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TargetMuscarinic acetylcholine receptor M2(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM624953(US20230322745, Compound 24)
Affinity DataIC50: 0.0140nMAssay Description:The M2 receptor membrane protein was prepared at 100 μg/mL by Biology Department of WuXi AppTec, and compounds were serially diluted in a 2.5-fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M2(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM624955(US20230322745, Compound 25)
Affinity DataIC50: 0.0300nMAssay Description:The M2 receptor membrane protein was prepared at 100 μg/mL by Biology Department of WuXi AppTec, and compounds were serially diluted in a 2.5-fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M2(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM50296345(Tiotropium Bromide | (1R,2R,4S,5R,7S)-7-(2-hydroxy...)
Affinity DataIC50: 0.0316nMAssay Description:Displacement of [3H]NMS from human muscarinic M2 receptor expressed in CHO-K1 cells after 16 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM624859(US20230322745, Compound 1 | US20250230148, Compoun...)
Affinity DataIC50: 0.0620nMAssay Description:The M2 receptor membrane protein was prepared at 100 μg/mL by Biology Department of WuXi AppTec, and compounds were serially diluted in a 2.5-fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M2(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM624859(US20230322745, Compound 1 | US20250230148, Compoun...)
Affinity DataIC50: 0.0620nMAssay Description:The M2 receptor membrane protein was prepared at 100 μg/mL by Biology Department of WuXi AppTec, and compound was serially diluted in a 2.5-fold grad...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
TargetMuscarinic acetylcholine receptor M2(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM50296345(Tiotropium Bromide | (1R,2R,4S,5R,7S)-7-(2-hydroxy...)
Affinity DataIC50: 0.0631nMAssay Description:Displacement of [3H]NMS from recombinant human M2 receptor expressed in CHO-K1 cells after 16 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM624956(US20230322745, Compound 28)
Affinity DataIC50: 0.0830nMAssay Description:The M2 receptor membrane protein was prepared at 100 μg/mL by Biology Department of WuXi AppTec, and compounds were serially diluted in a 2.5-fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M2(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM624948(US20230322745, Compound 16 | US20230322745, Compou...)
Affinity DataIC50: 0.104nMAssay Description:The M2 receptor membrane protein was prepared at 100 μg/mL by Biology Department of WuXi AppTec, and compounds were serially diluted in a 2.5-fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M2(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM50296331((3R)-3-{[Hydroxy(di-2-thienyl)acetyl]oxy}-1-(3-phe...)
Affinity DataIC50: 0.126nMAssay Description:Displacement of [3H]NMS from human muscarinic M2 receptor expressed in CHO-K1 cells after 16 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM624948(US20230322745, Compound 16 | US20230322745, Compou...)
Affinity DataIC50: 0.130nMAssay Description:The M2 receptor membrane protein was prepared at 100 μg/mL by Biology Department of WuXi AppTec, and compounds were serially diluted in a 2.5-fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M2(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM50296336((3R)-3-{[(2S)-2-Cyclopentyl-2-hydroxy-2-(2-thienyl...)
Affinity DataIC50: 0.140nMAssay Description:Displacement of [3H]NMS from human muscarinic M2 receptor expressed in CHOK1 cells by microplate scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM624957(US20230322745, Compound 29)
Affinity DataIC50: 0.146nMAssay Description:The M2 receptor membrane protein was prepared at 100 μg/mL by Biology Department of WuXi AppTec, and compounds were serially diluted in a 2.5-fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M2(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM624960(US20230322745, Compound 33)
Affinity DataIC50: 0.153nMAssay Description:The M2 receptor membrane protein was prepared at 100 μg/mL by Biology Department of WuXi AppTec, and compounds were serially diluted in a 2.5-fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M2(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM50417445(AHR-504 | CUVPOSA | GLYCOPYRROLATE)
Affinity DataIC50: 0.158nMAssay Description:Displacement of [3H]NMS from recombinant human M2 receptor expressed in CHO-K1 cells after 16 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM50296343((3R)-3-{[(2S)-2-Hydroxy-2-phenyl-2-(2-thienyl)acet...)
Affinity DataIC50: 0.170nMAssay Description:Displacement of [3H]NMS from human muscarinic M2 receptor expressed in CHOK1 cells by microplate scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM50296331((3R)-3-{[Hydroxy(di-2-thienyl)acetyl]oxy}-1-(3-phe...)
Affinity DataIC50: 0.170nMAssay Description:Displacement of [3H]NMS from human muscarinic M2 receptor expressed in CHOK1 cells by microplate scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM50296341((3R)-3-{[Hydroxy(di-3-thienyl)acetyl]oxy}-1-(3-phe...)
Affinity DataIC50: 0.180nMAssay Description:Displacement of [3H]NMS from human muscarinic M2 receptor expressed in CHOK1 cells by microplate scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM50296329((3R)-3-{[Hydroxy(di-2-thienyl)acetyl]oxy}-1-(2-phe...)
Affinity DataIC50: 0.180nMAssay Description:Displacement of [3H]NMS from human muscarinic M2 receptor expressed in CHOK1 cells by microplate scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM50525115(CHEMBL4582879)
Affinity DataIC50: 0.191nMAssay Description:Competitive displacement of [3H]-NMS from human muscarinic M2 receptor expressed in CHO-K9 cells using 0.2 nM [3H]-NMS after 3 hrs by microbeta2 scin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM50066861(BA-679-BR | Spiriva | Tiotropium Bromide | Tiotrop...)
Affinity DataIC50: 0.200nMAssay Description:Displacement of [3H]NMS from human M2 receptor expressed in CHOK1 cell membranes after 4 hrs by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM50296345(Tiotropium Bromide | (1R,2R,4S,5R,7S)-7-(2-hydroxy...)
Affinity DataIC50: 0.210nMAssay Description:Displacement of [3H]NMS from human muscarinic M2 receptor expressed in CHOK1 cells by microplate scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM50296319((3R)-1-Azabicyclo[2.2.2]oct-3-yl(2S)-hydroxy(pheny...)
Affinity DataIC50: 0.210nMAssay Description:Displacement of [3H]NMS from human muscarinic M2 receptor expressed in CHOK1 cells by microplate scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM624967(US20230322745, Compound 40)
Affinity DataIC50: 0.228nMAssay Description:The M2 receptor membrane protein was prepared at 100 μg/mL by Biology Department of WuXi AppTec, and compounds were serially diluted in a 2.5-fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M2(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM50296321((3R)-1-Azabicyclo[2.2.2]oct-3-yl(2S)-cyclopentyl(h...)
Affinity DataIC50: 0.230nMAssay Description:Displacement of [3H]NMS from human muscarinic M2 receptor expressed in CHOK1 cells by microplate scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM624946(US20230322745, Compound 13)
Affinity DataIC50: 0.240nMAssay Description:The M2 receptor membrane protein was prepared at 100 μg/mL by Biology Department of WuXi AppTec, and compounds were serially diluted in a 2.5-fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M2(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM624961(US20230322745, Compound 34)
Affinity DataIC50: 0.248nMAssay Description:The M2 receptor membrane protein was prepared at 100 μg/mL by Biology Department of WuXi AppTec, and compounds were serially diluted in a 2.5-fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M2(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM50296317((3R)-1-Azabicyclo[2.2.2]oct-3-ylhydroxy(di-2-thien...)
Affinity DataIC50: 0.260nMAssay Description:Displacement of [3H]NMS from human muscarinic M2 receptor expressed in CHOK1 cells by microplate scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM50296320((3R)-1-Azabicyclo[2.2.2]oct-3-yl(2R)-hydroxy(pheny...)
Affinity DataIC50: 0.260nMAssay Description:Displacement of [3H]NMS from human muscarinic M2 receptor expressed in CHOK1 cells by microplate scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM624969(US20230322745, Compound 41)
Affinity DataIC50: 0.268nMAssay Description:The M2 receptor membrane protein was prepared at 100 μg/mL by Biology Department of WuXi AppTec, and compounds were serially diluted in a 2.5-fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M2(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM50296338((3R)-3-{[(9-Methyl-9H-xanthen-9-yl)carbonyl]oxy}-1...)
Affinity DataIC50: 0.270nMAssay Description:Displacement of [3H]NMS from human muscarinic M2 receptor expressed in CHOK1 cells by microplate scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM50296344((3R)-3-{[(2R)-2-Hydroxy-2-phenyl-2-(2-thienyl)acet...)
Affinity DataIC50: 0.310nMAssay Description:Displacement of [3H]NMS from human muscarinic M2 receptor expressed in CHOK1 cells by microplate scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM50296340((3R)-3-[(Di-2-thienylacetyl)oxy]-1-(3-phenoxypropy...)
Affinity DataIC50: 0.350nMAssay Description:Displacement of [3H]NMS from human muscarinic M2 receptor expressed in CHOK1 cells by microplate scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM50296327((3R)-1-Heptyl-3-{[hydroxy(di-2-thienyl)acetyl]oxy}...)
