Compile Data Set for Download or QSAR
maximum 50k data
Found 27 of ic50 for UniProtKB: A0A0S2Z4R1
TargetTyrosine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM18128((2S)-2-[(2S)-2-amino-3-(4-hydroxyphenyl)propanamid...)
Affinity DataIC50:  0.600nMAssay Description:Inhibitory activity against Bacterial Tyrosyl tRNA SynthetaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50097749(CHEMBL163375 | [2-Amino-3-((S)-4-hydroxy-phenyl)-p...)
Affinity DataIC50:  0.800nMAssay Description:Inhibitory activity against Staphylococcus aureus tyrosyl tRNA synthetase (YRS) using aminoacylation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50091497((S)-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylami...)
Affinity DataIC50:  1.20nMAssay Description:Inhibitory activity of compound against tyrosyl tRNA synthetase from Staphylococcus aureus was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50091497((S)-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylami...)
Affinity DataIC50:  1.20nMAssay Description:Inhibitory activity against Staphylococcus aureus tyrosyl tRNA synthetase (YRS) using aminoacylation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM18128((2S)-2-[(2S)-2-amino-3-(4-hydroxyphenyl)propanamid...)
Affinity DataIC50:  1.40nMAssay Description:Inhibitory activity of compound against tyrosyl tRNA synthetase from Staphylococcus aureus was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50097746((S)-[2-Amino-3-((S)-4-hydroxy-phenyl)-propionylami...)
Affinity DataIC50:  2nMAssay Description:Inhibitory activity against Staphylococcus aureus tyrosyl tRNA synthetase (YRS) using aminoacylation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50104311((S)-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylami...)
Affinity DataIC50:  3.40nMAssay Description:Inhibitory activity against Bacterial Tyrosyl tRNA SynthetaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50097748(CHEMBL351127 | [2-Amino-3-((S)-4-hydroxy-phenyl)-p...)
Affinity DataIC50:  3.60nMAssay Description:Inhibitory activity against Staphylococcus aureus tyrosyl tRNA synthetase (YRS) using aminoacylation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM18132((2S)-2-[(2S)-2-amino-3-(4-hydroxyphenyl)propanamid...)
Affinity DataIC50:  4nMAssay Description:Inhibitory activity against Staphylococcus aureus tyrosyl tRNA synthetase (YRS) using aminoacylation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50091496((R)-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylami...)
Affinity DataIC50:  21nMAssay Description:Inhibitory activity of compound against tyrosyl tRNA synthetase from Staphylococcus aureus was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50097744((S)-[2-Amino-3-((S)-4-hydroxy-phenyl)-propionylami...)
Affinity DataIC50:  100nMAssay Description:Inhibitory activity against Staphylococcus aureus tyrosyl tRNA synthetase (YRS) using aminoacylation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50097744((S)-[2-Amino-3-((S)-4-hydroxy-phenyl)-propionylami...)
Affinity DataIC50:  100nMAssay Description:Inhibitory activity against Staphylococcus aureus tyrosyl tRNA synthetase (YRS) using aminoacylation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50104310((R)-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylami...)
Affinity DataIC50:  124nMAssay Description:Inhibitory activity against Bacterial Tyrosyl tRNA SynthetaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50097747(CHEMBL162552 | [2-Amino-3-((S)-4-hydroxy-phenyl)-p...)
Affinity DataIC50:  190nMAssay Description:Inhibitory activity against Staphylococcus aureus tyrosyl tRNA synthetase (YRS) using aminoacylation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50104313((S)-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylami...)
Affinity DataIC50:  245nMAssay Description:Inhibitory activity against Bacterial Tyrosyl tRNA SynthetaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50097745(CHEMBL159436 | [2-Amino-3-((S)-4-hydroxy-phenyl)-p...)
Affinity DataIC50:  260nMAssay Description:Inhibitory activity against Staphylococcus aureus tyrosyl tRNA synthetase (YRS) using aminoacylation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50081838(CHEMBL318019 | [(S)-2-Amino-3-(4-hydroxy-phenyl)-p...)
Affinity DataIC50:  510nMAssay Description:Compound was tested for inhibition of Staphylococcus aureus tyrosyl tRNA SynthetaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50081839(CHEMBL98455 | [(S)-2-Amino-3-(4-hydroxy-phenyl)-pr...)
Affinity DataIC50:  800nMAssay Description:Compound was tested for inhibition of Staphylococcus aureus tyrosyl tRNA SynthetaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50081834((S)-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylami...)
Affinity DataIC50:  900nMAssay Description:Compound was tested for inhibition of Staphylococcus aureus tyrosyl tRNA SynthetaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50081837(CHEMBL99347 | [(S)-2-Amino-3-(4-hydroxy-phenyl)-pr...)
Affinity DataIC50:  1.20E+3nMAssay Description:Compound was tested for inhibition of Staphylococcus aureus tyrosyl tRNA SynthetaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50104314((S)-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylami...)
Affinity DataIC50: >3.00E+3nMAssay Description:Inhibitory activity against Bacterial Tyrosyl tRNA SynthetaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50104312((R)-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylami...)
Affinity DataIC50: >3.00E+3nMAssay Description:Inhibitory activity against Bacterial Tyrosyl tRNA SynthetaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50081841(CHEMBL95581 | [(S)-2-Amino-3-(4-hydroxy-phenyl)-pr...)
Affinity DataIC50:  3.40E+3nMAssay Description:Compound was tested for inhibition of Staphylococcus aureus tyrosyl tRNA SynthetaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50081840((S)-2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyla...)
Affinity DataIC50:  3.80E+3nMAssay Description:Compound was tested for inhibition of Staphylococcus aureus tyrosyl tRNA SynthetaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50081836(CHEMBL95616 | [(S)-2-Amino-3-(4-hydroxy-phenyl)-pr...)
Affinity DataIC50:  7.80E+3nMAssay Description:Compound was tested for inhibition of Staphylococcus aureus tyrosyl tRNA SynthetaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50081835((S)-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylami...)
Affinity DataIC50:  1.10E+4nMAssay Description:Compound was tested for inhibition of Staphylococcus aureus tyrosyl tRNA SynthetaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM18128((2S)-2-[(2S)-2-amino-3-(4-hydroxyphenyl)propanamid...)
Affinity DataIC50:  2.20E+4nMAssay Description:Inhibitory activity of compound against tyrosyl tRNA synthetase from mammalian cells was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed