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Report error Found 10 of ic50 data for polymerid = 5288
Target25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial(Human)
Cardiff University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50261586BDBM50261586(CHEMBL4099180)
Affinity DataIC50: 60nMAssay Description:Inhibition of human CYP27B1 expressed in Escherichia coli assessed as reduction in hydrolase activity incubated for 25 mins using Adx, AdR and 1,25(O...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details Article
PubMed
Target25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial(Human)
Cardiff University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50261589BDBM50261589(CHEMBL4081152)
Affinity DataIC50: 95nMAssay Description:Inhibition of human CYP27B1 expressed in Escherichia coli assessed as reduction in hydrolase activity incubated for 25 mins using Adx, AdR and 1,25(O...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details Article
PubMed
Target25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial(Human)
Cardiff University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 151585BDBM151585(US8987315, Ketoconazole | US9180183, Ketoconazole ...)
Affinity DataIC50: 340nMAssay Description:Inhibition of human CYP27B1 expressed in Escherichia coli assessed as reduction in hydrolase activity incubated for 25 mins using Adx, AdR and 1,25(O...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details Article
PubMed
Target25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial(Human)
Cardiff University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50261588BDBM50261588(CHEMBL4074768)
Affinity DataIC50: 410nMAssay Description:Inhibition of human CYP27B1 expressed in Escherichia coli assessed as reduction in hydrolase activity incubated for 25 mins using Adx, AdR and 1,25(O...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details Article
PubMed
Target25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial(Human)
Cardiff University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50214607BDBM50214607(MK-24 | MK-24(S)-S(O)(NH)Ph | CHEMBL541423)
Affinity DataIC50: 554nMAssay Description:Inhibition of CYP27B1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
Target25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial(Human)
Cardiff University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50556038BDBM50556038(CHEMBL389014)
Affinity DataIC50: 554nMAssay Description:Inhibition of CYP27B in human SW900 cells using 3H-(23,24)-25-(OH)D3 as substrate incubated for 5 hrs by HPLC methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
Target25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial(Human)
Cardiff University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50370925BDBM50370925(CHEMBL1627233)
Affinity DataIC50: 554nMAssay Description:Inhibition of human CYP27B hydroxylase expressed in SW900 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
Target25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial(Human)
Cardiff University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50261587BDBM50261587(CHEMBL4104395)
Affinity DataIC50: 570nMAssay Description:Inhibition of human CYP27B1 expressed in Escherichia coli assessed as reduction in hydrolase activity incubated for 25 mins using Adx, AdR and 1,25(O...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details Article
PubMed
Target25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial(Human)
Cardiff University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50214606BDBM50214606(Azole, 12 | CHEMBL253613 | 4'-chloro-biphenyl-4-ca...)
Affinity DataIC50: 616nMAssay Description:Inhibition of CYP27B1 in human keratinocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
Target25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial(Human)
Cardiff University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50322358BDBM50322358(4'-Chloro-biphenyl-4-carboxylic acid((R)-2-imidazo...)
Affinity DataIC50: 616nMAssay Description:Inhibition of human CYP27B1 expressed in Escherichia coli assessed as reduction in hydrolase activity incubated for 25 mins using Adx, AdR and 1,25(O...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details Article
PubMed