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Found 224 of ec50 data for complexid = 50000831
TargetDNA topoisomerase 2-alpha/2-beta(Homo sapiens (Human))TBA
LigandPNGBDBM21690(1-cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,...)
Affinity DataEC50:  30nMAssay Description:Inhibitory activity against HeLa cell Topoisomerase IIMore data for this Ligand-Target Pair
In DepthDetails
TargetDNA topoisomerase 2-alpha/2-beta(Homo sapiens (Human))TBA
LigandPNGBDBM50213799(CHEMBL440642)
Affinity DataEC50:  96nMAssay Description:Inhibitory activity against HeLa cell Topoisomerase IIMore data for this Ligand-Target Pair
In DepthDetails
TargetDNA topoisomerase 2-alpha/2-beta(Homo sapiens (Human))TBA
LigandPNGBDBM50213803(CHEMBL428339)
Affinity DataEC50:  98nMAssay Description:Inhibitory activity against HeLa cell Topoisomerase IIMore data for this Ligand-Target Pair
In DepthDetails
TargetDNA topoisomerase 2-alpha/2-beta(Homo sapiens (Human))TBA
LigandPNGBDBM50213812(CHEMBL269139)
Affinity DataEC50:  160nMAssay Description:Inhibitory activity against HeLa cell Topoisomerase IIMore data for this Ligand-Target Pair
In DepthDetails
TargetDNA topoisomerase 2-alpha/2-beta(Homo sapiens (Human))TBA
LigandPNGBDBM50213805(CHEMBL7877)
Affinity DataEC50:  160nMAssay Description:Inhibitory activity against HeLa cell Topoisomerase IIMore data for this Ligand-Target Pair
In DepthDetails
TargetDNA topoisomerase 2-alpha/2-beta(Homo sapiens (Human))TBA
LigandPNGBDBM50213795(CHEMBL268458)
Affinity DataEC50:  330nMAssay Description:Inhibitory activity against HeLa cell Topoisomerase IIMore data for this Ligand-Target Pair
In DepthDetails
TargetDNA topoisomerase 2-alpha/2-beta(Homo sapiens (Human))TBA
LigandPNGBDBM50214091(CHEMBL27233)
Affinity DataEC50:  330nMAssay Description:Inhibition of topoisomerase II purified from HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails
TargetDNA topoisomerase 2-alpha/2-beta(Homo sapiens (Human))TBA
LigandPNGBDBM50214091(CHEMBL27233)
Affinity DataEC50:  330nMAssay Description:In vitro evaluation for inhibitor of human topoisomerase II from HeLa cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha/2-beta(Homo sapiens (Human))TBA
LigandPNGBDBM50213794(CHEMBL7690)
Affinity DataEC50:  360nMAssay Description:Inhibition of Vascular endothelial growth factor receptor 2 (KDR)More data for this Ligand-Target Pair
In DepthDetails
TargetDNA topoisomerase 2-alpha/2-beta(Homo sapiens (Human))TBA
LigandPNGBDBM50286492(2-(4-Amino-cyclohexyl)-5-cyclopropyl-7-(2,6-dimeth...)
Affinity DataEC50:  500nMAssay Description:Compound was tested for topoisomerase II inhibition in purified HeLa cells by SDS/K+ precipitation methodMore data for this Ligand-Target Pair
In DepthDetails Article
TargetDNA topoisomerase 2-alpha/2-beta(Homo sapiens (Human))TBA
LigandPNGBDBM50471783(CHEMBL121666)
Affinity DataEC50:  500nMAssay Description:In vitro evaluation for inhibitor of human topoisomerase II from HeLa cells.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha/2-beta(Homo sapiens (Human))TBA
LigandPNGBDBM50213996(CHEMBL30104)
Affinity DataEC50:  550nMAssay Description:In vitro evaluation for inhibitor of human topoisomerase II from HeLa cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha/2-beta(Homo sapiens (Human))TBA
LigandPNGBDBM50213996(CHEMBL30104)
Affinity DataEC50:  550nMAssay Description:Inhibition of topoisomerase II purified from HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails
TargetDNA topoisomerase 2-alpha/2-beta(Homo sapiens (Human))TBA
LigandPNGBDBM87351(Amsacrine hydrochloride | CHEMBL43 | MLS002153376 ...)
Affinity DataEC50:  720nMAssay Description:In vitro inhibitior of human DNA topoisomerase II from HeLa cells.More data for this Ligand-Target Pair
TargetDNA topoisomerase 2-alpha/2-beta(Homo sapiens (Human))TBA
LigandPNGBDBM87351(Amsacrine hydrochloride | CHEMBL43 | MLS002153376 ...)
Affinity DataEC50:  720nMAssay Description:Tested for inhibitory activity against Topoisomerase II isolated from HeLa cells by using SDS-K+ precipitation methodMore data for this Ligand-Target Pair
In DepthDetails PDB3D3D Structure (crystal)
TargetDNA topoisomerase 2-alpha/2-beta(Homo sapiens (Human))TBA
LigandPNGBDBM87351(Amsacrine hydrochloride | CHEMBL43 | MLS002153376 ...)
Affinity DataEC50:  720nMAssay Description:Inhibitory activity in a cell-free assay of DNA cleavage mediated by purified HeLa cell topoisomerase II.More data for this Ligand-Target Pair
In DepthDetails PDB3D3D Structure (crystal)
TargetDNA topoisomerase 2-alpha/2-beta(Homo sapiens (Human))TBA
LigandPNGBDBM87351(Amsacrine hydrochloride | CHEMBL43 | MLS002153376 ...)
Affinity DataEC50:  720nMAssay Description:Tested for inhibition of topoisomerase II isolated from HeLa cells by DNA-cleavage assayMore data for this Ligand-Target Pair
TargetDNA topoisomerase 2-alpha/2-beta(Homo sapiens (Human))TBA
LigandPNGBDBM87351(Amsacrine hydrochloride | CHEMBL43 | MLS002153376 ...)
Affinity DataEC50:  720nMAssay Description:Inhibitory activity against HeLa cell Topoisomerase IIMore data for this Ligand-Target Pair
In DepthDetails PDB3D3D Structure (crystal)
TargetDNA topoisomerase 2-alpha/2-beta(Homo sapiens (Human))TBA
LigandPNGBDBM87351(Amsacrine hydrochloride | CHEMBL43 | MLS002153376 ...)
Affinity DataEC50:  720nMAssay Description:Compound was tested for topoisomerase II inhibition in purified HeLa cells by SDS/K+ precipitation methodMore data for this Ligand-Target Pair
TargetDNA topoisomerase 2-alpha/2-beta(Homo sapiens (Human))TBA
LigandPNGBDBM87351(Amsacrine hydrochloride | CHEMBL43 | MLS002153376 ...)
Affinity DataEC50:  720nMAssay Description:Inhibition of topoisomerase II purified from HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails PDB3D3D Structure (crystal)
TargetDNA topoisomerase 2-alpha/2-beta(Homo sapiens (Human))TBA
LigandPNGBDBM50127140((-)-etoposide | (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-d...)
Affinity DataEC50:  810nMAssay Description:Tested for inhibition of topoisomerase II isolated from HeLa cells by DNA-cleavage assayMore data for this Ligand-Target Pair
TargetDNA topoisomerase 2-alpha/2-beta(Homo sapiens (Human))TBA
LigandPNGBDBM50127140((-)-etoposide | (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-d...)
Affinity DataEC50:  810nMAssay Description:Inhibitory activity in a cell-free assay of DNA cleavage mediated by purified HeLa cell topoisomerase II.More data for this Ligand-Target Pair
In DepthDetails PDB3D3D Structure (crystal)
TargetDNA topoisomerase 2-alpha/2-beta(Homo sapiens (Human))TBA
LigandPNGBDBM50127140((-)-etoposide | (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-d...)
Affinity DataEC50:  810nMAssay Description:Tested for inhibitory activity against Topoisomerase II isolated from HeLa cells by using SDS-K+ precipitation methodMore data for this Ligand-Target Pair
In DepthDetails PDB3D3D Structure (crystal)
TargetDNA topoisomerase 2-alpha/2-beta(Homo sapiens (Human))TBA
LigandPNGBDBM50127140((-)-etoposide | (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-d...)
Affinity DataEC50:  810nMAssay Description:Compound was tested for topoisomerase II inhibition in purified HeLa cells by SDS/K+ precipitation methodMore data for this Ligand-Target Pair
TargetDNA topoisomerase 2-alpha/2-beta(Homo sapiens (Human))TBA
LigandPNGBDBM50127140((-)-etoposide | (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-d...)
Affinity DataEC50:  810nMAssay Description:Inhibitory activity against HeLa cell Topoisomerase IIMore data for this Ligand-Target Pair
In DepthDetails PDB3D3D Structure (crystal)
TargetDNA topoisomerase 2-alpha/2-beta(Homo sapiens (Human))TBA
LigandPNGBDBM50286484(2-Cyclohexyl-5-cyclopropyl-7-(2,6-dimethyl-pyridin...)
