Compile Data Set for Download or QSAR
Report error Found 35 of kd for UniProtKB: Q8NEB9
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50610495BDBM50610495(CHEMBL5286775)
Affinity DataKd:  0.530nMAssay Description:Binding affinity to VPS34 (unknown origin) assessed as dissociation constant by KINOMEscan analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50610495BDBM50610495(CHEMBL5286775)
Affinity DataKd:  0.530nMAssay Description:Inhibition of PIK3C3 (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 527983BDBM527983(US11179399, Example 25_2)
Affinity DataKd:  1nMAssay Description:Binding affinity to VPS34 (unknown origin) assessed as dissociation constant by KINOMEscan analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50059640BDBM50059640(CHEMBL2140173)
Affinity DataKd:  1.70nMAssay Description:Binding affinity to human Vps34 expressed in mammalian expression systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50550669BDBM50550669(CHEMBL4794132)
Affinity DataKd:  2nMAssay Description:Binding affinity to human Vps34 expressed in mammalian expression systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50506323BDBM50506323(CHEMBL4556087)
Affinity DataKd:  2nMAssay Description:Binding affinity to VPS34 in human HL60 cell extract measured after 2 hrs by kinobeads based pull down assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50550684BDBM50550684(CHEMBL4752634)
Affinity DataKd:  4nMAssay Description:Binding affinity to human Vps34 expressed in mammalian expression systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50550657BDBM50550657(CHEMBL4792737)
Affinity DataKd:  5.10nMAssay Description:Binding affinity to human Vps34 expressed in mammalian expression systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50632898BDBM50632898(CHEMBL5416758)
Affinity DataKd:  20nMAssay Description:Binding affinity to VPS34 (unknown origin) assessed as dissociation constant by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50559197BDBM50559197(CHEMBL4741511)
Affinity DataKd:  28nMAssay Description:Binding affinity to wild-type human partial length VPS34 (S282 to H879 residues) expressed in HEK293 cells measured after 1 hr by Kinomescan methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50506315BDBM50506315(CHEMBL4579923)
Affinity DataKd:  63nMAssay Description:Binding affinity to VPS34 in human HL60 cell extract measured after 2 hrs by kinobeads based pull down assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50559193BDBM50559193(CHEMBL4749352)
Affinity DataKd:  65nMAssay Description:Binding affinity to wild-type human partial length VPS34 (S282 to H879 residues) expressed in HEK293 cells measured after 1 hr by Kinomescan methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50632896BDBM50632896(CHEMBL5434183)
Affinity DataKd:  68nMAssay Description:Binding affinity to VPS34 (unknown origin) assessed as dissociation constant by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50240973BDBM50240973(CHEMBL4102855)
Affinity DataKd:  130nMAssay Description:Binding affinity to human VPS34 (S282 to H879 residues) expressed in mammalian expression system by Kinomescan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2019
Entry Details Article
PubMed
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50380363BDBM50380363(CHEMBL2017974 | US10173995, Compound 1)
Affinity DataKd:  200nMAssay Description:Binding affinity to human VPS34 (S282 to H879 residues) expressed in mammalian expression system by Kinomescan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2019
Entry Details Article
PubMed
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50240975BDBM50240975(CHEMBL4084907)
Affinity DataKd:  230nMAssay Description:Binding affinity to human VPS34 (S282 to H879 residues) expressed in mammalian expression system by Kinomescan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2019
Entry Details Article
PubMed
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50358204BDBM50358204(CHEMBL1922094)
Affinity DataKd:  250nMAssay Description:Binding affinity to human VPS34 (S282 to H879 residues) expressed in mammalian expression system by Kinomescan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2019
Entry Details Article
PubMed
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50537996BDBM50537996(CHEMBL4632827)
Affinity DataKd:  410nMAssay Description:Binding affinity to wild-type human partial length PIK3C3 (S282 to H879 residues) expressed in mammalian expression system at 10 uM by Kinomescan met...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50505407BDBM50505407(CHEMBL4436124)
Affinity DataKd:  980nMAssay Description:Binding affinity to human wild-type partial length VPS34 (S282 to H879 residues) expressed in mammalian expression system by kinome scan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50632905BDBM50632905(CHEMBL5414359)
Affinity DataKd:  1.80E+3nMAssay Description:Binding affinity to VPS34 (unknown origin) assessed as dissociation constant by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50505414BDBM50505414(CHEMBL4594206)
Affinity DataKd:  2.10E+3nMAssay Description:Binding affinity to human wild-type partial length VPS34 (S282 to H879 residues) expressed in mammalian expression system by kinome scan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50092783BDBM50092783(CHEMBL3586404)
Affinity DataKd:  2.50E+3nMAssay Description:Inhibition of human VPS34 (282 to 879 residues) expressed in mammalian expression system by KINOMEscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2020
Entry Details Article
PubMed
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50469457BDBM50469457(CHEMBL4286698)
Affinity DataKd:  2.75E+3nMAssay Description:Inhibition of human VPS34 (282 to 879 residues) expressed in mammalian expression system by KINOMEscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2020
Entry Details Article
PubMed
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50469457BDBM50469457(CHEMBL4286698)
Affinity DataKd:  2.75E+3nMAssay Description:Binding affinity to human wild-type partial length VPS34 (S282 to H879 residues) expressed in mammalian expression system by kinome scan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50632897BDBM50632897(CHEMBL5425043)
Affinity DataKd:  2.90E+3nMAssay Description:Binding affinity to VPS34 (unknown origin) assessed as dissociation constant by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50505410BDBM50505410(CHEMBL4551080)
Affinity DataKd:  3.20E+3nMAssay Description:Binding affinity to human wild-type partial length VPS34 (S282 to H879 residues) expressed in mammalian expression system by kinome scan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50632918BDBM50632918(CHEMBL5396725)
Affinity DataKd:  4.20E+3nMAssay Description:Binding affinity to VPS34 (unknown origin) assessed as dissociation constant by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50308135BDBM50308135(PKI-587 | 1-(4-{[4-(Dimethylamino)piperidin-1-yl]c...)
Affinity DataKd:  5.10E+3nMAssay Description:Binding affinity to human VPS34 (S282 to H879 residues) expressed in mammalian expression system by Kinomescan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2019
Entry Details Article
PubMed
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50617437BDBM50617437(CHEMBL5400572)
Affinity DataKd:  6.10E+3nMAssay Description:Binding affinity to DNA-tagged VPS34 (unknown origin) assessed as dissociation constant by quantitative PCR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 315477BDBM315477(US10172858, Table 1.22 | US10172858, Table 1.1)
Affinity DataKd:  8.20E+3nMAssay Description:Inhibition of human VPS34 (282 to 879 residues) expressed in mammalian expression system by KINOMEscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2020
Entry Details Article
PubMed
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50469458BDBM50469458(CHEMBL4279703)
Affinity DataKd:  8.30E+3nMAssay Description:Inhibition of human VPS34 (282 to 879 residues) expressed in mammalian expression system by KINOMEscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2020
Entry Details Article
PubMed
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50571459BDBM50571459(CHEMBL4872830)
Affinity DataKd:  1.10E+4nMAssay Description:Binding affinity to VPS34 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50637408BDBM50637408(CHEMBL1161626)
Affinity DataKd:  1.20E+4nMAssay Description:Binding affinity to Vps34 (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50429701BDBM50429701(AZD-2014 | CHEMBL2336325 | US9102670, 1ap)
Affinity DataKd:  2.30E+4nMAssay Description:Inhibition of human VPS34 (282 to 879 residues) expressed in mammalian expression system by KINOMEscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2020
Entry Details Article
PubMed
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50652793BDBM50652793(CHEMBL5653589)
Affinity DataKd:  2.60E+4nMAssay Description:Binding affinity to human PIK3C3 incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed