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TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM203875(7-(3-((4-Borono-3-formylphenoxy)methyl)-1,5-dimeth...)
Affinity DataEC50:  75nMAssay Description:Inhibition of MCL-1 in human MOLP8 cells assessed as increase in caspase 3/7 activationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM203876(Mcl-1 inhibitor 12)
Affinity DataEC50:  340nMAssay Description:Inhibition of MCL-1 in human MOLP8 cells assessed as increase in caspase 3/7 activationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM32328(MLS000674601 | cid_16195481 | SMR000314043 | 4-{2-...)
Affinity DataEC50:  360nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2011
Entry Details
PCBioAssay
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM32318(cid_5337459 | 4-[[4-(2-methyl-3-imidazo[1,2-a]pyri...)
Affinity DataEC50:  390nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2011
Entry Details
PCBioAssay
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM203869(7-(3-((4-Borono-3-formylphenoxy)methyl)-1,5-dimeth...)
Affinity DataEC50:  460nMAssay Description:Inhibition of MCL-1 in human MOLP8 cells assessed as increase in caspase 3/7 activationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50376902(CHEMBL408194)
Affinity DataEC50:  500nMAssay Description:Inhibition of GST-tagged recombinant Mcl1 interaction with biotinylated Bim peptide by ELISA based competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM54714(3-chloro-4-[(1,5-dimethyl-3-oxo-2-phenylpyrazolidi...)
Affinity DataEC50:  540nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2011
Entry Details
PCBioAssay
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM32274(cid_1002249 | SMR000115103 | 2,5-dichloro-3-(4-met...)
Affinity DataEC50:  700nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2011
Entry Details
PCBioAssay
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM32276(MLS000520261 | cid_9550179 | SMR000130674 | 4-(but...)
Affinity DataEC50:  1.04E+3nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2011
Entry Details
PCBioAssay
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM203870(7-(3-((3-Acetyl-4-boronophenoxy)methyl)-1,5-dimeth...)
Affinity DataEC50:  1.17E+3nMAssay Description:Inhibition of MCL-1 in human MOLP8 cells assessed as increase in caspase 3/7 activationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM33165(3-chloro-4-(3-methoxyphenoxy)-1-(4-methoxyphenyl)-...)
Affinity DataEC50:  1.65E+3nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2011
Entry Details
PCBioAssay
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM32268(SMR000026607 | 6,7-dimethoxy-4-[(3-methoxypropyl)a...)
Affinity DataEC50:  1.74E+3nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2011
Entry Details
PCBioAssay
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM33057(SMR000076237 | 6-methyl-2-naphthalen-1-ylbenzotria...)
Affinity DataEC50:  1.75E+3nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2011
Entry Details
PCBioAssay
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM32282(cid_1930774 | methyl 2-[[2-amino-1-(3-ethoxypropyl...)
Affinity DataEC50:  1.85E+3nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2011
Entry Details
PCBioAssay
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM32270(6,7-dimethoxy-4-(2-oxolanylmethylamino)-1H-quinazo...)
Affinity DataEC50:  1.90E+3nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2011
Entry Details
PCBioAssay
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM33133(SMR000225370 | MLS000702137 | cid_15945005 | 3-(4-...)
Affinity DataEC50:  2.04E+3nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2011
Entry Details
PCBioAssay
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50397586(CHEMBL2171488)
Affinity DataEC50:  2.10E+3nMAssay Description:Inhibition of GST-tagged recombinant Mcl1 interaction with biotinylated Bim peptide by ELISA based competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM32287((5E)-5-[[5-(2-chlorophenyl)furan-2-yl]methylidene]...)
Affinity DataEC50:  2.14E+3nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2011
Entry Details
PCBioAssay
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM33057(SMR000076237 | 6-methyl-2-naphthalen-1-ylbenzotria...)
Affinity DataEC50:  2.25E+3nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2011
Entry Details
PCBioAssay
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50397583(CHEMBL2171509)
Affinity DataEC50:  2.30E+3nMAssay Description:Inhibition of GST-tagged recombinant Mcl1 interaction with biotinylated Bim peptide by ELISA based competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM32265(cid_3237310 | MLS000045007 | SMR000026611 | 4-[(3-...)
Affinity DataEC50:  2.54E+3nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2011
Entry Details
PCBioAssay
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM32296(1-p-Tolyl-3-(5-p-tolyl-furan-2-yl)-propenone | (E)...)
Affinity DataEC50:  2.61E+3nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2011
Entry Details
PCBioAssay
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM203872(7-(3-((3-Acetylphenoxy)methyl)-1,5-dimethyl-1H-pyr...)
Affinity DataEC50:  2.70E+3nMAssay Description:Inhibition of MCL-1 in human MOLP8 cells assessed as increase in caspase 3/7 activationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM32288(isonicotinaldehyde (1,1-dioxido-1,2-benzisothiazol...)
Affinity DataEC50:  2.74E+3nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2011
Entry Details
PCBioAssay
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM32281(6-(3,4-Dimethoxy-phenyl)-3-furan-2-yl-7H-[1,2,4]tr...)
Affinity DataEC50:  2.94E+3nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2011
Entry Details
PCBioAssay
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM32283(MLS000595323 | cid_1930463 | 2-[[[2-amino-1-(3-met...)
Affinity DataEC50:  3.12E+3nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2011
Entry Details
PCBioAssay
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM46302(MLS000083668 | SMR000047693 | cid_666339)
Affinity DataEC50:  3.18E+3nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2011
Entry Details
PCBioAssay
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50397587(CHEMBL2171489)
Affinity DataEC50:  3.50E+3nMAssay Description:Inhibition of GST-tagged recombinant Mcl1 interaction with biotinylated Bim peptide by ELISA based competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM33066(cid_1002248 | 2,5-dichloro-3-[2-(dimethylamino)-5-...)
Affinity DataEC50:  3.71E+3nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2011
Entry Details
PCBioAssay
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM32330(cid_16196155 | MLS001011168 | (2Z)-2-(5-fluoranyl-...)
Affinity DataEC50:  3.83E+3nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2011
Entry Details
PCBioAssay
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM32279(cid_1192535 | SMR000129741 | 4-(4-ethoxycarbonylan...)
Affinity DataEC50:  4.52E+3nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2011
Entry Details
PCBioAssay
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM32267(cid_3239316 | 6,7-dimethoxy-4-[(2-methoxyethyl)ami...)
Affinity DataEC50:  4.54E+3nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2011
Entry Details
PCBioAssay
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM32285((4E)-2-methoxy-4-[[2-([1,2,4]triazolo[3,4-a]phthal...)
Affinity DataEC50:  5.05E+3nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2011
Entry Details
PCBioAssay
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM32294((1E,2E)-3-phenylacrylaldehyde (1,1-dioxido-1,2-ben...)
Affinity DataEC50:  5.53E+3nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2011
Entry Details
PCBioAssay
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM43203(SMR000218122 | 2-[[5-(4-chlorophenyl)-4-phenyl-1,2...)
Affinity DataEC50:  5.71E+3nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2011
Entry Details
PCBioAssay
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM32323(SMR000324305 | MLS000685782 | N-[3-(3-methyl-[1,2,...)
Affinity DataEC50:  5.76E+3nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2011
Entry Details
PCBioAssay
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM32311(SMR000259554 | MLS000390291 | cid_7125637)
Affinity DataEC50:  5.86E+3nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2011
Entry Details
PCBioAssay
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM32303(4-chloro-3-nitrobenzoic acid [6-[[(4,6-dimethyl-2-...)
Affinity DataEC50:  5.92E+3nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2011
Entry Details
PCBioAssay
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM32310(SMR000259502 | MLS000390238 | cid_6311834)
Affinity DataEC50:  6.00E+3nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2011
Entry Details
PCBioAssay
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM32327(cid_1482788 | 4-azanyl-6,7-dimethoxy-3-(3-morpholi...)
Affinity DataEC50:  6.14E+3nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2011
Entry Details
PCBioAssay
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM43204(SMR000335052 | 1-(2-cyano-4,5-dimethoxyphenyl)-3-(...)
Affinity DataEC50:  7.11E+3nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2011
Entry Details
PCBioAssay
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM43203(SMR000218122 | 2-[[5-(4-chlorophenyl)-4-phenyl-1,2...)
Affinity DataEC50:  7.75E+3nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2011
Entry Details
PCBioAssay
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM33123(N-[(5-bromanyl-2-phenylmethoxy-phenyl)methylidenea...)
Affinity DataEC50:  7.78E+3nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2011
Entry Details
PCBioAssay
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM33087(2,3-bis(furan-2-yl)-N-(phenylmethyl)quinoxaline-6-...)
Affinity DataEC50:  7.82E+3nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2011
Entry Details
PCBioAssay
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50397585(CHEMBL2171491)
Affinity DataEC50:  7.90E+3nMAssay Description:Inhibition of GST-tagged recombinant Mcl1 interaction with biotinylated Bim peptide by ELISA based competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM32300(4-(2-methyl-3-imidazo[1,2-a]pyrimidinyl)-N-phenyl-...)
Affinity DataEC50:  8.97E+3nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2011
Entry Details
PCBioAssay
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM32316(MLS000704595 | SMR000231990 | ethyl 6-chloro-2,7-d...)
Affinity DataEC50:  9.29E+3nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2011
Entry Details
PCBioAssay
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM32263(MLS000082991 | SMR000046672 | cid_665473 | 3-(5-me...)
Affinity DataEC50:  9.39E+3nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2011
Entry Details
PCBioAssay
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM33134(cid_15945006 | SMR000225371 | MLS000702136 | 5-(4-...)
Affinity DataEC50:  9.74E+3nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2011
Entry Details
PCBioAssay
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50547480(CHEMBL4790235)
Affinity DataEC50: >1.00E+4nMAssay Description:Binding affinity to full length His-tagged Mcl1 (unknown origin) preincubated for 30 min followed by 5-FAM Bid-BH3 addition and measured after 20 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
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