Compile Data Set for Download or QSAR
Report error Found 203 of ec50 for UniProtKB: Q07817
TargetBcl-2-like protein 1(Human)
Abbott Laboratories

LigandPNGBDBM21449(N-[(4-{[(2R)-4-(dimethylamino)-1-(phenylsulfanyl)b...)
Affinity DataKi: <0.5nM IC50: 60nM EC50:  130nMAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Abbott Laboratories

LigandPNGBDBM21450(N-[(4-{[(2R)-4-(dimethylamino)-1-(phenylsulfanyl)b...)
Affinity DataKi: <0.5nM IC50: 60nM EC50:  40nMAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Abbott Laboratories

LigandPNGBDBM21405(N-[(4-{[(2R)-4-(dimethylamino)-1-(phenylsulfanyl)b...)
Affinity DataKi: <0.5nM ΔG°: <-12.7kcal/mole EC50:  380nMpH: 7.4 T: 2°CAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Abbott Laboratories

LigandPNGBDBM21414(4-{4-[(2-chlorophenyl)methyl]-4-methoxypiperidin-1...)
Affinity DataKi: <0.5nM ΔG°: <-12.7kcal/mole IC50: 62nM EC50:  230nMpH: 7.4 T: 2°CAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Abbott Laboratories

LigandPNGBDBM21415(4-{4-[(3-chlorophenyl)methyl]-4-methoxypiperidin-1...)
Affinity DataKi: <0.5nM ΔG°: <-12.7kcal/mole IC50: 170nM EC50:  250nMpH: 7.4 T: 2°CAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Abbott Laboratories

LigandPNGBDBM21418(N-[(4-{[(2R)-4-(dimethylamino)-1-(phenylsulfanyl)b...)
Affinity DataKi: <0.5nM ΔG°: <-12.7kcal/mole IC50: 71nM EC50:  150nMpH: 7.4 T: 2°CAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Abbott Laboratories

LigandPNGBDBM21420(4-{4-[(2-bromophenyl)methyl]-4-methoxypiperidin-1-...)
Affinity DataKi: <0.5nM ΔG°: <-12.7kcal/mole IC50: 60nM EC50:  100nMpH: 7.4 T: 2°CAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Abbott Laboratories

LigandPNGBDBM21421(N-[(4-{[(2R)-4-(dimethylamino)-1-(phenylsulfanyl)b...)
Affinity DataKi: <0.5nM ΔG°: <-12.7kcal/mole IC50: 60nM EC50:  35nMpH: 7.4 T: 2°CAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Abbott Laboratories

LigandPNGBDBM21423(N-[(4-{[(2R)-4-(dimethylamino)-1-(phenylsulfanyl)b...)
Affinity DataKi: <0.5nM ΔG°: <-12.7kcal/mole IC50: 750nM EC50:  250nMpH: 7.4 T: 2°CAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Abbott Laboratories

LigandPNGBDBM21424(4-{4-[(2-chlorophenyl)methylidene]piperidin-1-yl}-...)
Affinity DataKi: <0.5nM ΔG°: <-12.7kcal/mole IC50: 700nM EC50:  350nMpH: 7.4 T: 2°CAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Abbott Laboratories

LigandPNGBDBM21425(4-{4-[(4-chlorophenyl)methylidene]piperidin-1-yl}-...)
Affinity DataKi: <0.5nM ΔG°: <-12.7kcal/mole IC50: 510nM EC50:  620nMpH: 7.4 T: 2°CAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Abbott Laboratories

LigandPNGBDBM21426(N-[(4-{[(2R)-4-(dimethylamino)-1-(phenylsulfanyl)b...)
Affinity DataKi: <0.5nM ΔG°: <-12.7kcal/mole IC50: 300nM EC50:  150nMpH: 7.4 T: 2°CAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Abbott Laboratories

LigandPNGBDBM21429(4-{4-[(2-cyanophenyl)methylidene]piperidin-1-yl}-N...)
Affinity DataKi: <0.5nM ΔG°: <-12.7kcal/mole IC50: 520nM EC50:  1.10E+3nMpH: 7.4 T: 2°CAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Abbott Laboratories

LigandPNGBDBM21432(N-[(4-{[(2R)-4-(dimethylamino)-1-(phenylsulfanyl)b...)
Affinity DataKi: <0.5nM IC50: 83nM EC50:  160nMAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Abbott Laboratories

LigandPNGBDBM21434(N-[(4-{[(2R)-4-(dimethylamino)-1-(phenylsulfanyl)b...)
Affinity DataKi: <0.5nM IC50: 85nM EC50:  390nMAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Abbott Laboratories

LigandPNGBDBM21435(N-[(4-{[(2R)-4-(dimethylamino)-1-(phenylsulfanyl)b...)
Affinity DataKi: <0.5nM IC50: 80nM EC50:  390nMAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Abbott Laboratories

LigandPNGBDBM21436(N-[(4-{[(2R)-4-(dimethylamino)-1-(phenylsulfanyl)b...)
Affinity DataKi: <0.5nM IC50: 60nM EC50:  95nMAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Abbott Laboratories

LigandPNGBDBM21439(N-[(4-{[(2R)-4-(dimethylamino)-1-(phenylsulfanyl)b...)
Affinity DataKi: <0.5nM IC50: 60nM EC50:  430nMAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Abbott Laboratories

LigandPNGBDBM21440(4-{4-[(2-cyclohexylphenyl)methyl]piperazin-1-yl}-N...)
Affinity DataKi: <0.5nM IC50: 61nM EC50:  340nMAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Abbott Laboratories

LigandPNGBDBM21441(N-[(4-{[(2R)-4-(dimethylamino)-1-(phenylsulfanyl)b...)
Affinity DataKi: <0.5nM IC50: 60nM EC50:  18nMAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Abbott Laboratories

LigandPNGBDBM21442(N-[(4-{[(2R)-4-(dimethylamino)-1-(phenylsulfanyl)b...)
Affinity DataKi: <0.5nM IC50: 81nM EC50:  800nMAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Abbott Laboratories

LigandPNGBDBM21443(N-[(4-{[(2R)-4-(dimethylamino)-1-(phenylsulfanyl)b...)
Affinity DataKi: <0.5nM IC50: 178nM EC50:  380nMAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Abbott Laboratories

LigandPNGBDBM21444(N-[(4-{[(2R)-4-(dimethylamino)-1-(phenylsulfanyl)b...)
Affinity DataKi: <0.5nM IC50: 60nM EC50:  30nMAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Abbott Laboratories

LigandPNGBDBM21445(4-(4-{[2-(2-chlorophenyl)phenyl]methyl}piperazin-1...)
Affinity DataKi: <0.5nM IC50: 60nM EC50:  56nMAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Abbott Laboratories

LigandPNGBDBM21446(4-(4-{[2-(3-chlorophenyl)phenyl]methyl}piperazin-1...)
Affinity DataKi: <0.5nM IC50: 140nM EC50:  180nMAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Abbott Laboratories

LigandPNGBDBM21447(4-(4-{[2-(4-chlorophenyl)phenyl]methyl}piperazin-1...)
Affinity DataKi: <0.5nM IC50: 60nM EC50:  30nMAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Abbott Laboratories

LigandPNGBDBM21438(4-(4-{[2-(cyclohexylamino)phenyl]methyl}piperazin-...)
Affinity DataKi:  0.600nM IC50: 370nM EC50:  660nMAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Abbott Laboratories

LigandPNGBDBM21428(N-[(4-{[(2R)-4-(dimethylamino)-1-(phenylsulfanyl)b...)
Affinity DataKi:  0.600nM ΔG°:  -12.6kcal/mole IC50: 760nM EC50:  300nMpH: 7.4 T: 2°CAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Abbott Laboratories

LigandPNGBDBM21400(N-[(4-{[(2R)-4-(dimethylamino)-1-(phenylsulfanyl)b...)
Affinity DataKi:  0.800nM ΔG°:  -12.4kcal/mole EC50:  470nMpH: 7.4 T: 2°CAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Abbott Laboratories

LigandPNGBDBM21413(4-[4-(cyclohexylmethyl)-4-methoxypiperidin-1-yl]-N...)
Affinity DataKi:  0.800nM ΔG°:  -12.4kcal/mole IC50: 300nM EC50:  320nMpH: 7.4 T: 2°CAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Abbott Laboratories

LigandPNGBDBM21416(4-{4-[(4-chlorophenyl)methyl]-4-methoxypiperidin-1...)
Affinity DataKi:  0.900nM ΔG°:  -12.3kcal/mole IC50: 200nM EC50:  400nMpH: 7.4 T: 2°CAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Abbott Laboratories

LigandPNGBDBM21417(N-[(4-{[(2R)-4-(dimethylamino)-1-(phenylsulfanyl)b...)
Affinity DataKi:  0.900nM ΔG°:  -12.3kcal/mole IC50: 79nM EC50:  180nMpH: 7.4 T: 2°CAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Abbott Laboratories

LigandPNGBDBM21437(N-[(4-{[(2R)-4-(dimethylamino)-1-(phenylsulfanyl)b...)
Affinity DataKi:  0.900nM IC50: 170nM EC50:  5.50E+3nMAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Abbott Laboratories

LigandPNGBDBM21422(N-[(4-{[(2R)-4-(dimethylamino)-1-(phenylsulfanyl)b...)
Affinity DataKi:  0.900nM ΔG°:  -12.3kcal/mole IC50: 160nM EC50:  600nMpH: 7.4 T: 2°CAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Abbott Laboratories

LigandPNGBDBM21448(N-[(4-{[(2R)-4-(dimethylamino)-1-(phenylsulfanyl)b...)
Affinity DataKi:  1nM IC50: 100nM EC50:  22nMAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Abbott Laboratories

LigandPNGBDBM21407(4-(4-benzoylpiperazin-1-yl)-N-[(4-{[(2R)-4-(dimeth...)
Affinity DataKi: <1nM ΔG°: <-12.3kcal/mole EC50:  1.46E+4nMpH: 7.4 T: 2°CAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Abbott Laboratories

LigandPNGBDBM21419(N-[(4-{[(2R)-4-(dimethylamino)-1-(phenylsulfanyl)b...)
Affinity DataKi:  1.10nM ΔG°:  -12.2kcal/mole IC50: 75nM EC50:  150nMpH: 7.4 T: 2°CAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Abbott Laboratories

LigandPNGBDBM21412(4-(4-butyl-4-methoxypiperidin-1-yl)-N-[(4-{[(2R)-4...)
Affinity DataKi:  1.30nM ΔG°:  -12.1kcal/mole IC50: 312nM EC50:  8.00E+3nMpH: 7.4 T: 2°CAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Abbott Laboratories

LigandPNGBDBM21431(N-[(4-{[(2R)-4-(dimethylamino)-1-(phenylsulfanyl)b...)
Affinity DataKi:  1.30nM IC50: 2.80E+3nM EC50:  1.90E+3nMAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Abbott Laboratories

LigandPNGBDBM21427(N-[(4-{[(2R)-4-(dimethylamino)-1-(phenylsulfanyl)b...)
Affinity DataKi:  1.40nM ΔG°:  -12.1kcal/mole IC50: 1.30E+3nM EC50:  2.60E+3nMpH: 7.4 T: 2°CAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Abbott Laboratories

LigandPNGBDBM21403(4-{3-benzyl-1-oxa-2,8-diazaspiro[4.5]dec-2-en-8-yl...)
Affinity DataKi:  1.70nM ΔG°:  -12.0kcal/mole EC50:  2.34E+3nMpH: 7.4 T: 2°CAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Abbott Laboratories

LigandPNGBDBM21401(4-(4-benzyl-4-methoxypiperidin-1-yl)-N-[(4-{[(2R)-...)
Affinity DataKi:  1.80nM ΔG°:  -11.9kcal/mole IC50: 150nM EC50:  680nMpH: 7.4 T: 2°CAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Abbott Laboratories

LigandPNGBDBM21409(4-(4-{[(4-{[(2R)-4-(dimethylamino)-1-(phenylsulfan...)
Affinity DataKi:  2.5nM ΔG°:  -11.7kcal/mole EC50: >5.00E+4nMpH: 7.4 T: 2°CAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Abbott Laboratories

LigandPNGBDBM21406(4-(4-benzylpiperazin-1-yl)-N-[(4-{[(2R)-4-(dimethy...)
Affinity DataKi:  2.60nM ΔG°:  -11.7kcal/mole EC50:  1.10E+3nMpH: 7.4 T: 2°CAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Abbott Laboratories

LigandPNGBDBM21433(N-[(4-{[(2R)-4-(dimethylamino)-1-(phenylsulfanyl)b...)
Affinity DataKi:  3nM IC50: 140nM EC50:  410nMAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Abbott Laboratories

LigandPNGBDBM21430(N-[(4-{[(2R)-4-(dimethylamino)-1-(phenylsulfanyl)b...)
Affinity DataKi:  3.60nM IC50: 700nM EC50:  550nMAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Abbott Laboratories

LigandPNGBDBM21404(4-{4-benzyl-2-methyl-3-oxo-1-oxa-4,8-diazaspiro[4....)
Affinity DataKi:  3.70nM ΔG°:  -11.5kcal/mole EC50: >2.00E+4nMpH: 7.4 T: 2°CAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Abbott Laboratories

LigandPNGBDBM21408(N-[(4-{[(2R)-4-(dimethylamino)-1-(phenylsulfanyl)b...)
Affinity DataKi:  4nM ΔG°:  -11.4kcal/mole EC50: >2.00E+4nMpH: 7.4 T: 2°CAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Abbott Laboratories

LigandPNGBDBM21402(N-[(4-{[(2R)-4-(dimethylamino)-1-(phenylsulfanyl)b...)
Affinity DataKi:  4.40nM ΔG°:  -11.4kcal/mole EC50: >5.00E+4nMpH: 7.4 T: 2°CAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Abbott Laboratories

LigandPNGBDBM21411(N-[(4-{[(2R)-4-(dimethylamino)-1-(phenylsulfanyl)b...)
Affinity DataKi:  4.60nM ΔG°:  -11.4kcal/mole IC50: 440nM EC50:  750nMpH: 7.4 T: 2°CAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
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