Compile Data Set for Download or QSAR
Report error Found 1512 of ic50 for UniProtKB: Q07817
TargetBcl-2-like protein 1(Human)
Abbott Laboratories

LigandPNGBDBM21449(N-[(4-{[(2R)-4-(dimethylamino)-1-(phenylsulfanyl)b...)
Affinity DataKi: <0.5nM IC50: 60nM EC50:  130nMAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Abbott Laboratories

LigandPNGBDBM21450(N-[(4-{[(2R)-4-(dimethylamino)-1-(phenylsulfanyl)b...)
Affinity DataKi: <0.5nM IC50: 60nM EC50:  40nMAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Abbott Laboratories

LigandPNGBDBM156403(US9018381, 26 | US9248140, 26)
Affinity DataIC50: 0.5nMAssay Description:Bcl-xL and Bcl-2 FP binding affinity of compound(s) of Formulae (I), (I-a), (I-b), (I-c), (I-d) and/or (I-e) may be determined using a variety of kno...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2015
Entry Details
US Patent

TargetBcl-2-like protein 1(Human)
Abbott Laboratories

LigandPNGBDBM21414(4-{4-[(2-chlorophenyl)methyl]-4-methoxypiperidin-1...)
Affinity DataKi: <0.5nM ΔG°: <-12.7kcal/mole IC50: 62nM EC50:  230nMpH: 7.4 T: 2°CAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Abbott Laboratories

LigandPNGBDBM21415(4-{4-[(3-chlorophenyl)methyl]-4-methoxypiperidin-1...)
Affinity DataKi: <0.5nM ΔG°: <-12.7kcal/mole IC50: 170nM EC50:  250nMpH: 7.4 T: 2°CAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Abbott Laboratories

LigandPNGBDBM21418(N-[(4-{[(2R)-4-(dimethylamino)-1-(phenylsulfanyl)b...)
Affinity DataKi: <0.5nM ΔG°: <-12.7kcal/mole IC50: 71nM EC50:  150nMpH: 7.4 T: 2°CAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Abbott Laboratories

LigandPNGBDBM21420(4-{4-[(2-bromophenyl)methyl]-4-methoxypiperidin-1-...)
Affinity DataKi: <0.5nM ΔG°: <-12.7kcal/mole IC50: 60nM EC50:  100nMpH: 7.4 T: 2°CAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Abbott Laboratories

LigandPNGBDBM21421(N-[(4-{[(2R)-4-(dimethylamino)-1-(phenylsulfanyl)b...)
Affinity DataKi: <0.5nM ΔG°: <-12.7kcal/mole IC50: 60nM EC50:  35nMpH: 7.4 T: 2°CAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Abbott Laboratories

LigandPNGBDBM21423(N-[(4-{[(2R)-4-(dimethylamino)-1-(phenylsulfanyl)b...)
Affinity DataKi: <0.5nM ΔG°: <-12.7kcal/mole IC50: 750nM EC50:  250nMpH: 7.4 T: 2°CAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Abbott Laboratories

LigandPNGBDBM21424(4-{4-[(2-chlorophenyl)methylidene]piperidin-1-yl}-...)
Affinity DataKi: <0.5nM ΔG°: <-12.7kcal/mole IC50: 700nM EC50:  350nMpH: 7.4 T: 2°CAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Abbott Laboratories

LigandPNGBDBM21425(4-{4-[(4-chlorophenyl)methylidene]piperidin-1-yl}-...)
Affinity DataKi: <0.5nM ΔG°: <-12.7kcal/mole IC50: 510nM EC50:  620nMpH: 7.4 T: 2°CAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Abbott Laboratories

LigandPNGBDBM21426(N-[(4-{[(2R)-4-(dimethylamino)-1-(phenylsulfanyl)b...)
Affinity DataKi: <0.5nM ΔG°: <-12.7kcal/mole IC50: 300nM EC50:  150nMpH: 7.4 T: 2°CAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Abbott Laboratories

