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TargetBromodomain-containing protein 4 [44-168](Human)
Jubilant Biosys

US Patent
LigandPNGBDBM50260101(CHEMBL4068487 | US10689390, Compound 38 | US113193...)
Affinity DataIC50: 0.5nMAssay Description:Compounds were diluted by step-down dilution method (final concentration of DMSO was 1%) and added to the wells of a 384 well opti plate at desired c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
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TargetBromodomain-containing protein 4 [44-168](Human)
Jubilant Biosys

US Patent
LigandPNGBDBM684552(US12030880, Example 18)
Affinity DataIC50: 0.640nMAssay Description:In the present application, IC50 values of the compounds in inhibiting BRD4 (BD1) enzyme binding reaction were determined by homogeneous time resolve...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2024
Entry Details
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TargetBromodomain-containing protein 4 [44-168](Human)
Jubilant Biosys

US Patent
LigandPNGBDBM205431((6S+2S)-PEG1 (7))
Affinity DataIC50: 0.758nMpH: 7.5 T: 2°CAssay Description:Assays were performed with minor modifications from the manufacturer's protocol (PerkinElmer, USA). All reagents were diluted in 50 mM HEPES, 150...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2016
Entry Details Article
PubMed
TargetBromodomain-containing protein 4 [44-168](Human)
Jubilant Biosys

US Patent
LigandPNGBDBM205435((6S+2S)-PEG7 (11))
Affinity DataIC50: 0.789nMpH: 7.5 T: 2°CAssay Description:Assays were performed with minor modifications from the manufacturer's protocol (PerkinElmer, USA). All reagents were diluted in 50 mM HEPES, 150...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2016
Entry Details Article
PubMed
TargetBromodomain-containing protein 4 [44-168](Human)
Jubilant Biosys

US Patent
LigandPNGBDBM684529(US12030880, Example 4)
Affinity DataIC50: 0.930nMAssay Description:In the present application, IC50 values of the compounds in inhibiting BRD4 (BD1) enzyme binding reaction were determined by homogeneous time resolve...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2024
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [44-168](Human)
Jubilant Biosys

US Patent
LigandPNGBDBM209487(US9266891, III-28 | US10328074, Example III-28 | U...)
Affinity DataIC50: 1nMAssay Description:Compounds are diluted in serial dilution 1:5 in assay buffer from 10 mM stock in DMSO (100 μM start concentration) in white OptiPlate-384 (Perki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2022
Entry Details
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TargetBromodomain-containing protein 4 [44-168](Human)
Jubilant Biosys

US Patent
LigandPNGBDBM448073(US10689390, Compound 23 | US11319326, Compound 23)
Affinity DataIC50: 1nMAssay Description:Compounds were diluted by step-down dilution method (final concentration of DMSO was 1%) and added to the wells of a 384 well opti plate at desired c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
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TargetBromodomain-containing protein 4 [44-168](Human)
Jubilant Biosys

US Patent
LigandPNGBDBM205456((2S+2S)-PEG1 (5))
Affinity DataIC50: 1.17nMpH: 7.5 T: 2°CAssay Description:Assays were performed with minor modifications from the manufacturer's protocol (PerkinElmer, USA). All reagents were diluted in 50 mM HEPES, 150...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2016
Entry Details Article
PubMed
TargetBromodomain-containing protein 4 [44-168](Human)
Jubilant Biosys

US Patent
LigandPNGBDBM205432((6S+2S)-PEG2 (8))
Affinity DataIC50: 1.28nMpH: 7.5 T: 2°CAssay Description:Assays were performed with minor modifications from the manufacturer's protocol (PerkinElmer, USA). All reagents were diluted in 50 mM HEPES, 150...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2016
Entry Details Article
PubMed
TargetBromodomain-containing protein 4 [44-168](Human)
Jubilant Biosys

US Patent
LigandPNGBDBM684521(US12030880, Example 2)
Affinity DataIC50: 1.40nMAssay Description:In the present application, IC50 values of the compounds in inhibiting BRD4 (BD1) enzyme binding reaction were determined by homogeneous time resolve...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2024
Entry Details
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TargetBromodomain-containing protein 4 [44-168](Human)
Jubilant Biosys

US Patent
LigandPNGBDBM448074(US10689390, Compound 25 | US11319326, Compound 25)
Affinity DataIC50: 1.60nMAssay Description:Compounds were diluted by step-down dilution method (final concentration of DMSO was 1%) and added to the wells of a 384 well opti plate at desired c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
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TargetBromodomain-containing protein 4 [44-168](Human)
Jubilant Biosys

US Patent
LigandPNGBDBM50260078(CHEMBL4095826 | US10689390, Compound 26 | US113193...)
Affinity DataIC50: 2nMAssay Description:Compounds were diluted by step-down dilution method (final concentration of DMSO was 1%) and added to the wells of a 384 well opti plate at desired c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
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TargetBromodomain-containing protein 4 [44-168](Human)
Jubilant Biosys

US Patent
LigandPNGBDBM205433((6S+2S)-PEG3 (9))
Affinity DataIC50: 2.25nMpH: 7.5 T: 2°CAssay Description:Assays were performed with minor modifications from the manufacturer's protocol (PerkinElmer, USA). All reagents were diluted in 50 mM HEPES, 150...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2016
Entry Details Article
PubMed
TargetBromodomain-containing protein 4 [44-168](Human)
Jubilant Biosys

US Patent
LigandPNGBDBM684543(US12030880, Example 8)
Affinity DataIC50: 2.40nMAssay Description:In the present application, IC50 values of the compounds in inhibiting BRD4 (BD1) enzyme binding reaction were determined by homogeneous time resolve...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2024
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [44-168](Human)
Jubilant Biosys

US Patent
LigandPNGBDBM205434((6S+2S)-PEG4 (10))
Affinity DataIC50: 2.95nMpH: 7.5 T: 2°CAssay Description:Assays were performed with minor modifications from the manufacturer's protocol (PerkinElmer, USA). All reagents were diluted in 50 mM HEPES, 150...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2016
Entry Details Article
PubMed
TargetBromodomain-containing protein 4 [44-168](Human)
Jubilant Biosys

US Patent
LigandPNGBDBM242688(US9422290, I-1)
Affinity DataIC50: 3nMAssay Description:Compounds are diluted in serial dilution 1:5 in assay buffer from 10 mM stock in DMSO (100 μM start concentration) in white OptiPlate-384 (Perki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2017
Entry Details
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TargetBromodomain-containing protein 4 [44-168](Human)
Jubilant Biosys

US Patent
LigandPNGBDBM242696(US9422290, II-3)
Affinity DataIC50: 3nMAssay Description:Compounds are diluted in serial dilution 1:5 in assay buffer from 10 mM stock in DMSO (100 μM start concentration) in white OptiPlate-384 (Perki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2017
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [44-168](Human)
Jubilant Biosys

US Patent
LigandPNGBDBM242702(US9422290, II-9)
Affinity DataIC50: 3nMAssay Description:Compounds are diluted in serial dilution 1:5 in assay buffer from 10 mM stock in DMSO (100 μM start concentration) in white OptiPlate-384 (Perki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2017
Entry Details
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TargetBromodomain-containing protein 4 [44-168](Human)
Jubilant Biosys

US Patent
LigandPNGBDBM242713(US9422290, III-2)
Affinity DataIC50: 3nMAssay Description:Compounds are diluted in serial dilution 1:5 in assay buffer from 10 mM stock in DMSO (100 μM start concentration) in white OptiPlate-384 (Perki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2017
Entry Details
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TargetBromodomain-containing protein 4 [44-168](Human)
Jubilant Biosys

US Patent
LigandPNGBDBM242714(US9422290, III-3)
Affinity DataIC50: 3nMAssay Description:Compounds are diluted in serial dilution 1:5 in assay buffer from 10 mM stock in DMSO (100 μM start concentration) in white OptiPlate-384 (Perki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2017
Entry Details
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TargetBromodomain-containing protein 4 [44-168](Human)
Jubilant Biosys

US Patent
LigandPNGBDBM209474(US9266891, III-15 | US10328074, Example III-15 | U...)
Affinity DataIC50: 3nMAssay Description:Compounds are diluted in serial dilution 1:5 in assay buffer from 10 mM stock in DMSO (100 μM start concentration) in white OptiPlate-384 (Perki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2022
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [44-168](Human)
Jubilant Biosys

US Patent
LigandPNGBDBM209481(US9266891, III-22 | US10328074, Example III-22 | U...)
Affinity DataIC50: 3nMAssay Description:Compounds are diluted in serial dilution 1:5 in assay buffer from 10 mM stock in DMSO (100 μM start concentration) in white OptiPlate-384 (Perki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2022
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [44-168](Human)
Jubilant Biosys

US Patent
LigandPNGBDBM209482(US9266891, III-23 | US10328074, Example III-23 | U...)
Affinity DataIC50: 3nMAssay Description:Compounds are diluted in serial dilution 1:5 in assay buffer from 10 mM stock in DMSO (100 μM start concentration) in white OptiPlate-384 (Perki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2022
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [44-168](Human)
Jubilant Biosys

US Patent
LigandPNGBDBM50260080(CHEMBL4088097 | US10689390, Compound 14 | US113193...)
Affinity DataIC50: 3nMAssay Description:Compounds were diluted by step-down dilution method (final concentration of DMSO was 1%) and added to the wells of a 384 well opti plate at desired c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [44-168](Human)
Jubilant Biosys

US Patent
LigandPNGBDBM684544(US12030880, Example 9)
Affinity DataIC50: 3nMAssay Description:In the present application, IC50 values of the compounds in inhibiting BRD4 (BD1) enzyme binding reaction were determined by homogeneous time resolve...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2024
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [44-168](Human)
Jubilant Biosys

US Patent
LigandPNGBDBM205430((6S+2S)-PEG0 (6))
Affinity DataIC50: 3.58nMpH: 7.5 T: 2°CAssay Description:Assays were performed with minor modifications from the manufacturer's protocol (PerkinElmer, USA). All reagents were diluted in 50 mM HEPES, 150...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2016
Entry Details Article
PubMed
TargetBromodomain-containing protein 4 [44-168](Human)
Jubilant Biosys

US Patent
LigandPNGBDBM242701(US9422290, II-8)
Affinity DataIC50: 4nMAssay Description:Compounds are diluted in serial dilution 1:5 in assay buffer from 10 mM stock in DMSO (100 μM start concentration) in white OptiPlate-384 (Perki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2017
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [44-168](Human)
Jubilant Biosys

US Patent
LigandPNGBDBM209457(US9266891, II-1 | US10328074, Example II-1 | US110...)
Affinity DataIC50: 4nMAssay Description:Compounds are diluted in serial dilution 1:5 in assay buffer from 10 mM stock in DMSO (100 μM start concentration) in white OptiPlate-384 (Perki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2022
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [44-168](Human)
Jubilant Biosys

US Patent
LigandPNGBDBM209508(US9266891, III-49 | US10328074, Example III-49 | U...)
Affinity DataIC50: 4nMAssay Description:Compounds are diluted in serial dilution 1:5 in assay buffer from 10 mM stock in DMSO (100 μM start concentration) in white OptiPlate-384 (Perki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2022
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [44-168](Human)
Jubilant Biosys

US Patent
LigandPNGBDBM448081(US10689390, Compound 37 | US11319326, Compound 37)
Affinity DataIC50: 4nMAssay Description:Compounds were diluted by step-down dilution method (final concentration of DMSO was 1%) and added to the wells of a 384 well opti plate at desired c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [44-168](Human)
Jubilant Biosys

US Patent
LigandPNGBDBM448083(US10689390, Compound 39 | US11319326, Compound 39)
Affinity DataIC50: 4nMAssay Description:Compounds were diluted by step-down dilution method (final concentration of DMSO was 1%) and added to the wells of a 384 well opti plate at desired c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [44-168](Human)
Jubilant Biosys

US Patent
LigandPNGBDBM684547(US12030880, Example 12)
Affinity DataIC50: 4.10nMAssay Description:In the present application, IC50 values of the compounds in inhibiting BRD4 (BD1) enzyme binding reaction were determined by homogeneous time resolve...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2024
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [44-168](Human)
Jubilant Biosys

US Patent
LigandPNGBDBM448076(US10689390, Compound 27 | US11319326, Compound 27)
Affinity DataIC50: 4.40nMAssay Description:Compounds were diluted by step-down dilution method (final concentration of DMSO was 1%) and added to the wells of a 384 well opti plate at desired c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [44-168](Human)
Jubilant Biosys

US Patent
LigandPNGBDBM684549(US12030880, Example 15)
Affinity DataIC50: 4.5nMAssay Description:In the present application, IC50 values of the compounds in inhibiting BRD4 (BD1) enzyme binding reaction were determined by homogeneous time resolve...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2024
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [44-168](Human)
Jubilant Biosys

US Patent
LigandPNGBDBM684534(US12030880, Example 5)
Affinity DataIC50: 4.80nMAssay Description:In the present application, IC50 values of the compounds in inhibiting BRD4 (BD1) enzyme binding reaction were determined by homogeneous time resolve...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2024
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [44-168](Human)
Jubilant Biosys

US Patent
LigandPNGBDBM209475(US9266891, III-16 | US10328074, Example III-16 | U...)
Affinity DataIC50: 5nMAssay Description:Compounds are diluted in serial dilution 1:5 in assay buffer from 10 mM stock in DMSO (100 μM start concentration) in white OptiPlate-384 (Perki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2022
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [44-168](Human)
Jubilant Biosys

US Patent
LigandPNGBDBM209485(US9266891, III-26 | US10328074, Example III-26 | U...)
Affinity DataIC50: 5nMAssay Description:Compounds are diluted in serial dilution 1:5 in assay buffer from 10 mM stock in DMSO (100 μM start concentration) in white OptiPlate-384 (Perki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2022
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [44-168](Human)
Jubilant Biosys

US Patent
LigandPNGBDBM209509(US9266891, III-50 | US10328074, Example III-50 | U...)
Affinity DataIC50: 5nMAssay Description:Compounds are diluted in serial dilution 1:5 in assay buffer from 10 mM stock in DMSO (100 μM start concentration) in white OptiPlate-384 (Perki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2022
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [44-168](Human)
Jubilant Biosys

US Patent
LigandPNGBDBM205454(2S+IBET-PEG2 (25))
Affinity DataIC50: 5.80nMpH: 7.5 T: 2°CAssay Description:Assays were performed with minor modifications from the manufacturer's protocol (PerkinElmer, USA). All reagents were diluted in 50 mM HEPES, 150...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2016
Entry Details Article
PubMed
TargetBromodomain-containing protein 4 [44-168](Human)
Jubilant Biosys

US Patent
LigandPNGBDBM209460(US9266891, III-1 | US10328074, Example III-1 | US1...)
Affinity DataIC50: 7nMAssay Description:Compounds are diluted in serial dilution 1:5 in assay buffer from 10 mM stock in DMSO (100 μM start concentration) in white OptiPlate-384 (Perki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2022
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [44-168](Human)
Jubilant Biosys

US Patent
LigandPNGBDBM209471(US9266891, III-12 | US10328074, Example III-12 | U...)
Affinity DataIC50: 7nMAssay Description:Compounds are diluted in serial dilution 1:5 in assay buffer from 10 mM stock in DMSO (100 μM start concentration) in white OptiPlate-384 (Perki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2022
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [44-168](Human)
Jubilant Biosys

US Patent
LigandPNGBDBM209491(US9266891, III-32 | US10328074, Example III-32 | U...)
Affinity DataIC50: 7nMAssay Description:Compounds are diluted in serial dilution 1:5 in assay buffer from 10 mM stock in DMSO (100 μM start concentration) in white OptiPlate-384 (Perki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2022
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [44-168](Human)
Jubilant Biosys

US Patent
LigandPNGBDBM684553(US12030880, Example 19)
Affinity DataIC50: 7.30nMAssay Description:In the present application, IC50 values of the compounds in inhibiting BRD4 (BD1) enzyme binding reaction were determined by homogeneous time resolve...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2024
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [44-168](Human)
Jubilant Biosys

US Patent
LigandPNGBDBM684528(US12030880, Example 3)
Affinity DataIC50: 7.70nMAssay Description:In the present application, IC50 values of the compounds in inhibiting BRD4 (BD1) enzyme binding reaction were determined by homogeneous time resolve...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2024
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [44-168](Human)
Jubilant Biosys

US Patent
LigandPNGBDBM215738(US9296748, II-25)
Affinity DataIC50: 8nMAssay Description:Compounds are diluted in serial dilution 1:5 in assay buffer from 10 mM stock in DMSO (100 μM start concentration) in white OptiPlate-384 (Perki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2017
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [44-168](Human)
Jubilant Biosys

US Patent
LigandPNGBDBM242699(US9422290, II-6)
Affinity DataIC50: 8nMAssay Description:Compounds are diluted in serial dilution 1:5 in assay buffer from 10 mM stock in DMSO (100 μM start concentration) in white OptiPlate-384 (Perki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2017
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [44-168](Human)
Jubilant Biosys

US Patent
LigandPNGBDBM242700(US9422290, II-7)
Affinity DataIC50: 8nMAssay Description:Compounds are diluted in serial dilution 1:5 in assay buffer from 10 mM stock in DMSO (100 μM start concentration) in white OptiPlate-384 (Perki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2017
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [44-168](Human)
Jubilant Biosys

US Patent
LigandPNGBDBM209453(US9266891, I-5 | US10328074, Example I-5 | US11077...)
Affinity DataIC50: 8nMAssay Description:Compounds are diluted in serial dilution 1:5 in assay buffer from 10 mM stock in DMSO (100 μM start concentration) in white OptiPlate-384 (Perki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2022
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [44-168](Human)
Jubilant Biosys

US Patent
LigandPNGBDBM209463(US9266891, III-4 | US10328074, Example III-4 | US1...)
Affinity DataIC50: 8nMAssay Description:Compounds are diluted in serial dilution 1:5 in assay buffer from 10 mM stock in DMSO (100 μM start concentration) in white OptiPlate-384 (Perki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2022
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [44-168](Human)
Jubilant Biosys

US Patent
LigandPNGBDBM209480(US9266891, III-21 | US10328074, Example III-21 | U...)
Affinity DataIC50: 8nMAssay Description:Compounds are diluted in serial dilution 1:5 in assay buffer from 10 mM stock in DMSO (100 μM start concentration) in white OptiPlate-384 (Perki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2022
Entry Details
Go to US Patent

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