Compile Data Set for Download or QSAR
Report error Found 14 of ec50 for UniProtKB: P30561
TargetAryl hydrocarbon receptor(Mouse)
Pfizer

Curated by ChEMBL
LigandPNGBDBM23927(Tetrachlorodibenzodioxin | 2,3,7,8-Tetrachlorodibe...)
Affinity DataEC50:  0.0300nMAssay Description:Agonist activity at Ah receptor in genetically engineered mouse cells expressing firefly luciferase gene by CALUX transactivational assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetAryl hydrocarbon receptor(Mouse)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50602335(CHEMBL5186309)
Affinity DataEC50:  0.0580nMAssay Description:Activation of AhR in mouse NIH3T3 cells assessed as induction of XRE-dependent reporter activity incubated for 4 hrs by Renilla/Firefly based dual-lu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetAryl hydrocarbon receptor(Mouse)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50506039(CHEMBL1324296 | US11891386, Compound 002)
Affinity DataEC50:  10nMAssay Description:Agonist activity at AhR in mouse Hepa2Dluc cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAryl hydrocarbon receptor(Mouse)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50602335(CHEMBL5186309)
Affinity DataEC50:  71nMAssay Description:Activation of AhR in mouse Hepa1c1c7 cells assessed as induction of XRE-dependent reporter activity incubated for 4 hrs by Renilla/Firefly based dual...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetAryl hydrocarbon receptor(Mouse)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50015301(CHEMBL3263111)
Affinity DataEC50:  1.20E+3nMAssay Description:Agonist activity at AHR in FVB/N mouse primary mammary epithelial cells assessed as blockade of mammary branching morphogenesis after 144 hrs by micr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetAryl hydrocarbon receptor(Mouse)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50015302(CHEMBL3263112)
Affinity DataEC50:  1.40E+3nMAssay Description:Agonist activity at AHR in FVB/N mouse primary mammary epithelial cells assessed as blockade of mammary branching morphogenesis after 144 hrs by micr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetAryl hydrocarbon receptor(Mouse)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50015303(CHEMBL3263118)
Affinity DataEC50:  2.20E+3nMAssay Description:Agonist activity at AHR in FVB/N mouse primary mammary epithelial cells assessed as blockade of mammary branching morphogenesis after 144 hrs by micr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetAryl hydrocarbon receptor(Mouse)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50015304(CHEMBL3263119)
Affinity DataEC50:  3.20E+3nMAssay Description:Agonist activity at AHR in FVB/N mouse primary mammary epithelial cells assessed as blockade of mammary branching morphogenesis after 144 hrs by micr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetAryl hydrocarbon receptor(Mouse)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50357344(CHEMBL1916902)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at Ah receptor in genetically engineered mouse cells expressing firefly luciferase gene by CALUX transactivational assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetAryl hydrocarbon receptor(Mouse)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50015305(CHEMBL3263120)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at AHR in FVB/N mouse primary mammary epithelial cells assessed as blockade of mammary branching morphogenesis after 144 hrs by micr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetAryl hydrocarbon receptor(Mouse)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50357339(CHEMBL1916897)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at Ah receptor in genetically engineered mouse cells expressing firefly luciferase gene by CALUX transactivational assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetAryl hydrocarbon receptor(Mouse)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50357333(CHEMBL1916891)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at Ah receptor in genetically engineered mouse cells expressing firefly luciferase gene by CALUX transactivational assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetAryl hydrocarbon receptor(Mouse)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50357322(CHEMBL1916880)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at Ah receptor in genetically engineered mouse cells expressing firefly luciferase gene by CALUX transactivational assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetAryl hydrocarbon receptor(Mouse)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50239186(CHEBI:50182 | 1,1-Bis(3''-Indolyl)Methane | 3,3''-...)
Affinity DataEC50:  7.80E+4nMAssay Description:Displacement of 2-azido-3-[125I]7,8-dibromodibenzo-pdioxin from C57BL/6J mouse liver AhR relative to TCDDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed