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Found 104 of ic50 for UniProtKB: P08546
TargetDNA polymerase catalytic subunit(Human cytomegalovirus (HCMV strain AD169) )
Pfizer

Curated by ChEMBL
LigandPNGBDBM50210610(CHEMBL395623 | N-(4-chlorobenzyl)-2-(((2-(benzofur...)
Affinity DataIC50:  12nMAssay Description:Inhibition of HCMV DNA polymerase by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase catalytic subunit(Human cytomegalovirus (HCMV strain AD169) )
Pfizer

Curated by ChEMBL
LigandPNGBDBM222924(US9315499, 6011)
Affinity DataIC50:  22nMpH: 7.5Assay Description:The assay conditions are the following: 10 mM HEPES pH 7.5, 25 mM KCl, 7.5 mM NaCl, 5 mM MgCl2, 0.2 mg BSA/mL, 1 mM TCEP, 1.5% glycerol, 5% DMSO, 235...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDNA polymerase catalytic subunit(Human cytomegalovirus (HCMV strain AD169) )
Pfizer

Curated by ChEMBL
LigandPNGBDBM222906(US9315499, 4012)
Affinity DataIC50:  30nMpH: 7.5Assay Description:The assay conditions are the following: 10 mM HEPES pH 7.5, 25 mM KCl, 7.5 mM NaCl, 5 mM MgCl2, 0.2 mg BSA/mL, 1 mM TCEP, 1.5% glycerol, 5% DMSO, 235...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDNA polymerase catalytic subunit(Human cytomegalovirus (HCMV strain AD169) )
Pfizer

Curated by ChEMBL
LigandPNGBDBM50210598((S)-N-(4-chlorobenzyl)-2-(((2-hydroxypropyl)(methy...)
Affinity DataIC50:  35nMAssay Description:Inhibition of HCMV DNA polymerase by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase catalytic subunit(Human cytomegalovirus (HCMV strain AD169) )
Pfizer

Curated by ChEMBL
LigandPNGBDBM50210588((R)-N-(4-chlorobenzyl)-2-(((2-hydroxy-2-(pyrazin-2...)
Affinity DataIC50:  37nMAssay Description:Inhibition of HCMV DNA polymerase by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase catalytic subunit(Human cytomegalovirus (HCMV strain AD169) )
Pfizer

Curated by ChEMBL
LigandPNGBDBM222899(US9315499, 3019)
Affinity DataIC50:  50nMpH: 7.5Assay Description:The assay conditions are the following: 10 mM HEPES pH 7.5, 25 mM KCl, 7.5 mM NaCl, 5 mM MgCl2, 0.2 mg BSA/mL, 1 mM TCEP, 1.5% glycerol, 5% DMSO, 235...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDNA polymerase catalytic subunit(Human cytomegalovirus (HCMV strain AD169) )
Pfizer

Curated by ChEMBL
LigandPNGBDBM222915(US9315499, 4062)
Affinity DataIC50:  59nMpH: 7.5Assay Description:The assay conditions are the following: 10 mM HEPES pH 7.5, 25 mM KCl, 7.5 mM NaCl, 5 mM MgCl2, 0.2 mg BSA/mL, 1 mM TCEP, 1.5% glycerol, 5% DMSO, 235...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDNA polymerase catalytic subunit(Human cytomegalovirus (HCMV strain AD169) )
Pfizer

Curated by ChEMBL
LigandPNGBDBM50210609((R)-N-(3-chlorobenzyl)-2-(((2-hydroxy-2-(pyridin-2...)
Affinity DataIC50:  61nMAssay Description:Inhibition of HCMV DNA polymerase by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase catalytic subunit(Human cytomegalovirus (HCMV strain AD169) )
Pfizer

Curated by ChEMBL
LigandPNGBDBM222903(US9315499, 3038)
Affinity DataIC50:  62nMpH: 7.5Assay Description:The assay conditions are the following: 10 mM HEPES pH 7.5, 25 mM KCl, 7.5 mM NaCl, 5 mM MgCl2, 0.2 mg BSA/mL, 1 mM TCEP, 1.5% glycerol, 5% DMSO, 235...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDNA polymerase catalytic subunit(Human cytomegalovirus (HCMV strain AD169) )
Pfizer

Curated by ChEMBL
LigandPNGBDBM222905(US9315499, 4005)
Affinity DataIC50:  65nMpH: 7.5Assay Description:The assay conditions are the following: 10 mM HEPES pH 7.5, 25 mM KCl, 7.5 mM NaCl, 5 mM MgCl2, 0.2 mg BSA/mL, 1 mM TCEP, 1.5% glycerol, 5% DMSO, 235...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDNA polymerase catalytic subunit(Human cytomegalovirus (HCMV strain AD169) )
Pfizer

Curated by ChEMBL
LigandPNGBDBM222909(US9315499, 4020)
Affinity DataIC50:  65nMpH: 7.5Assay Description:The assay conditions are the following: 10 mM HEPES pH 7.5, 25 mM KCl, 7.5 mM NaCl, 5 mM MgCl2, 0.2 mg BSA/mL, 1 mM TCEP, 1.5% glycerol, 5% DMSO, 235...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDNA polymerase catalytic subunit(Human cytomegalovirus (HCMV strain AD169) )
Pfizer

Curated by ChEMBL
LigandPNGBDBM50210594(CHEMBL247355 | N-(4-chlorobenzyl)-2-(((2-hydroxy-2...)
Affinity DataIC50:  65nMAssay Description:Inhibition of HCMV DNA polymerase by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase catalytic subunit(Human cytomegalovirus (HCMV strain AD169) )
Pfizer

Curated by ChEMBL
LigandPNGBDBM50210615(CHEMBL247554 | N-(4-chlorobenzyl)-2-(((2-(3-cyanop...)
Affinity DataIC50:  66nMAssay Description:Inhibition of HCMV DNA polymerase by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase catalytic subunit(Human cytomegalovirus (HCMV strain AD169) )
Pfizer

Curated by ChEMBL
LigandPNGBDBM222901(US9315499, 3027)
Affinity DataIC50:  71nMpH: 7.5Assay Description:The assay conditions are the following: 10 mM HEPES pH 7.5, 25 mM KCl, 7.5 mM NaCl, 5 mM MgCl2, 0.2 mg BSA/mL, 1 mM TCEP, 1.5% glycerol, 5% DMSO, 235...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDNA polymerase catalytic subunit(Human cytomegalovirus (HCMV strain AD169) )
Pfizer

Curated by ChEMBL
LigandPNGBDBM222910(US9315499, 4024)
Affinity DataIC50:  74nMpH: 7.5Assay Description:The assay conditions are the following: 10 mM HEPES pH 7.5, 25 mM KCl, 7.5 mM NaCl, 5 mM MgCl2, 0.2 mg BSA/mL, 1 mM TCEP, 1.5% glycerol, 5% DMSO, 235...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDNA polymerase catalytic subunit(Human cytomegalovirus (HCMV strain AD169) )
Pfizer

Curated by ChEMBL
LigandPNGBDBM222926(US9315499, 6017)
Affinity DataIC50:  77nMpH: 7.5Assay Description:The assay conditions are the following: 10 mM HEPES pH 7.5, 25 mM KCl, 7.5 mM NaCl, 5 mM MgCl2, 0.2 mg BSA/mL, 1 mM TCEP, 1.5% glycerol, 5% DMSO, 235...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDNA polymerase catalytic subunit(Human cytomegalovirus (HCMV strain AD169) )
Pfizer

Curated by ChEMBL
LigandPNGBDBM50210620(CHEMBL247148 | N-(4-chlorobenzyl)-2-(((2-(furan-2-...)
Affinity DataIC50:  77nMAssay Description:Inhibition of HCMV DNA polymerase by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase catalytic subunit(Human cytomegalovirus (HCMV strain AD169) )
Pfizer

Curated by ChEMBL
LigandPNGBDBM222928(US9315499, 6022)
Affinity DataIC50:  83nMpH: 7.5Assay Description:The assay conditions are the following: 10 mM HEPES pH 7.5, 25 mM KCl, 7.5 mM NaCl, 5 mM MgCl2, 0.2 mg BSA/mL, 1 mM TCEP, 1.5% glycerol, 5% DMSO, 235...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDNA polymerase catalytic subunit(Human cytomegalovirus (HCMV strain AD169) )
Pfizer

Curated by ChEMBL
LigandPNGBDBM50210586(CHEMBL247752 | N-(4-chlorobenzyl)-2-(((2-hydroxy-2...)
Affinity DataIC50:  85nMAssay Description:Inhibition of HCMV DNA polymerase by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase catalytic subunit(Human cytomegalovirus (HCMV strain AD169) )
Pfizer

Curated by ChEMBL
LigandPNGBDBM50210601(CHEMBL246525 | N-(3-chlorobenzyl)-2-(((2-hydroxy-2...)
Affinity DataIC50:  86nMAssay Description:Inhibition of HCMV DNA polymerase by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase catalytic subunit(Human cytomegalovirus (HCMV strain AD169) )
Pfizer

Curated by ChEMBL
LigandPNGBDBM50210616(CHEMBL247556 | N-(4-chlorobenzyl)-2-(((2-hydroxy-2...)
Affinity DataIC50:  87nMAssay Description:Inhibition of HCMV DNA polymerase by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase catalytic subunit(Human cytomegalovirus (HCMV strain AD169) )
Pfizer

Curated by ChEMBL
LigandPNGBDBM50210612(CHEMBL245291 | N-(4-chlorobenzyl)-2-(((2-hydroxy-2...)
Affinity DataIC50:  100nMAssay Description:Inhibition of HCMV DNA polymerase by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase catalytic subunit(Human cytomegalovirus (HCMV strain AD169) )
Pfizer

Curated by ChEMBL
LigandPNGBDBM50210606(CHEMBL396572 | N-(4-chlorobenzyl)-2-(((2-hydroxy-2...)
Affinity DataIC50:  100nMAssay Description:Inhibition of HCMV DNA polymerase by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase catalytic subunit(Human cytomegalovirus (HCMV strain AD169) )
Pfizer

Curated by ChEMBL
LigandPNGBDBM50210617((S)-N-(4-chlorobenzyl)-2-(((2-hydroxy-2-phenylethy...)
Affinity DataIC50:  100nMAssay Description:Inhibition of HCMV DNA polymerase by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase catalytic subunit(Human cytomegalovirus (HCMV strain AD169) )
Pfizer

Curated by ChEMBL
LigandPNGBDBM50210611(CHEMBL247751 | N-(4-chlorobenzyl)-2-(((2-hydroxy-2...)
Affinity DataIC50:  100nMAssay Description:Inhibition of HCMV DNA polymerase by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase catalytic subunit(Human cytomegalovirus (HCMV strain AD169) )
Pfizer

Curated by ChEMBL
LigandPNGBDBM222925(US9315499, 6012)
Affinity DataIC50:  110nMpH: 7.5Assay Description:The assay conditions are the following: 10 mM HEPES pH 7.5, 25 mM KCl, 7.5 mM NaCl, 5 mM MgCl2, 0.2 mg BSA/mL, 1 mM TCEP, 1.5% glycerol, 5% DMSO, 235...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDNA polymerase catalytic subunit(Human cytomegalovirus (HCMV strain AD169) )
Pfizer

Curated by ChEMBL
LigandPNGBDBM222922(US9315499, 6005)
Affinity DataIC50:  120nMpH: 7.5Assay Description:The assay conditions are the following: 10 mM HEPES pH 7.5, 25 mM KCl, 7.5 mM NaCl, 5 mM MgCl2, 0.2 mg BSA/mL, 1 mM TCEP, 1.5% glycerol, 5% DMSO, 235...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDNA polymerase catalytic subunit(Human cytomegalovirus (HCMV strain AD169) )
Pfizer

Curated by ChEMBL
LigandPNGBDBM222919(US9315499, 5015)
Affinity DataIC50:  120nMpH: 7.5Assay Description:The assay conditions are the following: 10 mM HEPES pH 7.5, 25 mM KCl, 7.5 mM NaCl, 5 mM MgCl2, 0.2 mg BSA/mL, 1 mM TCEP, 1.5% glycerol, 5% DMSO, 235...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDNA polymerase catalytic subunit(Human cytomegalovirus (HCMV strain AD169) )
Pfizer

Curated by ChEMBL
LigandPNGBDBM222911(US9315499, 4034)
Affinity DataIC50:  120nMpH: 7.5Assay Description:The assay conditions are the following: 10 mM HEPES pH 7.5, 25 mM KCl, 7.5 mM NaCl, 5 mM MgCl2, 0.2 mg BSA/mL, 1 mM TCEP, 1.5% glycerol, 5% DMSO, 235...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDNA polymerase catalytic subunit(Human cytomegalovirus (HCMV strain AD169) )
Pfizer

Curated by ChEMBL
LigandPNGBDBM222913(US9315499, 4040)
Affinity DataIC50:  130nMpH: 7.5Assay Description:The assay conditions are the following: 10 mM HEPES pH 7.5, 25 mM KCl, 7.5 mM NaCl, 5 mM MgCl2, 0.2 mg BSA/mL, 1 mM TCEP, 1.5% glycerol, 5% DMSO, 235...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDNA polymerase catalytic subunit(Human cytomegalovirus (HCMV strain AD169) )
Pfizer

Curated by ChEMBL
LigandPNGBDBM222921(US9315499, 6003)
Affinity DataIC50:  140nMpH: 7.5Assay Description:The assay conditions are the following: 10 mM HEPES pH 7.5, 25 mM KCl, 7.5 mM NaCl, 5 mM MgCl2, 0.2 mg BSA/mL, 1 mM TCEP, 1.5% glycerol, 5% DMSO, 235...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDNA polymerase catalytic subunit(Human cytomegalovirus (HCMV strain AD169) )
Pfizer

Curated by ChEMBL
LigandPNGBDBM222927(US9315499, 6018)
Affinity DataIC50:  160nMpH: 7.5Assay Description:The assay conditions are the following: 10 mM HEPES pH 7.5, 25 mM KCl, 7.5 mM NaCl, 5 mM MgCl2, 0.2 mg BSA/mL, 1 mM TCEP, 1.5% glycerol, 5% DMSO, 235...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDNA polymerase catalytic subunit(Human cytomegalovirus (HCMV strain AD169) )
Pfizer

Curated by ChEMBL
LigandPNGBDBM50210595(CHEMBL246732 | N-(3-chlorobenzyl)-2-(((2-hydroxy-2...)
Affinity DataIC50:  160nMAssay Description:Inhibition of HCMV DNA polymerase by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase catalytic subunit(Human cytomegalovirus (HCMV strain AD169) )
Pfizer

Curated by ChEMBL
LigandPNGBDBM222914(US9315499, 4056)
Affinity DataIC50:  170nMpH: 7.5Assay Description:The assay conditions are the following: 10 mM HEPES pH 7.5, 25 mM KCl, 7.5 mM NaCl, 5 mM MgCl2, 0.2 mg BSA/mL, 1 mM TCEP, 1.5% glycerol, 5% DMSO, 235...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDNA polymerase catalytic subunit(Human cytomegalovirus (HCMV strain AD169) )
Pfizer

Curated by ChEMBL
LigandPNGBDBM50210614(CHEMBL247357 | N-(4-chlorobenzyl)-2-(((2-hydroxy-2...)
Affinity DataIC50:  175nMAssay Description:Inhibition of HCMV DNA polymerase by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase catalytic subunit(Human cytomegalovirus (HCMV strain AD169) )
Pfizer

Curated by ChEMBL
LigandPNGBDBM222907(US9315499, 4017)
Affinity DataIC50:  180nMpH: 7.5Assay Description:The assay conditions are the following: 10 mM HEPES pH 7.5, 25 mM KCl, 7.5 mM NaCl, 5 mM MgCl2, 0.2 mg BSA/mL, 1 mM TCEP, 1.5% glycerol, 5% DMSO, 235...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDNA polymerase catalytic subunit(Human cytomegalovirus (HCMV strain AD169) )
Pfizer

Curated by ChEMBL
LigandPNGBDBM50210592(CHEMBL247956 | N-(4-chlorobenzyl)-2-(((2-(furan-2-...)
Affinity DataIC50:  180nMAssay Description:Inhibition of HCMV DNA polymerase by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase catalytic subunit(Human cytomegalovirus (HCMV strain AD169) )
Pfizer

Curated by ChEMBL
LigandPNGBDBM222923(US9315499, 6008)
Affinity DataIC50:  180nMpH: 7.5Assay Description:The assay conditions are the following: 10 mM HEPES pH 7.5, 25 mM KCl, 7.5 mM NaCl, 5 mM MgCl2, 0.2 mg BSA/mL, 1 mM TCEP, 1.5% glycerol, 5% DMSO, 235...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDNA polymerase catalytic subunit(Human cytomegalovirus (HCMV strain AD169) )
Pfizer

Curated by ChEMBL
LigandPNGBDBM222908(US9315499, 4018)
Affinity DataIC50:  190nMpH: 7.5Assay Description:The assay conditions are the following: 10 mM HEPES pH 7.5, 25 mM KCl, 7.5 mM NaCl, 5 mM MgCl2, 0.2 mg BSA/mL, 1 mM TCEP, 1.5% glycerol, 5% DMSO, 235...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDNA polymerase catalytic subunit(Human cytomegalovirus (HCMV strain AD169) )
Pfizer

Curated by ChEMBL
LigandPNGBDBM222902(US9315499, 3034)
Affinity DataIC50:  200nMpH: 7.5Assay Description:The assay conditions are the following: 10 mM HEPES pH 7.5, 25 mM KCl, 7.5 mM NaCl, 5 mM MgCl2, 0.2 mg BSA/mL, 1 mM TCEP, 1.5% glycerol, 5% DMSO, 235...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDNA polymerase catalytic subunit(Human cytomegalovirus (HCMV strain AD169) )
Pfizer

Curated by ChEMBL
LigandPNGBDBM50210619(CHEMBL394970 | N-(4-chlorobenzyl)-7-ethyl-2-(((2-(...)
Affinity DataIC50:  200nMAssay Description:Inhibition of HCMV DNA polymerase by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase catalytic subunit(Human cytomegalovirus (HCMV strain AD169) )
Pfizer

Curated by ChEMBL
LigandPNGBDBM222898(US9315499, 3008)
Affinity DataIC50:  200nMpH: 7.5Assay Description:The assay conditions are the following: 10 mM HEPES pH 7.5, 25 mM KCl, 7.5 mM NaCl, 5 mM MgCl2, 0.2 mg BSA/mL, 1 mM TCEP, 1.5% glycerol, 5% DMSO, 235...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDNA polymerase catalytic subunit(Human cytomegalovirus (HCMV strain AD169) )
Pfizer

Curated by ChEMBL
LigandPNGBDBM50210608(CHEMBL246939 | N-(4-chlorobenzyl)-2-(((2-hydroxy-2...)
Affinity DataIC50:  200nMAssay Description:Inhibition of HCMV DNA polymerase by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase catalytic subunit(Human cytomegalovirus (HCMV strain AD169) )
Pfizer

Curated by ChEMBL
LigandPNGBDBM50210603(CHEMBL246524 | N-(3-chlorobenzyl)-2-(((2-(4-fluoro...)
Affinity DataIC50:  203nMAssay Description:Inhibition of HCMV DNA polymerase by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase catalytic subunit(Human cytomegalovirus (HCMV strain AD169) )
Pfizer

Curated by ChEMBL
LigandPNGBDBM222929(US9315499, 7002)
Affinity DataIC50:  210nMpH: 7.5Assay Description:The assay conditions are the following: 10 mM HEPES pH 7.5, 25 mM KCl, 7.5 mM NaCl, 5 mM MgCl2, 0.2 mg BSA/mL, 1 mM TCEP, 1.5% glycerol, 5% DMSO, 235...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDNA polymerase catalytic subunit(Human cytomegalovirus (HCMV strain AD169) )
Pfizer

Curated by ChEMBL
LigandPNGBDBM50210600(CHEMBL246523 | N-(4-fluorobenzyl)-2-(((2-(4-fluoro...)
Affinity DataIC50:  220nMAssay Description:Inhibition of HCMV DNA polymerase by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase catalytic subunit(Human cytomegalovirus (HCMV strain AD169) )
Pfizer

Curated by ChEMBL
LigandPNGBDBM222890(US9315499, 1008)
Affinity DataIC50:  220nMpH: 7.5Assay Description:The assay conditions are the following: 10 mM HEPES pH 7.5, 25 mM KCl, 7.5 mM NaCl, 5 mM MgCl2, 0.2 mg BSA/mL, 1 mM TCEP, 1.5% glycerol, 5% DMSO, 235...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDNA polymerase catalytic subunit(Human cytomegalovirus (HCMV strain AD169) )
Pfizer

Curated by ChEMBL
LigandPNGBDBM50210607(CHEMBL247750 | N-(4-chlorobenzyl)-2-(((2-hydroxy-2...)
Affinity DataIC50:  235nMAssay Description:Inhibition of HCMV DNA polymerase by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase catalytic subunit(Human cytomegalovirus (HCMV strain AD169) )
Pfizer

Curated by ChEMBL
LigandPNGBDBM50210591(CHEMBL245293 | N-(4-chlorobenzyl)-2-((ethyl(2-hydr...)
Affinity DataIC50:  240nMAssay Description:Inhibition of HCMV DNA polymerase by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase catalytic subunit(Human cytomegalovirus (HCMV strain AD169) )
Pfizer

Curated by ChEMBL
LigandPNGBDBM50210602(CHEMBL248160 | N-(4-chlorobenzyl)-2-(((2-(furan-2-...)
Affinity DataIC50:  240nMAssay Description:Inhibition of HCMV DNA polymerase by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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