LigandPNGBDBM21447(4-(4-{[2-(4-chlorophenyl)phenyl]methyl}piperazin-1...)
Affinity DataIC50: 0.5nMAssay Description:Binding affinity to human GST-tagged Bcl-Xl by luminescence proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Abbott Laboratories

LigandPNGBDBM21429(4-{4-[(2-cyanophenyl)methylidene]piperidin-1-yl}-N...)
Affinity DataKi: <0.5nM ΔG°: <-12.7kcal/mole IC50: 520nM EC50:  1.10E+3nMpH: 7.4 T: 2°CAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Abbott Laboratories

LigandPNGBDBM21432(N-[(4-{[(2R)-4-(dimethylamino)-1-(phenylsulfanyl)b...)
Affinity DataKi: <0.5nM IC50: 83nM EC50:  160nMAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Abbott Laboratories

LigandPNGBDBM21434(N-[(4-{[(2R)-4-(dimethylamino)-1-(phenylsulfanyl)b...)
Affinity DataKi: <0.5nM IC50: 85nM EC50:  390nMAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Abbott Laboratories

LigandPNGBDBM21435(N-[(4-{[(2R)-4-(dimethylamino)-1-(phenylsulfanyl)b...)
Affinity DataKi: <0.5nM IC50: 80nM EC50:  390nMAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Abbott Laboratories

LigandPNGBDBM21436(N-[(4-{[(2R)-4-(dimethylamino)-1-(phenylsulfanyl)b...)
Affinity DataKi: <0.5nM IC50: 60nM EC50:  95nMAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Abbott Laboratories

LigandPNGBDBM21439(N-[(4-{[(2R)-4-(dimethylamino)-1-(phenylsulfanyl)b...)
Affinity DataKi: <0.5nM IC50: 60nM EC50:  430nMAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Abbott Laboratories

LigandPNGBDBM21440(4-{4-[(2-cyclohexylphenyl)methyl]piperazin-1-yl}-N...)
Affinity DataKi: <0.5nM IC50: 61nM EC50:  340nMAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Abbott Laboratories

LigandPNGBDBM156398(US9018381, 21)
Affinity DataIC50: 0.5nMAssay Description:Bcl-xL and Bcl-2 FP binding affinity of compound(s) of Formulae (I), (I-a), (I-b), (I-c), (I-d) and/or (I-e) may be determined using a variety of kno...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2015
Entry Details
US Patent

TargetBcl-2-like protein 1(Human)
Abbott Laboratories

LigandPNGBDBM21441(N-[(4-{[(2R)-4-(dimethylamino)-1-(phenylsulfanyl)b...)
Affinity DataKi: <0.5nM IC50: 60nM EC50:  18nMAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Abbott Laboratories

LigandPNGBDBM21442(N-[(4-{[(2R)-4-(dimethylamino)-1-(phenylsulfanyl)b...)
Affinity DataKi: <0.5nM IC50: 81nM EC50:  800nMAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Abbott Laboratories

LigandPNGBDBM21443(N-[(4-{[(2R)-4-(dimethylamino)-1-(phenylsulfanyl)b...)
Affinity DataKi: <0.5nM IC50: 178nM EC50:  380nMAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Abbott Laboratories

LigandPNGBDBM21444(N-[(4-{[(2R)-4-(dimethylamino)-1-(phenylsulfanyl)b...)
Affinity DataKi: <0.5nM IC50: 60nM EC50:  30nMAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Abbott Laboratories

LigandPNGBDBM21445(4-(4-{[2-(2-chlorophenyl)phenyl]methyl}piperazin-1...)
Affinity DataKi: <0.5nM IC50: 60nM EC50:  56nMAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Abbott Laboratories

LigandPNGBDBM21446(4-(4-{[2-(3-chlorophenyl)phenyl]methyl}piperazin-1...)
Affinity DataKi: <0.5nM IC50: 140nM EC50:  180nMAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Abbott Laboratories

LigandPNGBDBM21447(4-(4-{[2-(4-chlorophenyl)phenyl]methyl}piperazin-1...)
Affinity DataKi: <0.5nM IC50: 60nM EC50:  30nMAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Abbott Laboratories

LigandPNGBDBM21438(4-(4-{[2-(cyclohexylamino)phenyl]methyl}piperazin-...)
Affinity DataKi:  0.600nM IC50: 370nM EC50:  660nMAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Abbott Laboratories

LigandPNGBDBM21428(N-[(4-{[(2R)-4-(dimethylamino)-1-(phenylsulfanyl)b...)
Affinity DataKi:  0.600nM ΔG°:  -12.6kcal/mole IC50: 760nM EC50:  300nMpH: 7.4 T: 2°CAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Abbott Laboratories

LigandPNGBDBM21413(4-[4-(cyclohexylmethyl)-4-methoxypiperidin-1-yl]-N...)
Affinity DataKi:  0.800nM ΔG°:  -12.4kcal/mole IC50: 300nM EC50:  320nMpH: 7.4 T: 2°CAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Abbott Laboratories

LigandPNGBDBM156380(US9018381, 4 | US9248140, 4)
Affinity DataIC50: 0.800nMAssay Description:Bcl-xL and Bcl-2 FP binding affinity of compound(s) of Formulae (I), (I-a), (I-b), (I-c), (I-d) and/or (I-e) may be determined using a variety of kno...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2015
Entry Details
US Patent

TargetBcl-2-like protein 1(Human)
Abbott Laboratories

LigandPNGBDBM21416(4-{4-[(4-chlorophenyl)methyl]-4-methoxypiperidin-1...)
Affinity DataKi:  0.900nM ΔG°:  -12.3kcal/mole IC50: 200nM EC50:  400nMpH: 7.4 T: 2°CAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Abbott Laboratories

LigandPNGBDBM21417(N-[(4-{[(2R)-4-(dimethylamino)-1-(phenylsulfanyl)b...)
Affinity DataKi:  0.900nM ΔG°:  -12.3kcal/mole IC50: 79nM EC50:  180nMpH: 7.4 T: 2°CAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Abbott Laboratories

LigandPNGBDBM21437(N-[(4-{[(2R)-4-(dimethylamino)-1-(phenylsulfanyl)b...)
Affinity DataKi:  0.900nM IC50: 170nM EC50:  5.50E+3nMAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Abbott Laboratories

LigandPNGBDBM21422(N-[(4-{[(2R)-4-(dimethylamino)-1-(phenylsulfanyl)b...)
Affinity DataKi:  0.900nM ΔG°:  -12.3kcal/mole IC50: 160nM EC50:  600nMpH: 7.4 T: 2°CAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Abbott Laboratories

LigandPNGBDBM21448(N-[(4-{[(2R)-4-(dimethylamino)-1-(phenylsulfanyl)b...)
Affinity DataKi:  1nM IC50: 100nM EC50:  22nMAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2008
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Abbott Laboratories

LigandPNGBDBM156407(US9018381, 30 | US9248140, 30)
Affinity DataIC50: 1nMAssay Description:Bcl-xL and Bcl-2 FP binding affinity of compound(s) of Formulae (I), (I-a), (I-b), (I-c), (I-d) and/or (I-e) may be determined using a variety of kno...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2015
Entry Details
US Patent

TargetBcl-2-like protein 1(Human)
Abbott Laboratories

LigandPNGBDBM156382(US9018381, 5 | US9248140, 5)
Affinity DataIC50: 1nMAssay Description:Bcl-xL and Bcl-2 FP binding affinity of compound(s) of Formulae (I), (I-a), (I-b), (I-c), (I-d) and/or (I-e) may be determined using a variety of kno...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2015
Entry Details
US Patent

TargetBcl-2-like protein 1(Human)
Abbott Laboratories

LigandPNGBDBM156384(US9018381, 7 | US9248140, 7)
Affinity DataIC50: 1nMAssay Description:Bcl-xL and Bcl-2 FP binding affinity of compound(s) of Formulae (I), (I-a), (I-b), (I-c), (I-d) and/or (I-e) may be determined using a variety of kno...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2015
Entry Details
US Patent

TargetBcl-2-like protein 1(Human)
Abbott Laboratories

LigandPNGBDBM156385(US9018381, 8 | US9248140, 8)
Affinity DataIC50: 1nMAssay Description:Bcl-xL and Bcl-2 FP binding affinity of compound(s) of Formulae (I), (I-a), (I-b), (I-c), (I-d) and/or (I-e) may be determined using a variety of kno...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2015
Entry Details
US Patent

TargetBcl-2-like protein 1(Human)
Abbott Laboratories

LigandPNGBDBM156376(US9018381, 1 | US9248140, 1)
Affinity DataIC50: 1nMAssay Description:Bcl-xL and Bcl-2 FP binding affinity of compound(s) of Formulae (I), (I-a), (I-b), (I-c), (I-d) and/or (I-e) may be determined using a variety of kno...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2015
Entry Details
US Patent

TargetBcl-2-like protein 1(Human)
Abbott Laboratories

LigandPNGBDBM156377(US9018381, 2 | US9248140, 2)
Affinity DataIC50: 1nMAssay Description:Bcl-xL and Bcl-2 FP binding affinity of compound(s) of Formulae (I), (I-a), (I-b), (I-c), (I-d) and/or (I-e) may be determined using a variety of kno...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2015
Entry Details
US Patent

TargetBcl-2-like protein 1(Human)
Abbott Laboratories

LigandPNGBDBM156378(US9018381, 3 | US9248140, 3)
Affinity DataIC50: 1nMAssay Description:Bcl-xL and Bcl-2 FP binding affinity of compound(s) of Formulae (I), (I-a), (I-b), (I-c), (I-d) and/or (I-e) may be determined using a variety of kno...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2015
Entry Details
US Patent

TargetBcl-2-like protein 1(Human)
Abbott Laboratories

LigandPNGBDBM21447(4-(4-{[2-(4-chlorophenyl)phenyl]methyl}piperazin-1...)
Affinity DataIC50: 1nMAssay Description:Inhibition of Bcl-XLMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Abbott Laboratories

LigandPNGBDBM50020938(CHEMBL3287301)
Affinity DataIC50: 1nMAssay Description:Displacement of 26-mer BIMBH3 peptide from GST-tagged Bcl-Xl (unknown origin) by AlphaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2015
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Abbott Laboratories

LigandPNGBDBM156392(US9018381, 15 | US9248140, 15)
Affinity DataIC50: 1nMAssay Description:Bcl-xL and Bcl-2 FP binding affinity of compound(s) of Formulae (I), (I-a), (I-b), (I-c), (I-d) and/or (I-e) may be determined using a variety of kno...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2015
Entry Details
US Patent

TargetBcl-2-like protein 1(Human)
Abbott Laboratories

LigandPNGBDBM156393(US9018381, 16 | US9248140, 16)
Affinity DataIC50: 1nMAssay Description:Bcl-xL and Bcl-2 FP binding affinity of compound(s) of Formulae (I), (I-a), (I-b), (I-c), (I-d) and/or (I-e) may be determined using a variety of kno...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2015
Entry Details
US Patent

TargetBcl-2-like protein 1(Human)
Abbott Laboratories

LigandPNGBDBM156386(US9018381, 9 | US9248140, 9)
Affinity DataIC50: 1nMAssay Description:Bcl-xL and Bcl-2 FP binding affinity of compound(s) of Formulae (I), (I-a), (I-b), (I-c), (I-d) and/or (I-e) may be determined using a variety of kno...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2015
Entry Details
US Patent

TargetBcl-2-like protein 1(Human)
Abbott Laboratories

LigandPNGBDBM156387(US9018381, 10 | US9248140, 10)
Affinity DataIC50: 1nMAssay Description:Bcl-xL and Bcl-2 FP binding affinity of compound(s) of Formulae (I), (I-a), (I-b), (I-c), (I-d) and/or (I-e) may be determined using a variety of kno...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2015
Entry Details
US Patent

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