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Report error Found 199 of kd for UniProtKB: P42226
TargetSignal transducer and activator of transcription 6(Human)
Gilead Sciences

US Patent
LigandPNGBDBM784518(2-Amino-5-[2-[[4-[4- (dimethylcarbamoyl)phenyl]-1-...)
Affinity DataKd:  9.05nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/25/2026
Entry Details US Patent

TargetSignal transducer and activator of transcription 6(Human)
Gilead Sciences

US Patent
LigandPNGBDBM50557878(CHEMBL4776801)
Affinity DataKd: >10nMAssay Description:Binding affinity to human recombinant STAT6 assessed as dissociation constant incubated for 15 mins by biolayer interferometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetSignal transducer and activator of transcription 6(Human)
Gilead Sciences

US Patent
LigandPNGBDBM784494(Ethyl 6-amino-3-[2-[[4-[4- (dimethylcarbamoyl)phen...)
Affinity DataKd:  11nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/25/2026
Entry Details US Patent

TargetSignal transducer and activator of transcription 6(Human)
Gilead Sciences

US Patent
LigandPNGBDBM784488(4-[1-[[4-(6-Amino-3-pyridyl)-1- methyl-pyrrolo[2,3...)
Affinity DataKd:  11.4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/25/2026
Entry Details US Patent

TargetSignal transducer and activator of transcription 6(Human)
Gilead Sciences

US Patent
LigandPNGBDBM782768(US20250325677, Example 3p1)
Affinity DataKd:  11.4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/11/2026
Entry Details US Patent

TargetSignal transducer and activator of transcription 6(Human)
Gilead Sciences

US Patent
LigandPNGBDBM784465(2-(2-Amino-5-(2-((4-(4- (dimethylcarbamoyl)phenyl)...)
Affinity DataKd:  12.8nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/25/2026
Entry Details US Patent

TargetSignal transducer and activator of transcription 6(Human)
Gilead Sciences

US Patent
LigandPNGBDBM784429(US20250340551, Example 1af12)
Affinity DataKd:  12.9nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/25/2026
Entry Details US Patent

TargetSignal transducer and activator of transcription 6(Human)
Gilead Sciences

US Patent
LigandPNGBDBM784526(4-[1-[[4-(6-Aminopyridazin-3-yl)-1- methyl-pyrrolo...)
Affinity DataKd:  13.5nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/25/2026
Entry Details US Patent

TargetSignal transducer and activator of transcription 6(Human)
Gilead Sciences

US Patent
LigandPNGBDBM784464(US20250340551, Example 1af8)
Affinity DataKd:  14.6nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/25/2026
Entry Details US Patent

TargetSignal transducer and activator of transcription 6(Human)
Gilead Sciences

US Patent
LigandPNGBDBM784450(US20250340551, Example 1af33)
Affinity DataKd:  15.4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/25/2026
Entry Details US Patent

TargetSignal transducer and activator of transcription 6(Human)
Gilead Sciences

US Patent
LigandPNGBDBM784433(US20250340551, Example 1af16)
Affinity DataKd:  15.5nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/25/2026
Entry Details US Patent

TargetSignal transducer and activator of transcription 6(Human)
Gilead Sciences

US Patent
LigandPNGBDBM784453(US20250340551, Example 1af36)
Affinity DataKd:  15.7nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/25/2026
Entry Details US Patent

TargetSignal transducer and activator of transcription 6(Human)
Gilead Sciences

US Patent
LigandPNGBDBM784496(N,N-Dimethyl-4-[1-[1-methyl-4-[6- (methylamino)-3-...)
Affinity DataKd:  16nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/25/2026
Entry Details US Patent

TargetSignal transducer and activator of transcription 6(Human)
Gilead Sciences

US Patent
LigandPNGBDBM784601(N,N,3-Trimethyl-4-[1-[[1-methyl-4-[5- (methylamino...)
Affinity DataKd:  16nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/25/2026
Entry Details US Patent

TargetSignal transducer and activator of transcription 6(Human)
Gilead Sciences

US Patent
LigandPNGBDBM784521(2-[[5-[2-[[4-[4- (Dimethylcarbamoyl)phenyl]-1- pip...)
Affinity DataKd:  16.3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/25/2026
Entry Details US Patent

TargetSignal transducer and activator of transcription 6(Human)
Gilead Sciences

US Patent
LigandPNGBDBM784520(4-[1-[[4-[6-(2-Hydroxyethylamino)-3- pyridyl]-1-me...)
Affinity DataKd:  16.5nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/25/2026
Entry Details US Patent

TargetSignal transducer and activator of transcription 6(Human)
Gilead Sciences

US Patent
LigandPNGBDBM784485(Methyl 2-[[5-[2-[[4-[4- (dimethylcarbamoyl)phenyl]...)
Affinity DataKd:  16.8nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/25/2026
Entry Details US Patent

TargetSignal transducer and activator of transcription 6(Human)
Gilead Sciences

US Patent
LigandPNGBDBM784570(N,N-Dimethyl-4-[(2R,4R)-1-[[4-(5- amino-2-pyridyl)...)
Affinity DataKd:  18.1nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/25/2026
Entry Details US Patent

TargetSignal transducer and activator of transcription 6(Human)
Gilead Sciences

US Patent
LigandPNGBDBM784573(N,N-Dimethyl-4-[(2R,4R)-1-[[4-(6- amino-2-cyano-3-...)
Affinity DataKd:  18.4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/25/2026
Entry Details US Patent

TargetSignal transducer and activator of transcription 6(Human)
Gilead Sciences

US Patent
LigandPNGBDBM784431(US20250340551, Example 1af14)
Affinity DataKd:  18.5nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/25/2026
Entry Details US Patent

TargetSignal transducer and activator of transcription 6(Human)
Gilead Sciences

US Patent
LigandPNGBDBM784451(US20250340551, Example 1af34)
Affinity DataKd:  18.6nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/25/2026
Entry Details US Patent

TargetSignal transducer and activator of transcription 6(Human)
Gilead Sciences

US Patent
LigandPNGBDBM784524(4-(1-((4-(5-Aminopyridin-2-yl)-1- methyl-1H-pyrrol...)
Affinity DataKd:  18.8nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/25/2026
Entry Details US Patent

TargetSignal transducer and activator of transcription 6(Human)
Gilead Sciences

US Patent
LigandPNGBDBM784567(N,N,3-Trimethyl-4-[4-[[1-methyl-4-[6- (methylamino...)
Affinity DataKd:  19.2nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/25/2026
Entry Details US Patent

TargetSignal transducer and activator of transcription 6(Human)
Gilead Sciences

US Patent
LigandPNGBDBM784443(US20250340551, Example 1af26)
Affinity DataKd:  20nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/25/2026
Entry Details US Patent

TargetSignal transducer and activator of transcription 6(Human)
Gilead Sciences

US Patent
LigandPNGBDBM784470(4-[1-[[4-(6-Amino-2-methyl-3- pyridyl)-1-methyl-py...)
Affinity DataKd:  20.1nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/25/2026
Entry Details US Patent

TargetSignal transducer and activator of transcription 6(Human)
Gilead Sciences

US Patent
LigandPNGBDBM784592(US20250340551, Example 1s28)
Affinity DataKd:  20.6nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/25/2026
Entry Details US Patent

TargetSignal transducer and activator of transcription 6(Human)
Gilead Sciences

US Patent
LigandPNGBDBM784461(US20250340551, Example 1af45)
Affinity DataKd:  21.6nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/25/2026
Entry Details US Patent

TargetSignal transducer and activator of transcription 6(Human)
Gilead Sciences

US Patent
LigandPNGBDBM784569(N,N,3-Trimethyl-4-[1-[[1-methyl-4-[6- (methylamino...)
Affinity DataKd:  22nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/25/2026
Entry Details US Patent

TargetSignal transducer and activator of transcription 6(Human)
Gilead Sciences

US Patent
LigandPNGBDBM784594(3-Fluoro-N,N-dimethyl-4-(1-((1- methyl-4-(6-(methy...)
Affinity DataKd:  22.1nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/25/2026
Entry Details US Patent

TargetSignal transducer and activator of transcription 6(Human)
Gilead Sciences

US Patent
LigandPNGBDBM784481(4-[1-[[4-(6-Amino-2-methoxy-3- pyridyl)-1-methyl-p...)
Affinity DataKd:  22.3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/25/2026
Entry Details US Patent

TargetSignal transducer and activator of transcription 6(Human)
Gilead Sciences

US Patent
LigandPNGBDBM784607(4-(1-((4-(6-aminopyridin-3-yl)-1- methyl-1H-pyrrol...)
Affinity DataKd:  22.3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/25/2026
Entry Details US Patent

TargetSignal transducer and activator of transcription 6(Human)
Gilead Sciences

US Patent
LigandPNGBDBM784606(N,N-dimethyl-4-(1-(1-(1-methyl-4-(6- (methylamino)...)
Affinity DataKd:  22.3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/25/2026
Entry Details US Patent

TargetSignal transducer and activator of transcription 6(Human)
Gilead Sciences

US Patent
LigandPNGBDBM784530(N,N-Dimethyl-4-[1-[[1-methyl-4-[6- (methylamino)py...)
Affinity DataKd:  22.6nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/25/2026
Entry Details US Patent

TargetSignal transducer and activator of transcription 6(Human)
Gilead Sciences

US Patent
LigandPNGBDBM784474(4-[1-[[4-(6-Amino-4-fluoro-3-pyridyl)- 1-methyl-py...)
Affinity DataKd:  22.6nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/25/2026
Entry Details US Patent

TargetSignal transducer and activator of transcription 6(Human)
Gilead Sciences

US Patent
LigandPNGBDBM784593(N,N-Dimethyl-4-[(4R)-1-[[1-methyl-4- [6-(methylami...)
Affinity DataKd:  23.2nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/25/2026
Entry Details US Patent

TargetSignal transducer and activator of transcription 6(Human)
Gilead Sciences

US Patent
LigandPNGBDBM784602(4-[1-[[4-(5-Amino-1-oxido-pyridin-1- ium-2-yl)-1-m...)
Affinity DataKd:  23.9nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/25/2026
Entry Details US Patent

TargetSignal transducer and activator of transcription 6(Human)
Gilead Sciences

US Patent
LigandPNGBDBM784447(US20250340551, Example 1af30)
Affinity DataKd:  24.1nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/25/2026
Entry Details US Patent

TargetSignal transducer and activator of transcription 6(Human)
Gilead Sciences

US Patent
LigandPNGBDBM784409((R)-N,N-Dimethyl-4-[1-[[4-(6-amino- 3-pyridyl)-1-m...)
Affinity DataKd:  24.5nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/25/2026
Entry Details US Patent

TargetSignal transducer and activator of transcription 6(Human)
Gilead Sciences

US Patent
LigandPNGBDBM784405(4-[1-[[4-(5-Amino-2-pyridyl)-1- methyl-pyrrolo[2,3...)
Affinity DataKd:  25.4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/25/2026
Entry Details US Patent

TargetSignal transducer and activator of transcription 6(Human)
Gilead Sciences

US Patent
LigandPNGBDBM784482(4-[1-[[4-(6-Amino-2-methoxy-3- pyridyl)-1-methyl-p...)
Affinity DataKd:  25.5nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/25/2026
Entry Details US Patent

TargetSignal transducer and activator of transcription 6(Human)
Gilead Sciences

US Patent
LigandPNGBDBM784503(4-[1-[[4-(6-Amino-2-methoxy-3- pyridyl)-1-methyl-p...)
Affinity DataKd:  25.6nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/25/2026
Entry Details US Patent

TargetSignal transducer and activator of transcription 6(Human)
Gilead Sciences

US Patent
LigandPNGBDBM784504(4-[1-[[4-(6-Amino-2-cyano-3-pyridyl)- 1-(trideuter...)
Affinity DataKd:  27.7nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/25/2026
Entry Details US Patent

TargetSignal transducer and activator of transcription 6(Human)
Gilead Sciences

US Patent
LigandPNGBDBM784497(4-[1-[[1-Methyl-4-[6-(methylamino)- 3-pyridyl]pyrr...)
Affinity DataKd:  27.7nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/25/2026
Entry Details US Patent

TargetSignal transducer and activator of transcription 6(Human)
Gilead Sciences

US Patent
LigandPNGBDBM784584(N,N,3,5-Tetramethyl-4-[1-[[1-methyl- 4-[6-(methyla...)
Affinity DataKd:  28.8nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/25/2026
Entry Details US Patent

TargetSignal transducer and activator of transcription 6(Human)
Gilead Sciences

US Patent
LigandPNGBDBM784585(N,N,3-Trimethyl-4-[4-[[1-methyl-4-[6- (methylamino...)
Affinity DataKd:  28.9nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/25/2026
Entry Details US Patent

TargetSignal transducer and activator of transcription 6(Human)
Gilead Sciences

US Patent
LigandPNGBDBM784603(N,N-Dimethyl-4-[1-[[4-[6- (methylamino)-3-pyridyl]...)
Affinity DataKd:  29.5nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/25/2026
Entry Details US Patent

TargetSignal transducer and activator of transcription 6(Human)
Gilead Sciences

US Patent
LigandPNGBDBM784469(4-[1-[[4-(6-Amino-5-methyl-3- pyridyl)-1-methyl-py...)
Affinity DataKd:  30.5nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/25/2026
Entry Details US Patent

TargetSignal transducer and activator of transcription 6(Human)
Gilead Sciences

US Patent
LigandPNGBDBM784554(3-Fluoro-N,N-dimethyl-4-[1-[[1- methyl-4-[5-(methy...)
Affinity DataKd:  30.6nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/25/2026
Entry Details US Patent

TargetSignal transducer and activator of transcription 6(Human)
Gilead Sciences

US Patent
LigandPNGBDBM784555((S)-N,N-dimethyl-4-(1-(1-(1-methyl-4- (5-(methylam...)
Affinity DataKd:  31.2nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/25/2026
Entry Details US Patent

TargetSignal transducer and activator of transcription 6(Human)
Gilead Sciences

US Patent
LigandPNGBDBM784502(4-[1-[[4-(6-Amino-2-cyano-3-pyridyl)- 1-methyl-pyr...)
Affinity DataKd:  31.4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/25/2026
Entry Details US Patent

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