Compile Data Set for Download or QSAR
maximum 50k data
Found 17 of ec50 data for complexid = 50000105,50000153,50000155
LigandPNGBDBM50115916(4-[3-(4-Cyano-benzyl)-3H-imidazol-4-ylmethyl]-pipe...)
Affinity DataEC50:  18nMAssay Description:Inhibition of geranyl-geranylation of C-terminal CAAX sequence of Rap 1a in PSN-1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50130365(4-[1-Amino-1-(3-methyl-3H-imidazol-4-yl)-ethyl]-2-...)
Affinity DataEC50:  47nMAssay Description:Inhibition of Rap1a protein geranylgeranylation in human PSN1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50115928(4-[3-(4-Cyano-benzyl)-3H-imidazol-4-ylmethyl]-pipe...)
Affinity DataEC50:  50nMAssay Description:Inhibition of [1-3H]-GGPP incorporation into biotinylated K4B-Ras peptide by geranylgeranyl transferase in the presence of 5 mM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50115911(4-[3-(4-Cyano-benzyl)-3H-imidazol-4-ylmethyl]-pipe...)
Affinity DataEC50:  71nMAssay Description:Inhibition of [1-3H]-GGPP incorporation into biotinylated K4B-Ras peptide by geranylgeranyl transferase in the presence of 5 mM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50130372(4-[1-Amino-1-(3-methyl-3H-imidazol-4-yl)-ethyl]-2-...)
Affinity DataEC50:  87nMAssay Description:Inhibition of Rap1a protein geranylgeranylation in human PSN1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50409709(CHEMBL439047)
Affinity DataEC50:  140nMAssay Description:Inhibition of Rap1a protein geranylgeranylation in human PSN1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50130378(4-[1-Amino-1-(3-methyl-3H-imidazol-4-yl)-ethyl]-2-...)
Affinity DataEC50:  220nMAssay Description:Inhibition of Rap1a protein geranylgeranylation in human PSN1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50130373(4-[1-Amino-1-(3-methyl-3H-imidazol-4-yl)-ethyl]-2-...)
Affinity DataEC50:  250nMAssay Description:Inhibition of Rap1a protein geranylgeranylation in human PSN1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50143599(2-[3-(3-ETHYL-1-METHYL-2-OXO-AZEPAN-3-YL)-PHENOXY]...)
Affinity DataEC50:  470nMAssay Description:Inhibition of Rap1a protein geranylgeranylation in human PSN1 cellsMore data for this Ligand-Target Pair
LigandPNGBDBM50115923(4-[3-(4-Cyano-benzyl)-2-methyl-3H-imidazol-4-ylmet...)
Affinity DataEC50:  680nMAssay Description:Inhibition of geranyl-geranylation of the C-terminal CAAX sequence of Rap 1a in PSN-1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50409707(CHEMBL2111612)
Affinity DataEC50:  720nMAssay Description:Inhibition of Rap1a protein geranylgeranylation in human PSN1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50112383(17-(5,5,5-trifluoropentyl)-19-oxa-2,5,10,12-tetraa...)
Affinity DataEC50:  800nMAssay Description:Inhibition of the human Geranylgeranyl transferase type I catalyzed incorporation of [3H]-GGPP into a biotinylated peptide corresponding to the C-ter...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50130374(4-[1-Amino-1-(3-methyl-3H-imidazol-4-yl)-ethyl]-2-...)
Affinity DataEC50: >1.00E+3nMAssay Description:Inhibition of Rap1a protein geranylgeranylation in human PSN1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50409708(CHEMBL400694)
Affinity DataEC50:  3.20E+3nMAssay Description:Inhibition of Rap1a protein geranylgeranylation in human PSN1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50112379(1-(3-Chloro-phenyl)-4-{2-[3-(2-methoxy-4'-trifluor...)
Affinity DataEC50:  3.40E+3nMAssay Description:Inhibition of the human Geranylgeranyl transferase type I catalyzed incorporation of [3H]-GGPP into a biotinylated peptide corresponding to the C-ter...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50130368(4-[1-Amino-1-(3-methyl-3H-imidazol-4-yl)-ethyl]-2-...)
Affinity DataEC50:  3.99E+3nMAssay Description:Inhibition of Rap1a protein geranylgeranylation in human PSN1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50097071(4-[(5-{[4-(3-CHLOROPHENYL)-3-OXOPIPERAZIN-1-YL]MET...)
Affinity DataEC50:  6.80E+3nMAssay Description:Inhibition of Geranylgeranyl transferase type IMore data for this Ligand-Target Pair