Compile Data Set for Download or QSAR
Report error Found 583 of ec50 data for polymerid = 4341
TargetAdenosine receptor A2b(Human)
Monash University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50594320BDBM50594320(CHEMBL5177040)
Affinity DataEC50:  0.324nMAssay Description:Agonist activity at A2BR in human NHVCF cells assessed as cAMP accumulation incubated for 30 mins by LANCE cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetAdenosine receptor A2b(Human)
Monash University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50594320BDBM50594320(CHEMBL5177040)
Affinity DataEC50:  0.380nMAssay Description:Agonist activity at human A2B receptor expressed in Flp-In-CHO cells assessed as cAMP accumulation incubated for 10 mins in presence of forskolin by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetAdenosine receptor A2b(Human)
Monash University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 729456BDBM729456(Preparation of 5-Cyclobutyl-N-[4-(2-Fluorophenyl)-...)
Affinity DataEC50:  2.20nMAssay Description:In all radioligand binding experiments, the samples were incubated in a final volume of 0.1 ml of binding buffer for 60 minutes at 25° C. and then fi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/31/2025
Entry Details
US Patent

TargetAdenosine receptor A2b(Human)
Monash University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50385957BDBM50385957(CHEMBL2042297)
Affinity DataEC50:  2.30nMAssay Description:Agonist activity at human adenosine A2B receptor expressed in CHO cells assessed as increase in intracellular cAMP level after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
Monash University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 191805BDBM191805(US9187428, 33)
Affinity DataEC50:  3.90nMpH: 7.4 T: 2°CAssay Description:The stock cultures are grown, at 37° C. and under 5% CO2, in DMEM/F12 medium containing 10% FCS (fetal calf serum) and in each case split 1:10 af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2016
Entry Details
US Patent

TargetAdenosine receptor A2b(Human)
Monash University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50263201BDBM50263201(CHEMBL4104819)
Affinity DataEC50:  4.60nMAssay Description:Agonist activity at human A2B receptor expressed in Flp-In-CHO cells assessed as cAMP accumulation incubated for 10 mins in presence of forskolin by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetAdenosine receptor A2b(Human)
Monash University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 21220BDBM21220(CHEMBL464859 | N-Ethylcarboxamidoadenosine | Adeno...)
Affinity DataEC50:  4.80nMAssay Description:Agonist activity at human A2B receptor expressed in Flp-In-CHO cells assessed as cAMP accumulation incubated for 10 mins in presence of forskolin by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetAdenosine receptor A2b(Human)
Monash University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50594312BDBM50594312(CHEMBL5203917)
Affinity DataEC50:  6.30nMAssay Description:Agonist activity at human A2B receptor expressed in Flp-In-CHO cells assessed as cAMP accumulation incubated for 10 mins in presence of forskolin by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetAdenosine receptor A2b(Human)
Monash University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50205591BDBM50205591(1-deoxy-1-[6-{4-[(phenylcarbamoyl)-methoxy]-phenyl...)
Affinity DataEC50:  7.30nMAssay Description:Agonist activity at human adenosine A2B receptor expressed in CHO cells assessed as stimulation of cAMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
Monash University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50150076BDBM50150076(2-Amino-6-(1H-imidazol-2-ylmethylsulfanyl)-4-(4-me...)
Affinity DataEC50:  9nMAssay Description:Agonistic activity against human adenosine A2B receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
Monash University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50458354BDBM50458354(CHEMBL4216880)
Affinity DataEC50:  9.5nMAssay Description:Agonist activity at human adenosine A2B receptor expressed in CHO cell membranes assessed as induction of cAMP accumulation by AlphaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
Monash University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 561407BDBM561407(US11390624, Example 22 | 3-(4-amino-2-(pyridin-2-y...)
Affinity DataEC50: <10nMAssay Description:Stably transfected HEK-293 cells expressing the human adenosine A2B receptor (Perkin Elmer) were maintained in MEM culture medium with 10% FBS and 10...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent

TargetAdenosine receptor A2b(Human)
Monash University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 524526BDBM524526(US11168089, Ex. No. 2 | US11873304, Example 2)
Affinity DataEC50: <10nMAssay Description:Assays are conducted in deep well polypropylene plates (Greiner 786201) in a final volume of 550 μL. Test compounds are first serially diluted i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2024
Entry Details
US Patent

TargetAdenosine receptor A2b(Human)
Monash University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 561406BDBM561406(US11390624, Example 21 | 3-(4-amino-7-(oxazol-5-yl...)
Affinity DataEC50: <10nMAssay Description:Stably transfected HEK-293 cells expressing the human adenosine A2B receptor (Perkin Elmer) were maintained in MEM culture medium with 10% FBS and 10...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent

TargetAdenosine receptor A2b(Human)
Monash University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 524527BDBM524527(US11168089, Ex. No. 3 | US11873304, Example 3)
Affinity DataEC50: <10nMAssay Description:Assays are conducted in deep well polypropylene plates (Greiner 786201) in a final volume of 550 μL. Test compounds are first serially diluted i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2024
Entry Details
US Patent

TargetAdenosine receptor A2b(Human)
Monash University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 561409BDBM561409(US11390624, Example 24 | 3-(4-amino-2-((6-methylpy...)
Affinity DataEC50: <10nMAssay Description:Stably transfected HEK-293 cells expressing the human adenosine A2B receptor (Perkin Elmer) were maintained in MEM culture medium with 10% FBS and 10...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent

TargetAdenosine receptor A2b(Human)
Monash University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 524525BDBM524525(US11168089, Ex. No. 1 | US11873304, Example 1 | US...)
Affinity DataEC50: <10nMAssay Description:Assays are conducted in deep well polypropylene plates (Greiner 786201) in a final volume of 550 μL. Test compounds are first serially diluted i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2024
Entry Details
US Patent

TargetAdenosine receptor A2b(Human)
Monash University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 524557BDBM524557(US11168089, Ex. No. 33 | US11873304, Example 33)
Affinity DataEC50: <10nMAssay Description:Assays are conducted in deep well polypropylene plates (Greiner 786201) in a final volume of 550 μL. Test compounds are first serially diluted i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2024
Entry Details
US Patent

TargetAdenosine receptor A2b(Human)
Monash University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 561411BDBM561411(US11390624, Example 26 | 3-(4-amino-2-((6-methylpy...)
Affinity DataEC50: <10nMAssay Description:Stably transfected HEK-293 cells expressing the human adenosine A2B receptor (Perkin Elmer) were maintained in MEM culture medium with 10% FBS and 10...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent

TargetAdenosine receptor A2b(Human)
Monash University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 561410BDBM561410(US11390624, Example 25 | 3-(4-amino-2-((6-methylpy...)
Affinity DataEC50: <10nMAssay Description:Stably transfected HEK-293 cells expressing the human adenosine A2B receptor (Perkin Elmer) were maintained in MEM culture medium with 10% FBS and 10...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent

TargetAdenosine receptor A2b(Human)
Monash University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 561413BDBM561413(US11390624, Example 28 | 3-(4-amino-7-(1-ethyl-1H-...)
Affinity DataEC50: <10nMAssay Description:Stably transfected HEK-293 cells expressing the human adenosine A2B receptor (Perkin Elmer) were maintained in MEM culture medium with 10% FBS and 10...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent

TargetAdenosine receptor A2b(Human)
Monash University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 561432BDBM561432(US11390624, Example 46 | 3-(4-amino-7-(4-methyloxa...)
Affinity DataEC50: <10nMAssay Description:Stably transfected HEK-293 cells expressing the human adenosine A2B receptor (Perkin Elmer) were maintained in MEM culture medium with 10% FBS and 10...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent

TargetAdenosine receptor A2b(Human)
Monash University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 524550BDBM524550(US11168089, Ex. No. 26 | US11873304, Example 26)
Affinity DataEC50: <10nMAssay Description:Assays are conducted in deep well polypropylene plates (Greiner 786201) in a final volume of 550 μL. Test compounds are first serially diluted i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2024
Entry Details
US Patent

TargetAdenosine receptor A2b(Human)
Monash University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 561431BDBM561431(US11390624, Example 45 | 3-(4-amino-2-((1-methyl-1...)
Affinity DataEC50: <10nMAssay Description:Stably transfected HEK-293 cells expressing the human adenosine A2B receptor (Perkin Elmer) were maintained in MEM culture medium with 10% FBS and 10...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent

TargetAdenosine receptor A2b(Human)
Monash University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 561401BDBM561401(US11390624, Example 16 | 3-(4-amino-2-(pyridin-2-y...)
Affinity DataEC50: <10nMAssay Description:Stably transfected HEK-293 cells expressing the human adenosine A2B receptor (Perkin Elmer) were maintained in MEM culture medium with 10% FBS and 10...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent

TargetAdenosine receptor A2b(Human)
Monash University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 561400BDBM561400(US11390624, Example 14 | 3-(7-amino-4-(1-ethyl-1H-...)
Affinity DataEC50: <10nMAssay Description:Stably transfected HEK-293 cells expressing the human adenosine A2B receptor (Perkin Elmer) were maintained in MEM culture medium with 10% FBS and 10...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent

TargetAdenosine receptor A2b(Human)
Monash University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 561403BDBM561403(US11390624, Example 18 | 3-(4-amino-7-(1-ethyl-1H-...)
Affinity DataEC50: <10nMAssay Description:Stably transfected HEK-293 cells expressing the human adenosine A2B receptor (Perkin Elmer) were maintained in MEM culture medium with 10% FBS and 10...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent

TargetAdenosine receptor A2b(Human)
Monash University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 524554BDBM524554(US11168089, Ex. No. 30 | US11873304, Example 30)
Affinity DataEC50: <10nMAssay Description:Assays are conducted in deep well polypropylene plates (Greiner 786201) in a final volume of 550 μL. Test compounds are first serially diluted i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2024
Entry Details
US Patent

TargetAdenosine receptor A2b(Human)
Monash University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 561402BDBM561402(US11390624, Example 17 | 3-(4-amino-7-(4-methyloxa...)
Affinity DataEC50: <10nMAssay Description:Stably transfected HEK-293 cells expressing the human adenosine A2B receptor (Perkin Elmer) were maintained in MEM culture medium with 10% FBS and 10...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent

TargetAdenosine receptor A2b(Human)
Monash University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 524555BDBM524555(US11168089, Ex. No. 31 | US11873304, Example 31)
Affinity DataEC50: <10nMAssay Description:Assays are conducted in deep well polypropylene plates (Greiner 786201) in a final volume of 550 μL. Test compounds are first serially diluted i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2024
Entry Details
US Patent

TargetAdenosine receptor A2b(Human)
Monash University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 561405BDBM561405(US11390624, Example 20 | 3-(4-amino-7-(4-(hydroxym...)
Affinity DataEC50: <10nMAssay Description:Stably transfected HEK-293 cells expressing the human adenosine A2B receptor (Perkin Elmer) were maintained in MEM culture medium with 10% FBS and 10...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent

TargetAdenosine receptor A2b(Human)
Monash University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 561404BDBM561404(US11390624, Example 19 | 3-(4-amino-7-(3-methylpyr...)
Affinity DataEC50: <10nMAssay Description:Stably transfected HEK-293 cells expressing the human adenosine A2B receptor (Perkin Elmer) were maintained in MEM culture medium with 10% FBS and 10...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent

TargetAdenosine receptor A2b(Human)
Monash University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 561423BDBM561423(US11390624, Example 38 | 3-(4-amino-7-(1-ethyl-1H-...)
Affinity DataEC50: <10nMAssay Description:Stably transfected HEK-293 cells expressing the human adenosine A2B receptor (Perkin Elmer) were maintained in MEM culture medium with 10% FBS and 10...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent

TargetAdenosine receptor A2b(Human)
Monash University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 524542BDBM524542(US11168089, Ex. No. 18 | US11873304, Example 18)
Affinity DataEC50: <10nMAssay Description:Assays are conducted in deep well polypropylene plates (Greiner 786201) in a final volume of 550 μL. Test compounds are first serially diluted i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2024
Entry Details
US Patent

TargetAdenosine receptor A2b(Human)
Monash University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 561393BDBM561393(US11390624, Example 7 | 3-(4-amino-2-(2-fluorobenz...)
Affinity DataEC50: <10nMAssay Description:Stably transfected HEK-293 cells expressing the human adenosine A2B receptor (Perkin Elmer) were maintained in MEM culture medium with 10% FBS and 10...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent

TargetAdenosine receptor A2b(Human)
Monash University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 561426BDBM561426(US11390624, Example 40 | 3-(4-amino-7-(1-isopropyl...)
Affinity DataEC50: <10nMAssay Description:Stably transfected HEK-293 cells expressing the human adenosine A2B receptor (Perkin Elmer) were maintained in MEM culture medium with 10% FBS and 10...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent

TargetAdenosine receptor A2b(Human)
Monash University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 561392BDBM561392(US11390624, Example 6 | 3-(4-amino-2-(pyridin-2-yl...)
Affinity DataEC50: <10nMAssay Description:Stably transfected HEK-293 cells expressing the human adenosine A2B receptor (Perkin Elmer) were maintained in MEM culture medium with 10% FBS and 10...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent

TargetAdenosine receptor A2b(Human)
Monash University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 561425BDBM561425(US11390624, Example 39 | 3-(4-amino-7-(1-methyl-1H...)
Affinity DataEC50: <10nMAssay Description:Stably transfected HEK-293 cells expressing the human adenosine A2B receptor (Perkin Elmer) were maintained in MEM culture medium with 10% FBS and 10...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent

TargetAdenosine receptor A2b(Human)
Monash University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50150078BDBM50150078(2-Amino-4-(3-hydroxy-phenyl)-6-(1H-imidazol-2-ylme...)
Affinity DataEC50:  10nMAssay Description:Agonistic activity against human adenosine A2B receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
Monash University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 561395BDBM561395(US11390624, Example 9 | 3-(7-amino-4-(1-ethyl-1H-p...)
Affinity DataEC50: <10nMAssay Description:Stably transfected HEK-293 cells expressing the human adenosine A2B receptor (Perkin Elmer) were maintained in MEM culture medium with 10% FBS and 10...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent

TargetAdenosine receptor A2b(Human)
Monash University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 524546BDBM524546(US11168089, Ex. No. 22 | US11873304, Example 22)
Affinity DataEC50: <10nMAssay Description:Assays are conducted in deep well polypropylene plates (Greiner 786201) in a final volume of 550 μL. Test compounds are first serially diluted i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2024
Entry Details
US Patent

TargetAdenosine receptor A2b(Human)
Monash University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 561394BDBM561394(US11390624, Example 8 | 3-(7-amino-2-(pyridin-2-yl...)
Affinity DataEC50: <10nMAssay Description:Stably transfected HEK-293 cells expressing the human adenosine A2B receptor (Perkin Elmer) were maintained in MEM culture medium with 10% FBS and 10...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent

TargetAdenosine receptor A2b(Human)
Monash University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 561427BDBM561427(US11390624, Example 41 | 3-(4-amino-7-(4-methyloxa...)
Affinity DataEC50: <10nMAssay Description:Stably transfected HEK-293 cells expressing the human adenosine A2B receptor (Perkin Elmer) were maintained in MEM culture medium with 10% FBS and 10...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent

TargetAdenosine receptor A2b(Human)
Monash University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 561430BDBM561430(US11390624, Example 44 | 3-(4-amino-2-((1-methyl-1...)
Affinity DataEC50: <10nMAssay Description:Stably transfected HEK-293 cells expressing the human adenosine A2B receptor (Perkin Elmer) were maintained in MEM culture medium with 10% FBS and 10...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent

TargetAdenosine receptor A2b(Human)
Monash University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 524544BDBM524544(US11168089, Ex. No. 20 | US11873304, Example 20)
Affinity DataEC50: <10nMAssay Description:Assays are conducted in deep well polypropylene plates (Greiner 786201) in a final volume of 550 μL. Test compounds are first serially diluted i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2024
Entry Details
US Patent

TargetAdenosine receptor A2b(Human)
Monash University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 561396BDBM561396(US11390624, Example 10 | 3-(7-amino-2-((6-methylpy...)
Affinity DataEC50: <10nMAssay Description:Stably transfected HEK-293 cells expressing the human adenosine A2B receptor (Perkin Elmer) were maintained in MEM culture medium with 10% FBS and 10...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent

TargetAdenosine receptor A2b(Human)
Monash University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 524545BDBM524545(US11168089, Ex. No. 21 | US11873304, Example 21)
Affinity DataEC50: <10nMAssay Description:Assays are conducted in deep well polypropylene plates (Greiner 786201) in a final volume of 550 μL. Test compounds are first serially diluted i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2024
Entry Details
US Patent

TargetAdenosine receptor A2b(Human)
Monash University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 561415BDBM561415(US11390624, Example 30 | 3-(4-amino-2-((3-fluoropy...)
Affinity DataEC50: <10nMAssay Description:Stably transfected HEK-293 cells expressing the human adenosine A2B receptor (Perkin Elmer) were maintained in MEM culture medium with 10% FBS and 10...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent

TargetAdenosine receptor A2b(Human)
Monash University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 561414BDBM561414(US11390624, Example 29 | 3-(4-amino-7-(4-methyloxa...)
Affinity DataEC50: <10nMAssay Description:Stably transfected HEK-293 cells expressing the human adenosine A2B receptor (Perkin Elmer) were maintained in MEM culture medium with 10% FBS and 10...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
US Patent

TargetAdenosine receptor A2b(Human)
Monash University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50263201BDBM50263201(CHEMBL4104819)
Affinity DataEC50:  10nMAssay Description:Agonist activity at A2BR in human NHVCF cells assessed as cAMP accumulation incubated for 30 mins by LANCE cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
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