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Report error Found 1313 of ic50 for UniProtKB: P00918
TargetCarbonic anhydrase 2(Human)
Anadolu University

Curated by ChEMBL
LigandPNGBDBM50252998(CHEMBL4105008)
Affinity DataIC50: 0.150nMAssay Description:Inhibition of carbonic anhydrase-2 in human erythrocyte membranes assessed as reduction in H+ release using CO2 as substrate by bromine thymol blue i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2019
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Anadolu University

Curated by ChEMBL
LigandPNGBDBM50252992(CHEMBL4100496)
Affinity DataIC50: 0.190nMAssay Description:Inhibition of carbonic anhydrase-2 in human erythrocyte membranes assessed as reduction in H+ release using CO2 as substrate by bromine thymol blue i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2019
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Anadolu University

Curated by ChEMBL
LigandPNGBDBM10884((2S,4S)-4-(ethylamino)-2-methyl-1,1-dioxo-2H,3H,4H...)
Affinity DataIC50: 0.230nMAssay Description:Compound was evaluated for the inhibitory activity against Human Carbonic anhydrase II (HCA II)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 2(Human)
Anadolu University

Curated by ChEMBL
LigandPNGBDBM222054((3aR,4S,7R,7aS)-2-(4-((E)-3-(4-bromophenyl)acryloy...)
Affinity DataKi:  0.245nM ΔG°:  -13.1kcal/mole IC50: 0.352nMpH: 7.4 T: 2°CAssay Description:Esterase activity assay was performed based on the method of by Verpoorte et al. [Verpoorte et al., J. Biol. Chem., 242:4221-4229] as described in pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Anadolu University

Curated by ChEMBL
LigandPNGBDBM222051((3aR,4S,7R,7aS)-2-(4-((E)-3-(4-chlorophenyl)acrylo...)
Affinity DataKi:  0.258nM ΔG°:  -13.1kcal/mole IC50: 0.373nMpH: 7.4 T: 2°CAssay Description:Esterase activity assay was performed based on the method of by Verpoorte et al. [Verpoorte et al., J. Biol. Chem., 242:4221-4229] as described in pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Anadolu University

Curated by ChEMBL
LigandPNGBDBM222046((3aR,4S,7R,7aS)-2-(4-((E)-3-(4-methoxyphenyl)acryl...)
Affinity DataKi:  0.277nM ΔG°:  -13.0kcal/mole IC50: 0.356nMpH: 7.4 T: 2°CAssay Description:Esterase activity assay was performed based on the method of by Verpoorte et al. [Verpoorte et al., J. Biol. Chem., 242:4221-4229] as described in pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Anadolu University

Curated by ChEMBL
LigandPNGBDBM50258992(CHEMBL4081323)
Affinity DataIC50: 0.287nMAssay Description:Inhibition of human erythrocyte carbonic anhydrase-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2019
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Anadolu University

Curated by ChEMBL
LigandPNGBDBM10882(6-ethoxy-1,3-benzothiazole-2-sulfonamide | Ethoxzo...)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of full length carbonic anhydrase-2 in human erythrocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 2(Human)
Anadolu University

Curated by ChEMBL
LigandPNGBDBM222050((3aR,4S,7R,7aS)-2-(4-((E)-3-(o-tolyl)acryloyl)phen...)
Affinity DataKi:  0.302nM ΔG°:  -13.0kcal/mole IC50: 0.353nMpH: 7.4 T: 2°CAssay Description:Esterase activity assay was performed based on the method of by Verpoorte et al. [Verpoorte et al., J. Biol. Chem., 242:4221-4229] as described in pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Anadolu University

Curated by ChEMBL
LigandPNGBDBM222047((3aR,4S,7R,7aS)-2-(4-((E)-3-(3-methoxyphenyl)acryl...)
Affinity DataKi:  0.337nM ΔG°:  -12.9kcal/mole IC50: 0.435nMpH: 7.4 T: 2°CAssay Description:Esterase activity assay was performed based on the method of by Verpoorte et al. [Verpoorte et al., J. Biol. Chem., 242:4221-4229] as described in pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Anadolu University

Curated by ChEMBL
LigandPNGBDBM50258998(CHEMBL4099344)
Affinity DataIC50: 0.338nMAssay Description:Inhibition of human erythrocyte carbonic anhydrase-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2019
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Anadolu University

Curated by ChEMBL
LigandPNGBDBM50252993(CHEMBL4073678)
Affinity DataIC50: 0.340nMAssay Description:Inhibition of carbonic anhydrase-2 in human erythrocyte membranes assessed as reduction in H+ release using CO2 as substrate by bromine thymol blue i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2019
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Anadolu University

Curated by ChEMBL
LigandPNGBDBM222055((3aR,4S,7R,7aS)-2-(4-((E)-3-(3-bromophenyl)acryloy...)
Affinity DataKi:  0.343nM ΔG°:  -12.9kcal/mole IC50: 0.382nMpH: 7.4 T: 2°CAssay Description:Esterase activity assay was performed based on the method of by Verpoorte et al. [Verpoorte et al., J. Biol. Chem., 242:4221-4229] as described in pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Anadolu University

Curated by ChEMBL
LigandPNGBDBM10880(Acetazolamide, AAZ | AZA2 | CHEMBL20 | Acetazolami...)
Affinity DataKi:  0.343nM ΔG°:  -12.9kcal/mole IC50: 0.485nMpH: 7.4 T: 2°CAssay Description:Esterase activity assay was performed based on the method of by Verpoorte et al. [Verpoorte et al., J. Biol. Chem., 242:4221-4229] as described in pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 2(Human)
Anadolu University

Curated by ChEMBL
LigandPNGBDBM222052((3aR,4S,7R,7aS)-2-(4-((E)-3-(3-chlorophenyl)acrylo...)
Affinity DataKi:  0.361nM ΔG°:  -12.9kcal/mole IC50: 0.419nMpH: 7.4 T: 2°CAssay Description:Esterase activity assay was performed based on the method of by Verpoorte et al. [Verpoorte et al., J. Biol. Chem., 242:4221-4229] as described in pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Anadolu University

Curated by ChEMBL
LigandPNGBDBM222053((3aR,4S,7R,7aS)-2-(4-((E)-3-(2-chlorophenyl)acrylo...)
Affinity DataKi:  0.377nM ΔG°:  -12.8kcal/mole IC50: 0.444nMpH: 7.4 T: 2°CAssay Description:Esterase activity assay was performed based on the method of by Verpoorte et al. [Verpoorte et al., J. Biol. Chem., 242:4221-4229] as described in pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Anadolu University

Curated by ChEMBL
LigandPNGBDBM222056((3aR,4S,7R,7aS)-2-(4-((E)-3-(2-bromophenyl)acryloy...)
Affinity DataKi:  0.379nM ΔG°:  -12.8kcal/mole IC50: 0.415nMpH: 7.4 T: 2°CAssay Description:Esterase activity assay was performed based on the method of by Verpoorte et al. [Verpoorte et al., J. Biol. Chem., 242:4221-4229] as described in pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Anadolu University

Curated by ChEMBL
LigandPNGBDBM222057((3aR,4S,7R,7aS)-2-(4-((E)-3-(furan-2-yl)acryloyl)p...)
Affinity DataKi:  0.390nM ΔG°:  -12.8kcal/mole IC50: 0.555nMpH: 7.4 T: 2°CAssay Description:Esterase activity assay was performed based on the method of by Verpoorte et al. [Verpoorte et al., J. Biol. Chem., 242:4221-4229] as described in pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Anadolu University

Curated by ChEMBL
LigandPNGBDBM50252996(CHEMBL4097972)
Affinity DataIC50: 0.390nMAssay Description:Inhibition of carbonic anhydrase-2 in human erythrocyte membranes assessed as reduction in H+ release using CO2 as substrate by bromine thymol blue i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2019
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Anadolu University

Curated by ChEMBL
LigandPNGBDBM50515806(CHEMBL4533252)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of human carbonic anhydrase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Anadolu University

Curated by ChEMBL
LigandPNGBDBM222048((3aR,4S,7R,7aS)-2-(4-((E)-3-(p-tolyl)acryloyl)phen...)
Affinity DataKi:  0.400nM ΔG°:  -12.8kcal/mole IC50: 0.406nMpH: 7.4 T: 2°CAssay Description:Esterase activity assay was performed based on the method of by Verpoorte et al. [Verpoorte et al., J. Biol. Chem., 242:4221-4229] as described in pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Anadolu University

Curated by ChEMBL
LigandPNGBDBM222049((3aR,4S,7R,7aS)-2-(4-((E)-3-(m-tolyl)acryloyl)phen...)
Affinity DataKi:  0.404nM ΔG°:  -12.8kcal/mole IC50: 0.449nMpH: 7.4 T: 2°CAssay Description:Esterase activity assay was performed based on the method of by Verpoorte et al. [Verpoorte et al., J. Biol. Chem., 242:4221-4229] as described in pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Anadolu University

Curated by ChEMBL
LigandPNGBDBM50252995(CHEMBL4075535)
Affinity DataIC50: 0.410nMAssay Description:Inhibition of carbonic anhydrase-2 in human erythrocyte membranes assessed as reduction in H+ release using CO2 as substrate by bromine thymol blue i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2019
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Anadolu University

Curated by ChEMBL
LigandPNGBDBM222058((3aR,4S,7R,7aS)-2-(4-((E)-3-(thiophen-2-yl)acryloy...)
Affinity DataKi:  0.412nM ΔG°:  -12.8kcal/mole IC50: 0.488nMpH: 7.4 T: 2°CAssay Description:Esterase activity assay was performed based on the method of by Verpoorte et al. [Verpoorte et al., J. Biol. Chem., 242:4221-4229] as described in pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Anadolu University

Curated by ChEMBL
LigandPNGBDBM50537511(CHEMBL4633178)
Affinity DataIC50: 0.460nMAssay Description:Inhibition of human carbonic anhydrase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Anadolu University

Curated by ChEMBL
LigandPNGBDBM50537510(CHEMBL4644942)
Affinity DataIC50: 0.460nMAssay Description:Inhibition of human carbonic anhydrase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Anadolu University

Curated by ChEMBL
LigandPNGBDBM50253004(CHEMBL4072122)
Affinity DataIC50: 0.470nMAssay Description:Inhibition of carbonic anhydrase-2 in human erythrocyte membranes assessed as reduction in H+ release using CO2 as substrate by bromine thymol blue i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2019
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Anadolu University

Curated by ChEMBL
LigandPNGBDBM222059((3aR,4S,7R,7aS)-2-(4-((E)-3-(pyridin-4-yl)acryloyl...)
Affinity DataKi:  0.490nM ΔG°:  -12.7kcal/mole IC50: 0.551nMpH: 7.4 T: 2°CAssay Description:Esterase activity assay was performed based on the method of by Verpoorte et al. [Verpoorte et al., J. Biol. Chem., 242:4221-4229] as described in pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Anadolu University

Curated by ChEMBL
LigandPNGBDBM50252991(CHEMBL4064130)
Affinity DataIC50: 0.530nMAssay Description:Inhibition of carbonic anhydrase-2 in human erythrocyte membranes assessed as reduction in H+ release using CO2 as substrate by bromine thymol blue i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2019
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Anadolu University

Curated by ChEMBL
LigandPNGBDBM50041029(CHEMBL417975 | 4-Isopropylamino-7,7-dioxo-4,5,6,7-...)
Affinity DataIC50: 0.540nMAssay Description:Compound was evaluated for the inhibitory activity against Human Carbonic anhydrase II (HCA II)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Anadolu University

Curated by ChEMBL
LigandPNGBDBM11425(2-(3-hydroxyphenyl)-1,1-dioxo-3-[(prop-2-yn-1-ylam...)
Affinity DataIC50: 0.600nMAssay Description:The assay measured the rate of CO2 hydration by determining the addition rate of a NaOH solution using a Radiometer VIT 90 titration system. The enzy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Anadolu University

Curated by ChEMBL
LigandPNGBDBM13073(2000-07790 | 3-nitro-4-(2-oxopyrrolidin-1-yl)benze...)
Affinity DataIC50: 0.620nMpH: 7.4 T: 2°CAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/15/2007
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Anadolu University

Curated by ChEMBL
LigandPNGBDBM50258993(CHEMBL4062231)
Affinity DataIC50: 0.622nMAssay Description:Inhibition of human erythrocyte carbonic anhydrase-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2019
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Anadolu University

Curated by ChEMBL
LigandPNGBDBM50258997(CHEMBL4089189)
Affinity DataIC50: 0.651nMAssay Description:Inhibition of human erythrocyte carbonic anhydrase-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2019
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Anadolu University

Curated by ChEMBL
LigandPNGBDBM11413(Compound 17g1 | 2-cyclohexyl-3-(morpholin-4-ylmeth...)
Affinity DataIC50: 0.790nMAssay Description:The assay measured the rate of CO2 hydration by determining the addition rate of a NaOH solution using a Radiometer VIT 90 titration system. The enzy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Anadolu University

Curated by ChEMBL
LigandPNGBDBM50258990(CHEMBL4090426)
Affinity DataIC50: 0.799nMAssay Description:Inhibition of human erythrocyte carbonic anhydrase-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2019
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Anadolu University

Curated by ChEMBL
LigandPNGBDBM511554(tert-butyl 4-(2-fluoro-4- sulfamoylphenyl)sulfonyl...)
Affinity DataIC50: 0.800nMAssay Description:Human carbonic anhydrase II (hCA-II) inhibition was measured by an absorbance method using 4-nitrophenyl acetate (4-NPA) as its substrate. 4-NPA can ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2022
Entry Details
US Patent

TargetCarbonic anhydrase 2(Human)
Anadolu University

Curated by ChEMBL
LigandPNGBDBM50258994(CHEMBL4072105)
Affinity DataIC50: 0.802nMAssay Description:Inhibition of human erythrocyte carbonic anhydrase-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2019
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Anadolu University

Curated by ChEMBL
LigandPNGBDBM13077(5-(thiophene-2-sulfonyl)thiophene-2-sulfonamide | ...)
Affinity DataIC50: 0.810nMpH: 7.4 T: 2°CAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/15/2007
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Anadolu University

Curated by ChEMBL
LigandPNGBDBM11394(Compound 5b | 2-[2-(4-Morpholinyl)ethyl]-2H-thieno...)
Affinity DataIC50: 0.820nMpH: 7.2 T: 2°CAssay Description:The assay measured the rate of CO2 hydration by determining the addition rate of a NaOH solution using a Radiometer VIT 90 titration system. The enzy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Anadolu University

Curated by ChEMBL
LigandPNGBDBM50258996(CHEMBL4069396)
Affinity DataIC50: 0.855nMAssay Description:Inhibition of human erythrocyte carbonic anhydrase-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2019
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Anadolu University

Curated by ChEMBL
LigandPNGBDBM13068(5-(thiophen-2-ylsulfanyl)thiophene-2-sulfonamide |...)
Affinity DataIC50: 0.890nMpH: 7.4 T: 2°CAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/15/2007
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Anadolu University

Curated by ChEMBL
LigandPNGBDBM11393(2-{2-[bis(2-methoxyethyl)amino]ethyl}-1,1-dioxo-2H...)
Affinity DataIC50: 0.910nMpH: 7.2 T: 2°CAssay Description:The assay measured the rate of CO2 hydration by determining the addition rate of a NaOH solution using a Radiometer VIT 90 titration system. The enzy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Anadolu University

Curated by ChEMBL
LigandPNGBDBM11405(Compound 17b4 | 2-Ethyl-3-[[bis(2-hydroxyethyl)ami...)
Affinity DataIC50: 0.960nMAssay Description:The assay measured the rate of CO2 hydration by determining the addition rate of a NaOH solution using a Radiometer VIT 90 titration system. The enzy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Anadolu University

Curated by ChEMBL
LigandPNGBDBM11395(Compound 5c | 2-[2-[4-Acetyl-(1-piperazinyl)]ethyl...)
Affinity DataIC50: 0.960nMpH: 7.2 T: 2°CAssay Description:The assay measured the rate of CO2 hydration by determining the addition rate of a NaOH solution using a Radiometer VIT 90 titration system. The enzy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Anadolu University

Curated by ChEMBL
LigandPNGBDBM11411(3-(morpholin-4-ylmethyl)-1,1-dioxo-2-(prop-2-en-1-...)
Affinity DataIC50: 0.990nMAssay Description:The assay measured the rate of CO2 hydration by determining the addition rate of a NaOH solution using a Radiometer VIT 90 titration system. The enzy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2006
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Anadolu University

Curated by ChEMBL
LigandPNGBDBM442722(US10647719, Example 3.00 | US10647719, Example 3.0...)
Affinity DataIC50: 1nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2021
Entry Details
US Patent

TargetCarbonic anhydrase 2(Human)
Anadolu University

Curated by ChEMBL
LigandPNGBDBM442736(US10647719, Example 1.33 | 4-[5-[2-cyclopropyl-6-(...)
Affinity DataIC50: 1nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2021
Entry Details
US Patent

TargetCarbonic anhydrase 2(Human)
Anadolu University

Curated by ChEMBL
LigandPNGBDBM442717(BDBM442732 | [3-(2,2-dimethylpropanoylamino)-5- | ...)
Affinity DataIC50: 1nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2021
Entry Details
US Patent

TargetCarbonic anhydrase 2(Human)
Anadolu University

Curated by ChEMBL
LigandPNGBDBM442719(US10647719, Example 2.01 | [4-(trifluoromethoxy)ph...)
Affinity DataIC50: 1nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2021
Entry Details
US Patent

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