Compile Data Set for Download or QSAR
Report error Found 215 of ic50 for UniProtKB: P15559
TargetNAD(P)H dehydrogenase [quinone] 1(Human)
University of Manchester

LigandPNGBDBM35536(symmetric dicoumarol analogue, 12)
Affinity DataIC50: 0.180nMpH: 7.5Assay Description:Recombinant human NQO1 was obtained from Sigma and diluted in 50 mM phosphate buffer to give an absorbance of 0.1 at 550 nm; 5 uL of this solution wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2009
Entry Details Article
PubMed
TargetNAD(P)H dehydrogenase [quinone] 1(Human)
University of Manchester

LigandPNGBDBM35534(symmetric dicoumarol analogue, 10)
Affinity DataIC50: 0.410nMpH: 7.5Assay Description:Recombinant human NQO1 was obtained from Sigma and diluted in 50 mM phosphate buffer to give an absorbance of 0.1 at 550 nm; 5 uL of this solution wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2009
Entry Details Article
PubMed
TargetNAD(P)H dehydrogenase [quinone] 1(Human)
University of Manchester

LigandPNGBDBM35537(symmetric dicoumarol analogue, 13)
Affinity DataIC50: 0.420nMpH: 7.5Assay Description:Recombinant human NQO1 was obtained from Sigma and diluted in 50 mM phosphate buffer to give an absorbance of 0.1 at 550 nm; 5 uL of this solution wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2009
Entry Details Article
PubMed
TargetNAD(P)H dehydrogenase [quinone] 1(Human)
University of Manchester

LigandPNGBDBM35544(4-hydroxy-2H-chromen-2-one core, 20)
Affinity DataIC50: 2.20nMpH: 7.5Assay Description:Recombinant human NQO1 was obtained from Sigma and diluted in 50 mM phosphate buffer to give an absorbance of 0.1 at 550 nm; 5 uL of this solution wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2009
Entry Details Article
PubMed
TargetNAD(P)H dehydrogenase [quinone] 1(Human)
University of Manchester

LigandPNGBDBM35541(4-hydroxy-2H-chromen-2-one core, 17)
Affinity DataIC50: 2.5nMpH: 7.5Assay Description:Recombinant human NQO1 was obtained from Sigma and diluted in 50 mM phosphate buffer to give an absorbance of 0.1 at 550 nm; 5 uL of this solution wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2009
Entry Details Article
PubMed
TargetNAD(P)H dehydrogenase [quinone] 1(Human)
University of Manchester

LigandPNGBDBM35525(dicoumarol | 3,3''''-methylenebis(4-hydroxycoumari...)
Affinity DataIC50: 2.60nMpH: 7.5Assay Description:Recombinant human NQO1 was obtained from Sigma and diluted in 50 mM phosphate buffer to give an absorbance of 0.1 at 550 nm; 5 uL of this solution wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2009
Entry Details Article
PubMed
TargetNAD(P)H dehydrogenase [quinone] 1(Human)
University of Manchester

LigandPNGBDBM35527(symmetric dicoumarol analogue, 3)
Affinity DataIC50: 2.80nMpH: 7.5Assay Description:Recombinant human NQO1 was obtained from Sigma and diluted in 50 mM phosphate buffer to give an absorbance of 0.1 at 550 nm; 5 uL of this solution wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2009
Entry Details Article
PubMed
TargetNAD(P)H dehydrogenase [quinone] 1(Human)
University of Manchester

LigandPNGBDBM35531(symmetric dicoumarol analogue, 7)
Affinity DataIC50: 3.80nMpH: 7.5Assay Description:Recombinant human NQO1 was obtained from Sigma and diluted in 50 mM phosphate buffer to give an absorbance of 0.1 at 550 nm; 5 uL of this solution wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2009
Entry Details Article
PubMed
TargetNAD(P)H dehydrogenase [quinone] 1(Human)
University of Manchester

LigandPNGBDBM35530(symmetric dicoumarol analogue, 6)
Affinity DataIC50: 4.5nMpH: 7.5Assay Description:Recombinant human NQO1 was obtained from Sigma and diluted in 50 mM phosphate buffer to give an absorbance of 0.1 at 550 nm; 5 uL of this solution wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2009
Entry Details Article
PubMed
TargetNAD(P)H dehydrogenase [quinone] 1(Human)
University of Manchester

LigandPNGBDBM35533(symmetric dicoumarol analogue, 9)
Affinity DataIC50: 4.90nMpH: 7.5Assay Description:Recombinant human NQO1 was obtained from Sigma and diluted in 50 mM phosphate buffer to give an absorbance of 0.1 at 550 nm; 5 uL of this solution wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2009
Entry Details Article
PubMed
TargetNAD(P)H dehydrogenase [quinone] 1(Human)
University of Manchester

LigandPNGBDBM35525(dicoumarol | 3,3''''-methylenebis(4-hydroxycoumari...)
Affinity DataIC50: 5nMAssay Description:Inhibition of human recombinant NQO1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetNAD(P)H dehydrogenase [quinone] 1(Human)
University of Manchester

LigandPNGBDBM50055714(CHEMBL312727 | CHEMBL238291 | 3-(4,7-dihydroxy-2-o...)
Affinity DataIC50: 5nMAssay Description:Inhibition of human recombinant NQO1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetNAD(P)H dehydrogenase [quinone] 1(Human)
University of Manchester

LigandPNGBDBM35529(symmetric dicoumarol analogue, 5)
Affinity DataIC50: 6nMpH: 7.5Assay Description:Recombinant human NQO1 was obtained from Sigma and diluted in 50 mM phosphate buffer to give an absorbance of 0.1 at 550 nm; 5 uL of this solution wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2009
Entry Details Article
PubMed
TargetNAD(P)H dehydrogenase [quinone] 1(Human)
University of Manchester

LigandPNGBDBM35547(4-hydroxy-2H-chromen-2-one core, 23)
Affinity DataIC50: 6nMpH: 7.5Assay Description:Recombinant human NQO1 was obtained from Sigma and diluted in 50 mM phosphate buffer to give an absorbance of 0.1 at 550 nm; 5 uL of this solution wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2009
Entry Details Article
PubMed
TargetNAD(P)H dehydrogenase [quinone] 1(Human)
University of Manchester

LigandPNGBDBM35543(4-hydroxy-2H-chromen-2-one core, 19)
Affinity DataIC50: 6.30nMpH: 7.5Assay Description:Recombinant human NQO1 was obtained from Sigma and diluted in 50 mM phosphate buffer to give an absorbance of 0.1 at 550 nm; 5 uL of this solution wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2009
Entry Details Article
PubMed
TargetNAD(P)H dehydrogenase [quinone] 1(Human)
University of Manchester

LigandPNGBDBM35546(4-hydroxy-2H-chromen-2-one core, 22)
Affinity DataIC50: 6.30nMpH: 7.5Assay Description:Recombinant human NQO1 was obtained from Sigma and diluted in 50 mM phosphate buffer to give an absorbance of 0.1 at 550 nm; 5 uL of this solution wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2009
Entry Details Article
PubMed
TargetNAD(P)H dehydrogenase [quinone] 1(Human)
University of Manchester

LigandPNGBDBM35540(4-hydroxy-2H-chromen-2-one core, 16)
Affinity DataIC50: 7.70nMpH: 7.5Assay Description:Recombinant human NQO1 was obtained from Sigma and diluted in 50 mM phosphate buffer to give an absorbance of 0.1 at 550 nm; 5 uL of this solution wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetNAD(P)H dehydrogenase [quinone] 1(Human)
University of Manchester

LigandPNGBDBM35532(symmetric dicoumarol analogue, 8)
Affinity DataIC50: 9nMpH: 7.5Assay Description:Recombinant human NQO1 was obtained from Sigma and diluted in 50 mM phosphate buffer to give an absorbance of 0.1 at 550 nm; 5 uL of this solution wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2009
Entry Details Article
PubMed
TargetNAD(P)H dehydrogenase [quinone] 1(Human)
University of Manchester

LigandPNGBDBM35552(4-hydroxy-2H-chromen-2-one core, 29)
Affinity DataIC50: 9.90nMpH: 7.5Assay Description:Recombinant human NQO1 was obtained from Sigma and diluted in 50 mM phosphate buffer to give an absorbance of 0.1 at 550 nm; 5 uL of this solution wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2009
Entry Details Article
PubMed
TargetNAD(P)H dehydrogenase [quinone] 1(Human)
University of Manchester

LigandPNGBDBM35528(symmetric dicoumarol analogue, 4)
Affinity DataIC50: 11nMpH: 7.5Assay Description:Recombinant human NQO1 was obtained from Sigma and diluted in 50 mM phosphate buffer to give an absorbance of 0.1 at 550 nm; 5 uL of this solution wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2009
Entry Details Article
PubMed
TargetNAD(P)H dehydrogenase [quinone] 1(Human)
University of Manchester

LigandPNGBDBM35526(symmetric dicoumarol analogue, 2)
Affinity DataIC50: 14nMpH: 7.5Assay Description:Recombinant human NQO1 was obtained from Sigma and diluted in 50 mM phosphate buffer to give an absorbance of 0.1 at 550 nm; 5 uL of this solution wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2009
Entry Details Article
PubMed
TargetNAD(P)H dehydrogenase [quinone] 1(Human)
University of Manchester

LigandPNGBDBM35550(4-hydroxy-2H-chromen-2-one core, 26)
Affinity DataIC50: 14nMpH: 7.5Assay Description:Recombinant human NQO1 was obtained from Sigma and diluted in 50 mM phosphate buffer to give an absorbance of 0.1 at 550 nm; 5 uL of this solution wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2009
Entry Details Article
PubMed
TargetNAD(P)H dehydrogenase [quinone] 1(Human)
University of Manchester

LigandPNGBDBM35548(4-hydroxy-2H-chromen-2-one core, 24)
Affinity DataIC50: 15nMpH: 7.5Assay Description:Recombinant human NQO1 was obtained from Sigma and diluted in 50 mM phosphate buffer to give an absorbance of 0.1 at 550 nm; 5 uL of this solution wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2009
Entry Details Article
PubMed
TargetNAD(P)H dehydrogenase [quinone] 1(Human)
University of Manchester

LigandPNGBDBM35549(4-hydroxy-2H-chromen-2-one core, 25)
Affinity DataIC50: 24nMpH: 7.5Assay Description:Recombinant human NQO1 was obtained from Sigma and diluted in 50 mM phosphate buffer to give an absorbance of 0.1 at 550 nm; 5 uL of this solution wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2009
Entry Details Article
PubMed
TargetNAD(P)H dehydrogenase [quinone] 1(Human)
University of Manchester

LigandPNGBDBM35551(4-hydroxy-2H-chromen-2-one core, 28)
Affinity DataIC50: 31nMpH: 7.5Assay Description:Recombinant human NQO1 was obtained from Sigma and diluted in 50 mM phosphate buffer to give an absorbance of 0.1 at 550 nm; 5 uL of this solution wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2009
Entry Details Article
PubMed
TargetNAD(P)H dehydrogenase [quinone] 1(Human)
University of Manchester

LigandPNGBDBM35545(4-hydroxy-2H-chromen-2-one core, 21)
Affinity DataIC50: 35nMpH: 7.5Assay Description:Recombinant human NQO1 was obtained from Sigma and diluted in 50 mM phosphate buffer to give an absorbance of 0.1 at 550 nm; 5 uL of this solution wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2009
Entry Details Article
PubMed
TargetNAD(P)H dehydrogenase [quinone] 1(Human)
University of Manchester

LigandPNGBDBM35527(symmetric dicoumarol analogue, 3)
Affinity DataIC50: 38nMpH: 7.5 T: 2°CAssay Description:Recombinant human NQO1 was obtained from Sigma and diluted in 50 mM phosphate buffer to give an absorbance of 0.1 at 550 nm; 5 uL of this solution wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2009
Entry Details Article
PubMed
TargetNAD(P)H dehydrogenase [quinone] 1(Human)
University of Manchester

LigandPNGBDBM35542(4-hydroxy-2H-chromen-2-one core, 18)
Affinity DataIC50: 39nMpH: 7.5Assay Description:Recombinant human NQO1 was obtained from Sigma and diluted in 50 mM phosphate buffer to give an absorbance of 0.1 at 550 nm; 5 uL of this solution wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2009
Entry Details Article
PubMed
TargetNAD(P)H dehydrogenase [quinone] 1(Human)
University of Manchester

LigandPNGBDBM35535(symmetric dicoumarol analogue, 11)
Affinity DataIC50: 62nMpH: 7.5Assay Description:Recombinant human NQO1 was obtained from Sigma and diluted in 50 mM phosphate buffer to give an absorbance of 0.1 at 550 nm; 5 uL of this solution wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2009
Entry Details Article
PubMed
TargetNAD(P)H dehydrogenase [quinone] 1(Human)
University of Manchester

LigandPNGBDBM50309775(5-(isopentylamino)-6H-[1,2,3]triazolo[4,5,1-de]acr...)
Affinity DataIC50: 92nMAssay Description:Inhibition of human recombinant NQO1 by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetNAD(P)H dehydrogenase [quinone] 1(Human)
University of Manchester

LigandPNGBDBM50309777(5-(2-(dimethylamino)ethylamino)-6H-[1,2,3]triazolo...)
Affinity DataIC50: 94nMAssay Description:Inhibition of human recombinant NQO1 by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetNAD(P)H dehydrogenase [quinone] 1(Human)
University of Manchester

LigandPNGBDBM35537(symmetric dicoumarol analogue, 13)
Affinity DataIC50: 96nMpH: 7.5 T: 2°CAssay Description:Recombinant human NQO1 was obtained from Sigma and diluted in 50 mM phosphate buffer to give an absorbance of 0.1 at 550 nm; 5 uL of this solution wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2009
Entry Details Article
PubMed
TargetNAD(P)H dehydrogenase [quinone] 1(Human)
University of Manchester

LigandPNGBDBM50055695(CHEMBL312008 | Dicoumarol derivative, 6 | CHEMBL23...)
Affinity DataIC50: 100nMAssay Description:Inhibition of human recombinant NQO1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetNAD(P)H dehydrogenase [quinone] 1(Human)
University of Manchester

LigandPNGBDBM50309771(8-bromo-5-(isopentylamino)-6H-[1,2,3]triazolo[4,5,...)
Affinity DataIC50: 107nMAssay Description:Inhibition of human recombinant NQO1 by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetNAD(P)H dehydrogenase [quinone] 1(Human)
University of Manchester

LigandPNGBDBM506(3-({4-[bis(4-hydroxy-2-oxo-2H-chromen-3-yl)methyl]...)
Affinity DataIC50: 110nMAssay Description:Inhibition of human recombinant NQO1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetNAD(P)H dehydrogenase [quinone] 1(Human)
University of Manchester

LigandPNGBDBM50309766(5-(2-(dimethylamino)ethylamino)-8-methoxy-6H-[1,2,...)
Affinity DataIC50: 111nMAssay Description:Inhibition of human recombinant NQO1 by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetNAD(P)H dehydrogenase [quinone] 1(Human)
University of Manchester

LigandPNGBDBM50055694(CHEMBL316387 | 4-hydroxy-3-[4-hydroxy-2-oxo-2H-3-c...)
Affinity DataIC50: 140nMAssay Description:Inhibition of human recombinant NQO1 in presence of BSAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetNAD(P)H dehydrogenase [quinone] 1(Human)
University of Manchester

LigandPNGBDBM2566(3-benzyl-4-hydroxy-2H-chromen-2-one | JMC527142 Co...)
Affinity DataIC50: 144nMpH: 7.5Assay Description:Recombinant human NQO1 was obtained from Sigma and diluted in 50 mM phosphate buffer to give an absorbance of 0.1 at 550 nm; 5 uL of this solution wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2009
Entry Details Article
PubMed
TargetNAD(P)H dehydrogenase [quinone] 1(Human)
University of Manchester

LigandPNGBDBM50309774(5-(3-hydroxypropylamino)-8-bromo-6H-[1,2,3]triazol...)
Affinity DataIC50: 145nMAssay Description:Inhibition of human recombinant NQO1 by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetNAD(P)H dehydrogenase [quinone] 1(Human)
University of Manchester

LigandPNGBDBM50226820(3-((9H-fluoren-3-yl)(4-hydroxy-2-oxo-2H-chromen-3-...)
Affinity DataIC50: 150nMAssay Description:Inhibition of human recombinant NQO1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetNAD(P)H dehydrogenase [quinone] 1(Human)
University of Manchester

LigandPNGBDBM35541(4-hydroxy-2H-chromen-2-one core, 17)
Affinity DataIC50: 167nMpH: 7.5 T: 2°CAssay Description:Recombinant human NQO1 was obtained from Sigma and diluted in 50 mM phosphate buffer to give an absorbance of 0.1 at 550 nm; 5 uL of this solution wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2009
Entry Details Article
PubMed
TargetNAD(P)H dehydrogenase [quinone] 1(Human)
University of Manchester

LigandPNGBDBM50309768(5-(2-(dimethylamino)ethylamino)-8-fluoro-6H-[1,2,3...)
Affinity DataIC50: 188nMAssay Description:Inhibition of human recombinant NQO1 by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetNAD(P)H dehydrogenase [quinone] 1(Human)
University of Manchester

LigandPNGBDBM35552(4-hydroxy-2H-chromen-2-one core, 29)
Affinity DataIC50: 192nMpH: 7.5 T: 2°CAssay Description:Recombinant human NQO1 was obtained from Sigma and diluted in 50 mM phosphate buffer to give an absorbance of 0.1 at 550 nm; 5 uL of this solution wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2009
Entry Details Article
PubMed
TargetNAD(P)H dehydrogenase [quinone] 1(Human)
University of Manchester

LigandPNGBDBM50055689(CHEMBL32926 | 12-(4-hydroxy-2-oxochromen-3-yl)-12H...)
Affinity DataIC50: 200nMAssay Description:Inhibition of human recombinant NQO1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetNAD(P)H dehydrogenase [quinone] 1(Human)
University of Manchester

LigandPNGBDBM50309776(5-(3-hydroxypropylamino)-6H-[1,2,3]triazolo[4,5,1-...)
Affinity DataIC50: 203nMAssay Description:Inhibition of human recombinant NQO1 by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetNAD(P)H dehydrogenase [quinone] 1(Human)
University of Manchester

LigandPNGBDBM50309773(5-(3-hydroxypropylamino)-8-methoxy-6H-[1,2,3]triaz...)
Affinity DataIC50: 206nMAssay Description:Inhibition of human recombinant NQO1 by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetNAD(P)H dehydrogenase [quinone] 1(Human)
University of Manchester

LigandPNGBDBM50226816(4-hydroxy-3-((4-hydroxy-2-oxo-2H-chromen-3-yl)(4-m...)
Affinity DataIC50: 220nMAssay Description:Inhibition of human recombinant NQO1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetNAD(P)H dehydrogenase [quinone] 1(Human)
University of Manchester

LigandPNGBDBM50466800(CHEMBL4290035)
Affinity DataIC50: 230nMAssay Description:Inhibition of recombinant human NQO1 assessed as reduction in oxidation of NADPH to NADP+ using b-lap as substrate and NADPH in presence of 0.14% (w/...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetNAD(P)H dehydrogenase [quinone] 1(Human)
University of Manchester

LigandPNGBDBM35534(symmetric dicoumarol analogue, 10)
Affinity DataIC50: 233nMpH: 7.5 T: 2°CAssay Description:Recombinant human NQO1 was obtained from Sigma and diluted in 50 mM phosphate buffer to give an absorbance of 0.1 at 550 nm; 5 uL of this solution wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2009
Entry Details Article
PubMed
TargetNAD(P)H dehydrogenase [quinone] 1(Human)
University of Manchester

LigandPNGBDBM50055711(CHEMBL32711 | CHEMBL437179 | 3-[4-di(4,7-dihydroxy...)
Affinity DataIC50: 250nMAssay Description:Inhibition of human recombinant NQO1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
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