Compile Data Set for Download or QSAR
maximum 50k data
Found 31 of ic50 data for polymerid = 4019
Target11-beta-hydroxysteroid dehydrogenase 1 [23-292,A23S,F278E](Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM32522(pyridine amide, 30)
Affinity DataIC50:  0.100nMpH: 6.5 T: 2°CAssay Description:11beta-HSD1 microsomes isolated from HEK 293 cells over-expressing human 11beta-HSD1 were incubated with the substrate cortisone and cofactor NADPH a...More data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1 [23-292,A23S,F278E](Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM32520(pyridine amide, 28)
Affinity DataIC50:  1.10nMpH: 6.5 T: 2°CAssay Description:11beta-HSD1 microsomes isolated from HEK 293 cells over-expressing human 11beta-HSD1 were incubated with the substrate cortisone and cofactor NADPH a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1 [23-292,A23S,F278E](Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM32521(pyridine amide, 29)
Affinity DataIC50:  1.10nMpH: 6.5 T: 2°CAssay Description:11beta-HSD1 microsomes isolated from HEK 293 cells over-expressing human 11beta-HSD1 were incubated with the substrate cortisone and cofactor NADPH a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1 [23-292,A23S,F278E](Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM32527(pyridine amide, 35)
Affinity DataIC50:  1.70nMT: 2°CAssay Description:11beta-HSD1 microsomes isolated from HEK 293 cells over-expressing human 11beta-HSD1 were incubated with the substrate cortisone and cofactor NADPH a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1 [23-292,A23S,F278E](Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM32526(pyridine amide, 34)
Affinity DataIC50:  2nMT: 2°CAssay Description:11beta-HSD1 microsomes isolated from HEK 293 cells over-expressing human 11beta-HSD1 were incubated with the substrate cortisone and cofactor NADPH a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1 [23-292,A23S,F278E](Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM32523(pyridine amide, 31)
Affinity DataIC50:  2nMpH: 6.5 T: 2°CAssay Description:11beta-HSD1 microsomes isolated from HEK 293 cells over-expressing human 11beta-HSD1 were incubated with the substrate cortisone and cofactor NADPH a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1 [23-292,A23S,F278E](Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM32508(pyridine amide, 23)
Affinity DataIC50:  2.5nMpH: 6.5 T: 2°CAssay Description:11beta-HSD1 microsomes isolated from HEK 293 cells over-expressing human 11beta-HSD1 were incubated with the substrate cortisone and cofactor NADPH a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1 [23-292,A23S,F278E](Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM32519(pyridine amide, 27)
Affinity DataIC50:  2.90nMpH: 6.5 T: 2°CAssay Description:11beta-HSD1 microsomes isolated from HEK 293 cells over-expressing human 11beta-HSD1 were incubated with the substrate cortisone and cofactor NADPH a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1 [23-292,A23S,F278E](Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM32524(pyridine amide, 32)
Affinity DataIC50:  3.60nMpH: 6.5 T: 2°CAssay Description:11beta-HSD1 microsomes isolated from HEK 293 cells over-expressing human 11beta-HSD1 were incubated with the substrate cortisone and cofactor NADPH a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1 [23-292,A23S,F278E](Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM32529(pyridine amide, 37)
Affinity DataIC50:  4.60nMT: 2°CAssay Description:11beta-HSD1 microsomes isolated from HEK 293 cells over-expressing human 11beta-HSD1 were incubated with the substrate cortisone and cofactor NADPH a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1 [23-292,A23S,F278E](Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM32525(pyridine amide, 33)
Affinity DataIC50:  4.70nMpH: 6.5 T: 2°CAssay Description:11beta-HSD1 microsomes isolated from HEK 293 cells over-expressing human 11beta-HSD1 were incubated with the substrate cortisone and cofactor NADPH a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1 [23-292,A23S,F278E](Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM32528(pyridine amide, 36)
Affinity DataIC50:  6.5nMT: 2°CAssay Description:11beta-HSD1 microsomes isolated from HEK 293 cells over-expressing human 11beta-HSD1 were incubated with the substrate cortisone and cofactor NADPH a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1 [23-292,A23S,F278E](Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM32512(pyridine amide, 6)
Affinity DataIC50:  7.20nMpH: 6.5 T: 2°CAssay Description:11beta-HSD1 microsomes isolated from HEK 293 cells over-expressing human 11beta-HSD1 were incubated with the substrate cortisone and cofactor NADPH a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1 [23-292,A23S,F278E](Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM32507(pyridine amide, 22)
Affinity DataIC50:  11nMpH: 6.5 T: 2°CAssay Description:11beta-HSD1 microsomes isolated from HEK 293 cells over-expressing human 11beta-HSD1 were incubated with the substrate cortisone and cofactor NADPH a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1 [23-292,A23S,F278E](Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM32518(pyridine amide, 9)
Affinity DataIC50:  17nMpH: 6.5 T: 2°CAssay Description:11beta-HSD1 microsomes isolated from HEK 293 cells over-expressing human 11beta-HSD1 were incubated with the substrate cortisone and cofactor NADPH a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1 [23-292,A23S,F278E](Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM32506(pyridine amide, 21)
