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Found 3 of ic50 for UniProtKB: A2CF88
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Mus musculus)
Kyoto Prefectural University Of Medicine

Curated by ChEMBL
LigandPNGBDBM50085045(5-((4-((6-hydroxy-2,5,7,8-tetramethyl-3,4-dihydro-...)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of 15-LOX-mediated lipid oxidation in 10% C57BL/6J mouse plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Mus musculus)
Kyoto Prefectural University Of Medicine

Curated by ChEMBL
LigandPNGBDBM50200541(CHEBI:31530 | Edaravone | MCI-186 | Radicava | Rad...)
Affinity DataIC50:  3.40E+4nMAssay Description:Inhibition of 15-LOX-mediated lipid oxidation in 10% C57BL/6J mouse plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Mus musculus)
Kyoto Prefectural University Of Medicine

Curated by ChEMBL
LigandPNGBDBM50350396(CHEMBL1573436)
Affinity DataIC50: >1.50E+5nMAssay Description:Inhibition of mouse N-terminally His6-tagged 15-lipoxygenase expressed in SF9 insect cells assessed as 15-HPETE formation using arachidonic acid by U...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed