Compile Data Set for Download or QSAR
Report error Found 55 of ec50 data for polymerid = 7150
Target5-hydroxytryptamine receptor 2C(Rat)
Alcon Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50014945BDBM50014945(alpha-methyl-5-HT | alpha-methyl-5-hydroxytryptami...)
Affinity DataEC50:  1.80nMAssay Description:Activity against recombinant rat 5HT2C mediated intracellular calcium mobilization by FLIPR in SR3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
Alcon Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 10755BDBM10755([3H]-5-HT | 5-Hydroxy Tryptamine | CHEMBL535832 | ...)
Affinity DataEC50:  2.80nMAssay Description:Activity against recombinant rat 5HT2C mediated intracellular calcium mobilization by FLIPR in SR3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
Alcon Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50014219BDBM50014219(CHEMBL31115 | 5-methoxy-alpha-methyltryptamine | 2...)
Affinity DataEC50:  3.10nMAssay Description:Activity against recombinant rat 5HT2C mediated intracellular calcium mobilization by FLIPR in SR3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
Alcon Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50180251BDBM50180251(1-((S)-2-aminopropyl)-1H-indazol-6-ol | CHEMBL3713...)
Affinity DataEC50:  3.70nMAssay Description:Activity against recombinant rat 5HT2C mediated intracellular calcium mobilization by FLIPR in SR3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
Alcon Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50180257BDBM50180257(1-(2-aminoethyl)-1H-indazol-6-ol | CHEMBL199385)
Affinity DataEC50:  4.5nMAssay Description:Activity against recombinant rat 5HT2C mediated intracellular calcium mobilization by FLIPR in SR3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
Alcon Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50210083BDBM50210083([8-((R)-2-amino-propyl)-2,3,6,7-tetrahydro-benzo[1...)
Affinity DataEC50:  4.5nMAssay Description:Agonist activity at 5HT2C receptor expressed in rat SR3T3 cells assessed as intracellular calcium mobilization relative to 5HTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
Alcon Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50180255BDBM50180255(1-((S)-2-aminopropyl)-7-chloro-1H-indazol-6-ol | C...)
Affinity DataEC50:  4.90nMAssay Description:Activity against recombinant rat 5HT2C mediated intracellular calcium mobilization by FLIPR in SR3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
Alcon Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50180258BDBM50180258(1-((S)-2-aminopropyl)-7-fluoro-1H-indazol-6-ol | C...)
Affinity DataEC50:  5.5nMAssay Description:Activity against recombinant rat 5HT2C mediated intracellular calcium mobilization by FLIPR in SR3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
Alcon Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50180252BDBM50180252((S)-2-(6-methoxyindazol-1-yl)-1-methylethylamine |...)
Affinity DataEC50:  6.70nMAssay Description:Activity against recombinant rat 5HT2C mediated intracellular calcium mobilization by FLIPR in SR3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
Alcon Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50180253BDBM50180253(1-((S)-2-aminopropyl)-7-methyl-1H-indazol-6-ol | C...)
Affinity DataEC50:  7.30nMAssay Description:Activity against recombinant rat 5HT2C mediated intracellular calcium mobilization by FLIPR in SR3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
Alcon Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50210079BDBM50210079((R)-2-[8-(2-methoxy-ethoxymethyl)-2,3,6,7-tetrahyd...)
Affinity DataEC50:  8.60nMAssay Description:Agonist activity at 5HT2C receptor expressed in rat SR3T3 cells assessed as intracellular calcium mobilization relative to 5HTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
Alcon Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50210078BDBM50210078((R)-2-(8-methoxymethyl-2,3,6,7-tetrahydro-benzo[1,...)
Affinity DataEC50:  12.6nMAssay Description:Agonist activity at 5HT2C receptor expressed in rat SR3T3 cells assessed as intracellular calcium mobilization relative to 5HTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
Alcon Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50133231BDBM50133231((R)-2-(4-iodo-2,5-dimethoxyphenyl)-1-methylethylam...)
Affinity DataEC50:  30nMAssay Description:Activity against recombinant rat 5HT2C mediated intracellular calcium mobilization by FLIPR in SR3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
Alcon Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50133231BDBM50133231((R)-2-(4-iodo-2,5-dimethoxyphenyl)-1-methylethylam...)
Affinity DataEC50:  30.2nMAssay Description:Agonist activity at 5HT2C receptor expressed in rat SR3T3 cells assessed as intracellular calcium mobilization relative to 5HTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
Alcon Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50210081BDBM50210081((1R,2R)-2-amino-1-(8-bromo-2,3,6,7-tetrahydro-benz...)
Affinity DataEC50:  39nMAssay Description:Agonist activity at 5HT2C receptor expressed in rat SR3T3 cells assessed as intracellular calcium mobilization relative to 5HTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
Alcon Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50309343BDBM50309343(8-methyl-2,3,4,5,5a,6-hexahydro-[1,4]diazepino[1,7...)
Affinity DataEC50:  61nMAssay Description:Agonist activity at 5HT2C receptor in rat fundusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
Alcon Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 30707BDBM30707(3-(2-DIMETHYLAMINOETHYL)-5-METHOXYINDOLE | CHEMBL7...)
Affinity DataEC50:  78nMAssay Description:Activity against recombinant rat 5HT2C mediated intracellular calcium mobilization by FLIPR in SR3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
Alcon Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50210084BDBM50210084((R)-1-methyl-2-[8-(3-methyl-[1,2,4]oxadiazol-5-ylm...)
Affinity DataEC50:  82nMAssay Description:Agonist activity at 5HT2C receptor expressed in rat SR3T3 cells assessed as intracellular calcium mobilization relative to 5HTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
Alcon Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50180256BDBM50180256(1-((R)-2-aminopropyl)-1H-indazol-6-ol | CHEMBL4373...)
Affinity DataEC50:  87nMAssay Description:Activity against recombinant rat 5HT2C mediated intracellular calcium mobilization by FLIPR in SR3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
Alcon Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50471324BDBM50471324(CHEMBL318639)
Affinity DataEC50:  100nMAssay Description:Efficacy (pEC50) was evaluated for 5-HT2C receptor-mediated stimulation of IP3 formation in vitro in choroid plexus of the ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
Alcon Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50471319BDBM50471319(CHEMBL2115252)
Affinity DataEC50:  126nMAssay Description:Efficacy (pEC50) was evaluated for 5-HT2C receptor-mediated stimulation of IP3 formation in vitro in choroid plexus of the ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
Alcon Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50025197BDBM50025197(CHEMBL96816)
Affinity DataEC50:  158nMAssay Description:Efficacy (pEC50) was evaluated for 5-HT2C receptor-mediated stimulation of IP3 formation in vitro in choroid plexus of the ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
Alcon Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 28582BDBM28582([125I]2,5-dimethoxy-4-iodoamphetamine | CHEMBL6616...)
Affinity DataEC50:  178nMAssay Description:Agonist activity at rat 5-HT2C receptor expressed in African clawed frog oocytes assessed as increase in current amplitudeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2019
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
Alcon Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50108306BDBM50108306((S)-2-(5,6-Difluoro-indol-1-yl)-1-methyl-ethylamin...)
Affinity DataEC50:  200nMAssay Description:Efficacy (pEC50) was evaluated for 5-HT2C receptor-mediated stimulation of IP3 formation in vitro in choroid plexus of the ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
Alcon Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50144841BDBM50144841((S)-1-(6-chloro-5-fluoro-1H-indol-1-yl)propan-2-am...)
Affinity DataEC50:  200nMAssay Description:Efficacy (pEC50) was evaluated for 5-HT2C receptor-mediated stimulation of IP3 formation in vitro in choroid plexus of the ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
Alcon Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 85863BDBM85863(CAS_170493-63-7 | NSC_3045228 | Ro 600332)
Affinity DataEC50:  200nMAssay Description:Efficacy (pEC50) was evaluated for 5-HT2C receptor-mediated stimulation of IP3 formation in vitro in choroid plexus of the ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
Alcon Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50471322BDBM50471322(CHEMBL94272)
Affinity DataEC50:  200nMAssay Description:Efficacy (pEC50) was evaluated for 5-HT2C receptor-mediated stimulation of IP3 formation in vitro in choroid plexus of the ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
Alcon Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50471326BDBM50471326(CHEMBL2114265)
Affinity DataEC50:  251nMAssay Description:Efficacy (pEC50) was evaluated for 5-HT2C receptor-mediated stimulation of IP3 formation in vitro in choroid plexus of the ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
Alcon Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50471318BDBM50471318(CHEMBL2114266)
Affinity DataEC50:  316nMAssay Description:Efficacy (pEC50) was evaluated for 5-HT2C receptor-mediated stimulation of IP3 formation in vitro in choroid plexus of the ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
Alcon Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50471312BDBM50471312(CHEMBL313856)
Affinity DataEC50:  398nMAssay Description:Efficacy (pEC50) was evaluated for 5-HT2C receptor-mediated stimulation of IP3 formation in vitro in choroid plexus of the ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
Alcon Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50471314BDBM50471314(CHEMBL414163)
Affinity DataEC50:  398nMAssay Description:Efficacy (pEC50) was evaluated for 5-HT2C receptor-mediated stimulation of IP3 formation in vitro in choroid plexus of the ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
Alcon Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50471332BDBM50471332(CHEMBL96312)
Affinity DataEC50:  501nMAssay Description:Efficacy (pEC50) was evaluated for 5-HT2C receptor-mediated stimulation of IP3 formation in vitro in choroid plexus of the ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
Alcon Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50471328BDBM50471328(CHEMBL92656)
Affinity DataEC50:  631nMAssay Description:Efficacy (pEC50) was evaluated for 5-HT2C receptor-mediated stimulation of IP3 formation in vitro in choroid plexus of the ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
Alcon Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50471325BDBM50471325(CHEMBL93154)
Affinity DataEC50:  631nMAssay Description:Efficacy (pEC50) was evaluated for 5-HT2C receptor-mediated stimulation of IP3 formation in vitro in choroid plexus of the ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
Alcon Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50210085BDBM50210085((R)-1-methyl-2-[8-(3-methyl-[1,2,4]oxadiazol-5-ylm...)
Affinity DataEC50:  689nMAssay Description:Agonist activity at 5HT2C receptor expressed in rat SR3T3 cells assessed as intracellular calcium mobilization relative to 5HTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
Alcon Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50471329BDBM50471329(CHEMBL2115254)
Affinity DataEC50:  794nMAssay Description:Efficacy (pEC50) was evaluated for 5-HT2C receptor-mediated stimulation of IP3 formation in vitro in choroid plexus of the ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
Alcon Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50059890BDBM50059890(2-(8-Methoxy-2,3,5,6-tetrahydro-benzo[1,2-b;5,4-b'...)
Affinity DataEC50:  1.00E+3nMAssay Description:Effect on phosphoinositide hydrolysis in NIH 3T3 fibroblast 5-hydroxytryptamine 2C receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
Alcon Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50471313BDBM50471313(CHEMBL92565)
Affinity DataEC50:  1.26E+3nMAssay Description:Efficacy (pEC50) was evaluated for 5-HT2C receptor-mediated stimulation of IP3 formation in vitro in choroid plexus of the ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
Alcon Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50321881BDBM50321881((R,S)-1-(5-fluoro-1H-indol-1-yl)propan-2-amine | 2...)
Affinity DataEC50:  1.59E+3nMAssay Description:Efficacy (pEC50) was evaluated for 5-HT2C receptor-mediated stimulation of IP3 formation in vitro in choroid plexus of the ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
Alcon Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50471320BDBM50471320(CHEMBL273304)
Affinity DataEC50:  2.00E+3nMAssay Description:Efficacy (pEC50) was evaluated for 5-HT2C receptor-mediated stimulation of IP3 formation in vitro in choroid plexus of the ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
Alcon Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50321879BDBM50321879(2-(5-Bromo-indol-1-yl)-1-methyl-ethylamine | (R,S)...)
Affinity DataEC50:  2.00E+3nMAssay Description:Efficacy (pEC50) was evaluated for 5-HT2C receptor-mediated stimulation of IP3 formation in vitro in choroid plexus of the ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
Alcon Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50321880BDBM50321880(2-(5-Chloro-indol-1-yl)-1-methyl-ethylamine | (R,S...)
Affinity DataEC50:  2.00E+3nMAssay Description:Efficacy (pEC50) was evaluated for 5-HT2C receptor-mediated stimulation of IP3 formation in vitro in choroid plexus of the ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
Alcon Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50059892BDBM50059892(2-(6,7-Dimethoxy-2,3-dihydro-benzofuran-4-yl)-ethy...)
Affinity DataEC50:  2.00E+3nMAssay Description:Effect on phosphoinositide hydrolysis in NIH 3T3 fibroblast 5-hydroxytryptamine 2C receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
Alcon Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50059893BDBM50059893(2-(4-Ethoxy-3,5-dimethoxy-phenyl)-ethylamine | CHE...)
Affinity DataEC50:  2.00E+3nMAssay Description:Effect on phosphoinositide hydrolysis in NIH 3T3 fibroblast 5-hydroxytryptamine 2C receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
Alcon Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50471316BDBM50471316(CHEMBL317677)
Affinity DataEC50:  2.51E+3nMAssay Description:Efficacy (pEC50) was evaluated for 5-HT2C receptor-mediated stimulation of IP3 formation in vitro in choroid plexus of the ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
Alcon Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50471321BDBM50471321(CHEMBL91855)
Affinity DataEC50:  2.51E+3nMAssay Description:Efficacy (pEC50) was evaluated for 5-HT2C receptor-mediated stimulation of IP3 formation in vitro in choroid plexus of the ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
Alcon Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50321882BDBM50321882((R,S)-1-(5-methyl-1H-indol-1-yl)propan-2-amine | 1...)
Affinity DataEC50:  2.51E+3nMAssay Description:Efficacy (pEC50) was evaluated for 5-HT2C receptor-mediated stimulation of IP3 formation in vitro in choroid plexus of the ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
Alcon Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50471315BDBM50471315(CHEMBL320145)
Affinity DataEC50:  2.51E+3nMAssay Description:Efficacy (pEC50) was evaluated for 5-HT2C receptor-mediated stimulation of IP3 formation in vitro in choroid plexus of the ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
Alcon Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50298361BDBM50298361((R)-1-(6-chloro-5-fluoro-1H-indol-1-yl)propan-2-am...)
Affinity DataEC50:  3.16E+3nMAssay Description:Efficacy (pEC50) was evaluated for 5-HT2C receptor-mediated stimulation of IP3 formation in vitro in choroid plexus of the ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
Alcon Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50471323BDBM50471323(CHEMBL96876)
Affinity DataEC50:  6.31E+3nMAssay Description:Efficacy (pEC50) was evaluated for 5-HT2C receptor-mediated stimulation of IP3 formation in vitro in choroid plexus of the ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
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