Affinity DataEC50:  900nMAssay Description:Compound was tested for topoisomerase II inhibition in purified HeLa cells by SDS/K+ precipitation methodMore data for this Ligand-Target Pair
In DepthDetails Article
TargetDNA topoisomerase 2-alpha/2-beta(Homo sapiens (Human))TBA
LigandPNGBDBM50212758(CHEMBL133780)
Affinity DataEC50:  980nMAssay Description:Inhibitory activity in a cell-free assay of DNA cleavage mediated by purified HeLa cell topoisomerase II.More data for this Ligand-Target Pair
In DepthDetails
TargetDNA topoisomerase 2-alpha/2-beta(Homo sapiens (Human))TBA
LigandPNGBDBM50471911(CHEMBL342844)
Affinity DataEC50: >1.00E+3nMAssay Description:Concentration of compound at which inhibitory activity detected against DNA topoisomerase IIMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha/2-beta(Homo sapiens (Human))TBA
LigandPNGBDBM50471915(CHEMBL434650)
Affinity DataEC50: >1.00E+3nMAssay Description:Concentration of compound at which inhibitory activity detected against DNA topoisomerase IIMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha/2-beta(Homo sapiens (Human))TBA
LigandPNGBDBM50213294(CHEMBL8063)
Affinity DataEC50:  1.10E+3nMAssay Description:Inhibitory activity against HeLa cell Topoisomerase IIMore data for this Ligand-Target Pair
In DepthDetails
TargetDNA topoisomerase 2-alpha/2-beta(Homo sapiens (Human))TBA
LigandPNGBDBM50213813(CHEMBL7960)
Affinity DataEC50:  1.10E+3nMAssay Description:Inhibitory activity against HeLa cell Topoisomerase IIMore data for this Ligand-Target Pair
In DepthDetails
TargetDNA topoisomerase 2-alpha/2-beta(Homo sapiens (Human))TBA
LigandPNGBDBM50213810(CHEMBL7534)
Affinity DataEC50:  1.20E+3nMAssay Description:Inhibitory activity against HeLa cell Topoisomerase IIMore data for this Ligand-Target Pair
In DepthDetails
TargetDNA topoisomerase 2-alpha/2-beta(Homo sapiens (Human))TBA
LigandPNGBDBM50231257(CHEMBL96510)
Affinity DataEC50:  1.20E+3nMAssay Description:Tested for inhibition of topoisomerase II isolated from HeLa cells by DNA-cleavage assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha/2-beta(Homo sapiens (Human))TBA
LigandPNGBDBM50212721(CHEMBL129840)
Affinity DataEC50:  1.40E+3nMAssay Description:Inhibitory activity in a cell-free assay of DNA cleavage mediated by purified HeLa cell topoisomerase II.More data for this Ligand-Target Pair
In DepthDetails
TargetDNA topoisomerase 2-alpha/2-beta(Homo sapiens (Human))TBA
LigandPNGBDBM50471781(CHEMBL121442)
Affinity DataEC50:  1.60E+3nMAssay Description:In vitro evaluation for inhibitor of human topoisomerase II from HeLa cells.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha/2-beta(Homo sapiens (Human))TBA
LigandPNGBDBM50212858(CHEMBL422791)
Affinity DataEC50:  1.60E+3nMAssay Description:Inhibitory activity in a cell-free assay of DNA cleavage mediated by purified HeLa cell topoisomerase II.More data for this Ligand-Target Pair
In DepthDetails
TargetDNA topoisomerase 2-alpha/2-beta(Homo sapiens (Human))TBA
LigandPNGBDBM50213815(CHEMBL267251)
Affinity DataEC50:  1.60E+3nMAssay Description:Inhibitory activity against HeLa cell Topoisomerase IIMore data for this Ligand-Target Pair
In DepthDetails
TargetDNA topoisomerase 2-alpha/2-beta(Homo sapiens (Human))TBA
LigandPNGBDBM50212726(CHEMBL337666)
Affinity DataEC50:  1.70E+3nMAssay Description:Inhibitory activity in a cell-free assay of DNA cleavage mediated by purified HeLa cell topoisomerase II.More data for this Ligand-Target Pair
In DepthDetails
TargetDNA topoisomerase 2-alpha/2-beta(Homo sapiens (Human))TBA
LigandPNGBDBM50286501(5-Cyclopropyl-2-(3-dimethylamino-propyl)-7-(2,6-di...)
