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Report error Found 433 of ki for UniProtKB: Q14416
TargetMetabotropic glutamate receptor 2(Human)
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM85212(CAS_5311260 | NSC_5311260 | LY341495)
Affinity DataKi:  0.0780nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM213122(US9278960, 8-29 | US9636337, 8-29)
Affinity DataKi:  0.190nMAssay Description:Binding affinity to human mGluR2 expressed in cell membrane incubated for 1 hr in presence of tritium labeled [3H]-7-((2,5-dioxopyrrolidin-1-yl)methy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMetabotropic glutamate receptor 2(Human)
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM50618878(CHEMBL5405921)
Affinity DataKi:  0.320nMAssay Description:Binding affinity to human mGluR2 expressed in cell membrane incubated for 1 hr in presence of tritium labeled [3H]-7-((2,5-dioxopyrrolidin-1-yl)methy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMetabotropic glutamate receptor 2(Human)
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM50034503(DCG-IV | (2S,2'R,3'R)-2-(2',3')-dicarboxycycloprop...)
Affinity DataKi:  0.368nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM50004899(L-CCG-IV | 2-(Amino-carboxy-methyl)-cyclopropaneca...)
Affinity DataKi:  0.378nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM213143(US9278960, 8-50 | US9636337, 8-50)
Affinity DataKi:  0.460nMAssay Description:Binding affinity to human mGluR2 expressed in cell membrane incubated for 1 hr in presence of tritium labeled [3H]-7-((2,5-dioxopyrrolidin-1-yl)methy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMetabotropic glutamate receptor 2(Human)
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM50618874(CHEMBL5409898)
Affinity DataKi:  0.700nMAssay Description:Binding affinity to human mGluR2 expressed in cell membrane incubated for 1 hr in presence of tritium labeled [3H]-7-((2,5-dioxopyrrolidin-1-yl)methy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMetabotropic glutamate receptor 2(Human)
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM50618881(CHEMBL5418895)
Affinity DataKi:  0.740nMAssay Description:Binding affinity to human mGluR2 expressed in cell membrane incubated for 1 hr in presence of tritium labeled [3H]-7-((2,5-dioxopyrrolidin-1-yl)methy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMetabotropic glutamate receptor 2(Human)
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM50618876(CHEMBL5429000)
Affinity DataKi:  0.780nMAssay Description:Binding affinity to human mGluR2 expressed in cell membrane incubated for 1 hr in presence of tritium labeled [3H]-7-((2,5-dioxopyrrolidin-1-yl)methy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMetabotropic glutamate receptor 2(Human)
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM50618875(CHEMBL5394450)
Affinity DataKi:  0.800nMAssay Description:Binding affinity to human mGluR2 expressed in cell membrane incubated for 1 hr in presence of tritium labeled [3H]-7-((2,5-dioxopyrrolidin-1-yl)methy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMetabotropic glutamate receptor 2(Human)
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM50257518(CHEMBL4063313)
Affinity DataKi:  0.891nMAssay Description:Displacement of [3H]-JNJ46281222 from human metabotropic glutamate receptor 2 expressed in CHOK1 cell membranes after 60 mins by microbeta counting a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM50618871(CHEMBL5435246)
Affinity DataKi:  0.960nMAssay Description:Binding affinity to human mGluR2 expressed in cell membrane incubated for 1 hr in presence of tritium labeled [3H]-7-((2,5-dioxopyrrolidin-1-yl)methy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMetabotropic glutamate receptor 2(Human)
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM50618873(CHEMBL5429261)
Affinity DataKi:  1nMAssay Description:Binding affinity to human mGluR2 expressed in cell membrane incubated for 1 hr in presence of tritium labeled [3H]-7-((2,5-dioxopyrrolidin-1-yl)methy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMetabotropic glutamate receptor 2(Human)
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM50209103(CHEMBL3885379)
Affinity DataKi:  1nMAssay Description:Displacement of [3H]-JNJ-40068782 from human mGlu2 receptor expressed in HEK293 cell membranes coexpressing rat glutamate transporter measured after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2018
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM50151448((1R,2R,3R,5R,6R)-2-Amino-3-(3-carboxy-benzyloxy)-6...)
Affinity DataKi:  1.06nMAssay Description:Binding affinity towards metabotropic glutamate receptor 2 of rat expressed in CHO cells was determined by using [3H]MGS-0008More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM213109(US9278960, 8-16 | US9636337, 8-16)
Affinity DataKi:  1.10nMAssay Description:Binding affinity to human mGluR2 expressed in cell membrane incubated for 1 hr in presence of tritium labeled [3H]-7-((2,5-dioxopyrrolidin-1-yl)methy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMetabotropic glutamate receptor 2(Human)
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM50618870(CHEMBL5436775)
Affinity DataKi:  1.10nMAssay Description:Binding affinity to human mGluR2 expressed in cell membrane incubated for 1 hr in presence of tritium labeled [3H]-7-((2,5-dioxopyrrolidin-1-yl)methy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMetabotropic glutamate receptor 2(Human)
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM213108(US9278960, 8-15 | US9636337, 8-15)
Affinity DataKi:  1.40nMAssay Description:Binding affinity to human mGluR2 expressed in cell membrane incubated for 1 hr in presence of tritium labeled [3H]-7-((2,5-dioxopyrrolidin-1-yl)methy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMetabotropic glutamate receptor 2(Human)
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM50151486((1R,2R,3R,5R,6R)-2-Amino-3-[(R)-1-(3,4-dichloro-ph...)
Affinity DataKi:  1.45nMAssay Description:Binding affinity towards metabotropic glutamate receptor 2 of rat expressed in CHO cells was determined by using [3H]MGS-0008More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM50151439((1R,2R,3R,5R,6R)-2-Amino-3-[(R)-1-(3,4-dichloro-ph...)
Affinity DataKi:  1.48nMAssay Description:Binding affinity towards metabotropic glutamate receptor 2 of rat expressed in CHO cells was determined by using [3H]MGS-0008More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM50618879(CHEMBL5405655)
Affinity DataKi:  1.5nMAssay Description:Binding affinity to human mGluR2 expressed in cell membrane incubated for 1 hr in presence of tritium labeled [3H]-7-((2,5-dioxopyrrolidin-1-yl)methy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMetabotropic glutamate receptor 2(Human)
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM50257556(CHEMBL4101354)
Affinity DataKi:  1.5nMAssay Description:Displacement of [3H]-JNJ46281222 from human metabotropic glutamate receptor 2 expressed in CHOK1 cell membranes after 60 mins by microbeta counting a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM50151481((1R,2R,3R,5R,6R)-2-Amino-3-[(R)-1-(3,4-dichloro-ph...)
Affinity DataKi:  1.61nMAssay Description:Binding affinity towards metabotropic glutamate receptor 2 of rat expressed in CHO cells was determined by using [3H]MGS-0008More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM50618880(CHEMBL5410262)
Affinity DataKi:  1.70nMAssay Description:Binding affinity to human mGluR2 expressed in cell membrane incubated for 1 hr in presence of tritium labeled [3H]-7-((2,5-dioxopyrrolidin-1-yl)methy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMetabotropic glutamate receptor 2(Human)
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM50151434((1R,2R,3R,5R,6R)-2-Amino-6-fluoro-3-((S)-1-naphtha...)
Affinity DataKi:  1.79nMAssay Description:Binding affinity towards metabotropic glutamate receptor 2 of rat expressed in CHO cells was determined by using [3H]MGS-0008More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM212860(US9278960, 2-7 | US9663506, Example 2-7)
Affinity DataKi:  1.80nMAssay Description:Binding affinity to human mGluR2 expressed in cell membrane incubated for 1 hr in presence of tritium labeled [3H]-7-((2,5-dioxopyrrolidin-1-yl)methy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMetabotropic glutamate receptor 2(Human)
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM50257554(CHEMBL4075258)
Affinity DataKi:  1.90nMAssay Description:Displacement of [3H]-JNJ46281222 from human metabotropic glutamate receptor 2 expressed in CHOK1 cell membranes after 60 mins by microbeta counting a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM50257551(CHEMBL4077609)
Affinity DataKi:  1.90nMAssay Description:Displacement of [3H]-JNJ46281222 from human metabotropic glutamate receptor 2 expressed in CHOK1 cell membranes after 60 mins by microbeta counting a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM50257525(CHEMBL4091370)
Affinity DataKi:  2nMAssay Description:Displacement of [3H]-JNJ46281222 from human metabotropic glutamate receptor 2 expressed in CHOK1 cell membranes after 60 mins by microbeta counting a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM50151476((1R,2R,3R,5R,6R)-2-Amino-6-fluoro-3-((R)-1-naphtha...)
Affinity DataKi:  2.01nMAssay Description:Binding affinity towards metabotropic glutamate receptor 2 of rat expressed in CHO cells was determined by using [3H]MGS-0008More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM50151435((1R,2R,3R,5R,6R)-2-Amino-3-(3,4-dichloro-benzyloxy...)
Affinity DataKi:  2.20nMAssay Description:Binding affinity to mGLUR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM50257548(CHEMBL4104081)
Affinity DataKi:  2.20nMAssay Description:Displacement of [3H]-JNJ46281222 from human metabotropic glutamate receptor 2 expressed in CHOK1 cell membranes after 60 mins by microbeta counting a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM50257606(CHEMBL4073628)
Affinity DataKi:  2.20nMAssay Description:Displacement of [3H]-JNJ46281222 from human metabotropic glutamate receptor 2 expressed in CHOK1 cell membranes after 60 mins by microbeta counting a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM50151453((1R,2R,3R,5R,6R)-2-Amino-3-(3,4-difluoro-benzyloxy...)
Affinity DataKi:  2.27nMAssay Description:Binding affinity towards metabotropic glutamate receptor 2 of rat expressed in CHO cells was determined by using [3H]MGS-0008More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM50151435((1R,2R,3R,5R,6R)-2-Amino-3-(3,4-dichloro-benzyloxy...)
Affinity DataKi:  2.38nMAssay Description:Binding affinity towards metabotropic glutamate receptor 2 of rat expressed in CHO cells was determined by using [3H]MGS-0008More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM50151473((1R,2R,3R,5R,6R)-2-Amino-6-fluoro-3-(naphthalen-2-...)
Affinity DataKi:  2.53nMAssay Description:Binding affinity towards metabotropic glutamate receptor 2 of rat expressed in CHO cells was determined by using [3H]MGS-0008More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM50151438((1R,2R,3R,5R,6R)-2-Amino-3-benzhydryloxy-6-fluoro-...)
Affinity DataKi:  2.58nMAssay Description:Binding affinity towards metabotropic glutamate receptor 2 of rat expressed in CHO cells was determined by using [3H]MGS-0008More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM50257524(CHEMBL4080973)
Affinity DataKi:  2.60nMAssay Description:Displacement of [3H]-JNJ46281222 from human metabotropic glutamate receptor 2 expressed in CHOK1 cell membranes after 60 mins by microbeta counting a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM213112(US9278960, 8-19 | US9636337, 8-19)
Affinity DataKi:  2.60nMAssay Description:Binding affinity to human mGluR2 expressed in cell membrane incubated for 1 hr in presence of tritium labeled [3H]-7-((2,5-dioxopyrrolidin-1-yl)methy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMetabotropic glutamate receptor 2(Human)
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM50151478((1R,2R,3R,5R,6R)-2-Amino-3-[bis-(3,4-dichloro-phen...)
Affinity DataKi:  2.61nMAssay Description:Binding affinity towards metabotropic glutamate receptor 2 of rat expressed in CHO cells was determined by using [3H]MGS-0008More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM50089890(4-Amino-2-oxa-bicyclo[3.1.0]hexane-4,6-dicarboxyli...)
Affinity DataKi:  2.70nMAssay Description:Agonist potency against cloned Metabotropic glutamate receptor 2 (mGluR-2).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM50151475((1R,2R,3R,5R,6R)-2-Amino-3-(3-cyano-benzyloxy)-6-f...)
Affinity DataKi:  2.94nMAssay Description:Binding affinity towards metabotropic glutamate receptor 2 of rat expressed in CHO cells was determined by using [3H]MGS-0008More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM50257520(CHEMBL4074421)
Affinity DataKi:  3nMAssay Description:Displacement of [3H]-JNJ46281222 from human metabotropic glutamate receptor 2 expressed in CHOK1 cell membranes after 60 mins by microbeta counting a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM50151482((1R,2R,3R,5R,6R)-2-Amino-3-[(S)-1-(3,4-dichloro-ph...)
Affinity DataKi:  3.05nMAssay Description:Binding affinity towards metabotropic glutamate receptor 2 of rat expressed in CHO cells was determined by using [3H]MGS-0008More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM50151445((1R,2R,3R,5R,6R)-2-Amino-3-[(S)-1-(3,4-dichloro-ph...)
Affinity DataKi:  3.12nMAssay Description:Binding affinity towards metabotropic glutamate receptor 2 of rat expressed in CHO cells was determined by using [3H]MGS-0008More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM50062522((1S,2S)-2-[(1S)-1-amino-1-carboxy-2-(9H-xanthen-9-...)
Affinity DataKi:  3.13nMAssay Description:Binding affinity towards metabotropic glutamate receptor 2 of rat expressed in CHO cells was determined by using [3H]MGS-0008More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMetabotropic glutamate receptor 2(Human)
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM50151447((1R,2R,3R,5R,6R)-2-Amino-3-(4-chloro-benzyloxy)-6-...)
Affinity DataKi:  3.17nMAssay Description:Binding affinity towards metabotropic glutamate receptor 2 of rat expressed in CHO cells was determined by using [3H]MGS-0008More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM50257517(CHEMBL4093657)
Affinity DataKi:  3.20nMAssay Description:Displacement of [3H]-JNJ46281222 from human metabotropic glutamate receptor 2 expressed in CHOK1 cell membranes after 60 mins by microbeta counting a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2019
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM50151464((1R,2R,3R,5R,6R)-2-Amino-3-(3-chloro-benzyloxy)-6-...)
Affinity DataKi:  3.28nMAssay Description:Binding affinity towards metabotropic glutamate receptor 2 of rat expressed in CHO cells was determined by using [3H]MGS-0008More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM50094843((-)-2-Amino-6-fluoro-4-oxo-bicyclo[3.1.0]hexane-2,...)
Affinity DataKi:  3.30nMAssay Description:Tested for binding affinity against Metabotropic glutamate receptor 2 in CHO cells using [3H]-7 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
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