Compile Data Set for Download or QSAR
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TargetTrifunctional purine biosynthetic protein adenosine-3(Mouse)
University of South Alabama

Curated by ChEMBL
LigandPNGBDBM50016658(CHEMBL279302 | 2-{4-[3-(2-Amino-4-oxo-3,4,5,6,7,8-...)
Affinity DataIC50: 0.0180nMAssay Description:Inhibition of the GAR formyl transferase in L1210More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTrifunctional purine biosynthetic protein adenosine-3(Mouse)
University of South Alabama

Curated by ChEMBL
LigandPNGBDBM50016660(CHEMBL23388 | 2-{4-[2-(2-Amino-4-oxo-3,4,5,6,7,8-h...)
Affinity DataIC50: 0.0200nMAssay Description:Inhibition of the GAR formyl transferase in L1210More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTrifunctional purine biosynthetic protein adenosine-3(Mouse)
University of South Alabama

Curated by ChEMBL
LigandPNGBDBM50022739((6RS) 2-{4-[2-(2-Amino-5-ethyl-4-oxo-3,4,5,6,7,8-h...)
Affinity DataIC50: 10nMAssay Description:Inhibition of GAR transformylase from Lactobacillus caseiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTrifunctional purine biosynthetic protein adenosine-3(Mouse)
University of South Alabama

Curated by ChEMBL
LigandPNGBDBM50306576((S)-2-({5-[4-(2-Amino-4-oxo-4,7-dihydro-3H-pyrrolo...)
Affinity DataIC50: 60nMAssay Description:Inhibition of mouse recombinant GARFtase assessed as FGAR formation by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetTrifunctional purine biosynthetic protein adenosine-3(Mouse)
University of South Alabama

Curated by ChEMBL
LigandPNGBDBM50281129((S)-2-{4-[2-(2-Amino-5,6,7,8-tetrahydro-pyrido[2,3...)
Affinity DataIC50: 65nMAssay Description:Tested for the inhibition against the human dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetTrifunctional purine biosynthetic protein adenosine-3(Mouse)
University of South Alabama

Curated by ChEMBL
LigandPNGBDBM50171511(N-{4-[4-(2-Amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-...)
Affinity DataIC50: 150nMAssay Description:Inhibition of mouse recombinant GARFTaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetTrifunctional purine biosynthetic protein adenosine-3(Mouse)
University of South Alabama

Curated by ChEMBL
LigandPNGBDBM50022739((6RS) 2-{4-[2-(2-Amino-5-ethyl-4-oxo-3,4,5,6,7,8-h...)
Affinity DataIC50: 500nMAssay Description:Inhibition of GAR transformylase from mammalian MancaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTrifunctional purine biosynthetic protein adenosine-3(Mouse)
University of South Alabama

Curated by ChEMBL
LigandPNGBDBM50022739((6RS) 2-{4-[2-(2-Amino-5-ethyl-4-oxo-3,4,5,6,7,8-h...)
Affinity DataIC50: 500nMAssay Description:Inhibition of GAR transformylase from mammalian L1210 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTrifunctional purine biosynthetic protein adenosine-3(Mouse)
University of South Alabama

Curated by ChEMBL
LigandPNGBDBM50022741((5RS, 6RS) 2-{4-[2-(2-Amino-5-methyl-4-oxo-3,4,5,6...)
Affinity DataIC50: 720nMAssay Description:Inhibition of GAR transformylase from Lactobacillus caseiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTrifunctional purine biosynthetic protein adenosine-3(Mouse)
University of South Alabama

Curated by ChEMBL
LigandPNGBDBM50005518(CHEMBL142806 | (S)-2-{(R)-4-[2-((R)-2-Amino-4-oxo-...)
Affinity DataIC50: 780nMAssay Description:Inhibition of mouse recombinant GARFtase assessed as FGAR formation by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetTrifunctional purine biosynthetic protein adenosine-3(Mouse)
University of South Alabama

Curated by ChEMBL
LigandPNGBDBM50005518(CHEMBL142806 | (S)-2-{(R)-4-[2-((R)-2-Amino-4-oxo-...)
Affinity DataIC50: 780nMAssay Description:Inhibition of mouse recombinant GARFTaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetTrifunctional purine biosynthetic protein adenosine-3(Mouse)
University of South Alabama

Curated by ChEMBL
LigandPNGBDBM22590(5,10-dideazatetrahydrofolic acid | DDF | (2S)-2-[(...)
Affinity DataIC50: 780nMAssay Description:Inhibition of mouse recombinant GARFTaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTrifunctional purine biosynthetic protein adenosine-3(Mouse)
University of South Alabama

