Compile Data Set for Download or QSAR
Found 2 of ic50 for UniProtKB: P23458
TargetTyrosine-protein kinase JAK1 [852-1142](Homo sapiens (Human))
Zoetis Services LLC

US Patent
LigandPNGBDBM185700(US10875847, Compound Oclacitinib | US9161939, 1a |...)
Show SMILES CNS(=O)(=O)C[C@H]1CC[C@@H](CC1)N(C)c1ncnc2[nH]ccc12
Affinity DataIC50: 9.53nMpH: 7.4Assay Description:Methods: A peptide mobility shift assay was used to quantify the phosphorylation of the JAKtide (JAK-2 and JAK-3) or the IRS-1 peptide (JAK-1 and Tyk...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK1 [852-1142](Homo sapiens (Human))
Zoetis Services LLC

US Patent
LigandPNGBDBM185701(US9161939, 2 | US9271981, 2)
Show SMILES CN([C@H]1CC[C@H](CS(=O)(=O)NC2CCC2)CC1)c1ncnc2[nH]ccc12
Affinity DataIC50: 45nMpH: 7.4Assay Description:Methods: A peptide mobility shift assay was used to quantify the phosphorylation of the JAKtide (JAK-2 and JAK-3) or the IRS-1 peptide (JAK-1 and Tyk...More data for this Ligand-Target Pair