Affinity DataIC50:  21nMpH: 6.5 T: 2°CAssay Description:11beta-HSD1 microsomes isolated from HEK 293 cells over-expressing human 11beta-HSD1 were incubated with the substrate cortisone and cofactor NADPH a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1 [23-292,A23S,F278E](Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM32500(pyridine amide, 15)
Affinity DataIC50:  22nMpH: 6.5 T: 2°CAssay Description:11beta-HSD1 microsomes isolated from HEK 293 cells over-expressing human 11beta-HSD1 were incubated with the substrate cortisone and cofactor NADPH a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1 [23-292,A23S,F278E](Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM32499(pyridine amide, 8)
Affinity DataIC50:  35nMpH: 6.5 T: 2°CAssay Description:11beta-HSD1 microsomes isolated from HEK 293 cells over-expressing human 11beta-HSD1 were incubated with the substrate cortisone and cofactor NADPH a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1 [23-292,A23S,F278E](Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM32513(pyridine amide, 7)
Affinity DataIC50:  79nMpH: 6.5 T: 2°CAssay Description:11beta-HSD1 microsomes isolated from HEK 293 cells over-expressing human 11beta-HSD1 were incubated with the substrate cortisone and cofactor NADPH a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1 [23-292,A23S,F278E](Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM32501(pyridine amide, 16)
Affinity DataIC50:  106nMpH: 6.5 T: 2°CAssay Description:11beta-HSD1 microsomes isolated from HEK 293 cells over-expressing human 11beta-HSD1 were incubated with the substrate cortisone and cofactor NADPH a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1 [23-292,A23S,F278E](Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM32514(pyridine amide, 11)
Affinity DataIC50:  218nMpH: 6.5 T: 2°CAssay Description:11beta-HSD1 microsomes isolated from HEK 293 cells over-expressing human 11beta-HSD1 were incubated with the substrate cortisone and cofactor NADPH a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1 [23-292,A23S,F278E](Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM32509(pyridine amide, 24)
Affinity DataIC50:  220nMpH: 6.5 T: 2°CAssay Description:11beta-HSD1 microsomes isolated from HEK 293 cells over-expressing human 11beta-HSD1 were incubated with the substrate cortisone and cofactor NADPH a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1 [23-292,A23S,F278E](Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM32515(pyridine amide, 12)
Affinity DataIC50:  282nMpH: 6.5 T: 2°CAssay Description:11beta-HSD1 microsomes isolated from HEK 293 cells over-expressing human 11beta-HSD1 were incubated with the substrate cortisone and cofactor NADPH a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1 [23-292,A23S,F278E](Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM32502(pyridine amide, 17)
Affinity DataIC50:  319nMpH: 6.5 T: 2°CAssay Description:11beta-HSD1 microsomes isolated from HEK 293 cells over-expressing human 11beta-HSD1 were incubated with the substrate cortisone and cofactor NADPH a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1 [23-292,A23S,F278E](Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM32516(pyridine amide, 13)
Affinity DataIC50:  381nMpH: 6.5 T: 2°CAssay Description:11beta-HSD1 microsomes isolated from HEK 293 cells over-expressing human 11beta-HSD1 were incubated with the substrate cortisone and cofactor NADPH a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1 [23-292,A23S,F278E](Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM32503(pyridine amide, 18)
Affinity DataIC50:  2.05E+3nMpH: 6.5 T: 2°CAssay Description:11beta-HSD1 microsomes isolated from HEK 293 cells over-expressing human 11beta-HSD1 were incubated with the substrate cortisone and cofactor NADPH a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1 [23-292,A23S,F278E](Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM32504(pyridine amide, 19)
Affinity DataIC50:  2.13E+3nMpH: 6.5 T: 2°CAssay Description:11beta-HSD1 microsomes isolated from HEK 293 cells over-expressing human 11beta-HSD1 were incubated with the substrate cortisone and cofactor NADPH a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1 [23-292,A23S,F278E](Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM32505(pyridine amide, 20)
Affinity DataIC50:  2.14E+3nMpH: 6.5 T: 2°CAssay Description:11beta-HSD1 microsomes isolated from HEK 293 cells over-expressing human 11beta-HSD1 were incubated with the substrate cortisone and cofactor NADPH a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1 [23-292,A23S,F278E](Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM32510(pyridine amide, 25)
Affinity DataIC50:  2.35E+3nMpH: 6.5 T: 2°CAssay Description:11beta-HSD1 microsomes isolated from HEK 293 cells over-expressing human 11beta-HSD1 were incubated with the substrate cortisone and cofactor NADPH a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1 [23-292,A23S,F278E](Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM32517(pyridine amide, 14)
Affinity DataIC50:  4.67E+3nMpH: 6.5 T: 2°CAssay Description:11beta-HSD1 microsomes isolated from HEK 293 cells over-expressing human 11beta-HSD1 were incubated with the substrate cortisone and cofactor NADPH a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1 [23-292,A23S,F278E](Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM32511(pyridine amide, 26)
Affinity DataIC50: >1.00E+4nMpH: 6.5 T: 2°CAssay Description:11beta-HSD1 microsomes isolated from HEK 293 cells over-expressing human 11beta-HSD1 were incubated with the substrate cortisone and cofactor NADPH a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed