TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina
Curated by ChEMBL
University Of Messina
Curated by ChEMBL
Affinity DataKi: 6.20nMAssay Description:Uncompetitive inhibition of human recombinant aldose reductase expressed in Escherichia coli BL21(DE3)pLysS assessed as dissociation constant of enzy...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina
Curated by ChEMBL
University Of Messina
Curated by ChEMBL
Affinity DataKi: 16nMAssay Description:Uncompetitive inhibition of human recombinant aldose reductase expressed in Escherichia coli BL21(DE3)pLysS assessed as dissociation constant of enzy...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina
Curated by ChEMBL
University Of Messina
Curated by ChEMBL
Affinity DataKi: 19nMAssay Description:Inhibition of aldose reductase (aldo-keto reductase, AKR1B1) isolated from human placenta.More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina
Curated by ChEMBL
University Of Messina
Curated by ChEMBL
Affinity DataKi: 66nMAssay Description:Uncompetitive inhibition of recombinant human AKR1B1 using D,L-glyceraldehyde as substrateMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina
Curated by ChEMBL
University Of Messina
Curated by ChEMBL
Affinity DataKi: 150nMAssay Description:The compound was tested for inhibitory activity against aldose reductase from human placentaMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina
Curated by ChEMBL
University Of Messina
Curated by ChEMBL
Affinity DataKi: >300nMAssay Description:Uncompetitive inhibition of human recombinant aldose reductase expressed in Escherichia coli BL21(DE3)pLysS assessed as dissociation constant of enzy...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina
Curated by ChEMBL
University Of Messina
Curated by ChEMBL
Affinity DataKi: 310nMAssay Description:The compound was tested for inhibitory activity against aldose reductase from human placentaMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina
Curated by ChEMBL
University Of Messina
Curated by ChEMBL
Affinity DataKi: 400nMAssay Description:Binding affinity of the compound was determined towards rabbit aldose reductaseMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina
Curated by ChEMBL
University Of Messina
Curated by ChEMBL
Affinity DataKi: >500nMAssay Description:Uncompetitive inhibition of human recombinant aldose reductase expressed in Escherichia coli BL21(DE3)pLysS assessed as dissociation constant of enzy...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina
Curated by ChEMBL
University Of Messina
Curated by ChEMBL
Affinity DataKi: 500nMAssay Description:The compound was tested for inhibitory activity against Aldose reductase from human placentaMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina
Curated by ChEMBL
University Of Messina
Curated by ChEMBL
Affinity DataKi: 950nM ΔG°: -8.21kcal/molepH: 7.0 T: 2°CAssay Description:The production of NADPH from NADP+ and benzyl alcohol and xylitol was monitored by an increase in NADPH fluorescence (ex: 340 nm; em: 460 nm) using a...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina
Curated by ChEMBL
University Of Messina
Curated by ChEMBL
Affinity DataKi: 1.30E+3nMAssay Description:The compound was tested for inhibitory activity against Aldose reductase from human placentaMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina
Curated by ChEMBL
University Of Messina
Curated by ChEMBL
Affinity DataKi: 1.50E+3nM ΔG°: -7.94kcal/molepH: 7.0 T: 2°CAssay Description:The production of NADPH from NADP+ and benzyl alcohol and xylitol was monitored by an increase in NADPH fluorescence (ex: 340 nm; em: 460 nm) using a...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina
Curated by ChEMBL
University Of Messina
Curated by ChEMBL
Affinity DataKi: 1.50E+3nMAssay Description:The compound was tested for inhibitory activity against Aldose reductase from human placentaMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina
Curated by ChEMBL
University Of Messina
Curated by ChEMBL
Affinity DataKi: 2.00E+3nM ΔG°: -7.77kcal/molepH: 7.0 T: 2°CAssay Description:The production of NADPH from NADP+ and benzyl alcohol and xylitol was monitored by an increase in NADPH fluorescence (ex: 340 nm; em: 460 nm) using a...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina
Curated by ChEMBL
University Of Messina
Curated by ChEMBL
Affinity DataKi: 2.11E+3nMAssay Description:Uncompetitive inhibition of human recombinant aldose reductase expressed in Escherichia coli using DL-glyceraldehyde as substrate by double reciproca...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina
Curated by ChEMBL
University Of Messina
Curated by ChEMBL
Affinity DataKi: 2.30E+3nMAssay Description:The production of NADPH from NADP+ and benzyl alcohol and xylitol was monitored by an increase in NADPH fluorescence (ex: 340 nm; em: 460 nm) using a...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina
Curated by ChEMBL
University Of Messina
Curated by ChEMBL
Affinity DataKi: 2.50E+3nM ΔG°: -7.64kcal/molepH: 7.0 T: 2°CAssay Description:The production of NADPH from NADP+ and benzyl alcohol and xylitol was monitored by an increase in NADPH fluorescence (ex: 340 nm; em: 460 nm) using a...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina
Curated by ChEMBL
University Of Messina
Curated by ChEMBL
Affinity DataKi: 2.50E+3nMAssay Description:The compound was tested for inhibitory activity against Aldose reductase from human placentaMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina
Curated by ChEMBL
University Of Messina
Curated by ChEMBL
Affinity DataKi: 2.80E+3nMAssay Description:The compound was tested for inhibitory activity against Aldose reductase from human placentaMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina
Curated by ChEMBL
University Of Messina
Curated by ChEMBL
Affinity DataKi: 3.10E+3nMAssay Description:The compound was tested for inhibitory activity against aldose reductase from human placentaMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina
Curated by ChEMBL
University Of Messina
Curated by ChEMBL
Affinity DataKi: 3.50E+3nM ΔG°: -7.44kcal/molepH: 7.0 T: 2°CAssay Description:The production of NADPH from NADP+ and benzyl alcohol and xylitol was monitored by an increase in NADPH fluorescence (ex: 340 nm; em: 460 nm) using a...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina
Curated by ChEMBL
University Of Messina
Curated by ChEMBL
Affinity DataKi: 3.80E+3nMAssay Description:The production of NADPH from NADP+ and benzyl alcohol and xylitol was monitored by an increase in NADPH fluorescence (ex: 340 nm; em: 460 nm) using a...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina
Curated by ChEMBL
University Of Messina
Curated by ChEMBL
Affinity DataKi: 4.30E+3nMAssay Description:The compound was tested for inhibitory activity against Aldose reductase from human placentaMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina
Curated by ChEMBL
University Of Messina
Curated by ChEMBL
Affinity DataKi: 4.40E+3nM ΔG°: -7.30kcal/molepH: 7.0 T: 2°CAssay Description:The production of NADPH from NADP+ and benzyl alcohol and xylitol was monitored by an increase in NADPH fluorescence (ex: 340 nm; em: 460 nm) using a...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina
Curated by ChEMBL
University Of Messina
Curated by ChEMBL
Affinity DataKi: 4.70E+3nMAssay Description:The compound was tested for inhibitory activity against aldose reductase from human placentaMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina
Curated by ChEMBL
University Of Messina
Curated by ChEMBL
Affinity DataKi: 5.30E+3nMAssay Description:The compound was tested for inhibitory activity against aldose reductase from human placentaMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina
Curated by ChEMBL
University Of Messina
Curated by ChEMBL
Affinity DataKi: 6.20E+3nM ΔG°: -7.10kcal/molepH: 7.0 T: 2°CAssay Description:The production of NADPH from NADP+ and benzyl alcohol and xylitol was monitored by an increase in NADPH fluorescence (ex: 340 nm; em: 460 nm) using a...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina
Curated by ChEMBL
University Of Messina
Curated by ChEMBL
Affinity DataKi: 6.50E+3nMAssay Description:The production of NADPH from NADP+ and benzyl alcohol and xylitol was monitored by an increase in NADPH fluorescence (ex: 340 nm; em: 460 nm) using a...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina
Curated by ChEMBL
University Of Messina
Curated by ChEMBL
Affinity DataKi: 6.80E+3nMAssay Description:The compound was tested for inhibitory activity against aldose reductase from human placentaMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina
Curated by ChEMBL
University Of Messina
Curated by ChEMBL
Affinity DataKi: 7.30E+3nMAssay Description:The compound was tested for inhibitory activity against aldose reductase from human placentaMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina
Curated by ChEMBL
University Of Messina
Curated by ChEMBL
Affinity DataKi: 7.80E+3nMAssay Description:The compound was tested for inhibitory activity against Aldose reductase from human placentaMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina
Curated by ChEMBL
University Of Messina
Curated by ChEMBL
Affinity DataKi: 8.10E+3nMAssay Description:The production of NADPH from NADP+ and benzyl alcohol and xylitol was monitored by an increase in NADPH fluorescence (ex: 340 nm; em: 460 nm) using a...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina
Curated by ChEMBL
University Of Messina
Curated by ChEMBL
Affinity DataKi: 9.30E+3nMAssay Description:The compound was tested for inhibitory activity against Aldose reductase from human placentaMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina
Curated by ChEMBL
University Of Messina
Curated by ChEMBL
Affinity DataKi: 9.70E+3nMAssay Description:The compound was tested for inhibitory activity against Aldose reductase from human placentaMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina
Curated by ChEMBL
University Of Messina
Curated by ChEMBL
Affinity DataKi: 1.30E+4nM ΔG°: -6.66kcal/molepH: 7.0 T: 2°CAssay Description:The production of NADPH from NADP+ and benzyl alcohol and xylitol was monitored by an increase in NADPH fluorescence (ex: 340 nm; em: 460 nm) using a...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina
Curated by ChEMBL
University Of Messina
Curated by ChEMBL
Affinity DataKi: 1.40E+4nMAssay Description:The production of NADPH from NADP+ and benzyl alcohol and xylitol was monitored by an increase in NADPH fluorescence (ex: 340 nm; em: 460 nm) using a...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina
Curated by ChEMBL
University Of Messina
Curated by ChEMBL
Affinity DataKi: 2.55E+4nM ΔG°: -6.26kcal/molepH: 7.0 T: 2°CAssay Description:The production of NADPH from NADP+ and benzyl alcohol and xylitol was monitored by an increase in NADPH fluorescence (ex: 340 nm; em: 460 nm) using a...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina
Curated by ChEMBL
University Of Messina
Curated by ChEMBL
Affinity DataKi: 3.42E+4nM ΔG°: -6.09kcal/molepH: 7.0 T: 2°CAssay Description:The production of NADPH from NADP+ and benzyl alcohol and xylitol was monitored by an increase in NADPH fluorescence (ex: 340 nm; em: 460 nm) using a...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina
Curated by ChEMBL
University Of Messina
Curated by ChEMBL
Affinity DataKi: 3.77E+4nM ΔG°: -6.03kcal/molepH: 7.0 T: 2°CAssay Description:The production of NADPH from NADP+ and benzyl alcohol and xylitol was monitored by an increase in NADPH fluorescence (ex: 340 nm; em: 460 nm) using a...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina
Curated by ChEMBL
University Of Messina
Curated by ChEMBL
Affinity DataKi: 3.80E+4nM ΔG°: -6.03kcal/molepH: 7.0 T: 2°CAssay Description:The production of NADPH from NADP+ and benzyl alcohol and xylitol was monitored by an increase in NADPH fluorescence (ex: 340 nm; em: 460 nm) using a...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina
Curated by ChEMBL
University Of Messina
Curated by ChEMBL
Affinity DataKi: 3.80E+4nM ΔG°: -6.03kcal/molepH: 7.0 T: 2°CAssay Description:The production of NADPH from NADP+ and benzyl alcohol and xylitol was monitored by an increase in NADPH fluorescence (ex: 340 nm; em: 460 nm) using a...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina
Curated by ChEMBL
University Of Messina
Curated by ChEMBL
Affinity DataKi: 4.80E+4nMAssay Description:The compound was tested for inhibitory activity against aldose reductase from human placentaMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina
Curated by ChEMBL
University Of Messina
Curated by ChEMBL
Affinity DataKi: 5.60E+4nMAssay Description:The compound was tested for inhibitory activity against Aldose reductase from human placentaMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina
Curated by ChEMBL
University Of Messina
Curated by ChEMBL
Affinity DataKi: 6.86E+4nM ΔG°: -5.68kcal/molepH: 7.0 T: 2°CAssay Description:The production of NADPH from NADP+ and benzyl alcohol and xylitol was monitored by an increase in NADPH fluorescence (ex: 340 nm; em: 460 nm) using a...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina
Curated by ChEMBL
University Of Messina
Curated by ChEMBL
Affinity DataKi: 8.00E+4nM ΔG°: -5.59kcal/molepH: 7.0 T: 2°CAssay Description:The production of NADPH from NADP+ and benzyl alcohol and xylitol was monitored by an increase in NADPH fluorescence (ex: 340 nm; em: 460 nm) using a...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina
Curated by ChEMBL
University Of Messina
Curated by ChEMBL
Affinity DataKi: 8.60E+4nM ΔG°: -5.54kcal/molepH: 7.0 T: 2°CAssay Description:The production of NADPH from NADP+ and benzyl alcohol and xylitol was monitored by an increase in NADPH fluorescence (ex: 340 nm; em: 460 nm) using a...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina
Curated by ChEMBL
University Of Messina
Curated by ChEMBL
Affinity DataKi: 9.60E+4nM ΔG°: -5.48kcal/molepH: 7.0 T: 2°CAssay Description:The production of NADPH from NADP+ and benzyl alcohol and xylitol was monitored by an increase in NADPH fluorescence (ex: 340 nm; em: 460 nm) using a...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina
Curated by ChEMBL
University Of Messina
Curated by ChEMBL
Affinity DataKi: 2.80E+5nM ΔG°: -4.84kcal/molepH: 7.0 T: 2°CAssay Description:The production of NADPH from NADP+ and benzyl alcohol and xylitol was monitored by an increase in NADPH fluorescence (ex: 340 nm; em: 460 nm) using a...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Messina
Curated by ChEMBL
University Of Messina
Curated by ChEMBL
Affinity DataKi: 3.61E+5nM ΔG°: -4.69kcal/molepH: 7.0 T: 2°CAssay Description:The production of NADPH from NADP+ and benzyl alcohol and xylitol was monitored by an increase in NADPH fluorescence (ex: 340 nm; em: 460 nm) using a...More data for this Ligand-Target Pair