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Found 1759 of ic50 for UniProtKB: P06241
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Indo-Soviet Friendship College Of Pharmacy (Isfcp)

Curated by ChEMBL
LigandPNGBDBM8793(7-[4-(4-methylpiperazin-1-yl)cyclohexyl]-5-(4-phen...)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of Fyn (unknown origin) using Src-family kinase bisamide rhodamine 110 peptide substrate after 1 hr by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Indo-Soviet Friendship College Of Pharmacy (Isfcp)

Curated by ChEMBL
LigandPNGBDBM50322535(3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N...)
Affinity DataIC50:  0.360nMAssay Description:Binding affinity to human FYN using poly[Glu:Tyr] (4:1) as substrate by radiometric hotspot kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Indo-Soviet Friendship College Of Pharmacy (Isfcp)

Curated by ChEMBL
LigandPNGBDBM50142887(1-(tert-butyl)-3-(4-chlorophenyl)-4-aminopyrazolo[...)
Affinity DataIC50:  0.5nMT: 2°CAssay Description:Kinase activity (Src-family kinases, Hck, Lyn, Fyn, and c-Src) and the effect of the molecules were determined by ProFluor Src-Family Kinase Assay Ki...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Indo-Soviet Friendship College Of Pharmacy (Isfcp)

Curated by ChEMBL
LigandPNGBDBM13216(BMS-354825 | CHEMBL1421 | DASATINIB | N-(2-Chloro-...)
Affinity DataIC50: <0.5nMAssay Description:Inhibition of human FYN using poly[Glu,Tyr]4:1 as substrate in presence of [gamma-33P]ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Indo-Soviet Friendship College Of Pharmacy (Isfcp)

Curated by ChEMBL
LigandPNGBDBM13268(BMS-354825 2-Heteroarylamino-thiazole Analog 12m |...)
Affinity DataIC50:  1nMAssay Description:inhibitory activity against Fyn protein kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Indo-Soviet Friendship College Of Pharmacy (Isfcp)

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of human FYN using poly[Glu:Tyr] (4:1) as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Indo-Soviet Friendship College Of Pharmacy (Isfcp)

Curated by ChEMBL
LigandPNGBDBM13216(BMS-354825 | CHEMBL1421 | DASATINIB | N-(2-Chloro-...)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of Fyn A (unknown origin) preincubated for 10 mins followed by substrate addition and measured after 1 hr by ADP-Glo luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Indo-Soviet Friendship College Of Pharmacy (Isfcp)

Curated by ChEMBL
LigandPNGBDBM13216(BMS-354825 | CHEMBL1421 | DASATINIB | N-(2-Chloro-...)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of Fyn A (unknown origin) preincubated for 10 mins followed by substrate addition and measured after 1 hr by ADP-Glo luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Indo-Soviet Friendship College Of Pharmacy (Isfcp)

Curated by ChEMBL
LigandPNGBDBM4552(4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-...)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of FYNMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Indo-Soviet Friendship College Of Pharmacy (Isfcp)

Curated by ChEMBL
LigandPNGBDBM50026679(CHEMBL3335371)
Affinity DataIC50:  2nMAssay Description:Inhibition of [3H]-FPP incorporation into biotin-linked K-ras decapeptide (CVIM) by bovine farnesyltransferaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Indo-Soviet Friendship College Of Pharmacy (Isfcp)

Curated by ChEMBL
LigandPNGBDBM50059889((staurosporine)3-methoxy-2-methyl-4-methylamino-(2...)
Affinity DataIC50:  2nMAssay Description:Inhibition of FynMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Indo-Soviet Friendship College Of Pharmacy (Isfcp)

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  2.10nMAssay Description:Inhibition of human FYN using poly[Glu:Tyr] (4:1) as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Indo-Soviet Friendship College Of Pharmacy (Isfcp)

Curated by ChEMBL
LigandPNGBDBM50184767(CHEMBL3824089 | US10294227, Code 506)
Affinity DataIC50:  2.10nMAssay Description:Inhibition of human FYN using poly[Glu,Tyr]4:1 as substrate in presence of [gamma-33P]ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Indo-Soviet Friendship College Of Pharmacy (Isfcp)

Curated by ChEMBL
LigandPNGBDBM50602863(CHEMBL1997924)
Affinity DataIC50:  2.20nMAssay Description:Inhibition of human Fyn using Cdc2 peptide as substrate incubated for 40 mins in presence of [gamma-33P]-ATP by radiometric scintillation assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Indo-Soviet Friendship College Of Pharmacy (Isfcp)

Curated by ChEMBL
LigandPNGBDBM13216(BMS-354825 | CHEMBL1421 | DASATINIB | N-(2-Chloro-...)
Affinity DataIC50:  2.70nMAssay Description:Inhibition of from NanoLuc-fused Fyn (unknown origin) transfected in HEK293 cells using tracer K4 incubated for 1 hr by NanoBRET assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Indo-Soviet Friendship College Of Pharmacy (Isfcp)

Curated by ChEMBL
LigandPNGBDBM378887(US10266537, Compound 31)
Affinity DataIC50:  3nMAssay Description:The aim of this experiment is to detect the inhibitory activity of the compounds of the present invention against in vitro protein kinases using isot...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Indo-Soviet Friendship College Of Pharmacy (Isfcp)

Curated by ChEMBL
LigandPNGBDBM50131117(2-[2-(2-Hydroxy-ethylamino)-6-methyl-pyrimidin-4-y...)
Affinity DataIC50:  4nMAssay Description:Inhibition of Fyn protein kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Indo-Soviet Friendship College Of Pharmacy (Isfcp)

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  4.40nMAssay Description:Inhibition of FYN (unknown origin) incubated for 1 hr by spectrophotometric analysisMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Indo-Soviet Friendship College Of Pharmacy (Isfcp)

Curated by ChEMBL
LigandPNGBDBM50086441(CHEMBL3426225 | US10266537, Compound 3)
Affinity DataIC50:  5nMAssay Description:Inhibition of human FynMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Indo-Soviet Friendship College Of Pharmacy (Isfcp)

Curated by ChEMBL
LigandPNGBDBM50378568(CHEMBL1163016)
Affinity DataIC50:  5nMAssay Description:Inhibition of FynMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Indo-Soviet Friendship College Of Pharmacy (Isfcp)

Curated by ChEMBL
LigandPNGBDBM50059889((staurosporine)3-methoxy-2-methyl-4-methylamino-(2...)
Affinity DataIC50:  5nMAssay Description:Inhibition of human Fyn expressed in Sf9 cells after 1 min by ELISA in presence of 1 umol/L ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Indo-Soviet Friendship College Of Pharmacy (Isfcp)

Curated by ChEMBL
LigandPNGBDBM473174((3S,4R)-3-((4-amino-3-(4-phenoxyphenyl)-1H-pyrazol...)
Affinity DataIC50: <5nMAssay Description:IC50 Table 13-20: The protocol calls for test compound of the invention to be incubated with kinase, substrate, cofactors, and radio-isotope-labeled ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Indo-Soviet Friendship College Of Pharmacy (Isfcp)

Curated by ChEMBL
LigandPNGBDBM50086441(CHEMBL3426225 | US10266537, Compound 3)
Affinity DataIC50:  5nMAssay Description:The aim of this experiment is to detect the inhibitory activity of the compounds of the present invention against in vitro protein kinases using isot...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Indo-Soviet Friendship College Of Pharmacy (Isfcp)

Curated by ChEMBL
LigandPNGBDBM50151366((2-Chloro-6-methyl-phenyl)-[8-((S)-3-methyl-pipera...)
Affinity DataIC50: >5nMAssay Description:Inhibition of Fyn protein kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Indo-Soviet Friendship College Of Pharmacy (Isfcp)

Curated by ChEMBL
LigandPNGBDBM473172((3R,4R)-3-((4-amino-3-(4-phenoxyphenyl)-1H-pyrazol...)
Affinity DataIC50: <5nMAssay Description:IC50 Table 13-20: The protocol calls for test compound of the invention to be incubated with kinase, substrate, cofactors, and radio-isotope-labeled ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Indo-Soviet Friendship College Of Pharmacy (Isfcp)

Curated by ChEMBL
LigandPNGBDBM26028(4-({2-[(3-tert-butylphenyl)(methyl)amino]-1H-1,3-b...)
Affinity DataIC50:  5nMAssay Description:Inhibition of [3H]-FPP incorporation into biotin-linked K-ras decapeptide (CVIM) by bovine farnesyltransferaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Indo-Soviet Friendship College Of Pharmacy (Isfcp)

Curated by ChEMBL
LigandPNGBDBM473171((3R,4S)-3-((4-amino-3-(4-phenoxyphenyl)-1H-pyrazol...)
Affinity DataIC50: <5nMAssay Description:IC50 Table 13-20: The protocol calls for test compound of the invention to be incubated with kinase, substrate, cofactors, and radio-isotope-labeled ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Indo-Soviet Friendship College Of Pharmacy (Isfcp)

Curated by ChEMBL
LigandPNGBDBM378885(US10266537, Compound 93)
Affinity DataIC50:  6nMAssay Description:Inhibition of human full length recombinant FYN using Cdc2 peptide as substrate incubated for 40 mins in presence of [gamma33P-ATP] by radiometric sc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Indo-Soviet Friendship College Of Pharmacy (Isfcp)

Curated by ChEMBL
LigandPNGBDBM25116(1-tert-butyl-3-(4-methylphenyl)-1H-pyrazolo[3,4-d]...)
Affinity DataIC50:  6nMAssay Description:Inhibition of protein tyrosine kinasesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Indo-Soviet Friendship College Of Pharmacy (Isfcp)

Curated by ChEMBL
LigandPNGBDBM50142887(1-(tert-butyl)-3-(4-chlorophenyl)-4-aminopyrazolo[...)
Affinity DataIC50:  6nMAssay Description:The assay procedure determines the IC50 of each potential FYN kinase inhibitor by measuring the enzyme catalyzed ATP-dependent phosphorylation of the...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Indo-Soviet Friendship College Of Pharmacy (Isfcp)

Curated by ChEMBL
LigandPNGBDBM25116(1-tert-butyl-3-(4-methylphenyl)-1H-pyrazolo[3,4-d]...)
Affinity DataIC50:  6nMAssay Description:The assay procedure determines the IC50 of each potential FYN kinase inhibitor by measuring the enzyme catalyzed ATP-dependent phosphorylation of the...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Indo-Soviet Friendship College Of Pharmacy (Isfcp)

Curated by ChEMBL
LigandPNGBDBM378885(US10266537, Compound 93)
Affinity DataIC50:  6nMAssay Description:The aim of this experiment is to detect the inhibitory activity of the compounds of the present invention against in vitro protein kinases using isot...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Indo-Soviet Friendship College Of Pharmacy (Isfcp)

Curated by ChEMBL
LigandPNGBDBM50142887(1-(tert-butyl)-3-(4-chlorophenyl)-4-aminopyrazolo[...)
Affinity DataIC50:  6nMAssay Description:The ADP-Glo™ Kinase Assay is specifically designed to quantify kinase activity by measuring the ADP produced in the reaction The reaction buffer...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Indo-Soviet Friendship College Of Pharmacy (Isfcp)

Curated by ChEMBL
LigandPNGBDBM25116(1-tert-butyl-3-(4-methylphenyl)-1H-pyrazolo[3,4-d]...)
Affinity DataIC50:  6nMAssay Description:The ADP-Glo™ Kinase Assay is specifically designed to quantify kinase activity by measuring the ADP produced in the reaction The reaction buffer...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Indo-Soviet Friendship College Of Pharmacy (Isfcp)

Curated by ChEMBL
LigandPNGBDBM446703(US10688093, Compound B50 (U.S. Pat. No.-8,492,377)...)
Affinity DataIC50:  6.69nMAssay Description:The ADP-Glo™ Kinase Assay is specifically designed to quantify kinase activity by measuring the ADP produced in the reaction The reaction buffer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Indo-Soviet Friendship College Of Pharmacy (Isfcp)

Curated by ChEMBL
LigandPNGBDBM446703(US10688093, Compound B50 (U.S. Pat. No.-8,492,377)...)
Affinity DataIC50:  6.69nMAssay Description:The assay procedure determines the IC50 of each potential FYN kinase inhibitor by measuring the enzyme catalyzed ATP-dependent phosphorylation of the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Indo-Soviet Friendship College Of Pharmacy (Isfcp)

Curated by ChEMBL
LigandPNGBDBM97672(US8476284, 40 | US9133201, 10 | US9181263, 9 | US9...)
Affinity DataIC50:  7.10nMAssay Description:IC50s were determined using the in vitro HotSpot kinase assay (purified enzymes, 33P-ATP, an appropriate substrate and 1 uM ATP.). Reaction condition...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Indo-Soviet Friendship College Of Pharmacy (Isfcp)

Curated by ChEMBL
LigandPNGBDBM97672(US8476284, 40 | US9133201, 10 | US9181263, 9 | US9...)
Affinity DataIC50:  7.10nMAssay Description:IC50s were determined using the in vitro HotSpot kinase assay (purified enzymes, 33P-ATP, an appropriate substrate and 1 μM ATP.). For enzyme in...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Indo-Soviet Friendship College Of Pharmacy (Isfcp)

Curated by ChEMBL
LigandPNGBDBM50577169(CHEMBL4846921)
Affinity DataIC50:  7.70nMAssay Description:Inhibition of Fyn (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Indo-Soviet Friendship College Of Pharmacy (Isfcp)

Curated by ChEMBL
LigandPNGBDBM446705(N-{4-[2-(dimethyl- amino)ethoxy]- 3,5-dimethyl phe...)
Affinity DataIC50:  8nMAssay Description:The ADP-Glo™ Kinase Assay is specifically designed to quantify kinase activity by measuring the ADP produced in the reaction The reaction buffer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Indo-Soviet Friendship College Of Pharmacy (Isfcp)

Curated by ChEMBL
LigandPNGBDBM446704(9-methoxy-N-{3- methoxy-4-[3- (pyrrolidin-1-yl)pro...)
Affinity DataIC50:  8nMAssay Description:The ADP-Glo™ Kinase Assay is specifically designed to quantify kinase activity by measuring the ADP produced in the reaction The reaction buffer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Indo-Soviet Friendship College Of Pharmacy (Isfcp)

Curated by ChEMBL
LigandPNGBDBM446705(N-{4-[2-(dimethyl- amino)ethoxy]- 3,5-dimethyl phe...)
Affinity DataIC50:  8nMAssay Description:The assay procedure determines the IC50 of each potential FYN kinase inhibitor by measuring the enzyme catalyzed ATP-dependent phosphorylation of the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Indo-Soviet Friendship College Of Pharmacy (Isfcp)

Curated by ChEMBL
LigandPNGBDBM446704(9-methoxy-N-{3- methoxy-4-[3- (pyrrolidin-1-yl)pro...)
Affinity DataIC50:  8nMAssay Description:The assay procedure determines the IC50 of each potential FYN kinase inhibitor by measuring the enzyme catalyzed ATP-dependent phosphorylation of the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Indo-Soviet Friendship College Of Pharmacy (Isfcp)

Curated by ChEMBL
LigandPNGBDBM50142887(1-(tert-butyl)-3-(4-chlorophenyl)-4-aminopyrazolo[...)
Affinity DataIC50:  10nMAssay Description:Inhibition of FYN (unknown origin) by cell culture based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Indo-Soviet Friendship College Of Pharmacy (Isfcp)

Curated by ChEMBL
LigandPNGBDBM50184777(CHEMBL3823104 | US10294227, Code 519)
Affinity DataIC50: <10nMAssay Description:Compound IC50 values were determined from 10-point, 1:3 dilution curves starting at either 100 μM or 10 μM with 10 μM ATP, by Reaction...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Indo-Soviet Friendship College Of Pharmacy (Isfcp)

Curated by ChEMBL
LigandPNGBDBM50121391(CHEMBL3622137)
Affinity DataIC50:  10nMAssay Description:Inhibition of recombinant Fyn (unknown origin) using fluoresceinated peptide as substrate after 60 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Indo-Soviet Friendship College Of Pharmacy (Isfcp)

Curated by ChEMBL
LigandPNGBDBM25116(1-tert-butyl-3-(4-methylphenyl)-1H-pyrazolo[3,4-d]...)
Affinity DataIC50:  10nMAssay Description:Inhibition of FYN (unknown origin) by cell culture based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Indo-Soviet Friendship College Of Pharmacy (Isfcp)

Curated by ChEMBL
LigandPNGBDBM13216(BMS-354825 | CHEMBL1421 | DASATINIB | N-(2-Chloro-...)
Affinity DataIC50: <10nMAssay Description:Compound IC50 values were determined from 10-point, 1:3 dilution curves starting at either 100 μM or 10 μM with 10 μM ATP, by Reaction...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Indo-Soviet Friendship College Of Pharmacy (Isfcp)

Curated by ChEMBL
LigandPNGBDBM387836(US10294227, Code 585 | tert-butyl N-[4-[4-amino-1-...)
Affinity DataIC50: <10nMAssay Description:Compound IC50 values were determined from 10-point, 1:3 dilution curves starting at either 100 μM or 10 μM with 10 μM ATP, by Reaction...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Indo-Soviet Friendship College Of Pharmacy (Isfcp)

Curated by ChEMBL
LigandPNGBDBM50184786(CHEMBL3824116 | US10294227, Code 565)
Affinity DataIC50: <10nMAssay Description:Compound IC50 values were determined from 10-point, 1:3 dilution curves starting at either 100 μM or 10 μM with 10 μM ATP, by Reaction...More data for this Ligand-Target Pair
In DepthDetails US Patent
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