Compile Data Set for Download or QSAR
Report error Found 26 of ki for UniProtKB: O95372
TargetAcyl-protein thioesterase 2(Human)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50336546BDBM50336546(Palmostatin B | CHEMBL1673415)
Affinity DataKi:  34nMAssay Description:Inhibition of APT2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetAcyl-protein thioesterase 2(Human)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 207992BDBM207992(ML349)
Affinity DataKi:  120nMAssay Description:Binding affinity to human APT2 assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetAcyl-protein thioesterase 2(Human)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 207992BDBM207992(ML349)
Affinity DataKi:  120nMAssay Description:Competitive inhibition of HEK293T cells-derived His-tagged APT2 expressed in Escherichia coli BL21(DE3) preincubated for 30 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2018
Entry Details Article
PubMed
TargetAcyl-protein thioesterase 2(Human)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 207992BDBM207992(ML349)
Affinity DataKi:  120nMpH: 6.5Assay Description:Enzymes were diluted to 10 nM in PBS pH 6.5 (adjusted with sodium acetate) supplemented with 0.1 g/L pluronic F127 (Sigma). Varying concentrations of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2017
Entry Details Article
PubMed
TargetAcyl-protein thioesterase 2 [P86Q](Human)
University of Michigan

LigandChemical structure of BindingDB Monomer ID 207992BDBM207992(ML349)
Affinity DataKi:  130nMpH: 6.5Assay Description:Enzymes were diluted to 10 nM in PBS pH 6.5 (adjusted with sodium acetate) supplemented with 0.1 g/L pluronic F127 (Sigma). Varying concentrations of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2017
Entry Details Article
PubMed
TargetAcyl-protein thioesterase 2 [M178L](Human)
University of Michigan

LigandChemical structure of BindingDB Monomer ID 207992BDBM207992(ML349)
Affinity DataKi:  200nMpH: 6.5Assay Description:Enzymes were diluted to 10 nM in PBS pH 6.5 (adjusted with sodium acetate) supplemented with 0.1 g/L pluronic F127 (Sigma). Varying concentrations of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2017
Entry Details Article
PubMed
TargetAcyl-protein thioesterase 2(Human)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 207992BDBM207992(ML349)
Affinity DataKi:  230nMAssay Description:Inhibition of APT2 (unknown origin) by FluPol-ABPP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 207991BDBM207991(ML348)
Affinity DataKi:  430nMpH: 6.5Assay Description:Enzymes were diluted to 10 nM in PBS pH 6.5 (adjusted with sodium acetate) supplemented with 0.1 g/L pluronic F127 (Sigma). Varying concentrations of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2017
Entry Details Article
PubMed
TargetAcyl-protein thioesterase 2 [H152R](Human)
University of Michigan

LigandChemical structure of BindingDB Monomer ID 207992BDBM207992(ML349)
Affinity DataKi:  660nMpH: 6.5Assay Description:Enzymes were diluted to 10 nM in PBS pH 6.5 (adjusted with sodium acetate) supplemented with 0.1 g/L pluronic F127 (Sigma). Varying concentrations of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2017
Entry Details Article
PubMed
TargetAcyl-protein thioesterase 2(Human)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50496627BDBM50496627(CHEMBL3133032)
Affinity DataKi:  730nMAssay Description:Inhibition of APT2 (unknown origin) by enzyme kinetic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetAcyl-protein thioesterase 2(Human)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50496627BDBM50496627(CHEMBL3133032)
Affinity DataKi:  730nMAssay Description:Binding affinity to APT2 (unknown origin) assessed as inhibition constant incubated for 1 hr by Surface plasmon resonance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetAcyl-protein thioesterase 2(Human)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50212216BDBM50212216(CHEMBL3944678)
Affinity DataKi:  1.10E+3nMAssay Description:Competitive inhibition of HEK293T cells-derived His-tagged APT2 expressed in Escherichia coli BL21(DE3) preincubated for 30 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2018
Entry Details Article
PubMed
TargetAcyl-protein thioesterase 2 [L78I,A85S,P86Q](Human)
University of Michigan

LigandChemical structure of BindingDB Monomer ID 207991BDBM207991(ML348)
Affinity DataKi:  3.40E+3nMpH: 6.5Assay Description:Enzymes were diluted to 10 nM in PBS pH 6.5 (adjusted with sodium acetate) supplemented with 0.1 g/L pluronic F127 (Sigma). Varying concentrations of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2017
Entry Details Article
PubMed
TargetAcyl-protein thioesterase 2 [L78I](Human)
University of Michigan

LigandChemical structure of BindingDB Monomer ID 207991BDBM207991(ML348)
Affinity DataKi:  5.80E+3nMpH: 6.5Assay Description:Enzymes were diluted to 10 nM in PBS pH 6.5 (adjusted with sodium acetate) supplemented with 0.1 g/L pluronic F127 (Sigma). Varying concentrations of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2017
Entry Details Article
PubMed
TargetAcyl-protein thioesterase 2 [L78I,A85S](Human)
University of Michigan

LigandChemical structure of BindingDB Monomer ID 207991BDBM207991(ML348)
Affinity DataKi:  6.20E+3nMpH: 6.5Assay Description:Enzymes were diluted to 10 nM in PBS pH 6.5 (adjusted with sodium acetate) supplemented with 0.1 g/L pluronic F127 (Sigma). Varying concentrations of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2017
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 207992BDBM207992(ML349)
Affinity DataKi: >1.00E+4nMpH: 6.5Assay Description:Enzymes were diluted to 10 nM in PBS pH 6.5 (adjusted with sodium acetate) supplemented with 0.1 g/L pluronic F127 (Sigma). Varying concentrations of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2017
Entry Details Article
PubMed
TargetAcyl-protein thioesterase 2 [L78I](Human)
University of Michigan

LigandChemical structure of BindingDB Monomer ID 207992BDBM207992(ML349)
Affinity DataKi: >1.00E+4nMpH: 6.5Assay Description:Enzymes were diluted to 10 nM in PBS pH 6.5 (adjusted with sodium acetate) supplemented with 0.1 g/L pluronic F127 (Sigma). Varying concentrations of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2017
Entry Details Article
PubMed
TargetAcyl-protein thioesterase 2(Human)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 207991BDBM207991(ML348)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of APT2 (unknown origin) by FluPol-ABPP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetAcyl-protein thioesterase 2 [H152R](Human)
University of Michigan

LigandChemical structure of BindingDB Monomer ID 207991BDBM207991(ML348)
Affinity DataKi: >1.00E+4nMpH: 6.5Assay Description:Enzymes were diluted to 10 nM in PBS pH 6.5 (adjusted with sodium acetate) supplemented with 0.1 g/L pluronic F127 (Sigma). Varying concentrations of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2017
Entry Details Article
PubMed
TargetAcyl-protein thioesterase 2 [P86Q](Human)
University of Michigan

LigandChemical structure of BindingDB Monomer ID 207991BDBM207991(ML348)
Affinity DataKi: >1.00E+4nMpH: 6.5Assay Description:Enzymes were diluted to 10 nM in PBS pH 6.5 (adjusted with sodium acetate) supplemented with 0.1 g/L pluronic F127 (Sigma). Varying concentrations of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2017
Entry Details Article
PubMed
TargetAcyl-protein thioesterase 2 [L78I,A85S,P86Q](Human)
University of Michigan

LigandChemical structure of BindingDB Monomer ID 207992BDBM207992(ML349)
Affinity DataKi: >1.00E+4nMpH: 6.5Assay Description:Enzymes were diluted to 10 nM in PBS pH 6.5 (adjusted with sodium acetate) supplemented with 0.1 g/L pluronic F127 (Sigma). Varying concentrations of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2017
Entry Details Article
PubMed
TargetAcyl-protein thioesterase 2 [L78I,A85S](Human)
University of Michigan

LigandChemical structure of BindingDB Monomer ID 207992BDBM207992(ML349)
Affinity DataKi: >1.00E+4nMpH: 6.5Assay Description:Enzymes were diluted to 10 nM in PBS pH 6.5 (adjusted with sodium acetate) supplemented with 0.1 g/L pluronic F127 (Sigma). Varying concentrations of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2017
Entry Details Article
PubMed
TargetAcyl-protein thioesterase 2(Human)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50212218BDBM50212218(CHEMBL3974081)
Affinity DataKi: >1.00E+4nMAssay Description:Competitive inhibition of HEK293T cells-derived His-tagged APT2 expressed in Escherichia coli BL21(DE3) preincubated for 30 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2018
Entry Details Article
PubMed
TargetAcyl-protein thioesterase 2(Human)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50212217BDBM50212217(CHEMBL3917640)
Affinity DataKi: >1.00E+4nMAssay Description:Competitive inhibition of HEK293T cells-derived His-tagged APT2 expressed in Escherichia coli BL21(DE3) preincubated for 30 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2018
Entry Details Article
PubMed
TargetAcyl-protein thioesterase 2 [M178L](Human)
University of Michigan

LigandChemical structure of BindingDB Monomer ID 207991BDBM207991(ML348)
Affinity DataKi: >1.00E+4nMpH: 6.5Assay Description:Enzymes were diluted to 10 nM in PBS pH 6.5 (adjusted with sodium acetate) supplemented with 0.1 g/L pluronic F127 (Sigma). Varying concentrations of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2017
Entry Details Article
PubMed
TargetAcyl-protein thioesterase 2(Human)
University of Michigan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 207991BDBM207991(ML348)
Affinity DataKi: >1.00E+4nMpH: 6.5Assay Description:Enzymes were diluted to 10 nM in PBS pH 6.5 (adjusted with sodium acetate) supplemented with 0.1 g/L pluronic F127 (Sigma). Varying concentrations of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2017
Entry Details Article
PubMed