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Found 187 of ic50 for UniProtKB: A0A024RD33
TargetVascular endothelial growth factor A(Homo sapiens (Human))
University Of Florida

Curated by ChEMBL
LigandPNGBDBM50003017(CHEMBL3234202)
Affinity DataIC50:  0.120nMAssay Description:Inhibition of VEGF-A production in human HCT116 cells after 12 hrs by alphaLISA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor A(Homo sapiens (Human))
University Of Florida

Curated by ChEMBL
LigandPNGBDBM50002930(CHEMBL3234200)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of VEGF-A production in human HCT116 cells after 12 hrs by alphaLISA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor A(Homo sapiens (Human))
University Of Florida

Curated by ChEMBL
LigandPNGBDBM50002918(Apratoxin S4)
Affinity DataIC50:  0.320nMAssay Description:Inhibition of VEGF-A production in human HCT116 cells after 12 hrs by alphaLISA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor A(Homo sapiens (Human))
University Of Florida

Curated by ChEMBL
LigandPNGBDBM50002932(CHEMBL3234201)
Affinity DataIC50:  0.470nMAssay Description:Inhibition of VEGF-A production in human HCT116 cells after 12 hrs by alphaLISA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor A(Homo sapiens (Human))
University Of Florida

Curated by ChEMBL
LigandPNGBDBM282581(4-Bromo-5-(3-chloro-5-fluorophenoxy)-2,2-difluoro-...)
Affinity DataIC50:  2nMpH: 7.5Assay Description:The total assay volume was about 100 μL in the following configuration: 2-μL compound in DMSO, 88 μL buffer with protein and probe and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVascular endothelial growth factor A(Homo sapiens (Human))
University Of Florida

Curated by ChEMBL
LigandPNGBDBM282713((R)-4-Bromo-5-(3-chloro-5-fluoro-phenoxy)-2,2- dif...)
Affinity DataIC50: <5nMpH: 7.5Assay Description:The total assay volume was about 100 μL in the following configuration: 2-μL compound in DMSO, 88 μL buffer with protein and probe and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVascular endothelial growth factor A(Homo sapiens (Human))
University Of Florida

Curated by ChEMBL
LigandPNGBDBM282572((R)-3-((4-(difluoromethyl)-2,2-difluoro-3-hydroxy-...)
Affinity DataIC50: <5nMpH: 7.5Assay Description:The total assay volume was about 100 μL in the following configuration: 2-μL compound in DMSO, 88 μL buffer with protein and probe and...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetVascular endothelial growth factor A(Homo sapiens (Human))
University Of Florida

Curated by ChEMBL
LigandPNGBDBM282702((R)-3-((4-(Difluoromethyl)-2,2-difluoro-3-hydroxy-...)
Affinity DataIC50: <5nMpH: 7.5Assay Description:The total assay volume was about 100 μL in the following configuration: 2-μL compound in DMSO, 88 μL buffer with protein and probe and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVascular endothelial growth factor A(Homo sapiens (Human))
University Of Florida

Curated by ChEMBL
LigandPNGBDBM282682(3-((3-Amino-4-(difluoromethyl)-2,2-difluoro-1,1- d...)
Affinity DataIC50: <5nMpH: 7.5Assay Description:The total assay volume was about 100 μL in the following configuration: 2-μL compound in DMSO, 88 μL buffer with protein and probe and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVascular endothelial growth factor A(Homo sapiens (Human))
University Of Florida

Curated by ChEMBL
LigandPNGBDBM282761(5-(3-cyano-5-fluoro-phenoxy)-2,2-difluoro-3- hydro...)
Affinity DataIC50: <5nMpH: 7.5Assay Description:The total assay volume was about 100 μL in the following configuration: 2-μL compound in DMSO, 88 μL buffer with protein and probe and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVascular endothelial growth factor A(Homo sapiens (Human))
University Of Florida

Curated by ChEMBL
LigandPNGBDBM282572((R)-3-((4-(difluoromethyl)-2,2-difluoro-3-hydroxy-...)
Affinity DataIC50: <5nMpH: 7.5Assay Description:The total assay volume was about 100 μL in the following configuration: 2-μL compound in DMSO, 88 μL buffer with protein and probe and...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetVascular endothelial growth factor A(Homo sapiens (Human))
University Of Florida

Curated by ChEMBL
LigandPNGBDBM282584(4-Chloro-5-(3-chloro-5-fluorophenoxy)-2,2-difluoro...)
Affinity DataIC50: <5nMpH: 7.5Assay Description:The total assay volume was about 100 μL in the following configuration: 2-μL compound in DMSO, 88 μL buffer with protein and probe and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVascular endothelial growth factor A(Homo sapiens (Human))
University Of Florida

Curated by ChEMBL
LigandPNGBDBM282689(US9884843, Compound 33)
Affinity DataIC50: <5nMpH: 7.5Assay Description:The total assay volume was about 100 μL in the following configuration: 2-μL compound in DMSO, 88 μL buffer with protein and probe and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVascular endothelial growth factor A(Homo sapiens (Human))
University Of Florida

Curated by ChEMBL
LigandPNGBDBM282598(5-(3-Chloro-5-fluorophenoxy)-2,2-difluoro-3- hydro...)
Affinity DataIC50: <5nMpH: 7.5Assay Description:The total assay volume was about 100 μL in the following configuration: 2-μL compound in DMSO, 88 μL buffer with protein and probe and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVascular endothelial growth factor A(Homo sapiens (Human))
University Of Florida

Curated by ChEMBL
LigandPNGBDBM282632(5-(3-Chloro-5-fluorophenoxy)-4-(difluoromethyl)- 2...)
Affinity DataIC50: <5nMpH: 7.5Assay Description:The total assay volume was about 100 μL in the following configuration: 2-μL compound in DMSO, 88 μL buffer with protein and probe and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVascular endothelial growth factor A(Homo sapiens (Human))
University Of Florida

Curated by ChEMBL
LigandPNGBDBM282634(3-Amino-4-(difluoromethyl)-5-(3,5- difluorophenoxy...)
Affinity DataIC50: <5nMpH: 7.5Assay Description:The total assay volume was about 100 μL in the following configuration: 2-μL compound in DMSO, 88 μL buffer with protein and probe and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVascular endothelial growth factor A(Homo sapiens (Human))
University Of Florida

Curated by ChEMBL
LigandPNGBDBM282656(4-(Difluoromethyl)-5-(3,5-difluorophenoxy)-2,2- di...)
Affinity DataIC50: <5nMpH: 7.5Assay Description:The total assay volume was about 100 μL in the following configuration: 2-μL compound in DMSO, 88 μL buffer with protein and probe and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVascular endothelial growth factor A(Homo sapiens (Human))
University Of Florida

Curated by ChEMBL
LigandPNGBDBM282686(US9884843, Compound 30)
Affinity DataIC50: <5nMpH: 7.5Assay Description:The total assay volume was about 100 μL in the following configuration: 2-μL compound in DMSO, 88 μL buffer with protein and probe and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVascular endothelial growth factor A(Homo sapiens (Human))
University Of Florida

Curated by ChEMBL
LigandPNGBDBM282632(5-(3-Chloro-5-fluorophenoxy)-4-(difluoromethyl)- 2...)
Affinity DataIC50: <5nMpH: 7.5Assay Description:The total assay volume was about 100 μL in the following configuration: 2-μL compound in DMSO, 88 μL buffer with protein and probe and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVascular endothelial growth factor A(Homo sapiens (Human))
University Of Florida

Curated by ChEMBL
LigandPNGBDBM25115(3-[(4-bromo-2,6-difluorophenyl)methoxy]-5-({[4-(py...)
Affinity DataIC50:  5.27nMAssay Description:Inhibition of VEGF-stimulated VEGFR-2 autophosphorylation in intact cells.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetVascular endothelial growth factor A(Homo sapiens (Human))
University Of Florida

Curated by ChEMBL
LigandPNGBDBM282564((R)-3-((4-bromo-2,2-difluoro-3-hydroxy-1,1-dioxido...)
Affinity DataIC50:  7nMpH: 7.5Assay Description:The total assay volume was about 100 μL in the following configuration: 2-μL compound in DMSO, 88 μL buffer with protein and probe and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVascular endothelial growth factor A(Homo sapiens (Human))
University Of Florida

Curated by ChEMBL
LigandPNGBDBM282768((3R)-5-(3-cyano-5-fluoro-phenoxy)-2,2- difluoro-3-...)
Affinity DataIC50:  9nMpH: 7.5Assay Description:The total assay volume was about 100 μL in the following configuration: 2-μL compound in DMSO, 88 μL buffer with protein and probe and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVascular endothelial growth factor A(Homo sapiens (Human))
University Of Florida

Curated by ChEMBL
LigandPNGBDBM282750(US9884843, Compound 94)
Affinity DataIC50:  11nMpH: 7.5Assay Description:The total assay volume was about 100 μL in the following configuration: 2-μL compound in DMSO, 88 μL buffer with protein and probe and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVascular endothelial growth factor A(Homo sapiens (Human))
University Of Florida

Curated by ChEMBL
LigandPNGBDBM282741((R)-3-((4-chloro-2,2-difluoro-3-hydroxy-1,1-dioxid...)
Affinity DataIC50:  11nMpH: 7.5Assay Description:The total assay volume was about 100 μL in the following configuration: 2-μL compound in DMSO, 88 μL buffer with protein and probe and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVascular endothelial growth factor A(Homo sapiens (Human))
University Of Florida

Curated by ChEMBL
LigandPNGBDBM282685(3-((4-(Difluoromethyl)-2,2-difluoro-3-hydroxy-1,1-...)
Affinity DataIC50:  14nMpH: 7.5Assay Description:The total assay volume was about 100 μL in the following configuration: 2-μL compound in DMSO, 88 μL buffer with protein and probe and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails US Patent
TargetVascular endothelial growth factor A(Homo sapiens (Human))
University Of Florida

Curated by ChEMBL
LigandPNGBDBM282597(US9884843, Compound 13)
Affinity DataIC50:  15nMpH: 7.5Assay Description:The total assay volume was about 100 μL in the following configuration: 2-μL compound in DMSO, 88 μL buffer with protein and probe and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVascular endothelial growth factor A(Homo sapiens (Human))
University Of Florida

Curated by ChEMBL
LigandPNGBDBM282740((R)-3-((4-bromo-2,2-difluoro-3-hydroxy-1,1-dioxido...)
Affinity DataIC50:  17nMpH: 7.5Assay Description:The total assay volume was about 100 μL in the following configuration: 2-μL compound in DMSO, 88 μL buffer with protein and probe and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVascular endothelial growth factor A(Homo sapiens (Human))
University Of Florida

Curated by ChEMBL
LigandPNGBDBM282707(US9884843, Compound 51)
Affinity DataIC50:  20nMpH: 7.5Assay Description:The total assay volume was about 100 μL in the following configuration: 2-μL compound in DMSO, 88 μL buffer with protein and probe and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVascular endothelial growth factor A(Homo sapiens (Human))
University Of Florida

Curated by ChEMBL
LigandPNGBDBM282746((R)-4-(Difluoromethyl)-5-(3,4-difluorophenoxy)-2,2...)
Affinity DataIC50:  24nMpH: 7.5Assay Description:The total assay volume was about 100 μL in the following configuration: 2-μL compound in DMSO, 88 μL buffer with protein and probe and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVascular endothelial growth factor A(Homo sapiens (Human))
University Of Florida

Curated by ChEMBL
LigandPNGBDBM282708(4-(Difluoromethyl)-5-(3,5-difluorophenoxy)-2,2- di...)
Affinity DataIC50:  29nMpH: 7.5Assay Description:The total assay volume was about 100 μL in the following configuration: 2-μL compound in DMSO, 88 μL buffer with protein and probe and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVascular endothelial growth factor A(Homo sapiens (Human))
University Of Florida

Curated by ChEMBL
LigandPNGBDBM282711((R)-3-Amino-4-(difluoromethyl)-5-(3,5- difluorophe...)
Affinity DataIC50:  33nMpH: 7.5Assay Description:The total assay volume was about 100 μL in the following configuration: 2-μL compound in DMSO, 88 μL buffer with protein and probe and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVascular endothelial growth factor A(Homo sapiens (Human))
University Of Florida

Curated by ChEMBL
LigandPNGBDBM282745((R)-3-((4-(difluoromethyl)-2,2-difluoro-3-hydroxy-...)
Affinity DataIC50:  34nMpH: 7.5Assay Description:The total assay volume was about 100 μL in the following configuration: 2-μL compound in DMSO, 88 μL buffer with protein and probe and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVascular endothelial growth factor A(Homo sapiens (Human))
University Of Florida

Curated by ChEMBL
LigandPNGBDBM282685(3-((4-(Difluoromethyl)-2,2-difluoro-3-hydroxy-1,1-...)
Affinity DataIC50:  34nMpH: 7.5Assay Description:The total assay volume was about 100 μL in the following configuration: 2-μL compound in DMSO, 88 μL buffer with protein and probe and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails US Patent
TargetVascular endothelial growth factor A(Homo sapiens (Human))
University Of Florida

Curated by ChEMBL
LigandPNGBDBM282756(5-(3,5-Difluorophenoxy)-2,2-difluoro-3- hydroxy-3-...)
Affinity DataIC50:  41nMpH: 7.5Assay Description:The total assay volume was about 100 μL in the following configuration: 2-μL compound in DMSO, 88 μL buffer with protein and probe and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVascular endothelial growth factor A(Homo sapiens (Human))
University Of Florida

Curated by ChEMBL
LigandPNGBDBM282583(US9884843, Compound 10)
Affinity DataIC50:  45nMpH: 7.5Assay Description:The total assay volume was about 100 μL in the following configuration: 2-μL compound in DMSO, 88 μL buffer with protein and probe and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVascular endothelial growth factor A(Homo sapiens (Human))
University Of Florida

Curated by ChEMBL
LigandPNGBDBM282753(US9884843, Compound 97)
Affinity DataIC50:  46nMpH: 7.5Assay Description:The total assay volume was about 100 μL in the following configuration: 2-μL compound in DMSO, 88 μL buffer with protein and probe and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVascular endothelial growth factor A(Homo sapiens (Human))
University Of Florida

Curated by ChEMBL
LigandPNGBDBM282570((3R)-5-(3-chloro-5-fluoro-phenoxy)-3-hydroxy-1,1- ...)
Affinity DataIC50:  47nMpH: 7.5Assay Description:The total assay volume was about 100 μL in the following configuration: 2-μL compound in DMSO, 88 μL buffer with protein and probe and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVascular endothelial growth factor A(Homo sapiens (Human))
University Of Florida

Curated by ChEMBL
LigandPNGBDBM282736(US9884843, Compound 80)
Affinity DataIC50:  57nMpH: 7.5Assay Description:The total assay volume was about 100 μL in the following configuration: 2-μL compound in DMSO, 88 μL buffer with protein and probe and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVascular endothelial growth factor A(Homo sapiens (Human))
University Of Florida

Curated by ChEMBL
LigandPNGBDBM282719(3-((4-Ethynyl-2,2-difluoro-3-hydroxy-1,1-dioxido- ...)
Affinity DataIC50:  59nMpH: 7.5Assay Description:The total assay volume was about 100 μL in the following configuration: 2-μL compound in DMSO, 88 μL buffer with protein and probe and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVascular endothelial growth factor A(Homo sapiens (Human))
University Of Florida

Curated by ChEMBL
LigandPNGBDBM282708(4-(Difluoromethyl)-5-(3,5-difluorophenoxy)-2,2- di...)
Affinity DataIC50:  59nMpH: 7.5Assay Description:The total assay volume was about 100 μL in the following configuration: 2-μL compound in DMSO, 88 μL buffer with protein and probe and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVascular endothelial growth factor A(Homo sapiens (Human))
University Of Florida

Curated by ChEMBL
LigandPNGBDBM282715(US9884843, Compound 59)
Affinity DataIC50:  60nMpH: 7.5Assay Description:The total assay volume was about 100 μL in the following configuration: 2-μL compound in DMSO, 88 μL buffer with protein and probe and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVascular endothelial growth factor A(Homo sapiens (Human))
University Of Florida

Curated by ChEMBL
LigandPNGBDBM282578(US9884843, Compound 7)
Affinity DataIC50:  61nMpH: 7.5Assay Description:The total assay volume was about 100 μL in the following configuration: 2-μL compound in DMSO, 88 μL buffer with protein and probe and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVascular endothelial growth factor A(Homo sapiens (Human))
University Of Florida

Curated by ChEMBL
LigandPNGBDBM282772((3R)-4-bromo-5-(3-bromo-5-fluoro-phenoxy)- 2,2-dif...)
Affinity DataIC50:  63nMpH: 7.5Assay Description:The total assay volume was about 100 μL in the following configuration: 2-μL compound in DMSO, 88 μL buffer with protein and probe and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVascular endothelial growth factor A(Homo sapiens (Human))
University Of Florida

Curated by ChEMBL
LigandPNGBDBM282737(US9884843, Compound 81)
Affinity DataIC50:  67nMpH: 7.5Assay Description:The total assay volume was about 100 μL in the following configuration: 2-μL compound in DMSO, 88 μL buffer with protein and probe and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVascular endothelial growth factor A(Homo sapiens (Human))
University Of Florida

Curated by ChEMBL
LigandPNGBDBM282697((R)-3-((3-Amino-4-(difluoromethyl)-2,2-difluoro-1,...)
Affinity DataIC50:  69nMpH: 7.5Assay Description:The total assay volume was about 100 μL in the following configuration: 2-μL compound in DMSO, 88 μL buffer with protein and probe and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVascular endothelial growth factor A(Homo sapiens (Human))
University Of Florida

Curated by ChEMBL
LigandPNGBDBM282747(US9884843, Compound 91)
Affinity DataIC50:  72nMpH: 7.5Assay Description:The total assay volume was about 100 μL in the following configuration: 2-μL compound in DMSO, 88 μL buffer with protein and probe and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVascular endothelial growth factor A(Homo sapiens (Human))
University Of Florida

Curated by ChEMBL
LigandPNGBDBM282677(US9884843, Compound 24)
Affinity DataIC50:  77nMpH: 7.5Assay Description:The total assay volume was about 100 μL in the following configuration: 2-μL compound in DMSO, 88 μL buffer with protein and probe and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVascular endothelial growth factor A(Homo sapiens (Human))
University Of Florida

Curated by ChEMBL
LigandPNGBDBM282754(4-Bromo-5-(3,5-difluorophenoxy)-2,2- difluoro-3-hy...)
Affinity DataIC50:  83nMpH: 7.5Assay Description:The total assay volume was about 100 μL in the following configuration: 2-μL compound in DMSO, 88 μL buffer with protein and probe and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVascular endothelial growth factor A(Homo sapiens (Human))
University Of Florida

Curated by ChEMBL
LigandPNGBDBM282698(3-((2,2-Difluoro-4-(fluoromethyl)-3-hydroxy-1,1- d...)
Affinity DataIC50:  86nMpH: 7.5Assay Description:The total assay volume was about 100 μL in the following configuration: 2-μL compound in DMSO, 88 μL buffer with protein and probe and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVascular endothelial growth factor A(Homo sapiens (Human))
University Of Florida

Curated by ChEMBL
LigandPNGBDBM282599(US9884843, Compound 15)
Affinity DataIC50:  100nMpH: 7.5Assay Description:The total assay volume was about 100 μL in the following configuration: 2-μL compound in DMSO, 88 μL buffer with protein and probe and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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