Affinity DataIC50: 0.360nMAssay Description:Displacement of [3H]NMS from human muscarinic M2 receptor expressed in CHOK1 cells by microplate scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM50296334((3R)-3-{[(9-Hydroxy-9H-xanthen-9-yl)carbonyl]oxy}-...)
Affinity DataIC50: 0.360nMAssay Description:Displacement of [3H]NMS from human muscarinic M2 receptor expressed in CHOK1 cells by microplate scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM624947(US20230322745, Compound 14)
Affinity DataIC50: 0.375nMAssay Description:The M2 receptor membrane protein was prepared at 100 μg/mL by Biology Department of WuXi AppTec, and compounds were serially diluted in a 2.5-fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M2(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM50296330((3R)-3-{[Hydroxy(di-2-thienyl)acetyl]oxy}-1-(4-phe...)
Affinity DataIC50: 0.380nMAssay Description:Displacement of [3H]NMS from human muscarinic M2 receptor expressed in CHOK1 cells by microplate scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM50296335((3R)-3-{[Hydroxy(diphenyl)acetyl]oxy}-1-(3-phenoxy...)
Affinity DataIC50: 0.440nMAssay Description:Displacement of [3H]NMS from human muscarinic M2 receptor expressed in CHOK1 cells by microplate scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM50296326((3R)-3-{[Hydroxy(di-2-thienyl)acetyl]oxy}-1-methyl...)
Affinity DataIC50: 0.460nMAssay Description:Displacement of [3H]NMS from human muscarinic M2 receptor expressed in CHOK1 cells by microplate scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM50411207(CHEMBL216927 | CHEMBL553058)
Affinity DataIC50: 0.5nMAssay Description:Inhibitory activity was evaluated against Muscarinic acetylcholine receptor M2 expressed in A9 L cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM50417445(AHR-504 | CUVPOSA | GLYCOPYRROLATE)
Affinity DataIC50: 0.501nMAssay Description:Displacement of [3H]NMS from human muscarinic M2 receptor expressed in CHO-K1 cells after 16 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM50296322((3R)-1-Azabicyclo[2.2.2]oct-3-yl(2R)-cyclopentyl(h...)
Affinity DataIC50: 0.540nMAssay Description:Displacement of [3H]NMS from human muscarinic M2 receptor expressed in CHOK1 cells by microplate scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM50296333((3R)-3-{[(9-Hydroxy-9H-xanthen-9-yl)carbonyl]oxy}-...)
Affinity DataIC50: 0.540nMAssay Description:Displacement of [3H]NMS from human muscarinic M2 receptor expressed in CHOK1 cells by microplate scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM624962(US20230322745, Compound 35)
Affinity DataIC50: 0.588nMAssay Description:The M2 receptor membrane protein was prepared at 100 μg/mL by Biology Department of WuXi AppTec, and compounds were serially diluted in a 2.5-fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M2(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM50066859(CHEMBL3401649)
Affinity DataIC50: 0.600nMAssay Description:Displacement of [3H]NMS from human M2 receptor expressed in CHOK1 cell membranes after 4 hrs by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM50066860(CHEMBL3401648)
Affinity DataIC50: 0.600nMAssay Description:Displacement of [3H]NMS from human M2 receptor expressed in CHOK1 cell membranes after 4 hrs by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM50107697(1-methyl-5-(4-(2-(2-(2-(2-(4-(1-methyl-1,2,5,6-tet...)
Affinity DataIC50: 0.630nMAssay Description:Inhibitory activity was evaluated against Muscarinic acetylcholine receptor M2 expressed in A9 L cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM50296342((3R)-3-[(2,2-Di-2-thienylpropanoyl)oxy]-1-(3-pheno...)
Affinity DataIC50: 0.730nMAssay Description:Displacement of [3H]NMS from human muscarinic M2 receptor expressed in CHOK1 cells by microplate scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM624959(US20230322745, Compound 32)
Affinity DataIC50: 0.814nMAssay Description:The M2 receptor membrane protein was prepared at 100 μg/mL by Biology Department of WuXi AppTec, and compounds were serially diluted in a 2.5-fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M2(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM624965(US20230322745, Compound 38)
Affinity DataIC50: 0.842nMAssay Description:The M2 receptor membrane protein was prepared at 100 μg/mL by Biology Department of WuXi AppTec, and compounds were serially diluted in a 2.5-fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2023
Entry Details
US Patent

TargetMuscarinic acetylcholine receptor M2(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM50066858(CHEMBL3401650)
Affinity DataIC50: 0.900nMAssay Description:Displacement of [3H]NMS from human M2 receptor expressed in CHOK1 cell membranes after 4 hrs by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details Article
PubMed
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