Compile Data Set for Download or QSAR
maximum 50k data
Found 78 of ic50 for UniProtKB: A0A384MEG1
TargetFascin(Homo sapiens (human))
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM50526225(CHEMBL4452711)
Affinity DataIC50:  240nMAssay Description:Inhibition of human (His8)2-tagged fascin (1 to 493 residues) expressed in Escherichia coli BL21(DE3) pLysS assessed as reduction in F-actin bundling...More data for this Ligand-Target Pair
TargetFascin(Homo sapiens (human))
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM50526241(CHEMBL4461540)
Affinity DataIC50:  330nMAssay Description:Inhibition of human (His8)2-tagged fascin (1 to 493 residues) expressed in Escherichia coli BL21(DE3) pLysS assessed as reduction in F-actin bundling...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFascin(Homo sapiens (human))
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM350103((Z)-N-(2,3-diphenyl-1,2,4- thiadiazol-5(2H)- ylide...)
Affinity DataIC50:  500nMAssay Description:About 150,000 compounds were screened. These chemical compounds were from the LOPAC 1280 collection, the Prestwick chemical library, the Pharmakon co...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFascin(Homo sapiens (human))
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM350104(N-methyl-2,3-diphenyl- 1,2,4-thiadiazolium-5- amin...)
Affinity DataIC50:  500nMAssay Description:About 150,000 compounds were screened. These chemical compounds were from the LOPAC 1280 collection, the Prestwick chemical library, the Pharmakon co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFascin(Homo sapiens (human))
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM350103((Z)-N-(2,3-diphenyl-1,2,4- thiadiazol-5(2H)- ylide...)
Affinity DataIC50:  500nMAssay Description:A high throughput assay was developed to screen for fascin specific inhibitors. Purified polymerized F-actin with or without fascin were mixed and in...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFascin(Homo sapiens (human))
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM350104(N-methyl-2,3-diphenyl- 1,2,4-thiadiazolium-5- amin...)
Affinity DataIC50:  500nMAssay Description:A high throughput assay was developed to screen for fascin specific inhibitors. Purified polymerized F-actin with or without fascin were mixed and in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFascin(Homo sapiens (human))
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM50526227(CHEMBL4574198)
Affinity DataIC50:  510nMAssay Description:Inhibition of human (His8)2-tagged fascin (1 to 493 residues) expressed in Escherichia coli BL21(DE3) pLysS assessed as reduction in F-actin bundling...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFascin(Homo sapiens (human))
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM350111(N-(3-(1H-1,2,4-triazol-3- ylthio)-4- hydroxynaphth...)
Affinity DataIC50:  539nMAssay Description:A high throughput assay was developed to screen for fascin specific inhibitors. Purified polymerized F-actin with or without fascin were mixed and in...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFascin(Homo sapiens (human))
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM350111(N-(3-(1H-1,2,4-triazol-3- ylthio)-4- hydroxynaphth...)
Affinity DataIC50:  539nMAssay Description:About 150,000 compounds were screened. These chemical compounds were from the LOPAC 1280 collection, the Prestwick chemical library, the Pharmakon co...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFascin(Homo sapiens (human))
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM50526240(CHEMBL4566108)
Affinity DataIC50:  630nMAssay Description:Inhibition of human (His8)2-tagged fascin (1 to 493 residues) expressed in Escherichia coli BL21(DE3) pLysS assessed as reduction in F-actin bundling...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFascin(Homo sapiens (human))
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM50526226(CHEMBL4559691)
Affinity DataIC50:  630nMAssay Description:Inhibition of human (His8)2-tagged fascin (1 to 493 residues) expressed in Escherichia coli BL21(DE3) pLysS assessed as reduction in F-actin bundling...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFascin(Homo sapiens (human))
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM350102(2-chloro-N-(6- chlorobenzo[d]thiazol-2- yl)-5- nit...)
Affinity DataIC50:  652nMAssay Description:A high throughput assay was developed to screen for fascin specific inhibitors. Purified polymerized F-actin with or without fascin were mixed and in...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFascin(Homo sapiens (human))
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM350102(2-chloro-N-(6- chlorobenzo[d]thiazol-2- yl)-5- nit...)
Affinity DataIC50:  652nMAssay Description:About 150,000 compounds were screened. These chemical compounds were from the LOPAC 1280 collection, the Prestwick chemical library, the Pharmakon co...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFascin(Homo sapiens (human))
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM350107(N-(3-(1H-1,2,4-triazol-3- ylthio)-4- hydroxynaphth...)
Affinity DataIC50:  683nMAssay Description:A high throughput assay was developed to screen for fascin specific inhibitors. Purified polymerized F-actin with or without fascin were mixed and in...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFascin(Homo sapiens (human))
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM350107(N-(3-(1H-1,2,4-triazol-3- ylthio)-4- hydroxynaphth...)
Affinity DataIC50:  683nMAssay Description:About 150,000 compounds were screened. These chemical compounds were from the LOPAC 1280 collection, the Prestwick chemical library, the Pharmakon co...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFascin(Homo sapiens (human))
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM350100(5-(3,4-dichlorobenzyl)-1- (S,S,-dioxo- tetrahydrot...)
Affinity DataIC50:  734nMAssay Description:A high throughput assay was developed to screen for fascin specific inhibitors. Purified polymerized F-actin with or without fascin were mixed and in...More data for this Ligand-Target Pair
TargetFascin(Homo sapiens (human))
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM350100(5-(3,4-dichlorobenzyl)-1- (S,S,-dioxo- tetrahydrot...)
Affinity DataIC50:  734nMAssay Description:About 150,000 compounds were screened. These chemical compounds were from the LOPAC 1280 collection, the Prestwick chemical library, the Pharmakon co...More data for this Ligand-Target Pair
TargetFascin(Homo sapiens (human))
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM350109(N-(3-(1H-1,2,4-triazol-3- ylthio)-4- hydroxynaphth...)
Affinity DataIC50:  807nMAssay Description:About 150,000 compounds were screened. These chemical compounds were from the LOPAC 1280 collection, the Prestwick chemical library, the Pharmakon co...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFascin(Homo sapiens (human))
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM350109(N-(3-(1H-1,2,4-triazol-3- ylthio)-4- hydroxynaphth...)
Affinity DataIC50:  807nMAssay Description:A high throughput assay was developed to screen for fascin specific inhibitors. Purified polymerized F-actin with or without fascin were mixed and in...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFascin(Homo sapiens (human))
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM350110(N-(3-(1H-1,2,4-triazol-3- ylthio)-4- hydroxynaphth...)
Affinity DataIC50:  890nMAssay Description:About 150,000 compounds were screened. These chemical compounds were from the LOPAC 1280 collection, the Prestwick chemical library, the Pharmakon co...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFascin(Homo sapiens (human))
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM350110(N-(3-(1H-1,2,4-triazol-3- ylthio)-4- hydroxynaphth...)
Affinity DataIC50:  890nMAssay Description:A high throughput assay was developed to screen for fascin specific inhibitors. Purified polymerized F-actin with or without fascin were mixed and in...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFascin(Homo sapiens (human))
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM350120(5-(3-chlorobenzyl)-1-(2- hydroxyethyl)-1H- pyrazol...)
Affinity DataIC50:  1.20E+3nMAssay Description:About 150,000 compounds were screened. These chemical compounds were from the LOPAC 1280 collection, the Prestwick chemical library, the Pharmakon co...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFascin(Homo sapiens (human))
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM350120(5-(3-chlorobenzyl)-1-(2- hydroxyethyl)-1H- pyrazol...)
Affinity DataIC50:  1.20E+3nMAssay Description:A high throughput assay was developed to screen for fascin specific inhibitors. Purified polymerized F-actin with or without fascin were mixed and in...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFascin(Homo sapiens (human))
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM50526224(CHEMBL4451624)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of human (His8)2-tagged fascin (1 to 493 residues) expressed in Escherichia coli BL21(DE3) pLysS assessed as reduction in F-actin bundling...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetFascin(Homo sapiens (human))
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM350108(N-(3-(1H-1,2,4-triazol-3- ylthio)-4- hydroxynaphth...)
Affinity DataIC50:  1.47E+3nMAssay Description:About 150,000 compounds were screened. These chemical compounds were from the LOPAC 1280 collection, the Prestwick chemical library, the Pharmakon co...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFascin(Homo sapiens (human))
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM350108(N-(3-(1H-1,2,4-triazol-3- ylthio)-4- hydroxynaphth...)
Affinity DataIC50:  1.47E+3nMAssay Description:A high throughput assay was developed to screen for fascin specific inhibitors. Purified polymerized F-actin with or without fascin were mixed and in...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFascin(Homo sapiens (human))
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM350106(N-phenyl-2,3-diphenyl- 1,2,4-thiadiazolium-5- amin...)
Affinity DataIC50:  2.00E+3nMAssay Description:A high throughput assay was developed to screen for fascin specific inhibitors. Purified polymerized F-actin with or without fascin were mixed and in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFascin(Homo sapiens (human))
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM350112((Z)-N-(3-(1H-1,2,4-triazol- 3-ylthio)-4-oxonaphtha...)
Affinity DataIC50:  2.00E+3nMAssay Description:About 150,000 compounds were screened. These chemical compounds were from the LOPAC 1280 collection, the Prestwick chemical library, the Pharmakon co...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFascin(Homo sapiens (human))
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM350128(5-(3,4-dichlorobenzyl)-1- o-tolyl-1H-pyrazolo[3,4-...)
Affinity DataIC50:  2.00E+3nMAssay Description:A high throughput assay was developed to screen for fascin specific inhibitors. Purified polymerized F-actin with or without fascin were mixed and in...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFascin(Homo sapiens (human))
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM350101(N-(1-(4- (trifluoromethyl)benzyl)- 1H-indazol-3-yl...)
Affinity DataIC50:  2.00E+3nMAssay Description:A high throughput assay was developed to screen for fascin specific inhibitors. Purified polymerized F-actin with or without fascin were mixed and in...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFascin(Homo sapiens (human))
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM350128(5-(3,4-dichlorobenzyl)-1- o-tolyl-1H-pyrazolo[3,4-...)
Affinity DataIC50:  2.00E+3nMAssay Description:About 150,000 compounds were screened. These chemical compounds were from the LOPAC 1280 collection, the Prestwick chemical library, the Pharmakon co...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFascin(Homo sapiens (human))
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM350101(N-(1-(4- (trifluoromethyl)benzyl)- 1H-indazol-3-yl...)
Affinity DataIC50:  2.00E+3nMAssay Description:About 150,000 compounds were screened. These chemical compounds were from the LOPAC 1280 collection, the Prestwick chemical library, the Pharmakon co...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFascin(Homo sapiens (human))
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM350112((Z)-N-(3-(1H-1,2,4-triazol- 3-ylthio)-4-oxonaphtha...)
Affinity DataIC50:  2.00E+3nMAssay Description:A high throughput assay was developed to screen for fascin specific inhibitors. Purified polymerized F-actin with or without fascin were mixed and in...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFascin(Homo sapiens (human))
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM350118(N-(6- chlorobenzo[d]thiazol-2- yl)acetamide | US10...)
Affinity DataIC50:  2.00E+3nMAssay Description:A high throughput assay was developed to screen for fascin specific inhibitors. Purified polymerized F-actin with or without fascin were mixed and in...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFascin(Homo sapiens (human))
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM350118(N-(6- chlorobenzo[d]thiazol-2- yl)acetamide | US10...)
Affinity DataIC50:  2.00E+3nMAssay Description:About 150,000 compounds were screened. These chemical compounds were from the LOPAC 1280 collection, the Prestwick chemical library, the Pharmakon co...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFascin(Homo sapiens (human))
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM350106(N-phenyl-2,3-diphenyl- 1,2,4-thiadiazolium-5- amin...)
Affinity DataIC50:  2.00E+3nMAssay Description:About 150,000 compounds were screened. These chemical compounds were from the LOPAC 1280 collection, the Prestwick chemical library, the Pharmakon co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFascin(Homo sapiens (human))
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM350130(5-(3,4-dichlorobenzyl)-1- (2,4-dimethylphenyl)-1H-...)
Affinity DataIC50:  2.10E+3nMAssay Description:About 150,000 compounds were screened. These chemical compounds were from the LOPAC 1280 collection, the Prestwick chemical library, the Pharmakon co...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFascin(Homo sapiens (human))
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM50526230(CHEMBL4457641)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of human (His8)2-tagged fascin (1 to 493 residues) expressed in Escherichia coli BL21(DE3) pLysS assessed as reduction in F-actin bundling...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFascin(Homo sapiens (human))
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM350130(5-(3,4-dichlorobenzyl)-1- (2,4-dimethylphenyl)-1H-...)
Affinity DataIC50:  2.10E+3nMAssay Description:A high throughput assay was developed to screen for fascin specific inhibitors. Purified polymerized F-actin with or without fascin were mixed and in...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFascin(Homo sapiens (human))
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM350129(5-(3,4-dichlorobenzyl)-1- (2,3-dimethylphenyl)-1H-...)
Affinity DataIC50:  2.30E+3nMAssay Description:A high throughput assay was developed to screen for fascin specific inhibitors. Purified polymerized F-actin with or without fascin were mixed and in...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFascin(Homo sapiens (human))
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM350129(5-(3,4-dichlorobenzyl)-1- (2,3-dimethylphenyl)-1H-...)
Affinity DataIC50:  2.30E+3nMAssay Description:About 150,000 compounds were screened. These chemical compounds were from the LOPAC 1280 collection, the Prestwick chemical library, the Pharmakon co...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFascin(Homo sapiens (human))
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM50076451(CHEMBL3235887 | US10208043, # 14 | US10941146, # 1...)
Affinity DataIC50:  2.62E+3nMAssay Description:About 150,000 compounds were screened. These chemical compounds were from the LOPAC 1280 collection, the Prestwick chemical library, the Pharmakon co...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFascin(Homo sapiens (human))
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM50076451(CHEMBL3235887 | US10208043, # 14 | US10941146, # 1...)
Affinity DataIC50:  2.62E+3nMAssay Description:A high throughput assay was developed to screen for fascin specific inhibitors. Purified polymerized F-actin with or without fascin were mixed and in...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFascin(Homo sapiens (human))
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM350114(N-(3-(1H-1,2,4-triazol-3- ylthio)-4- hydroxynaphth...)
Affinity DataIC50:  2.70E+3nMAssay Description:About 150,000 compounds were screened. These chemical compounds were from the LOPAC 1280 collection, the Prestwick chemical library, the Pharmakon co...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFascin(Homo sapiens (human))
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM350114(N-(3-(1H-1,2,4-triazol-3- ylthio)-4- hydroxynaphth...)
Affinity DataIC50:  2.70E+3nMAssay Description:A high throughput assay was developed to screen for fascin specific inhibitors. Purified polymerized F-actin with or without fascin were mixed and in...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFascin(Homo sapiens (human))
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM350121(2-(4-oxo-1-(S,S,-dioxo- tetrahydrothiophen-3-yl)- ...)
Affinity DataIC50:  3.40E+3nMAssay Description:A high throughput assay was developed to screen for fascin specific inhibitors. Purified polymerized F-actin with or without fascin were mixed and in...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFascin(Homo sapiens (human))
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM350121(2-(4-oxo-1-(S,S,-dioxo- tetrahydrothiophen-3-yl)- ...)
Affinity DataIC50:  3.40E+3nMAssay Description:About 150,000 compounds were screened. These chemical compounds were from the LOPAC 1280 collection, the Prestwick chemical library, the Pharmakon co...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFascin(Homo sapiens (human))
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM350127(5-(2-(benzo[d][1,3]dioxol- 5-yl)-2-oxoethyl)-1-(S,...)
Affinity DataIC50:  3.70E+3nMAssay Description:A high throughput assay was developed to screen for fascin specific inhibitors. Purified polymerized F-actin with or without fascin were mixed and in...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFascin(Homo sapiens (human))
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM350127(5-(2-(benzo[d][1,3]dioxol- 5-yl)-2-oxoethyl)-1-(S,...)
Affinity DataIC50:  3.70E+3nMAssay Description:About 150,000 compounds were screened. These chemical compounds were from the LOPAC 1280 collection, the Prestwick chemical library, the Pharmakon co...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFascin(Homo sapiens (human))
Cruk Beatson Institute

Curated by ChEMBL
LigandPNGBDBM50526235(CHEMBL4516481)
Affinity DataIC50:  3.80E+3nMAssay Description:Inhibition of human (His8)2-tagged fascin (1 to 493 residues) expressed in Escherichia coli BL21(DE3) pLysS assessed as reduction in F-actin bundling...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
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