Affinity DataEC50:  1.70E+3nMAssay Description:Compound was tested for topoisomerase II inhibition in purified HeLa cells by SDS/K+ precipitation methodMore data for this Ligand-Target Pair
In DepthDetails Article
TargetDNA topoisomerase 2-alpha/2-beta(Homo sapiens (Human))TBA
LigandPNGBDBM50286485(5-Cyclopropyl-7-(2,6-dimethyl-pyridin-4-yl)-6,8-di...)
Affinity DataEC50:  1.70E+3nMAssay Description:Compound was tested for topoisomerase II inhibition in purified HeLa cells by SDS/K+ precipitation methodMore data for this Ligand-Target Pair
In DepthDetails Article
TargetDNA topoisomerase 2-alpha/2-beta(Homo sapiens (Human))TBA
LigandPNGBDBM50286494(5-Cyclopropyl-2-(4-dimethylamino-cyclohexyl)-7-(2,...)
Affinity DataEC50:  1.70E+3nMAssay Description:Compound was tested for topoisomerase II inhibition in purified HeLa cells by SDS/K+ precipitation methodMore data for this Ligand-Target Pair
In DepthDetails Article
TargetDNA topoisomerase 2-alpha/2-beta(Homo sapiens (Human))TBA
LigandPNGBDBM50212604(CHEMBL422265)
Affinity DataEC50:  1.90E+3nMAssay Description:Inhibitory activity in a cell-free assay of DNA cleavage mediated by purified HeLa cell topoisomerase II.More data for this Ligand-Target Pair
In DepthDetails
TargetDNA topoisomerase 2-alpha/2-beta(Homo sapiens (Human))TBA
LigandPNGBDBM50213811(CHEMBL7769)
Affinity DataEC50:  2.10E+3nMAssay Description:Inhibitory activity against HeLa cell Topoisomerase IIMore data for this Ligand-Target Pair
In DepthDetails
TargetDNA topoisomerase 2-alpha/2-beta(Homo sapiens (Human))TBA
LigandPNGBDBM50212796(CHEMBL334608)
Affinity DataEC50:  2.30E+3nMAssay Description:Inhibitory activity in a cell-free assay of DNA cleavage mediated by purified HeLa cell topoisomerase II.More data for this Ligand-Target Pair
In DepthDetails
TargetDNA topoisomerase 2-alpha/2-beta(Homo sapiens (Human))TBA
LigandPNGBDBM50212458(CHEMBL132656)
Affinity DataEC50:  2.40E+3nMAssay Description:Inhibitory activity in a cell-free assay of DNA cleavage mediated by purified HeLa cell topoisomerase II.More data for this Ligand-Target Pair
In DepthDetails
TargetDNA topoisomerase 2-alpha/2-beta(Homo sapiens (Human))TBA
LigandPNGBDBM50286486(5-Cyclopropyl-2-(2-dimethylamino-ethyl)-7-(2,6-dim...)
Affinity DataEC50:  2.60E+3nMAssay Description:Compound was tested for topoisomerase II inhibition in purified HeLa cells by SDS/K+ precipitation methodMore data for this Ligand-Target Pair
In DepthDetails Article
TargetDNA topoisomerase 2-alpha/2-beta(Homo sapiens (Human))TBA
LigandPNGBDBM50212464(CHEMBL449700)
Affinity DataEC50:  2.60E+3nMAssay Description:Inhibitory activity in a cell-free assay of DNA cleavage mediated by purified HeLa cell topoisomerase II.More data for this Ligand-Target Pair
In DepthDetails
TargetDNA topoisomerase 2-alpha/2-beta(Homo sapiens (Human))TBA
LigandPNGBDBM50286474(5-Cyclopropyl-7-(2,6-dimethyl-pyridin-4-yl)-6,8-di...)
Affinity DataEC50:  2.70E+3nMAssay Description:Compound was tested for topoisomerase II inhibition in purified HeLa cells by SDS/K+ precipitation methodMore data for this Ligand-Target Pair
In DepthDetails Article
TargetDNA topoisomerase 2-alpha/2-beta(Homo sapiens (Human))TBA
LigandPNGBDBM50286474(5-Cyclopropyl-7-(2,6-dimethyl-pyridin-4-yl)-6,8-di...)
Affinity DataEC50:  2.70E+3nMAssay Description:Inhibitory activity in a cell-free assay of DNA cleavage mediated by purified HeLa cell topoisomerase II.More data for this Ligand-Target Pair
In DepthDetails
TargetDNA topoisomerase 2-alpha/2-beta(Homo sapiens (Human))TBA
LigandPNGBDBM50214148(CHEMBL283395)
Affinity DataEC50:  3.00E+3nMAssay Description:In vitro evaluation for inhibitor of human topoisomerase II from HeLa cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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