Compile Data Set for Download or QSAR
Report error Found 17 of ec50 for UniProtKB: P22909
LigandPNGBDBM50027031((2-Chloro-phenyl)-(4,5-dihydro-1H-imidazol-2-ylmet...)
Affinity DataEC50:  53nMAssay Description:Agonistic activity against alpha-2 adrenergic receptor in isolated, field -simulated vas deferens from ratsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed
LigandPNGBDBM50027035(3-[(4,5-Dihydro-1H-imidazol-2-ylmethyl)-amino]-phe...)
Affinity DataEC50:  74nMAssay Description:Agonistic activity against alpha alpha-2 adrenergic receptor in isolated, field -simulated vas deferens from ratsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed
LigandPNGBDBM50470860(CHEMBL105328)
Affinity DataEC50:  156nMAssay Description:50% Molar effective concentration for agonistic activity against Alpha-1 adrenergic receptor in rat aortaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
LigandPNGBDBM31046(SMR000059054 | cid_91430 | 3-[4,5-dihydro-1H-imida...)
Affinity DataEC50: >1.00E+3nMAssay Description:Agonistic activity against alpha alpha-2 adrenergic receptor in isolated, field -simulated vas deferens from ratsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed
LigandPNGBDBM50027036((4,5-Dihydro-1H-imidazol-2-ylmethyl)-methyl-p-toly...)
Affinity DataEC50: >2.00E+3nMAssay Description:Agonistic activity against alpha alpha-2 adrenergic receptor in isolated, field -simulated vas deferens from ratsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed
LigandPNGBDBM50027032((4,5-Dihydro-1H-imidazol-2-ylmethyl)-p-tolyl-amine...)
Affinity DataEC50: >2.00E+3nMAssay Description:Agonistic activity against alpha alpha-2 adrenergic receptor in isolated, field -simulated vas deferens from ratsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed
LigandPNGBDBM50019061(CHEMBL281232 | 4-(2-Amino-1-hydroxy-ethyl)-5-fluor...)
Affinity DataEC50:  3.00E+3nMAssay Description:Displacement of [3H]WB4101 from alpha-adrenergic receptor in Sprague-Dawley rat cerebral cortical membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
LigandPNGBDBM35234(Noradrenaline,(+) | NOREPINEPHRINE | DL-[7-3H]nore...)
Affinity DataEC50:  3.00E+3nMAssay Description:Displacement of [3H]WB4101 from alpha-adrenergic receptor in Sprague-Dawley rat cerebral cortical membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
LigandPNGBDBM35234(Noradrenaline,(+) | NOREPINEPHRINE | DL-[7-3H]nore...)
Affinity DataEC50:  5.00E+3nMAssay Description:Agonist activity at alpha-adrenergic receptor in Sprague-Dawley rat cerebral cortex assessed as [3H]cAMP accumulation by liquid scintillation spectro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
LigandPNGBDBM50019061(CHEMBL281232 | 4-(2-Amino-1-hydroxy-ethyl)-5-fluor...)
Affinity DataEC50:  5.00E+3nMAssay Description:Agonist activity at alpha-adrenergic receptor in Sprague-Dawley rat cerebral cortex assessed as [3H]cAMP accumulation by liquid scintillation spectro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
LigandPNGBDBM50042998(5-(2-Amino-1-hydroxy-ethyl)-3-fluoro-benzene-1,2-d...)
Affinity DataEC50:  5.00E+3nMAssay Description:Agonist activity at alpha-adrenergic receptor in Sprague-Dawley rat cerebral cortex assessed as [3H]cAMP accumulation by liquid scintillation spectro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
LigandPNGBDBM50027034((4,5-Dihydro-1H-imidazol-2-ylmethyl)-phenyl-p-toly...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonistic activity against alpha alpha-2 adrenergic receptor in isolated, field -simulated vas deferens from ratsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed
LigandPNGBDBM50027037((4,5-Dihydro-1H-imidazol-2-ylmethyl)-ethyl-p-tolyl...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonistic activity against alpha alpha-2 adrenergic receptor in isolated, field -simulated vas deferens from ratsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed
LigandPNGBDBM50027033(Cyclohexyl-(4,5-dihydro-1H-imidazol-2-ylmethyl)-p-...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonistic activity against alpha alpha-2 adrenergic receptor in isolated, field -simulated vas deferens from ratsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed
LigandPNGBDBM50042998(5-(2-Amino-1-hydroxy-ethyl)-3-fluoro-benzene-1,2-d...)
Affinity DataEC50:  1.50E+4nMAssay Description:Displacement of [3H]WB4101 from alpha-adrenergic receptor in Sprague-Dawley rat cerebral cortical membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
LigandPNGBDBM50019060(CHEMBL287587 | 4-(2-Amino-1-hydroxy-ethyl)-3-fluor...)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at alpha-adrenergic receptor in Sprague-Dawley rat cerebral cortex assessed as [3H]cAMP accumulation by liquid scintillation spectro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
LigandPNGBDBM50019060(CHEMBL287587 | 4-(2-Amino-1-hydroxy-ethyl)-3-fluor...)
Affinity DataEC50: >1.00E+5nMAssay Description:Displacement of [3H]WB4101 from alpha-adrenergic receptor in Sprague-Dawley rat cerebral cortical membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed