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TargetD(2) dopamine receptor(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandPNGBDBM319696(US10174011, Example 65 | 6-(2-(4-(2-fluorobenzo[b]...)
Affinity DataIC50: 0.0920nMAssay Description:The D2 receptor agonism activity test (The agonism activity of test compounds on D2 receptor expressing human recombinant D2 receptor in HEK293 cells...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent

TargetD(2) dopamine receptor(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandPNGBDBM50511517(CHEMBL4467483)
Affinity DataIC50: 0.123nMAssay Description:Antagonist activity at D2 long receptor (unknown origin) transfected in human HEK293T cells assessed as increase in cAMP accumulation incubated for 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandPNGBDBM50511517(CHEMBL4467483)
Affinity DataIC50: 0.124nMAssay Description:Antagonist activity at D2 long receptor (unknown origin) transfected in human HEK293T cells assessed as increase in cAMP accumulation incubated for 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataIC50: 0.160nMAssay Description:Antagonist activity at recombinant human D2 receptor expressed in CHOK1 cells assessed as inhibition of quinpirole-induced beta arrestin2 recruitment...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataIC50: 0.160nMAssay Description:Antagonist activity against human D2LR expressed in CHOK1 cells assessed as inhibition of pergolide-induced beta-arrestin translocation by beta-galac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/1/2016
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandPNGBDBM319702(US10174011, Example 77 | 5-(2-(4-(2-fluorobenzo[b]...)
Affinity DataIC50: 0.219nMAssay Description:The D2 receptor agonism activity test (The agonism activity of test compounds on D2 receptor expressing human recombinant D2 receptor in HEK293 cells...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent

TargetD(2) dopamine receptor(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandPNGBDBM319695(US10174011, Example 64 | 7-(2-(4-(2-fluorobenzo[b]...)
Affinity DataIC50: 0.242nMAssay Description:The D2 receptor agonism activity test (The agonism activity of test compounds on D2 receptor expressing human recombinant D2 receptor in HEK293 cells...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent

TargetD(2) dopamine receptor(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandPNGBDBM21397(8-[4-(4-fluorophenyl)-4-oxidanylidene-butyl]-1-phe...)
Affinity DataIC50: 0.25nMAssay Description:Displacement of [3H]Spiperone from human recombinant dopamine D2S receptor expressed in CHO cells after 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandPNGBDBM50417295(CHEMBL1276325)
Affinity DataIC50: 0.288nMAssay Description:Antagonist activity at dopamine D2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Reviva Pharmaceuticals

US Patent
LigandPNGBDBM312156(US9604944, 15a (Example 13) | 6-(4-(4-(2-Methoxyph...)
Affinity DataKi:  0.300nM IC50: 0.980nMAssay Description:Receptor Source: Human recombinant expressed in CHO cells Radioligand: [3H]Spiperone (20-60 Ci/mmol) Control Compound: Haloperidol Incubatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
US Patent

TargetD(2) dopamine receptor(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandPNGBDBM50130273(4-[3-(2-chlorophenothiazin-10-yl)propyl]-1-piperaz...)
Affinity DataIC50: 0.300nMT: 2°CAssay Description:Antagonist activity at dopamine D2 receptor (unknown origin) expressed in CHOK1 cells coexpressing Galpha15 assessed as inhibition of agonist-induced...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandPNGBDBM319701(US10174011, Example 74 | 6-(4-(4-(2-fluorobenzo[b]...)
Affinity DataIC50: 0.320nMAssay Description:The D2 receptor agonism activity test (The agonism activity of test compounds on D2 receptor expressing human recombinant D2 receptor in HEK293 cells...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent

TargetD(2) dopamine receptor(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandPNGBDBM319626(US10174011, Example 27 | 5-(2-(4-(benzo[b]thiophen...)
Affinity DataIC50: 0.384nMAssay Description:The D2 receptor agonism activity test (The agonism activity of test compounds on D2 receptor expressing human recombinant D2 receptor in HEK293 cells...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent

TargetD(2) dopamine receptor(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandPNGBDBM319692(US10174011, Example 57 | 7-(2-(4-(2-fluorobenzo[b]...)
Affinity DataIC50: 0.480nMAssay Description:The D2 receptor agonism activity test (The agonism activity of test compounds on D2 receptor expressing human recombinant D2 receptor in HEK293 cells...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent

TargetD(2) dopamine receptor(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandPNGBDBM21397(8-[4-(4-fluorophenyl)-4-oxidanylidene-butyl]-1-phe...)
Affinity DataKi:  0.5nM ΔG°:  -12.9kcal/mole IC50: 2.56nMT: 2°CAssay Description:Different concentrations (10^−5 M-10^−11 M) of the compound of the invention and corresponding isotope receptor ligand as well as recepto...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
US Patent

TargetD(2) dopamine receptor(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandPNGBDBM50417313(CHEMBL1276585)
Affinity DataIC50: 0.501nMAssay Description:Antagonist activity at dopamine D2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandPNGBDBM21397(8-[4-(4-fluorophenyl)-4-oxidanylidene-butyl]-1-phe...)
Affinity DataIC50: 0.590nMAssay Description:Antagonist activity at human D2 receptor stably expressed in CHO-K1 cells assessed as inhibition of forskolin stimulated cAMP production incubated fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetD(2) dopamine receptor(Human)
Reviva Pharmaceuticals

US Patent
LigandPNGBDBM312188(US9604944, 15b (Example 14) | 6-(4-(4-(2,3-Dichlor...)
Affinity DataKi:  0.610nM IC50: 1.96nMAssay Description:Receptor Source: Human recombinant expressed in CHO cells Radioligand: [3H]Spiperone (20-60 Ci/mmol) Control Compound: Haloperidol Incubatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
US Patent

TargetD(2) dopamine receptor(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandPNGBDBM319700(US10174011, Example 72 | 6-(4-(4-(benzo[b]thiophen...)
Affinity DataIC50: 0.672nMAssay Description:The D2 receptor agonism activity test (The agonism activity of test compounds on D2 receptor expressing human recombinant D2 receptor in HEK293 cells...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent

TargetD(2) dopamine receptor(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandPNGBDBM50026568(N-(1-Ethyl-pyrrolidin-2-ylmethyl)-3-iodo-2,6-dimet...)
Affinity DataIC50: 0.676nMAssay Description:Antagonist activity at dopamine D2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataIC50: 0.700nMAssay Description:Antagonist activity at human dopamine D2 short receptor transiently expressed in HEK293 cells assessed as inhibition of beta-arrestin recruitment aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandPNGBDBM50008735(CHEMBL8514 | BUTACLAMOL,d- | (+)-3-(tert-butyl)-(3...)
Affinity DataIC50: 0.810nMAssay Description:Displacement of [3H]methyl-spiperone from human recombinant D2S receptor in HEK293 cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2019
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandPNGBDBM50417312(CHEMBL1276560)
Affinity DataIC50: 0.912nMAssay Description:Antagonist activity at dopamine D2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandPNGBDBM312156(US9604944, 15a (Example 13) | 6-(4-(4-(2-Methoxyph...)
Affinity DataIC50: 0.980nMAssay Description:Dopamine, D2S: Materials and Methods: Receptor Source: Human recombinant expressed in CHO cells Radioligand: [3H]Spiperone (20-60 Ci/mmol) Control Co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2020
Entry Details
US Patent

TargetD(2) dopamine receptor(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandPNGBDBM50542261(CHEMBL4644391)
Affinity DataIC50: 1nMAssay Description:Antagonist activity at D2 receptor (unknown origin) by HTRF cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandPNGBDBM50001888([3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-...)
Affinity DataIC50: 1nMAssay Description:Antagonist activity against human recombinant dopmaine D2L receptor expressed in CHOK1 cells assessed as reduction in apomorphine-induced increase in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2016
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandPNGBDBM50001888([3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-...)
Affinity DataIC50: 1nMAssay Description:Antagonist activity at human dopamine D2 receptor expressed in CHOK1 cells assessed as inhibition of apomorphine-induced calcium mobilization by radi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2016
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandPNGBDBM319701(US10174011, Example 74 | 6-(4-(4-(2-fluorobenzo[b]...)
Affinity DataIC50: 1.06nMAssay Description:The D2 receptor antagonism activity test (The antagonism activity of test compounds on D2 receptor expressing human recombinant D2 receptor in HEK293...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent

TargetD(2) dopamine receptor(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandPNGBDBM50057761(CHEMBL3322994)
Affinity DataIC50: 1.10nMAssay Description:Antagonist activity against human D2LR expressed in CHO cells assessed as inhibition of dopamine-induced [35S]GTPgammaS binding by dopamine potency s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/1/2016
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandPNGBDBM50417296(CHEMBL1276326)
Affinity DataIC50: 1.10nMAssay Description:Antagonist activity at dopamine D2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandPNGBDBM50208987(CHEMBL3885419)
Affinity DataIC50: 1.10nMAssay Description:Displacement of [3H]methyl-spiperone from human recombinant dopamine D2S receptor expressed in HEK293 cells measured after 60 mins by scintillation c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2018
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandPNGBDBM50008735(CHEMBL8514 | BUTACLAMOL,d- | (+)-3-(tert-butyl)-(3...)
Affinity DataIC50: 1.10nMAssay Description:Displacement of [3H]methylspiperone from human recombinant Dopamine D2S receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2017
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandPNGBDBM319704(US10174011, Example 79 | 5-(2-(4-(2-fluorobenzo[b]...)
Affinity DataIC50: 1.20nMAssay Description:The D2 receptor agonism activity test (The agonism activity of test compounds on D2 receptor expressing human recombinant D2 receptor in HEK293 cells...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent

TargetD(2) dopamine receptor(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandPNGBDBM21397(8-[4-(4-fluorophenyl)-4-oxidanylidene-butyl]-1-phe...)
Affinity DataIC50: 1.20nMAssay Description:Antagonist activity at human D2 receptor stably expressed in CHO-K1 cells assessed as beta arrestin recruitment preincubated for 90 mins by tropix-ga...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetD(2) dopamine receptor(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandPNGBDBM50026045(CHEMBL22242 | 3-Bromo-N-((S)-1-ethyl-pyrrolidin-2-...)
Affinity DataIC50: 1.20nMAssay Description:Antagonist activity at dopamine D2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandPNGBDBM21397(8-[4-(4-fluorophenyl)-4-oxidanylidene-butyl]-1-phe...)
Affinity DataIC50: 1.27nMAssay Description:Displacement of [3H]Spiprone from human dopamine D2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandPNGBDBM50026565(3-Ethyl-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2,6-dime...)
Affinity DataIC50: 1.29nMAssay Description:Antagonist activity at dopamine D2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandPNGBDBM50417297(CHEMBL1276327)
Affinity DataIC50: 1.29nMAssay Description:Antagonist activity at dopamine D2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandPNGBDBM319719(US10174011, Example 101 | 5-(4-(4-(2-fluorobenzo[b...)
Affinity DataIC50: 1.30nMAssay Description:The D2 receptor agonism activity test (The agonism activity of test compounds on D2 receptor expressing human recombinant D2 receptor in HEK293 cells...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent

TargetD(2) dopamine receptor(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandPNGBDBM50366495(CHEMBL1255588 | (+)butaclamol)
Affinity DataIC50: 1.40nMAssay Description:Binding affinity to human dopamine D2S receptor by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandPNGBDBM50417307(CHEMBL1276494)
Affinity DataIC50: 1.41nMAssay Description:Antagonist activity at dopamine D2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandPNGBDBM81790(NSC_2159 | CAS_71675-85-9 | Amisulpride | US101672...)
Affinity DataIC50: 1.5nMAssay Description:The ability of Compound 102 to bind dopamine D2 receptors was measured in a cell-based assay. Dopamine D2 receptor cells were seeded in a half a blac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
US Patent

TargetD(2) dopamine receptor(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandPNGBDBM50542263(CHEMBL4638430)
Affinity DataIC50: 1.5nMAssay Description:Antagonist activity at D2 receptor (unknown origin) by HTRF cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandPNGBDBM81790(NSC_2159 | CAS_71675-85-9 | Amisulpride | US101672...)
Affinity DataIC50: 1.5nMAssay Description:The ability of Compound 102 to bind dopamine D2 receptors was measured in a cell-based assay. Dopamine D2 receptor cells were seeded in a half a blac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2020
Entry Details
US Patent

TargetD(2) dopamine receptor(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandPNGBDBM50417311(CHEMBL1276559)
Affinity DataIC50: 1.51nMAssay Description:Antagonist activity at dopamine D2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandPNGBDBM50417320(CHEMBL1276712)
Affinity DataIC50: 1.70nMAssay Description:Antagonist activity at dopamine D2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandPNGBDBM50443101(Cariprazine | RGH-188 | US20250109139, Compound Ca...)
Affinity DataIC50: 1.70nMAssay Description:Antagonist activity at human dopamine D2 short receptor transiently expressed in HEK293 cells assessed as inhibition of beta-arrestin recruitment aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandPNGBDBM50417335(CHEMBL1276647)
Affinity DataIC50: 1.78nMAssay Description:Antagonist activity at dopamine D2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandPNGBDBM50005118(3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-h...)
Affinity DataIC50: 1.80nMAssay Description:Antagonist activity at C-terminal RLuc8-fused D2 long receptor (unknown origin) transfected in human HEK293T cells co-expressing N-terminal Venus-tag...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandPNGBDBM392076(US10301272, Example 7/9)
Affinity DataIC50: 1.80nMAssay Description:Displacement of [3H]7-OH-DPAT from human recombinant dopamine D2S receptor after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/27/2020
Entry Details Article
PubMed
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