Compile Data Set for Download or QSAR
maximum 50k data
Found 55 of ic50 data for polymerid = 50001907
TargetAldo-keto reductase family 1 member A1(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50009832(1-Benzyl-4-hydroxy-5-oxo-2,5-dihydro-1H-pyrrole-3-...)
Affinity DataIC50:  28nMAssay Description:Inhibitory activity was measured against renal inner medulla aldehyde reductaseChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member A1(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM16312((4S)-6-fluoro-2,3-dihydrospiro[1-benzopyran-4,4'-i...)
Affinity DataIC50:  29nMAssay Description:In vitro inhibitory activity against aldehyde reductase 1 (ALR1) from rat kidney.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member A1(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50330615(4-Amino-N-(4-bromo-2-fluorobenzyl)-N-(3,5-difluoro...)
Affinity DataIC50:  323nMAssay Description:Inhibition of Fischer-344 rat kidney AK1A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member A1(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50126777(CHEMBL33835 | Cyano-[5-fluoro-1-(4-fluoro-benzyl)-...)
Affinity DataIC50:  490nMAssay Description:In vitro inhibitory activity against aldehyde reductase 1 (ALR1) from rat kidney.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member A1(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50126780(CHEMBL30993 | Cyano-[5-fluoro-1-(4-methyl-benzyl)-...)
Affinity DataIC50:  690nMAssay Description:In vitro inhibitory activity against aldehyde reductase 1 (ALR1) from rat kidney.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member A1(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM16314(2-{[6-methoxy-5-(trifluoromethyl)naphthalen-1-yl]-...)
Affinity DataIC50:  1.21E+3nMAssay Description:Evaluated for inhibition of Aldehyde reductase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member A1(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50049730(2-(5-(2-methyl-3-phenylallylidene)-4-oxo-2-thioxot...)
Affinity DataIC50:  1.50E+3nMAssay Description:In vitro inhibitory activity against rat kidney aldehyde reductase(ALR).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member A1(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM16312((4S)-6-fluoro-2,3-dihydrospiro[1-benzopyran-4,4'-i...)
Affinity DataIC50:  1.74E+3nMAssay Description:Evaluated for inhibition of Aldehyde reductase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member A1(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM7460(2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-4H-chrome...)
Affinity DataIC50:  2.32E+3nMAssay Description:In vitro inhibitory activity against aldehyde reductase 1 (ALR1) from rat kidney.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member A1(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50126791(CHEMBL281442 | Cyano-[1-(4-methyl-benzyl)-2-oxo-2,...)
Affinity DataIC50:  3.57E+3nMAssay Description:In vitro inhibitory activity against aldehyde reductase 1 (ALR1) from rat kidney.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member A1(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50126774(CHEMBL284593 | Cyano-(5-fluoro-2-oxo-2,3-dihydro-1...)
Affinity DataIC50:  6.79E+3nMAssay Description:In vitro inhibitory activity against aldehyde reductase 1 (ALR1) from rat kidney.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member A1(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50330610(CHEMBL1277203 | N-(4-(N-(3,5-Difluoro-4-hydroxyphe...)
Affinity DataIC50:  6.90E+3nMAssay Description:Inhibition of Fischer-344 rat kidney AK1A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member A1(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50330616(CHEMBL1277477 | N-(3,5-Difluoro-4-hydroxyphenyl)-N...)
Affinity DataIC50:  9.70E+3nMAssay Description:Inhibition of Fischer-344 rat kidney AK1A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member A1(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50251025(4-Amino-N-(3,5-difluoro-4-hydroxyphenyl)benzenesul...)
Affinity DataIC50:  1.03E+4nMAssay Description:Inhibition of Fischer-344 rat kidney AK1A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member A1(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50330613(CHEMBL1277386 | N-(4-Bromo-2-fluorobenzyl)-N-(3,5-...)
Affinity DataIC50:  1.19E+4nMAssay Description:Inhibition of Fischer-344 rat kidney AK1A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member A1(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50330611(CHEMBL1277297 | N-(4-(N-(3,5-Difluoro-4-hydroxyphe...)
Affinity DataIC50:  1.24E+4nMAssay Description:Inhibition of Fischer-344 rat kidney AK1A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member A1(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50009832(1-Benzyl-4-hydroxy-5-oxo-2,5-dihydro-1H-pyrrole-3-...)
Affinity DataIC50:  1.40E+4nMAssay Description:Inhibitory activity was measured against whole kidney aldehyde reductaseChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member A1(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50330614(CHEMBL1277387 | N-(4-Bromo-2-fluorobenzyl)-N-(3,5-...)
Affinity DataIC50:  1.54E+4nMAssay Description:Inhibition of Fischer-344 rat kidney AK1A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member A1(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50251023(CHEMBL458568 | N-(3,5-Difluoro-4-hydroxyphenyl)ben...)
Affinity DataIC50:  1.96E+4nMAssay Description:Inhibition of Fischer-344 rat kidney AK1A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member A1(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50251030(CHEMBL458588 | N-(3,5-Difluoro-4-hydroxyphenyl)-4-...)
Affinity DataIC50:  2.38E+4nMAssay Description:Inhibition of Fischer-344 rat kidney AK1A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member A1(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50330612(CHEMBL1277298 | N-(3,5-Difluoro-4-hydroxyphenyl)-4...)
Affinity DataIC50:  2.55E+4nMAssay Description:Inhibition of Fischer-344 rat kidney AK1A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member A1(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50056532(CHEMBL434076 | [3-(3-Nitro-benzyl)-4,5-dioxo-2-thi...)
Affinity DataIC50:  2.80E+4nMAssay Description:In vitro inhibitory activity against rat kidney aldehyde reductase(ALR).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member A1(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50009832(1-Benzyl-4-hydroxy-5-oxo-2,5-dihydro-1H-pyrrole-3-...)
Affinity DataIC50:  3.54E+4nMAssay Description:Inhibitory activity was measured against rat lens aldose reductase in the presence of 1 uM compound with DL-glyceraldehyde as substratesChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member A1(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50003616(2-n-propyl-n-valeric acid | CHEMBL109 | DPA | Di-n...)
Affinity DataIC50:  5.01E+4nMAssay Description:Inhibition of rat kidney aldehyde reductase at 0.1 mM after 20 mins by spectrometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member A1(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50003616(2-n-propyl-n-valeric acid | CHEMBL109 | DPA | Di-n...)
Affinity DataIC50:  5.61E+4nMAssay Description:Inhibition of Fischer-344 rat kidney AK1A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member A1(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50056540(CHEMBL159413 | [3-(5-Chloro-benzothiazol-2-ylmethy...)
Affinity DataIC50:  5.80E+4nMAssay Description:In vitro inhibitory activity against rat kidney aldehyde reductase(ALR).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member A1(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50056525(CHEMBL433898 | [4-Methylene-3-(3-nitro-benzyl)-2,5...)
Affinity DataIC50:  5.80E+4nMAssay Description:In vitro inhibitory activity against rat kidney aldehyde reductase(ALR).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member A1(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50056531(CHEMBL161043 | [3-(4-Chloro-benzothiazol-2-ylmethy...)
Affinity DataIC50:  7.20E+4nMAssay Description:In vitro inhibitory activity against rat kidney aldehyde reductase(ALR).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member A1(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50054328(4-(3-Oxo-5,6-dihydro-3H-benzo[h]cinnolin-2-yl)-but...)
Affinity DataIC50:  9.26E+4nMAssay Description:Evaluated for inhibition of Aldehyde reductase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member A1(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50056529(CHEMBL159877 | [3-(3-Nitro-benzyl)-2,4-dioxo-imida...)
Affinity DataIC50: >1.00E+5nMAssay Description:In vitro inhibitory activity against rat kidney aldehyde reductase(ALR).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member A1(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50056530(CHEMBL161235 | [3-(3-Nitro-benzyl)-2,6-dioxo-3,6-d...)
Affinity DataIC50: >1.00E+5nMAssay Description:In vitro inhibitory activity against rat kidney aldehyde reductase(ALR).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member A1(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50056527(CHEMBL161556 | [3-(4-Chloro-3-nitro-benzyl)-2,4-di...)
Affinity DataIC50: >1.00E+5nMAssay Description:In vitro inhibitory activity against rat kidney aldehyde reductase(ALR).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member A1(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50049729(CHEMBL292887 | [3-(3-Nitro-benzyl)-2,4,5-trioxo-im...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory activity against rat kidney aldehyde reductase (ALR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member A1(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50056533(CHEMBL349508 | [3-(4-Chloro-3-nitro-benzyl)-2,4-di...)
Affinity DataIC50: >1.00E+5nMAssay Description:In vitro inhibitory activity against rat kidney aldehyde reductase(ALR).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member A1(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50056534(CHEMBL162697 | [3-(4-Chloro-benzothiazol-2-ylmethy...)
Affinity DataIC50: >1.00E+5nMAssay Description:In vitro inhibitory activity against rat kidney aldehyde reductase(ALR).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member A1(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50056528(CHEMBL160151 | CHEMBL351564 | [4-Hydroxy-3-(3-nitr...)
Affinity DataIC50: >1.00E+5nMAssay Description:In vitro inhibitory activity against rat kidney aldehyde reductase(ALR).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member A1(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50056535(CHEMBL355148 | [3-(4-Chloro-3-nitro-benzyl)-2,4,5-...)
Affinity DataIC50: >1.00E+5nMAssay Description:In vitro inhibitory activity against rat kidney aldehyde reductase(ALR).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member A1(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50056539(CHEMBL159384 | [3-(4-Chloro-benzothiazol-2-ylmethy...)
Affinity DataIC50: >1.00E+5nMAssay Description:In vitro inhibitory activity against rat kidney aldehyde reductase(ALR).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member A1(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50056538(CHEMBL159820 | [3-(5-Chloro-benzothiazol-2-ylmethy...)
Affinity DataIC50: >1.00E+5nMAssay Description:In vitro inhibitory activity against rat kidney aldehyde reductase(ALR).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member A1(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50056541(CHEMBL159288 | [2-Methylene-3-(3-nitro-benzyl)-4,5...)
Affinity DataIC50: >1.00E+5nMAssay Description:In vitro inhibitory activity against rat kidney aldehyde reductase(ALR).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member A1(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50056537(CHEMBL159475 | [3-(3-Nitro-benzyl)-2,4,6-trioxo-te...)
Affinity DataIC50: >1.00E+5nMAssay Description:In vitro inhibitory activity against rat kidney aldehyde reductase(ALR).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member A1(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50056526(CHEMBL160032 | [3-(3-Nitro-benzyl)-2,4-dioxo-3,4-d...)
Affinity DataIC50: >1.00E+5nMAssay Description:In vitro inhibitory activity against rat kidney aldehyde reductase(ALR).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member A1(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50056536(CHEMBL159750 | [3-(3-Nitro-benzyl)-2,5-dioxo-imida...)
Affinity DataIC50: >1.00E+5nMAssay Description:In vitro inhibitory activity against rat kidney aldehyde reductase(ALR).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member A1(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50056528(CHEMBL160151 | CHEMBL351564 | [4-Hydroxy-3-(3-nitr...)
Affinity DataIC50: >1.00E+5nMAssay Description:In vitro inhibitory activity against rat kidney aldehyde reductase(ALR).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member A1(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50330608(CHEMBL1277113 | N-(3,5-Difluoro-4-hydroxyphenyl)-4...)
Affinity DataIC50:  1.05E+5nMAssay Description:Inhibition of Fischer-344 rat kidney AK1A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member A1(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50054324((3-Oxo-3,5-dihydro-indeno[1,2-c]pyridazin-2-yl)-ac...)
Affinity DataIC50:  1.07E+5nMAssay Description:Evaluated for inhibition of Aldehyde reductase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member A1(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50251024(CHEMBL457486 | N-(3,5-Difluoro-4-hydroxyphenyl)-4-...)
Affinity DataIC50:  1.33E+5nMAssay Description:Inhibition of Fischer-344 rat kidney AK1A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member A1(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50054316(2-Carboxymethyl-3-oxo-3,5-dihydro-2H-indeno[1,2-c]...)
Affinity DataIC50:  1.36E+5nMAssay Description:Evaluated for inhibition of Aldehyde reductase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member A1(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50054320((3-Oxo-5,6-dihydro-3H-benzo[h]cinnolin-2-yl)-aceti...)
Affinity DataIC50:  1.56E+5nMAssay Description:Evaluated for inhibition of Aldehyde reductase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member A1(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50054329(2-Carboxymethyl-3-oxo-2,3,5,6-tetrahydro-benzo[h]c...)
Affinity DataIC50:  1.61E+5nMAssay Description:Evaluated for inhibition of Aldehyde reductase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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