Compile Data Set for Download or QSAR
Report error Found 478 of ki for UniProtKB: Q16539
TargetMitogen-activated protein kinase 14(Human)
Bristol-Myers Squibb

LigandChemical structure of BindingDB Monomer ID 16318BDBM16318(3-({5-cyano-6-[(2,2-dimethylpropyl)(methyl)amino]-...)
Affinity DataKi:  0.0470nM ΔG°:  -13.9kcal/molepH: 7.4 T: 2°CAssay Description:The kinase activity was determined by quantitation of the amount of radioactive phosphate transferred to myelin basic protein (MBP) with or without i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bristol-Myers Squibb

LigandChemical structure of BindingDB Monomer ID 16319BDBM16319(3-({2-amino-5-cyano-6-[(2,2-dimethylpropyl)(methyl...)
Affinity DataKi:  0.0500nM ΔG°:  -13.9kcal/molepH: 7.4 T: 2°CAssay Description:The kinase activity was determined by quantitation of the amount of radioactive phosphate transferred to myelin basic protein (MBP) with or without i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bristol-Myers Squibb

LigandChemical structure of BindingDB Monomer ID 16317BDBM16317(3-({5-cyano-6-[(2,2-dimethylpropyl)(methyl)amino]-...)
Affinity DataKi:  0.0570nM ΔG°:  -13.8kcal/molepH: 7.4 T: 2°CAssay Description:The kinase activity was determined by quantitation of the amount of radioactive phosphate transferred to myelin basic protein (MBP) with or without i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bristol-Myers Squibb

LigandChemical structure of BindingDB Monomer ID 16329BDBM16329(3-{[2-amino-5-cyano-6-(propan-2-ylamino)pyrimidin-...)
Affinity DataKi:  0.0570nM ΔG°:  -13.8kcal/molepH: 7.4 T: 2°CAssay Description:The kinase activity was determined by quantitation of the amount of radioactive phosphate transferred to myelin basic protein (MBP) with or without i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bristol-Myers Squibb

LigandChemical structure of BindingDB Monomer ID 13533BDBM13533(1-[5-tert-butyl-2-(p-tolyl)pyrazol-3-yl]-3-[4-(2-m...)
Affinity DataKi:  0.100nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bristol-Myers Squibb

LigandChemical structure of BindingDB Monomer ID 16320BDBM16320(3-({5-cyano-6-[(2,2-dimethylpropyl)(methyl)amino]p...)
Affinity DataKi:  0.150nM ΔG°:  -13.3kcal/molepH: 7.4 T: 2°CAssay Description:The kinase activity was determined by quantitation of the amount of radioactive phosphate transferred to myelin basic protein (MBP) with or without i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bristol-Myers Squibb

LigandChemical structure of BindingDB Monomer ID 16330BDBM16330(3-{[2-amino-5-cyano-6-(cyclopentylamino)pyrimidin-...)
Affinity DataKi:  0.160nM ΔG°:  -13.2kcal/molepH: 7.4 T: 2°CAssay Description:The kinase activity was determined by quantitation of the amount of radioactive phosphate transferred to myelin basic protein (MBP) with or without i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bristol-Myers Squibb

LigandChemical structure of BindingDB Monomer ID 50253148BDBM50253148(N-(S)-sec-Butyl-6-(6-methyl-3-(methylamino)benzo[d...)
Affinity DataKi:  0.200nMAssay Description:Inhibition of human recombinant GST-tagged p38alphaMAPK-induced ATF2 phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bristol-Myers Squibb

LigandChemical structure of BindingDB Monomer ID 50376226BDBM50376226(CHEMBL259922)
Affinity DataKi:  0.200nMAssay Description:Inhibition of human recombinant p38alpha-mediated myelin basic protein phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bristol-Myers Squibb

LigandChemical structure of BindingDB Monomer ID 50253105BDBM50253105(6-Chloro-N-cyclopropyl-7-(1-((S)-3-methylmorpholin...)
Affinity DataKi:  0.200nMAssay Description:Inhibition of human recombinant GST-tagged p38alphaMAPK-induced ATF2 phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bristol-Myers Squibb

LigandChemical structure of BindingDB Monomer ID 50376226BDBM50376226(CHEMBL259922)
Affinity DataKi:  0.200nMAssay Description:Inhibition of human recombinant p38alpha-mediated myelin basic protein phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bristol-Myers Squibb

LigandChemical structure of BindingDB Monomer ID 50253150BDBM50253150(N,6-Dimethyl-7-(1-((R)-3-methylmorpholino)phthalaz...)
Affinity DataKi:  0.300nMAssay Description:Inhibition of human recombinant GST-tagged p38alphaMAPK-induced ATF2 phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bristol-Myers Squibb

LigandChemical structure of BindingDB Monomer ID 50253102BDBM50253102(6-Methyl-7-(1-((S)-3-methylmorpholino)phthalazin-6...)
Affinity DataKi:  0.300nMAssay Description:Inhibition of human recombinant GST-tagged p38alphaMAPK-induced ATF2 phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bristol-Myers Squibb

LigandChemical structure of BindingDB Monomer ID 50252776BDBM50252776(N-Ethyl-6-methyl-7-(1-((S)-3-methylmorpholino)phth...)
Affinity DataKi:  0.300nMAssay Description:Inhibition of human recombinant GST-tagged p38alphaMAPK-induced ATF2 phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bristol-Myers Squibb

LigandChemical structure of BindingDB Monomer ID 50252735BDBM50252735(N-Cyclopropyl-6-methyl-7-(1-o-tolylphthalazin-6-yl...)
Affinity DataKi:  0.400nMAssay Description:Inhibition of human recombinant GST-tagged p38alphaMAPK-induced ATF2 phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bristol-Myers Squibb

LigandChemical structure of BindingDB Monomer ID 50253154BDBM50253154(N-Cyclopropyl-4-methyl-3-(1-(2-methylphenyl)-6-pht...)
Affinity DataKi:  0.400nMAssay Description:Inhibition of P38alpha MAPK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bristol-Myers Squibb

LigandChemical structure of BindingDB Monomer ID 50253103BDBM50253103(7-(1-Isopropoxyphthalazin-6-yl)-N,6-dimethylbenzo[...)
Affinity DataKi:  0.400nMAssay Description:Inhibition of human recombinant GST-tagged p38alphaMAPK-induced ATF2 phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bristol-Myers Squibb

LigandChemical structure of BindingDB Monomer ID 50253149BDBM50253149(6-Chloro-N-isopropyl-7-(1-((S)-3-methylmorpholino)...)
Affinity DataKi:  0.400nMAssay Description:Inhibition of human recombinant GST-tagged p38alphaMAPK-induced ATF2 phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bristol-Myers Squibb

LigandChemical structure of BindingDB Monomer ID 50252777BDBM50252777(N,6-Dimethyl-7-(1-((S)-3-methylmorpholino)phthalaz...)
Affinity DataKi:  0.400nMAssay Description:Inhibition of human recombinant GST-tagged p38alphaMAPK-induced ATF2 phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bristol-Myers Squibb

LigandChemical structure of BindingDB Monomer ID 16325BDBM16325(3-({5-cyano-6-[(1-methylethyl)amino]pyrimidin-4-yl...)
Affinity DataKi:  0.410nM ΔG°:  -12.7kcal/molepH: 7.4 T: 2°CAssay Description:The kinase activity was determined by quantitation of the amount of radioactive phosphate transferred to myelin basic protein (MBP) with or without i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bristol-Myers Squibb

LigandChemical structure of BindingDB Monomer ID 50376456BDBM50376456(CHEMBL262592)
Affinity DataKi:  0.420nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bristol-Myers Squibb

LigandChemical structure of BindingDB Monomer ID 16324BDBM16324(3-{[5-cyano-6-(cyclopentylamino)pyrimidin-4-yl]ami...)
Affinity DataKi:  0.420nM ΔG°:  -12.7kcal/molepH: 7.4 T: 2°CAssay Description:The kinase activity was determined by quantitation of the amount of radioactive phosphate transferred to myelin basic protein (MBP) with or without i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bristol-Myers Squibb

LigandChemical structure of BindingDB Monomer ID 50376433BDBM50376433(CHEMBL258895)
Affinity DataKi:  0.440nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bristol-Myers Squibb

LigandChemical structure of BindingDB Monomer ID 50376434BDBM50376434(CHEMBL408150)
Affinity DataKi:  0.460nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bristol-Myers Squibb

LigandChemical structure of BindingDB Monomer ID 50253147BDBM50253147(N-Isopropyl-6-(6-methyl-3-(methylamino)benzo[d]iso...)
Affinity DataKi:  0.5nMAssay Description:Inhibition of human recombinant GST-tagged p38alphaMAPK-induced ATF2 phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bristol-Myers Squibb

LigandChemical structure of BindingDB Monomer ID 50252775BDBM50252775(6-(3-(cyclopropylamino)-6-methylbenzo[d]isoxazol-7...)
Affinity DataKi:  0.5nMAssay Description:Inhibition of human recombinant GST-tagged p38alphaMAPK-induced ATF2 phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bristol-Myers Squibb

LigandChemical structure of BindingDB Monomer ID 50376435BDBM50376435(CHEMBL261845)
Affinity DataKi:  0.540nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bristol-Myers Squibb

LigandChemical structure of BindingDB Monomer ID 50263211BDBM50263211(2-Cyclobutylamino-N-[4'-(cyclopropylmethyl-carbamo...)
Affinity DataKi:  0.600nMAssay Description:Displacement of rhodamine-green labeled (2-(6-amino-3-imino-3H-xanthen-9-yl)-5-{[({4-[4-(4-Cl-3-hydroxyphenyl)-5-(4-pyridinyl)-1H-imidazol-2yl]phenyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bristol-Myers Squibb

LigandChemical structure of BindingDB Monomer ID 50253104BDBM50253104(N-(6-Methyl-7-(1-((S)-3-methylmorpholino)phthalazi...)
Affinity DataKi:  0.600nMAssay Description:Inhibition of human recombinant GST-tagged p38alphaMAPK-induced ATF2 phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bristol-Myers Squibb

LigandChemical structure of BindingDB Monomer ID 50314782BDBM50314782(N-Cyclopropyl-3-(1-(2,4-difluorophenyl)-7-ethyl-6-...)
Affinity DataKi:  0.600nMAssay Description:Inhibition of human recombinant p38alpha-mediated AFT2 phosphorylation after 1 hr by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bristol-Myers Squibb

LigandChemical structure of BindingDB Monomer ID 16323BDBM16323(3-({5-cyano-6-[(1-methylethyl)amino]pyrimidin-4-yl...)
Affinity DataKi:  0.610nM ΔG°:  -12.4kcal/molepH: 7.4 T: 2°CAssay Description:The kinase activity was determined by quantitation of the amount of radioactive phosphate transferred to myelin basic protein (MBP) with or without i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bristol-Myers Squibb

LigandChemical structure of BindingDB Monomer ID 50252736BDBM50252736(N-Cyclopropyl-6-methyl-7-(1-((S)-3-methylmorpholin...)
Affinity DataKi:  0.700nMAssay Description:Inhibition of human recombinant GST-tagged p38alphaMAPK-induced ATF2 phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bristol-Myers Squibb

LigandChemical structure of BindingDB Monomer ID 50264756BDBM50264756(N-(4-methyl-3-(3-(piperidin-4-yl)benzo[d]isoxazol-...)
Affinity DataKi:  0.800nMAssay Description:Displacement of fluorescent ATP competitive ligand from p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bristol-Myers Squibb

LigandChemical structure of BindingDB Monomer ID 50314785BDBM50314785(N-Cyclopropyl-3-(1-(2,6-difluorophenyl)-7-methyl-6...)
Affinity DataKi:  0.800nMAssay Description:Inhibition of human recombinant p38alpha-mediated AFT2 phosphorylation after 1 hr by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bristol-Myers Squibb

LigandChemical structure of BindingDB Monomer ID 50252774BDBM50252774(1-((S)-4-(6-(3-(Cyclopropylamino)-6-methylbenzo[d]...)
Affinity DataKi:  0.800nMAssay Description:Inhibition of human recombinant GST-tagged p38alphaMAPK-induced ATF2 phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bristol-Myers Squibb

LigandChemical structure of BindingDB Monomer ID 50314778BDBM50314778(3-(1-(2-Chlorophenyl)-7-methyl-6-oxo-6,7-dihydro-1...)
Affinity DataKi:  0.900nMAssay Description:Inhibition of human recombinant p38alpha-mediated AFT2 phosphorylation after 1 hr by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bristol-Myers Squibb

LigandChemical structure of BindingDB Monomer ID 16322BDBM16322(3-{[5-cyano-6-(propylamino)pyrimidin-4-yl]amino}-N...)
Affinity DataKi:  0.970nM ΔG°:  -12.2kcal/molepH: 7.4 T: 2°CAssay Description:The kinase activity was determined by quantitation of the amount of radioactive phosphate transferred to myelin basic protein (MBP) with or without i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bristol-Myers Squibb

LigandChemical structure of BindingDB Monomer ID 50376432BDBM50376432(CHEMBL258748)
Affinity DataKi:  0.980nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bristol-Myers Squibb

LigandChemical structure of BindingDB Monomer ID 50314788BDBM50314788(3-(1-(2,6-Difluorophenyl)-7-methyl-6-oxo-6,7-dihyd...)
Affinity DataKi:  1nMAssay Description:Inhibition of human recombinant p38alpha-mediated AFT2 phosphorylation after 1 hr by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bristol-Myers Squibb

LigandChemical structure of BindingDB Monomer ID 50313107BDBM50313107(4-chloro-N-cyclopropyl-3-{[1-(2,6-difluorophenyl)-...)
Affinity DataKi:  1nMAssay Description:Inhibition of P38alpha MAPK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bristol-Myers Squibb

LigandChemical structure of BindingDB Monomer ID 50253101BDBM50253101(7-(1-Isopropylphthalazin-6-yl)-N,6-dimethylbenzo[d...)
Affinity DataKi:  1.10nMAssay Description:Inhibition of human recombinant GST-tagged p38alphaMAPK-induced ATF2 phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bristol-Myers Squibb

LigandChemical structure of BindingDB Monomer ID 50314784BDBM50314784(4-Chloro-N-cyclopropyl-3-(1-(2,6-difluorophenyl)-7...)
Affinity DataKi:  1.10nMAssay Description:Inhibition of human recombinant p38alpha-mediated AFT2 phosphorylation after 1 hr by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bristol-Myers Squibb

LigandChemical structure of BindingDB Monomer ID 50264993BDBM50264993(N-(6-methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)biph...)
Affinity DataKi:  1.10nMAssay Description:Displacement of fluorescent ATP competitive ligand from p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bristol-Myers Squibb

LigandChemical structure of BindingDB Monomer ID 50264755BDBM50264755(4-methyl-N-(3-morpholin-4-ylphenyl)-3-(3-piperidin...)
Affinity DataKi:  1.40nMAssay Description:Displacement of fluorescent ATP competitive ligand from p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bristol-Myers Squibb

LigandChemical structure of BindingDB Monomer ID 50314776BDBM50314776(N-Cyclopropyl-3-(1-(2,6-difluorophenyl)-7-methyl-6...)
Affinity DataKi:  1.40nMAssay Description:Inhibition of human recombinant p38alpha-mediated AFT2 phosphorylation after 1 hr by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bristol-Myers Squibb

LigandChemical structure of BindingDB Monomer ID 50314786BDBM50314786(3-(1-(2,6-Difluorophenyl)-7-methyl-6-oxo-6,7-dihyd...)
Affinity DataKi:  1.5nMAssay Description:Inhibition of human recombinant p38alpha-mediated AFT2 phosphorylation after 1 hr by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bristol-Myers Squibb

LigandChemical structure of BindingDB Monomer ID 16331BDBM16331(3-({2-amino-5-cyano-6-[(1-methylethyl)amino]pyrimi...)
Affinity DataKi:  1.5nM ΔG°:  -11.9kcal/molepH: 7.4 T: 2°CAssay Description:The kinase activity was determined by quantitation of the amount of radioactive phosphate transferred to myelin basic protein (MBP) with or without i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bristol-Myers Squibb

LigandChemical structure of BindingDB Monomer ID 16326BDBM16326(3-{[5-cyano-6-(cyclopentylamino)pyrimidin-4-yl]ami...)
Affinity DataKi:  1.60nM ΔG°:  -11.9kcal/molepH: 7.4 T: 2°CAssay Description:The kinase activity was determined by quantitation of the amount of radioactive phosphate transferred to myelin basic protein (MBP) with or without i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bristol-Myers Squibb

LigandChemical structure of BindingDB Monomer ID 50263261BDBM50263261(5'-(3-Furan-3-yl-benzoylamino)-2'-methyl-biphenyl-...)
Affinity DataKi:  1.60nMAssay Description:Displacement of rhodamine-green labeled (2-(6-amino-3-imino-3H-xanthen-9-yl)-5-{[({4-[4-(4-Cl-3-hydroxyphenyl)-5-(4-pyridinyl)-1H-imidazol-2yl]phenyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Bristol-Myers Squibb

LigandChemical structure of BindingDB Monomer ID 50314787BDBM50314787(3-(1-(2,6-Difluorophenyl)-7-methyl-6-oxo-6,7-dihyd...)
Affinity DataKi:  1.70nMAssay Description:Inhibition of human recombinant p38alpha-mediated AFT2 phosphorylation after 1 hr by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
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