Compile Data Set for Download or QSAR
Report error Found 1893 of ic50 for UniProtKB: Q8NEB9
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50156294BDBM50156294(CHEMBL3781415)
Affinity DataIC50: 0.0180nMAssay Description:Inhibition of Vps34 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50612802BDBM50612802(CHEMBL273832 | 17-hydroxywortmannin)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of VPS34 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 528011BDBM528011(US11179399, Example 44_1)
Affinity DataIC50: 1nMAssay Description:Dilution series of compounds of the invention were prepared in DMSO at 100 times the final assay concentration (n1=n0/3 in 10 points). The compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2022
Entry Details
US Patent

TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50121212BDBM50121212(CHEMBL3622372)
Affinity DataIC50: 1nMAssay Description:Inhibition of human PIK3C3 using PI as substrate by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50121212BDBM50121212(CHEMBL3622372)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of Vps34 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50121212BDBM50121212(CHEMBL3622372)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of Vps34 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/14/2018
Entry Details Article
PubMed
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50121212BDBM50121212(CHEMBL3622372)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of recombinant human Vps34 by TR-FRET analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2016
Entry Details Article
PubMed
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50121212BDBM50121212(CHEMBL3622372)
Affinity DataIC50: 1.20nMAssay Description:Competitive inhibition of recombinant human VPS34 in presence of ATP by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50506332BDBM50506332(CHEMBL4561242)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of VPS34 in human HL60 cell extract measured after 2 hrs by kinobeads based pull down assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50597817BDBM50597817(CHEMBL5192406)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of human wild type N-terminal GST tagged VPS34 (1 to 887 end) expressed in baculovirus infected Sf21 insect cells using PI and Phosphatidy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50503132BDBM50503132(CHEMBL4586628)
Affinity DataIC50: 2nMAssay Description:Inhibition of Vps34 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 527982BDBM527982(US11179399, Example 25_1)
Affinity DataIC50: 2nMAssay Description:Dilution series of compounds of the invention were prepared in DMSO at 100 times the final assay concentration (n1=n0/3 in 10 points). The compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2022
Entry Details
US Patent

TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50503142BDBM50503142(CHEMBL4517404)
Affinity DataIC50: 2nMAssay Description:Inhibition of Vps34 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50357652BDBM50357652(CHEMBL1914726)
Affinity DataIC50: 2.90nMAssay Description:Inhibition of human VPS34 assessed as ADP formation using ATP by fluorescence-based immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 528009BDBM528009(US11179399, Example 43_1)
Affinity DataIC50: 3nMAssay Description:Dilution series of compounds of the invention were prepared in DMSO at 100 times the final assay concentration (n1=n0/3 in 10 points). The compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2022
Entry Details
US Patent

TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50597812BDBM50597812(CHEMBL5192215)
Affinity DataIC50: 3nMAssay Description:Inhibition of human wild type N-terminal GST tagged VPS34 (1 to 887 end) expressed in baculovirus infected Sf21 insect cells using PI and Phosphatidy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 528013BDBM528013(6-[4-acetyl-2-(trifluoromethyl)piperazin-1-yl]-4-[...)
Affinity DataIC50: 3nMAssay Description:Dilution series of compounds of the invention were prepared in DMSO at 100 times the final assay concentration (n1=n0/3 in 10 points). The compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2022
Entry Details
US Patent

TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50503135BDBM50503135(CHEMBL4536755)
Affinity DataIC50: 3nMAssay Description:Inhibition of Vps34 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50506327BDBM50506327(CHEMBL4449047)
Affinity DataIC50: 3.20nMAssay Description:Inhibition of VPS34 in human HL60 cell extract measured after 2 hrs by kinobeads based pull down assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 31767BDBM31767(3-(4-morpholinopyrido[2,3]furo[2,4-b]pyrimidin-2-y...)
Affinity DataIC50: 4nMAssay Description:Inhibition of human recombinant PI3K Vsp34 in the presence of ATP by scintillation proximity radiometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 527981BDBM527981((R) and (S) 4-[(3R)-3-methylmorpholin-4-yl]-6-[2-(...)
Affinity DataIC50: 4nMAssay Description:Dilution series of compounds of the invention were prepared in DMSO at 100 times the final assay concentration (n1=n0/3 in 10 points). The compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2022
Entry Details
US Patent

TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 527937BDBM527937(6-[2-(3-methoxyphenyl)pyrrolidin-1-yl]-4-(3-methyl...)
Affinity DataIC50: 4nMAssay Description:Dilution series of compounds of the invention were prepared in DMSO at 100 times the final assay concentration (n1=n0/3 in 10 points). The compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2022
Entry Details
US Patent

TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 15234BDBM15234(NSC221019 | Wortmannin, Wm | cid_312145 | CHEMBL42...)
Affinity DataIC50: 4.20nMAssay Description:Inhibition of VPS34 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 532279BDBM532279(6-[1-Ethyl-3-(trifluoromethyl)pyrazol-4-yl]-4-[2-[...)
Affinity DataIC50: 5nMAssay Description:Dilution series of compounds of the invention were prepared in DMSO at 100 times the final assay concentration (n1=n0/3 in 10 points). The compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2023
Entry Details
US Patent

TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 532281BDBM532281(6-(2-Chlorophenyl)-4-[2-[(2-methylpyrimidin-4-yl)a...)
Affinity DataIC50: 5nMAssay Description:Dilution series of compounds of the invention were prepared in DMSO at 100 times the final assay concentration (n1=n0/3 in 10 points). The compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2023
Entry Details
US Patent

TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 532277BDBM532277(6-(4-Methyl-3-pyridyl)-4-[2-[(2-methylpyrimidin-4-...)
Affinity DataIC50: 5nMAssay Description:Dilution series of compounds of the invention were prepared in DMSO at 100 times the final assay concentration (n1=n0/3 in 10 points). The compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2023
Entry Details
US Patent

TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 532278BDBM532278(4-[2-[(2-Methylpyrimidin-4-yl)amino]-4-pyridyl]-6-...)
Affinity DataIC50: 5nMAssay Description:Dilution series of compounds of the invention were prepared in DMSO at 100 times the final assay concentration (n1=n0/3 in 10 points). The compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2023
Entry Details
US Patent

TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 532263BDBM532263(4-(2-Anilinopyrimidin-4-yl)-6-(3-pyridyl)-1H-pyrid...)
Affinity DataIC50: 5nMAssay Description:Dilution series of compounds of the invention were prepared in DMSO at 100 times the final assay concentration (n1=n0/3 in 10 points). The compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2023
Entry Details
US Patent

TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 532265BDBM532265(4-(2-anilinopyrimidin-4-yl)-6-morpholino-1H-pyridi...)
Affinity DataIC50: 5nMAssay Description:Dilution series of compounds of the invention were prepared in DMSO at 100 times the final assay concentration (n1=n0/3 in 10 points). The compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2023
Entry Details
US Patent

TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 532266BDBM532266(4-[2-[(2-Methylpyrimidin-4-yl)amino]-4-pyridyl]-6-...)
Affinity DataIC50: 5nMAssay Description:Dilution series of compounds of the invention were prepared in DMSO at 100 times the final assay concentration (n1=n0/3 in 10 points). The compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2023
Entry Details
US Patent

TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 532262BDBM532262(4-(2-anilinopyrimidin-4-yl)-6-(2-chlorophenyl)-1H-...)
Affinity DataIC50: 5nMAssay Description:Dilution series of compounds of the invention were prepared in DMSO at 100 times the final assay concentration (n1=n0/3 in 10 points). The compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2023
Entry Details
US Patent

TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 532271BDBM532271(6-[4-Ethylsulfonyl-2-(trifluoromethyl)piperazin-1-...)
Affinity DataIC50: 5nMAssay Description:Dilution series of compounds of the invention were prepared in DMSO at 100 times the final assay concentration (n1=n0/3 in 10 points). The compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2023
Entry Details
US Patent

TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 532272BDBM532272(4-[2-(Oxazol-2-ylamino)-4-pyridyl]-6-[3-(trifluoro...)
Affinity DataIC50: 5nMAssay Description:Dilution series of compounds of the invention were prepared in DMSO at 100 times the final assay concentration (n1=n0/3 in 10 points). The compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2023
Entry Details
US Patent

TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 532274BDBM532274(4-[2-[(2-Methylpyrimidin-4-yl)amino]-4-pyridyl]-6-...)
Affinity DataIC50: 5nMAssay Description:Dilution series of compounds of the invention were prepared in DMSO at 100 times the final assay concentration (n1=n0/3 in 10 points). The compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2023
Entry Details
US Patent

TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 532267BDBM532267(4-(2-Anilinopyrimidin-4-yl)-6-[2-(trifluoromethyl)...)
Affinity DataIC50: 5nMAssay Description:Dilution series of compounds of the invention were prepared in DMSO at 100 times the final assay concentration (n1=n0/3 in 10 points). The compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2023
Entry Details
US Patent

TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 532268BDBM532268(4-[2-[(2-Methylpyrimidin-4-yl)amino]-4-pyridyl]-6-...)
Affinity DataIC50: 5nMAssay Description:Dilution series of compounds of the invention were prepared in DMSO at 100 times the final assay concentration (n1=n0/3 in 10 points). The compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2023
Entry Details
US Patent

TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 532269BDBM532269(4-(2-Anilinopyrimidin-4-yl)-6-[3-(trifluoromethyl)...)
Affinity DataIC50: 5nMAssay Description:Dilution series of compounds of the invention were prepared in DMSO at 100 times the final assay concentration (n1=n0/3 in 10 points). The compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2023
Entry Details
US Patent

TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 532270BDBM532270(6-[4-[(4-Fluorophenyl)methylsulfonyl]-2-(trifluoro...)
Affinity DataIC50: 5nMAssay Description:Dilution series of compounds of the invention were prepared in DMSO at 100 times the final assay concentration (n1=n0/3 in 10 points). The compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2023
Entry Details
US Patent

TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 532271BDBM532271(6-[4-Ethylsulfonyl-2-(trifluoromethyl)piperazin-1-...)
Affinity DataIC50: 5nMAssay Description:Dilution series of compounds of the invention were prepared in DMSO at 100 times the final assay concentration (n1=n0/3 in 10 points). The compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2022
Entry Details
US Patent

TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 532270BDBM532270(6-[4-[(4-Fluorophenyl)methylsulfonyl]-2-(trifluoro...)
Affinity DataIC50: 5nMAssay Description:Dilution series of compounds of the invention were prepared in DMSO at 100 times the final assay concentration (n1=n0/3 in 10 points). The compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2022
Entry Details
US Patent

TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 532272BDBM532272(4-[2-(Oxazol-2-ylamino)-4-pyridyl]-6-[3-(trifluoro...)
Affinity DataIC50: 5nMAssay Description:Dilution series of compounds of the invention were prepared in DMSO at 100 times the final assay concentration (n1=n0/3 in 10 points). The compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2022
Entry Details
US Patent

TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 532274BDBM532274(4-[2-[(2-Methylpyrimidin-4-yl)amino]-4-pyridyl]-6-...)
Affinity DataIC50: 5nMAssay Description:Dilution series of compounds of the invention were prepared in DMSO at 100 times the final assay concentration (n1=n0/3 in 10 points). The compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2022
Entry Details
US Patent

TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 532277BDBM532277(6-(4-Methyl-3-pyridyl)-4-[2-[(2-methylpyrimidin-4-...)
Affinity DataIC50: 5nMAssay Description:Dilution series of compounds of the invention were prepared in DMSO at 100 times the final assay concentration (n1=n0/3 in 10 points). The compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2022
Entry Details
US Patent

TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 532279BDBM532279(6-[1-Ethyl-3-(trifluoromethyl)pyrazol-4-yl]-4-[2-[...)
Affinity DataIC50: 5nMAssay Description:Dilution series of compounds of the invention were prepared in DMSO at 100 times the final assay concentration (n1=n0/3 in 10 points). The compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2022
Entry Details
US Patent

TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 532278BDBM532278(4-[2-[(2-Methylpyrimidin-4-yl)amino]-4-pyridyl]-6-...)
Affinity DataIC50: 5nMAssay Description:Dilution series of compounds of the invention were prepared in DMSO at 100 times the final assay concentration (n1=n0/3 in 10 points). The compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2022
Entry Details
US Patent

TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 532281BDBM532281(6-(2-Chlorophenyl)-4-[2-[(2-methylpyrimidin-4-yl)a...)
Affinity DataIC50: 5nMAssay Description:Dilution series of compounds of the invention were prepared in DMSO at 100 times the final assay concentration (n1=n0/3 in 10 points). The compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2022
Entry Details
US Patent

TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 590174BDBM590174(US11560374, Example 6-1)
Affinity DataIC50: 5nMAssay Description:Dilution series of compounds of the invention were prepared in DMSO at 100 times the final assay concentration (n1=n0/3 in 10 points). The compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
US Patent

TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 580120BDBM580120(US11498919, Example 4 | 4-(1H-pyrrolo[2,3-b]pyridi...)
Affinity DataIC50: 5nMAssay Description:Dilution series of compounds of the invention were prepared in DMSO at 100 times the final assay concentration (n1=n0/3 in 10 points). The compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2023
Entry Details
US Patent

TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 532955BDBM532955(US11219618, Example 1 | N-[4-[2-(2-chlorophenyl)-6...)
Affinity DataIC50: 5nMAssay Description:Dilution series of compounds of the invention were prepared in DMSO at 100 times the final assay concentration (n1=n0/3 in 10 points). The compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2022
Entry Details
US Patent

TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 532263BDBM532263(4-(2-Anilinopyrimidin-4-yl)-6-(3-pyridyl)-1H-pyrid...)
Affinity DataIC50: 5nMAssay Description:Dilution series of compounds of the invention were prepared in DMSO at 100 times the final assay concentration (n1=n0/3 in 10 points). The compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2022
Entry Details
US Patent

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