Curated by ChEMBL
LigandPNGBDBM50272272(N-{4-[5-(2-Amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-...)
Affinity DataIC50: 2.26E+3nMAssay Description:Inhibition of mouse recombinant GARFTaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetTrifunctional purine biosynthetic protein adenosine-3(Mouse)
University of South Alabama

Curated by ChEMBL
LigandPNGBDBM50171513((S)-2-(4-(3-(2-amino-4-oxo-4,7-dihydro-3H-pyrrolo[...)
Affinity DataIC50: 2.44E+3nMAssay Description:Inhibition of mouse recombinant GARFTaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetTrifunctional purine biosynthetic protein adenosine-3(Mouse)
University of South Alabama

Curated by ChEMBL
LigandPNGBDBM50272273(N-{4-[6-(2-Amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-...)
Affinity DataIC50: 2.51E+3nMAssay Description:Inhibition of mouse recombinant GARFTaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetTrifunctional purine biosynthetic protein adenosine-3(Mouse)
University of South Alabama

Curated by ChEMBL
LigandPNGBDBM50306577((S)-2-({5-[5-(2-Amino-4-oxo-4,7-dihydro-3H-pyrrolo...)
Affinity DataIC50: 3.31E+3nMAssay Description:Inhibition of mouse recombinant GARFtase assessed as FGAR formation by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetTrifunctional purine biosynthetic protein adenosine-3(Mouse)
University of South Alabama

Curated by ChEMBL
LigandPNGBDBM50249877((S)-2-(4-(4-(2-amino-4-oxo-3,4-dihydrothieno[2,3-d...)
Affinity DataIC50: 5.51E+3nMAssay Description:Inhibition of mouse recombinant GARFTaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTrifunctional purine biosynthetic protein adenosine-3(Mouse)
University of South Alabama

Curated by ChEMBL
LigandPNGBDBM50249876(N-{4-[3-(2-Amino-4-oxo-3,4-dihydrothieno[2,3-d]pyr...)
Affinity DataIC50: 8.52E+3nMAssay Description:Inhibition of mouse recombinant GARFTaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTrifunctional purine biosynthetic protein adenosine-3(Mouse)
University of South Alabama

Curated by ChEMBL
LigandPNGBDBM50022741((5RS, 6RS) 2-{4-[2-(2-Amino-5-methyl-4-oxo-3,4,5,6...)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of GAR transformylase from mammalian MancaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTrifunctional purine biosynthetic protein adenosine-3(Mouse)
University of South Alabama

Curated by ChEMBL
LigandPNGBDBM18796((2S)-2-{[4-(2-{2-amino-4-oxo-1H,4H,7H-pyrrolo[2,3-...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of mouse recombinant GARFTaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetTrifunctional purine biosynthetic protein adenosine-3(Mouse)
University of South Alabama

Curated by ChEMBL
LigandPNGBDBM18050(MTX | cid_126941 | Methotrexate | 2-[(4-{[(2,4-dia...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of GAR transformylase from Lactobacillus caseiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTrifunctional purine biosynthetic protein adenosine-3(Mouse)
University of South Alabama

Curated by ChEMBL
LigandPNGBDBM50022740(2-{4-[2-(2-Amino-5-methyl-4-oxo-3,4-dihydro-pyrido...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of GAR transformylase from mammalian MancaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTrifunctional purine biosynthetic protein adenosine-3(Mouse)
University of South Alabama

Curated by ChEMBL
LigandPNGBDBM50272231((S)-2-(4-((2-amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of mouse recombinant GARFTaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetTrifunctional purine biosynthetic protein adenosine-3(Mouse)
University of South Alabama

Curated by ChEMBL
LigandPNGBDBM50022740(2-{4-[2-(2-Amino-5-methyl-4-oxo-3,4-dihydro-pyrido...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of GAR transformylase from Lactobacillus caseiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTrifunctional purine biosynthetic protein adenosine-3(Mouse)
University of South Alabama

Curated by ChEMBL
LigandPNGBDBM18796((2S)-2-{[4-(2-{2-amino-4-oxo-1H,4H,7H-pyrrolo[2,3-...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of mouse recombinant GARFtase assessed as FGAR formation by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetTrifunctional purine biosynthetic protein adenosine-3(Mouse)
University of South Alabama

Curated by ChEMBL
LigandPNGBDBM18796((2S)-2-{[4-(2-{2-amino-4-oxo-1H,4H,7H-pyrrolo[2,3-...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of mouse recombinant GARFTaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTrifunctional purine biosynthetic protein adenosine-3(Mouse)
University of South Alabama

Curated by ChEMBL
LigandPNGBDBM50249954(N-{4-[6-(2-Amino-4-oxo-3,4-dihydrothieno[2,3-d]pyr...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of mouse recombinant GARFTaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTrifunctional purine biosynthetic protein adenosine-3(Mouse)
University of South Alabama

Curated by ChEMBL
LigandPNGBDBM50249953(N-{4-[5-(2-Amino-4-oxo-3,4-dihydrothieno[2,3-d]pyr...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of mouse recombinant GARFTaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTrifunctional purine biosynthetic protein adenosine-3(Mouse)
University of South Alabama

Curated by ChEMBL
LigandPNGBDBM50249875(N-{4-[2-(2-Amino-4-oxo-3,4-dihydrothieno[2,3-d]pyr...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of mouse recombinant GARFTaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTrifunctional purine biosynthetic protein adenosine-3(Mouse)
University of South Alabama

Curated by ChEMBL
LigandPNGBDBM18050(MTX | cid_126941 | Methotrexate | 2-[(4-{[(2,4-dia...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of GAR transformylase from mammalian L1210 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTrifunctional purine biosynthetic protein adenosine-3(Mouse)
University of South Alabama

Curated by ChEMBL
LigandPNGBDBM50022740(2-{4-[2-(2-Amino-5-methyl-4-oxo-3,4-dihydro-pyrido...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of GAR transformylase from mammalian L1210 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTrifunctional purine biosynthetic protein adenosine-3(Mouse)
University of South Alabama

Curated by ChEMBL
LigandPNGBDBM50016657(CHEMBL284013 | 2-{4-[3-(2-Amino-4-oxo-3,4-dihydro-...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of the GAR formyl transferase in L1210More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTrifunctional purine biosynthetic protein adenosine-3(Mouse)
University of South Alabama

Curated by ChEMBL
LigandPNGBDBM50003059(CHEMBL123231 | 2-[4-(7-Amino-9-oxo-1,3,3a,4,5,8,9,...)
Affinity DataIC50: 4.00E+4nMAssay Description:Compound was evaluated for the inhibition of Glycinamide ribonucleotide formyl transferase (GAR) with formyl (6R) tetrahydrofolate as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTrifunctional purine biosynthetic protein adenosine-3(Mouse)
University of South Alabama

Curated by ChEMBL
LigandPNGBDBM50014707(CHEMBL431359 | 2-{4-[2-(2,4-Diamino-pteridin-6-yl)...)
Affinity DataIC50: 5.00E+4nMAssay Description:Concentration inhibiting GAR transformylase enzyme of Lactobacillus caseiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTrifunctional purine biosynthetic protein adenosine-3(Mouse)
University of South Alabama

Curated by ChEMBL
LigandPNGBDBM50022741((5RS, 6RS) 2-{4-[2-(2-Amino-5-methyl-4-oxo-3,4,5,6...)
Affinity DataIC50: 8.00E+4nMAssay Description:Inhibition of GAR transformylase from mammalian L1210 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTrifunctional purine biosynthetic protein adenosine-3(Mouse)
University of South Alabama

Curated by ChEMBL
LigandPNGBDBM50003058(CHEMBL331208 | 2-[4-(7-Amino-9-oxo-8,9-dihydro-2,5...)
Affinity DataIC50: 9.50E+4nMAssay Description:Compound was evaluated for the inhibition of Glycinamide ribonucleotide formyl transferase (GAR) with formyl (6R) tetrahydrofolate as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTrifunctional purine biosynthetic protein adenosine-3(Mouse)
University of South Alabama

Curated by ChEMBL
LigandPNGBDBM50003057(CHEMBL122959 | 7-Amino-1,2,3-trimethyl-2,8-dihydro...)
Affinity DataIC50: 9.50E+4nMAssay Description:Compound was evaluated for the inhibition of Glycinamide ribonucleotide formyl transferase (GAR) with formyl (6R) tetrahydrofolate as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTrifunctional purine biosynthetic protein adenosine-3(Mouse)
University of South Alabama

Curated by ChEMBL
LigandPNGBDBM50171511(N-{4-[4-(2-Amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-...)
Affinity DataIC50: 1.50E+5nMAssay Description:Inhibition of mouse recombinant GARFtase assessed as FGAR formation by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetTrifunctional purine biosynthetic protein adenosine-3(Mouse)
University of South Alabama

Curated by ChEMBL
LigandPNGBDBM50249877((S)-2-(4-(4-(2-amino-4-oxo-3,4-dihydrothieno[2,3-d...)
Affinity DataIC50: 5.51E+6nMAssay Description:Inhibition of mouse recombinant GARFtase assessed as FGAR formation by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed