34 assessed as reduction in PIP3 product complex formationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
Georgetown University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653061BDBM50653061(CHEMBL5723005)
Affinity DataEC50:  784nMAssay Description:Inhibition of human VPS34 assessed as reduction in PIP3 product complex formation measured after 30 mins in presence of ATP by quantitative PI3P ELIS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
Georgetown University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 315499BDBM315499(US10172858, Table 1.22)
Affinity DataEC50: >1.00E+3nMAssay Description:Inhibition of human VPS34 assessed as reduction in PIP3 product complex formationMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
Georgetown University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 315499BDBM315499(US10172858, Table 1.22)
Affinity DataEC50:  5.62E+3nMAssay Description:Inhibition of human VPS34 assessed as reduction in PIP3 product complex formation measured after 30 mins in presence of ATP by quantitative PI3P ELIS...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed