Compile Data Set for Download or QSAR
Report error Found 81 of kd for UniProtKB: P00734
TargetProthrombin(Human)
Gunma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50481926BDBM50481926(CHEMBL1077162)
Affinity DataKd:  0.180nMAssay Description:Binding affinity to human thrombin after 30 mins by non-equilibrium capillary electrophoresisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetProthrombin(Human)
Gunma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50481924BDBM50481924(CHEMBL1077164)
Affinity DataKd:  0.210nMAssay Description:Binding affinity to human thrombin after 30 mins by non-equilibrium capillary electrophoresisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetProthrombin(Human)
Gunma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50481927BDBM50481927(CHEMBL1077161)
Affinity DataKd:  0.25nMAssay Description:Binding affinity to human thrombin after 30 mins by non-equilibrium capillary electrophoresisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetProthrombin(Human)
Gunma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50481925BDBM50481925(CHEMBL1077163)
Affinity DataKd:  0.270nMAssay Description:Binding affinity to human thrombin after 30 mins by non-equilibrium capillary electrophoresisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetProthrombin(Human)
Gunma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50442881BDBM50442881(SILYBIN A)
Affinity DataKd:  1.90nMAssay Description:Inhibition of human thrombin assessed as equilibrium dissociation constant at 50 to 1000 uM by BIAcore analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2014
Entry Details Article
PubMed
TargetProthrombin(Human)
Gunma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50241503BDBM50241503(CHEMBL404515 | CHEMBL511367 | 2-(3,4-dihydroxyphen...)
Affinity DataKd:  7.80nMAssay Description:Inhibition of human thrombin assessed as equilibrium dissociation constant at 50 to 1000 uM by BIAcore analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2014
Entry Details Article
PubMed
TargetProthrombin(Human)
Gunma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50350701BDBM50350701(CHEMBL1814826)
Affinity DataKd:  37nMAssay Description:Binding affinity to thrombin at 37 degC by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Gunma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 7460BDBM7460(2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-chromone;...)
Affinity DataKd:  38.7nMAssay Description:Inhibition of human thrombin assessed as equilibrium dissociation constant at 50 to 1000 uM by BIAcore analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2014
Entry Details Article
PubMed
TargetProthrombin(Human)
Gunma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50350695BDBM50350695(CHEMBL1814697)
Affinity DataKd:  47.6nMAssay Description:Binding affinity to thrombin at 37 degC by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Gunma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50350697BDBM50350697(CHEMBL1814820)
Affinity DataKd:  52.6nMAssay Description:Binding affinity to thrombin at 37 degC by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Gunma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50511169BDBM50511169(CHEMBL4551377)
Affinity DataKd:  100nMAssay Description:Binding affinity to human alpha-thrombin in phosphate/HEPES/Tricine/Tris buffer by ITC methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProthrombin(Human)
Gunma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50307871BDBM50307871((S)-1-((R)-2-aminobutanoyl)-N-(4-carbamimidoylbenz...)
Affinity DataKd:  110nMAssay Description:Binding affinity to thrombin (unknown origin) by direct isothermal titration colorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2016
Entry Details Article
PubMed
TargetProthrombin(Human)
Gunma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50115492BDBM50115492(CHEMBL3608989)
Affinity DataKd:  160nMAssay Description:Binding affinity to thrombin (unknown origin) by direct isothermal titration colorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProthrombin(Human)
Gunma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50392032BDBM50392032(CHEMBL2152432)
Affinity DataKd:  232nMAssay Description:Inhibition of human thrombin by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetProthrombin(Human)
Gunma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50392033BDBM50392033(CHEMBL2152433)
Affinity DataKd:  255nMAssay Description:Inhibition of human thrombin by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProthrombin(Human)
Gunma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50115491BDBM50115491(CHEMBL3608988)
Affinity DataKd:  270nMAssay Description:Binding affinity to thrombin (unknown origin) by direct isothermal titration colorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2016
Entry Details Article
PubMed
TargetProthrombin(Human)
Gunma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 29379BDBM29379(proline scaffold, 28)
Affinity DataIC50: 1.60E+3nM Kd:  270nMAssay Description:SPR experiments where performed with a Biacore A100 using Series S sensor chip CM5 (GE Healthcare Bio-Sciences AB, Uppsala, Sweden). The proteins wer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Gunma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50350699BDBM50350699(CHEMBL1814822)
Affinity DataKd:  300nMAssay Description:Binding affinity to thrombin at 37 degC by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Gunma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50378698BDBM50378698(CHEMBL1078314)
Affinity DataKd:  320nMAssay Description:Binding affinity to thrombin by surface plasmon resonance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Gunma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50378698BDBM50378698(CHEMBL1078314)
Affinity DataKd:  390nMAssay Description:Binding affinity to thrombin in presence of 100 mJ/cm'2 UV light by surface plasmon resonance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Gunma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50511166BDBM50511166(CHEMBL4513436)
Affinity DataKd:  400nMAssay Description:Binding affinity to human alpha-thrombin in phosphate/HEPES/Tricine/Tris buffer by ITC methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProthrombin(Human)
Gunma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50125842BDBM50125842(5-amino(imino)methylamino-2-[1-[2-amino-3-phenyl-(...)
Affinity DataKd:  575nMAssay Description:Binding affinity against thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetProthrombin(Human)
Gunma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50511167BDBM50511167(CHEMBL4563187)
Affinity DataKd:  916nMAssay Description:Binding affinity to human alpha-thrombin in phosphate/HEPES/Tricine/Tris buffer by ITC methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProthrombin(Human)
Gunma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50455289BDBM50455289(CHEMBL4212514)
Affinity DataKd:  1.00E+3nMAssay Description:Binding affinity to human fluorescence labelled FPRCK-alpha thrombin by fluorimetric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetProthrombin(Human)
Gunma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50350698BDBM50350698(CHEMBL1814696)
Affinity DataKd:  1.00E+3nMAssay Description:Binding affinity to thrombin at 37 degC by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Gunma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 29383BDBM29383(proline scaffold, 32)
Affinity DataIC50: 4.20E+3nM Kd:  1.10E+3nMAssay Description:SPR experiments where performed with a Biacore A100 using Series S sensor chip CM5 (GE Healthcare Bio-Sciences AB, Uppsala, Sweden). The proteins wer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Gunma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50350700BDBM50350700(CHEMBL1814823)
Affinity DataKd:  1.30E+3nMAssay Description:Binding affinity to thrombin at 37 degC by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Gunma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50350702BDBM50350702(CHEMBL1814824)
Affinity DataKd:  1.50E+3nMAssay Description:Binding affinity to thrombin at 37 degC by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Gunma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50350696BDBM50350696(CHEMBL1814819)
Affinity DataKd:  1.60E+3nMAssay Description:Binding affinity to thrombin at 37 degC by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Gunma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 29375BDBM29375(proline scaffold, 24)
Affinity DataIC50: 1.30E+4nM Kd:  2.20E+3nMpH: 7.4 T: 2°CAssay Description:SPR experiments where performed with a Biacore A100 using Series S sensor chip CM5 (GE Healthcare Bio-Sciences AB, Uppsala, Sweden). The proteins wer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Gunma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50455284BDBM50455284(CHEMBL4210645)
Affinity DataKd:  2.80E+3nMAssay Description:Binding affinity to wild-type thrombin (unknown origin) by intrinsic fluorescence methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetProthrombin(Human)
Gunma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 29377BDBM29377(proline scaffold, 26)
Affinity DataIC50: 1.80E+4nM Kd:  3.10E+3nMAssay Description:SPR experiments where performed with a Biacore A100 using Series S sensor chip CM5 (GE Healthcare Bio-Sciences AB, Uppsala, Sweden). The proteins wer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Gunma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50511168BDBM50511168(CHEMBL4465587)
Affinity DataKd:  3.68E+3nMAssay Description:Binding affinity to human alpha-thrombin in phosphate/HEPES/Tricine/Tris buffer by ITC methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProthrombin(Human)
Gunma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50455284BDBM50455284(CHEMBL4210645)
Affinity DataKd:  3.70E+3nMAssay Description:Binding affinity to human fluorescence labelled FPRCK-alpha thrombin by fluorimetric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetProthrombin(Human)
Gunma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 29378BDBM29378(proline scaffold, 27)
Affinity DataIC50: 8.90E+4nM Kd:  6.80E+3nMAssay Description:SPR experiments where performed with a Biacore A100 using Series S sensor chip CM5 (GE Healthcare Bio-Sciences AB, Uppsala, Sweden). The proteins wer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Gunma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 29385BDBM29385(proline scaffold, 34)
Affinity DataIC50: 2.00E+4nM Kd:  9.00E+3nMAssay Description:SPR experiments where performed with a Biacore A100 using Series S sensor chip CM5 (GE Healthcare Bio-Sciences AB, Uppsala, Sweden). The proteins wer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Gunma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 29367BDBM29367(proline scaffold, 16)
Affinity DataIC50: 4.90E+4nM Kd:  2.30E+4nMpH: 7.4 T: 2°CAssay Description:SPR experiments where performed with a Biacore A100 using Series S sensor chip CM5 (GE Healthcare Bio-Sciences AB, Uppsala, Sweden). The proteins wer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Gunma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 29381BDBM29381(proline scaffold, 30)
Affinity DataIC50: 1.20E+5nM Kd:  2.70E+4nMAssay Description:SPR experiments where performed with a Biacore A100 using Series S sensor chip CM5 (GE Healthcare Bio-Sciences AB, Uppsala, Sweden). The proteins wer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Gunma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 29359BDBM29359(proline scaffold, 8)
Affinity DataIC50: 1.20E+5nM Kd:  3.40E+4nMpH: 7.4 T: 2°CAssay Description:SPR experiments where performed with a Biacore A100 using Series S sensor chip CM5 (GE Healthcare Bio-Sciences AB, Uppsala, Sweden). The proteins wer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Gunma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 29386BDBM29386(proline scaffold, 35)
Affinity DataIC50: 1.70E+5nM Kd:  3.50E+4nMAssay Description:SPR experiments where performed with a Biacore A100 using Series S sensor chip CM5 (GE Healthcare Bio-Sciences AB, Uppsala, Sweden). The proteins wer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Gunma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 29376BDBM29376(proline scaffold, 25)
Affinity DataIC50: 2.30E+5nM Kd:  3.80E+4nMpH: 7.4 T: 2°CAssay Description:SPR experiments where performed with a Biacore A100 using Series S sensor chip CM5 (GE Healthcare Bio-Sciences AB, Uppsala, Sweden). The proteins wer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Gunma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 29373BDBM29373(proline scaffold, 22)
Affinity DataIC50: 2.10E+5nM Kd:  4.50E+4nMpH: 7.4 T: 2°CAssay Description:SPR experiments where performed with a Biacore A100 using Series S sensor chip CM5 (GE Healthcare Bio-Sciences AB, Uppsala, Sweden). The proteins wer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Gunma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 29384BDBM29384(proline scaffold, 33)
Affinity DataIC50: 2.30E+5nM Kd:  4.90E+4nMAssay Description:SPR experiments where performed with a Biacore A100 using Series S sensor chip CM5 (GE Healthcare Bio-Sciences AB, Uppsala, Sweden). The proteins wer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Gunma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 23416BDBM23416((+)-Catechin | CHEMBL311498 | (2R,3S)-2-(3,4-dihyd...)
Affinity DataKd:  4.92E+4nMAssay Description:Inhibition of human thrombin assessed as equilibrium dissociation constant at 50 to 1000 uM by BIAcore analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2014
Entry Details Article
PubMed
TargetProthrombin(Human)
Gunma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50092660BDBM50092660(CHEMBL545184 | p-aminobenzamidine | 4-Amino-benzam...)
Affinity DataKd:  7.80E+4nMAssay Description:Binding affinity to human alpha thrombin by Biocore A100 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetProthrombin(Human)
Gunma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50387180BDBM50387180(CHEMBL2047998)
Affinity DataKd:  9.50E+4nMAssay Description:Binding affinity to human alpha thrombin by Biocore A100 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetProthrombin(Human)
Gunma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 29365BDBM29365(proline scaffold, 14)
Affinity DataIC50: 3.80E+5nM Kd:  9.90E+4nMpH: 7.4 T: 2°CAssay Description:SPR experiments where performed with a Biacore A100 using Series S sensor chip CM5 (GE Healthcare Bio-Sciences AB, Uppsala, Sweden). The proteins wer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Gunma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50037981BDBM50037981(CHEMBL103102 | CHEMBL216318 | Piperidine-1-carboxa...)
Affinity DataKd:  1.07E+5nMAssay Description:Binding affinity to thrombin (unknown origin) by direct isothermal titration colorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProthrombin(Human)
Gunma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 29382BDBM29382(proline scaffold, 31)
Affinity DataIC50: 4.00E+5nM Kd:  1.10E+5nMAssay Description:SPR experiments where performed with a Biacore A100 using Series S sensor chip CM5 (GE Healthcare Bio-Sciences AB, Uppsala, Sweden). The proteins wer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Gunma University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 29374BDBM29374(proline scaffold, 23)
Affinity DataIC50: 4.00E+5nM Kd:  1.40E+5nMpH: 7.4 T: 2°CAssay Description:SPR experiments where performed with a Biacore A100 using Series S sensor chip CM5 (GE Healthcare Bio-Sciences AB, Uppsala, Sweden). The proteins wer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2009
Entry Details Article
PubMed
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